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[191708_s_at]

Description F57C12.5 /REP_DB=WormBase Gene ID /WP=CE25015 /GEN=mrp-1 /TR=Q9N2N3 /GB=AAD31550.2 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=ABC transporter
Cluster 6grp_highest_10_10 > 22      6grp_high1_10_10 > 02      4grp_highest_8_8 > 41      4grp_high_8_8 > 42      6grp_highest_nonorm > 22      6grp_total > 23      4grp_total > 54      6grp_highest_sub > De      6grp_cgc > 30      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1940
1 2 3 4 range
A 2478.8
(3)
P 		1497.2
(-0.2)
P 		1411.4
(-0.5)
P 		629.6
(-3)
P 		1849
B 2440.2
(3)
P 		1681.5
(0.6)
P 		1407.3
(-0.3)
P 		538.9
(-3)
P 		1901
C 2415.6
(3)
P 		1648.1
(0.3)
P 		1355.3
(-0.8)
P 		720.8
(-3)
P 		1695
avr 2444.9
(3) 		1608.9
(0.2) 		1391.3
(-0.5) 		629.8
(-3) 		1815

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1450
1 2 3 4 5 6 range
A 2128.9
(3)
P 		1984.8
(2.2)
P 		1561.4
(0)
P 		1490.7
(-0.4)
P 		1008.1
(-2.9)
P 		985.9
(-3)
P 		1143
B 2119.2
(3)
P 		1747.5
(1.3)
P 		1467.7
(0)
P 		1442.8
(-0.1)
P 		841.8
(-2.9)
P 		815.5
(-3)
P 		1304
C 2265
(3)
P 		1886.2
(1.3)
P 		2213.4
(2.8)
P 		1681.3
(0.5)
P 		891.2
(-3)
P 		1001
(-2.5)
P 		1374
avr 2171
(3) 		1872.8
(1.6) 		1747.5
(1) 		1538.3
(-0) 		913.7
(-3) 		934.1
(-2.9) 		1257
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 810
1 2 3 4 range
A 902.5
(3)
P 		325
(-1.3)
P 		369
(-1)
P 		92.2
(-3)
P 		810
B 778.2
(3)
P 		415.3
(-0.3)
P 		326.1
(-1.1)
P 		114.8
(-3)
P 		663
C 799.6
(3)
P 		473.8
(0.1)
P 		472.4
(0.1)
P 		121.5
(-3)
P 		678
avr 826.8
(3) 		404.7
(-0.5) 		389.2
(-0.7) 		109.5
(-3) 		717

