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[191666_s_at] carboxylesterase

Description R12A1.4 /REP_DB=WormBase Gene ID /WP=CE17207 /GEN=ges-1 /TR=O16702 /GB=AAB66165.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=carboxylesterase
Cluster 6grp_highest_10_10 > 25      6grp_high1_10_10 > 41      4grp_highest_8_8 > 25      4grp_high_8_8 > 59      6grp_highest_nonorm > 33      6grp_total > 52      4grp_total > 60      6grp_highest_sub > 03      6grp_cgc > 92      6grp_high1_sub > 03      6grp_cgc_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 940
1 2 3 4 range
A 938.3
(2.4)
P 		867.2
(1.8)
P 		1016
(3)
P 		295.6
(-3)
P 		720
B 861.8
(0.7)
P 		952.4
(1.3)
P 		1217.1
(3)
P 		276.7
(-3)
P 		940
C 849.7
(2.3)
P 		783.3
(1.7)
P 		923
(3)
P 		302
(-3)
P 		621
avr 883.3
(1.7) 		867.6
(1.5) 		1052
(3) 		291.4
(-3) 		761

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1437
1 2 3 4 5 6 range
A 1434.3
(-0.2)
P 		1615.2
(0.7)
P 		2088.3
(3)
P 		1658.2
(0.9)
P 		1122.1
(-1.8)
P 		871.5
(-3)
P 		1217
B 1212.3
(-1.8)
P 		1353.2
(-1.2)
P 		2217.8
(3)
P 		1585.7
(-0)
P 		1143.4
(-2.2)
P 		970.2
(-3)
P 		1248
C 1143.3
(-2.5)
P 		1397.1
(-1.3)
P 		2308
(3)
P 		1237.7
(-2.1)
P 		1117.6
(-2.7)
P 		1048.2
(-3)
P 		1260
avr 1263.3
(-1.6) 		1455.2
(-0.6) 		2204.7
(3) 		1493.9
(-0.4) 		1127.7
(-2.2) 		963.3
(-3) 		1241
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 298
1 2 3 4 range
A 341.6
(3)
P 		188.2
(-0.1)
P 		265.6
(1.5)
P 		43.3
(-3)
P 		298
B 274.8
(2.8)
P 		235.2
(1.7)
P 		282
(3)
P 		59
(-3)
P 		223
C 281.3
(2.1)
P 		225.2
(0.9)
P 		321.7
(3)
P 		50.9
(-3)
P 		271
avr 299.2
(3) 		216.2
(1) 		289.8
(2.8) 		51.1
(-3) 		248

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 375
1 2 3 4 5 6 range
A 264.4
(-2.1)
P 		574.5
(3)
P 		454.8
(1)
P 		420.6
(0.5)
P 		338.6
(-0.9)
P 		212.2
(-3)
P 		362
B 421.8
(-1)
P 		450.4
(0)
P 		538.5
(3)
P 		420
(-1)
P 		464.6
(0.5)
P 		361.8
(-3)
P 		177
C 423.8
(0.1)
P 		426.3
(0.1)
P 		587.4
(3)
P 		248.9
(-3)
P 		361.6
(-1)
P 		350.9
(-1.2)
P 		339
avr 370
(-1.3) 		483.7
(1.8) 		526.9
(3) 		363.2
(-1.5) 		388.3
(-0.8) 		308.3
(-3) 		219
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191666_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.15435
Sequence Type Exemplar sequence
Representative Public ID R12A1.4 NCBI
Target Description R12A1.4 /REP_DB=WormBase Gene ID /WP=CE17207 /GEN=ges-1 /TR=O16702 /GB=AAB66165.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=carboxylesterase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_071010(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_071010 NCBI Caenorhabditis elegans R12A1.4 (carboxylesterase) mRNA, complete cds. 11/11 None
R12A1.4.3 ENSEMBL cdna:known chromosome:CEL140:V:1427479:1431968:-1 gene:R12A1.4 11/11 None
R12A1.4.2 ENSEMBL cdna:known chromosome:CEL140:V:1427479:1431968:-1 gene:R12A1.4 11/11 None
R12A1.4.1 ENSEMBL cdna:known chromosome:CEL140:V:1427479:1431966:-1 gene:R12A1.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:1427535-1431966(-) 100.0 100.0
Public Domain and Genome References
Gene Title carboxylesterase
Gene Symbol ges-1
Ensembl R12A1.4
Entrez Gene 178633 Entrez gene
SwissProt Q04457 EMBL-EBI
WormBase CE28763 Wormbase
Functional Annotations
Ortholog
ID Title Organism
RT-U34:M20629_S_AT esterase 2 rn
RG-U34A:M20629_S_AT esterase 2 rn
RG-U34A:D00362_S_AT esterase 2 rn
RAE230A:1371100_AT esterase 2 rn
RAT230_2:1371100_AT esterase 2 rn
Protein Similarities
Method ID Description E-Value
blast AAB66165 Abnormal gut esterase protein 1 [Caenorhabditis elegans] ref|NP_503411.1| R12A1.4 [Caenorhabditis elegans] sp|Q04457|EST1_CAEEL Gut esterase 1 precursor (Non-specific carboxylesterase) gb|AAA28057.1| elastase 0.0
blast T32061 gut-specific carboxylesterase ges-1 - Caenorhabditis elegans 0.0
blast Q04456 Gut esterase 1 precursor (Non-specific carboxylesterase) emb|CAE62343.1| Hypothetical protein CBG06418 [Caenorhabditis briggsae] gb|AAA28056.1| esterase 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:191666_S_AT
aggatctcaatgggttctatgtggatcgatattcagagctgctctcggatatcaccttca
acgtgccaattcttcgtgaaatcactagcagagttgagagaaaaactccagtttggacat
accgtatggatcactacgataaaaatatttggaaaaagcatattccagagcaagcaagag
gctctccgcatgctaatgaataccattatctatttgatatgccagtgatggcaaaaattg
atatgaagaaagaaccggacagttggattcaaaatgatctgattgatatggtgatttcat
ttgctaaaaccggagttccccaaatagaagatgtagaatggagaccagttagcgatccag
acgacgtaaactttttgaatatcagatctgatggggtctcaattgagcatggtcttttcc
aagaacctctcgctttctggaacgaactgcgccaacgagaagga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGGATCTCAATGGGTTCTATGTGGA 313 57 1202 Antisense
GTGGATCGATATTCAGAGCTGCTCT 61 491 1222 Antisense
TCAGAGCTGCTCTCGGATATCACCT 345 623 1234 Antisense
GATATCACCTTCAACGTGCCAATTC 388 425 1249 Antisense
GAGCAAGCAAGAGGCTCTCCGCATG 306 391 1369 Antisense
GGCTCTCCGCATGCTAATGAATACC 123 539 1381 Antisense
GACCAGTTAGCGATCCAGACGACGT 592 383 1544 Antisense
GATCTGATGGGGTCTCAATTGAGCA 20 419 1586 Antisense
GCATGGTCTTTTCCAAGAACCTCTC 487 309 1608 Antisense
AACCTCTCGCTTTCTGGAACGAACT 627 147 1625 Antisense
GAACGAACTGCGCCAACGAGAAGGA 4 347 1641 Antisense
Sequence Source Affymetrix Proprietary Database