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[191644_at] myotubularin-like protein

Description Y110A7A.5 /REP_DB=WormBase Gene ID /WP=CE24125 /TR=Q9N589 /GB=AAF60423.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=myotubularin-like protein
Cluster 6grp_highest_10_10 > 54      6grp_high1_10_10 > 45      4grp_highest_8_8 > 33      4grp_high_8_8 > 58      6grp_highest_nonorm > 74      6grp_total > 30      4grp_total > 61      6grp_cgc > 25      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 201
1 2 3 4 range
A 575.3
(2)
P 		515.9
(-1.2)
P 		592.9
(3)
P 		483.3
(-3)
P 		110
B 550.1
(2.9)
P 		550.3
(3)
P 		529.2
(-3)
P 		529.1
(-3)
P 		21
C 575.6
(3)
P 		567.9
(2.7)
P 		558.3
(2.4)
P 		391.8
(-3)
P 		184
avr 567
(3) 		544.7
(1.6) 		560.1
(2.6) 		468.1
(-3) 		99

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 338
1 2 3 4 5 6 range
A 678.2
(3)
P 		603.2
(-0.1)
P 		595.3
(-0.5)
P 		569.4
(-1.6)
P 		535.1
(-3)
P 		588.5
(-0.8)
P 		143
B 795.3
(3)
P 		765.5
(1.8)
P 		763.6
(1.7)
P 		748.2
(1.1)
P 		667.6
(-2.1)
P 		645.3
(-3)
P 		150
C 531.7
(-2.4)
P 		833.6
(3)
P 		577.6
(-1.5)
P 		808.6
(2.6)
P 		495.3
(-3)
P 		724.2
(1.1)
P 		338
avr 668.4
(0.7) 		734.1
(3) 		645.5
(-0.2) 		708.7
(2.1) 		566
(-3) 		652.7
(0.1) 		168
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 143
1 2 3 4 range
A 209.5
(3)
P 		112
(-1.2)
P 		155
(0.6)
P 		70.7
(-3)
P 		139
B 175.4
(3)
P 		135.9
(-0.8)
P 		122.6
(-2.1)
P 		112.8
(-3)
P 		63
C 190.5
(2.8)
P 		163.3
(1.5)
P 		194.6
(3)
P 		66.1
(-3)
P 		129
avr 191.8
(3) 		137.1
(-0) 		157.4
(1.1) 		83.2
(-3) 		109