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 600
1 2 3 4 5 6 range
A 392.5
(-1)
P 		705.9
(3)
P 		340
(-1.7)
P 		378.1
(-1.2)
P 		304.2
(-2.2)
P 		240
(-3)
P 		466
B 737.4
(3)
P 		581.7
(0.8)
P 		356.4
(-2.3)
P 		382.1
(-1.9)
P 		342
(-2.5)
P 		304.1
(-3)
P 		433
C 839.5
(3)
P 		575.5
(0.1)
P 		563.4
(-0)
P 		338.1
(-2.5)
P 		288.4
(-3)
P 		335.1
(-2.5)
P 		551
avr 656.5
(3) 		621
(2.4) 		419.9
(-0.9) 		366.1
(-1.8) 		311.5
(-2.7) 		293.1
(-3) 		363
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191708_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18483
Sequence Type Exemplar sequence
Representative Public ID F57C12.5 NCBI
Target Description F57C12.5 /REP_DB=WormBase Gene ID /WP=CE25015 /GEN=mrp-1 /TR=Q9N2N3 /GB=AAD31550.2 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=ABC transporter
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001029548(11), NM_171938(11), NM_001029547(11), NM_075721(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001029548 NCBI Caenorhabditis elegans Multidrug Resistance Protein family member (mrp-1) (mrp-1) mRNA, complete cds. 11/11 None
NM_171938 NCBI Caenorhabditis elegans Multidrug Resistance Protein family member (mrp-1) (mrp-1) mRNA, complete cds. 11/11 None
NM_001029547 NCBI Caenorhabditis elegans Multidrug Resistance Protein family member (mrp-1) (mrp-1) mRNA, complete cds. 11/11 None
NM_075721 NCBI Caenorhabditis elegans Multidrug Resistance Protein family member (mrp-1) (mrp-1) mRNA, complete cds. 11/11 None
SNAP00000008052 ENSEMBL cdna:SNAP chromosome:CEL140:X:576488:579618:-1 11/11 None
F57C12.5d.3 ENSEMBL cdna:known chromosome:CEL140:X:576319:587483:-1 gene:F57C12.5 11/11 None
F57C12.5d.4 ENSEMBL cdna:known chromosome:CEL140:X:576319:587414:-1 gene:F57C12.5 11/11 None
F57C12.5d.2 ENSEMBL cdna:known chromosome:CEL140:X:576319:580138:-1 gene:F57C12.5 11/11 None
F57C12.5d.1 ENSEMBL cdna:known chromosome:CEL140:X:576319:579566:-1 gene:F57C12.5 11/11 None
F57C12.5c ENSEMBL cdna:known chromosome:CEL140:X:576488:587463:-1 gene:F57C12.5 11/11 None
F57C12.5a ENSEMBL cdna:known chromosome:CEL140:X:576488:587414:-1 gene:F57C12.5 11/11 None
F57C12.5b ENSEMBL cdna:known chromosome:CEL140:X:576488:587414:-1 gene:F57C12.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:576487-587414(-) 100.0 100.0
Public Domain and Genome References
Ensembl F57C12.5
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAM69107 Multidrug resistance protein family protein 1, isoform c [Caenorhabditis elegans] ref|NP_741702.1| Multidrug Resistance Protein family member (mrp-1) [Caenorhabditis elegans] 0.0
blast AAD31550 Multidrug resistance protein family protein 1, isoform a [Caenorhabditis elegans] ref|NP_001024718.1| Multidrug Resistance Protein family member (mrp-1) [Caenorhabditis elegans] 0.0
blast AAL06032 Multidrug resistance protein family protein 1, isoform b [Caenorhabditis elegans] ref|NP_508122.2| Multidrug Resistance Protein family member (mrp-1) [Caenorhabditis elegans] 0.0
blast AAB07021 multidrug resistance related protein 0.0
blast ABA03118 Multidrug resistance protein family protein 1, isoform e [Caenorhabditis elegans] 0.0
blast BAD88409.1 multidrug resistance-associated protein [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR003439 EMBL-EBI ABC transporter 7.8E-47
Pfam IPR001140 EMBL-EBI ABC transporter, transmembrane region 9.6E-48
Pfam IPR001140 EMBL-EBI ABC transporter, transmembrane region 4.6E-37
Pfam IPR003439 EMBL-EBI ABC transporter 3.6E-37
Pfam IPR003439 EMBL-EBI ABC transporter 7.8E-47
Pfam IPR001140 EMBL-EBI ABC transporter, transmembrane region 4.1E-29
Pfam IPR003439 EMBL-EBI ABC transporter 7.8E-47
Pfam IPR001140 EMBL-EBI ABC transporter, transmembrane region 2.6E-31
Pfam IPR001140 EMBL-EBI ABC transporter, transmembrane region 1.1E-8
Pfam IPR003439 EMBL-EBI ABC transporter 8.2E-17
Pfam IPR003439 EMBL-EBI ABC transporter 8.3E-23
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_741702.1 14 39-56,69-91,106-128,133-155,332-354,410-432,436-458,523-545,555-577,966-988,1028-1050,1091-1113,1117-1136,1200-1222
NP_001024718.1 12 39-56,69-91,106-128,133-155,332-354,410-432,436-458,523-545,555-577,966-988,1028-1050,1100-1122
NP_508122.2 14 39-56,69-91,106-128,133-155,332-354,410-432,436-458,523-545,555-577,966-988,1028-1050,1087-1109,1119-1136,1200-1222
F57C12.5c 14 39-56,69-91,106-128,133-155,332-354,410-432,436-458,523-545,555-577,966-988,1028-1050,1091-1113,1117-1136,1200-1222
F57C12.5a 12 39-56,69-91,106-128,133-155,332-354,410-432,436-458,523-545,555-577,966-988,1028-1050,1100-1122
F57C12.5b 14 39-56,69-91,106-128,133-155,332-354,410-432,436-458,523-545,555-577,966-988,1028-1050,1087-1109,1119-1136,1200-1222
SNAP00000008052 1 17-39
Sequence
Target Sequence 
>C. ELEGANS:191708_S_AT
cggagccggaaagagttccctcacacttgcacttttccgtattatcgaagccgacggtgg
atgcattgagattgatggaactaatattgctgatctcctgcttgaacagctgagaagccg
gttgacaatcgtgccacaggatccagtattgttttcaggaacaatgcgtatgaacttgga
tcccttctttgcatttagcgatgatcaaatttgggaagcgttgcgaaacgctcatttaga
ttcatttgtaaaatctttgcaagaaggtcttcatcatcatatttctgaaggaggagagaa
cttgagtgttggacaacgacaactaatctgccttgctcgagctcttctcagaaaaaccaa
agtgttggtgttagatgaagccgccgctgcagttgacgtcgaaaccgatagtcttcttca
aaaaaccattcgagagcagttcaaagattgtactgttctcacaattgcccatcgactgaa
tacggttatggatagtgatcgtctacttgttctcgacaaaggttgtgtagccgagtttga
cactccgaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CGGAGCCGGAAAGAGTTCCCTCACA 180 1 3987 Antisense
AATATTGCTGATCTCCTGCTTGAAC 506 173 4069 Antisense
AGAAGCCGGTTGACAATCGTGCCAC 207 73 4099 Antisense
ATCGTGCCACAGGATCCAGTATTGT 463 35 4114 Antisense
TGCGTATGAACTTGGATCCCTTCTT 288 583 4151 Antisense
CAACGACAACTAATCTGCCTTGCTC 637 187 4300 Antisense
GACGTCGAAACCGATAGTCTTCTTC 22 379 4381 Antisense
TTGTACTGTTCTCACAATTGCCCAT 445 705 4434 Antisense
AATTGCCCATCGACTGAATACGGTT 410 177 4449 Antisense
AGTGATCGTCTACTTGTTCTCGACA 25 61 4480 Antisense
GTGTAGCCGAGTTTGACACTCCGAA 301 485 4511 Antisense
Sequence Source Affymetrix Proprietary Database