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 152
1 2 3 4 5 6 range
A 125
(-3)
P 		214.5
(3)
P 		129.6
(-2.7)
P 		144.4
(-1.7)
P 		161.5
(-0.6)
P 		143.3
(-1.8)
P 		90
B 276.7
(3)
P 		254.8
(1.6)
P 		185.4
(-3)
P 		198.2
(-2.2)
P 		271.2
(2.6)
P 		240.6
(0.6)
P 		91
C 197.1
(-0.2)
P 		254.4
(3)
P 		147
(-3)
P 		162.6
(-2.1)
P 		160.3
(-2.3)
P 		242.4
(2.3)
P 		107
avr 199.6
(0.1) 		241.2
(3) 		154
(-3) 		168.4
(-2) 		197.7
(0) 		208.8
(0.8) 		87
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191644_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2513
Sequence Type Exemplar sequence
Representative Public ID Y110A7A.5 NCBI
Target Description Y110A7A.5 /REP_DB=WormBase Gene ID /WP=CE24125 /TR=Q9N589 /GB=AAF60423.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=myotubularin-like protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059130(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059130 NCBI Caenorhabditis elegans MTM (myotubularin) family member (mtm-1) (mtm-1) mRNA, complete cds. 11/11 None
SNAP00000029213 ENSEMBL cdna:SNAP chromosome:CEL140:I:5134758:5137841:1 11/11 None
Y110A7A.5 ENSEMBL cdna:known chromosome:CEL140:I:5134770:5137960:1 gene:Y110A7A.5 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000029222 2/11 Cross Hyb Matching Probes None
GENEFINDER00000029239 6/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:5134757-5137841(+) 100.0 100.0
Public Domain and Genome References
Gene Title myotubularin-like protein
Gene Symbol mtm-1
Ensembl Y110A7A.5
Entrez Gene 172148 Entrez gene
SwissProt Q9N589 EMBL-EBI
WormBase CE30707 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.20831.1.S1_S_AT similar to Myotubularin cfa
CANINE_2:CFAAFFX.29200.1.S1_S_AT similar to Myotubularin cfa
CHICKEN:GGA.12543.1.S1_AT myotubularin 1 gga
CHICKEN:GGAAFFX.22799.1.S1_AT myotubularin 1 gga
HG-U133_PLUS_2:204101_AT myotubularin 1 hs
HG-U133A:204101_AT myotubularin 1 hs
HG-U133A_2:204101_AT myotubularin 1 hs
HUGENEFL:U46024_AT myotubularin 1 hs
U133_X3P:G4557895_3P_S_AT myotubularin 1 hs
U133_X3P:4874998C_3P_S_AT myotubularin 1 hs
U133_X3P:204101_3P_AT myotubularin 1 hs
HG-U133A_2:36920_AT myotubularin 1 hs
HG-FOCUS:36920_AT myotubularin 1 hs
HG-U133_PLUS_2:36920_AT myotubularin 1 hs
HG-U133A:36920_AT myotubularin 1 hs
HG-U95AV2:36920_AT myotubularin 1 hs
HG-U95C:66106_R_AT myotubularin 1 hs
HG-U95B:45924_AT Myotubularin 1 hs
MOE430A:1454904_AT X-linked myotubular myopathy gene 1 mm
MOUSE430A_2:1454904_AT X-linked myotubular myopathy gene 1 mm
MOUSE430_2:1454904_AT X-linked myotubular myopathy gene 1 mm
MOUSE430_2:1434278_AT X-linked myotubular myopathy gene 1 mm
MOE430A:1434278_AT X-linked myotubular myopathy gene 1 mm
MOUSE430A_2:1434278_AT X-linked myotubular myopathy gene 1 mm
MOE430A:1416934_AT X-linked myotubular myopathy gene 1 mm
MOUSE430A_2:1416934_AT X-linked myotubular myopathy gene 1 mm
MOUSE430_2:1416934_AT X-linked myotubular myopathy gene 1 mm
MU11KSUBA:AA517050_S_AT X-linked myotubular myopathy gene 1 mm
MU11KSUBA:AA204432_F_AT X-linked myotubular myopathy gene 1 mm
MU11KSUBA:AA590400_F_AT X-linked myotubular myopathy gene 1 mm
MG-U74AV2:96199_AT X-linked myotubular myopathy gene 1 mm
MG-U74AV2:98524_F_AT X-linked myotubular myopathy gene 1 mm
MG-U74BV2:111331_AT X-linked myotubular myopathy gene 1 mm
MG-U74CV2:169980_I_AT X-linked myotubular myopathy gene 1 (Mtm1), mRNA mm
MU19KSUBC:TC38255_AT X-linked myotubular myopathy gene 1 (Mtm1), mRNA mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6470 protein amino acid dephosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4721 phosphoprotein phosphatase activity inferred from electronic annotation QuickGO AmiGO
4725 protein tyrosine phosphatase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAF60423 Mtm (myotubularin) family protein 1 [Caenorhabditis elegans] ref|NP_491531.2| MTM (myotubularin) family member (mtm-1) [Caenorhabditis elegans] 0.0
blast CAE65746 Hypothetical protein CBG10832 [Caenorhabditis briggsae] 0.0
blast CAE74473 Hypothetical protein CBG22220 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR010569 EMBL-EBI Myotubularin-related 6.6E-57
Pfam IPR010569 EMBL-EBI Myotubularin-related 6.6E-57
Sequence
Target Sequence 
>C. ELEGANS:191644_AT
gatcgaactgcacagctgacgtcgttggcaatgattcaactcgactcctattaccgtaca
attgaaggatttatcgttttgattgagaaggaatggtgtagctttggtcataaatttgga
gagagaatcggtcacggcgacgataactacagcgatggagaacgatctcccgtatttgtt
caattctgtgactgcctatggcaaattatgcgacaatttccatgggcatttgaatttaca
caagaactgctaatttgtatgctcgatgagctctacgcttgcagatatggaacatttttg
tacaattccgaaaaaatccggctgaaggataagaaatgcgatgaaacgacgatatcgttc
tggtcctatgttttggaaaataaaaagaaattcagaaatccaatgtttaagcatggaaaa
tccaataaagtgataaacgtaaacccatctctctgcggtttacatgtatggattgattac
tacgcccgatcgaatccatatgtagttactccaaatcatgaggatgttcaacagccaggc
gcacagt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GATCGAACTGCACAGCTGACGTCGT 390 417 1171 Antisense
TGATTCAACTCGACTCCTATTACCG 267 563 1202 Antisense
GGTCACGGCGACGATAACTACAGCG 440 501 1300 Antisense
GATCTCCCGTATTTGTTCAATTCTG 434 419 1334 Antisense
TCAATTCTGTGACTGCCTATGGCAA 646 633 1350 Antisense
GAACTGCTAATTTGTATGCTCGATG 324 349 1414 Antisense
CTCGATGAGCTCTACGCTTGCAGAT 485 231 1432 Antisense
GATAAACGTAAACCCATCTCTCTGC 426 421 1602 Antisense
ATCTCTCTGCGGTTTACATGTATGG 36 33 1617 Antisense
TGATTACTACGCCCGATCGAATCCA 82 437 1644 Antisense
GATGTTCAACAGCCAGGCGCACAGT 595 409 1693 Antisense
Sequence Source Affymetrix Proprietary Database