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[191638_s_at] protein-tyrosine phosphatase /// protein-tyrosine phosphatase

Description F10G8.1 /REP_DB=WormBase Gene ID /WP=CE20664 /TR=Q9XVU4 /GB=CAB02287.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster 6grp_total > 98      4grp_total > 02      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 115
1 2 3 4 range
A 4.5
(-3)
A 		4.2
(-3)
A 		4.1
(-3)
A 		109.3
(3)
P 		105
B 11.1
(3)
A 		3.2
(-2)
A 		1.7
(-3)
A 		10.4
(2.6)
A 		9
C 2.5
(-3)
A 		6.2
(-2.8)
A 		2.8
(-3)
A 		117
(3)
P 		115
avr 6
(-2.8) 		4.5
(-2.9) 		2.9
(-3) 		78.9
(3) 		76

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 318
1 2 3 4 5 6 range
A 4.4
(-3)
A 		1.8
(-3)
A 		7
(-2.9)
A 		75
(-1.6)
A 		193.3
(0.6)
P 		319.5
(3)
P 		318
B 3.4
(-3)
A 		4.1
(-3)
A 		4.7
(-3)
A 		52
(-1.9)
A 		273.1
(3)
P 		271
(3)
P 		270
C 2.4
(-3)
A 		29.8
(-2.5)
A 		2.3
(-3)
A 		26.6
(-2.5)
A 		246.3
(1.7)
P 		311.2
(3)
P 		309
avr 3.4
(-3) 		11.9
(-2.8) 		4.7
(-3) 		51.2
(-2) 		237.6
(1.7) 		300.6
(3) 		297
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 19
1 2 3 4 range
A 1.7
(-2.7)
A 		0.9
(-3)
A 		1.1
(-2.9)
A 		16
(3)
P 		15
B 3.6
(3)
A 		0.8
(-2.3)
A 		0.4
(-3)
A 		2.2
(0.4)
A 		3
C 0.8
(-3)
A 		1.8
(-2.7)
A 		1
(-2.9)
A 		19.7
(3)
P 		19
avr 2
(-2.4) 		1.2
(-2.8) 		0.8
(-3) 		12.6
(3) 		12

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 110
1 2 3 4 5 6 range
A 0.8
(-3)
A 		0.6
(-3)
A 		1.5
(-2.9)
A 		19
(-1.6)
A 		58.3
(1.5)
P 		77.8
(3)
P 		77
B 1.2
(-3)
A 		1.4
(-3)
A 		1.1
(-3)
A 		13.8
(-2.3)
A 		111
(3)
P 		101
(2.5)
P 		110
C 0.9
(-3)
A 		9.1
(-2.5)
A 		0.6
(-3)
A 		5.3
(-2.7)
A 		79.7
(1.6)
P 		104.2
(3)
P 		104
avr 1
(-3) 		3.7
(-2.8) 		1.1
(-3) 		12.7
(-2.2) 		83
(2.3) 		94.3
(3) 		93
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191638_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2450
Sequence Type Exemplar sequence
Representative Public ID F10G8.1 NCBI
Target Description F10G8.1 /REP_DB=WormBase Gene ID /WP=CE20664 /TR=Q9XVU4 /GB=CAB02287.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060246(11), NM_059471(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060246 NCBI Caenorhabditis elegans F10G8.1 (F10G8.1) mRNA, complete cds. 11/11 None
NM_059471 NCBI Caenorhabditis elegans C55B7.3 (C55B7.3) mRNA, complete cds. 11/11 None
SNAP00000038301 ENSEMBL cdna:SNAP chromosome:CEL140:I:6505588:6509495:1 11/11 None
GENEFINDER00000038314 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:6505588:6509495:1 11/11 None
GENEFINDER00000036100 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:10027627:10029156:1 9/11 None
SNAP00000036090 ENSEMBL cdna:SNAP chromosome:CEL140:I:10027827:10029156:1 11/11 None
C55B7.3 ENSEMBL cdna:known chromosome:CEL140:I:6507976:6509495:1 gene:C55B7.3 11/11 None
F10G8.1 ENSEMBL cdna:known chromosome:CEL140:I:10027827:10029156:1 gene:F10G8.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:10027757-10029087(+) 100.0 100.0
chrI:6508093-6509424(+) 97.73 97.73
Public Domain and Genome References
Gene Title protein-tyrosine phosphatase
protein-tyrosine phosphatase
Ensembl C55B7.3
F10G8.1
Entrez Gene 172359 Entrez gene
184322 Entrez gene
SwissProt Q966M2 EMBL-EBI
Q9XVU4 EMBL-EBI
WormBase CE09014 Wormbase
CE36642 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6470 protein amino acid dephosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4721 phosphoprotein phosphatase activity inferred from electronic annotation QuickGO AmiGO
4725 protein tyrosine phosphatase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB02287 Hypothetical protein F10G8.1 [Caenorhabditis elegans] ref|NP_492647.2| F10G8.1 [Caenorhabditis elegans] 0.0
blast NP_491872 C55B7.3 [Caenorhabditis elegans] gb|AAK68274.1| Hypothetical protein C55B7.3 [Caenorhabditis elegans] 0.0
blast NP_491871 Acyl CoA DeHydrogenase family member (acdh-1) [Caenorhabditis elegans] gb|AAK68275.1| Acyl coa dehydrogenase protein 1, isoform a [Caenorhabditis elegans] 0.0
blast CAE67208 Hypothetical protein CBG12644 [Caenorhabditis briggsae] 0.0
Protein Families
Method ID Description E-Value
ec ACDM_HUMAN (P11310) Acyl-CoA dehydrogenase, medium-chain specific, mitochondrial precursor (EC 1.3.99.3) (MCAD) 1.0E-142
ec ACDM_HUMAN (P11310) Acyl-CoA dehydrogenase, medium-chain specific, mitochondrial precursor (EC 1.3.99.3) (MCAD) 1.0E-163
Protein Domains
Database ID Description E-Value
scop a.2.3.Chaperone J-domain All alpha proteins; Long alpha-hairpin; Chaperone J-domain; Chaperone J-domain 2.29999995231628
scop a.2.3.Chaperone J-domain All alpha proteins; Long alpha-hairpin; Chaperone J-domain; Chaperone J-domain 0.730000019073486
scop a.2.3.Chaperone J-domain All alpha proteins; Long alpha-hairpin; Chaperone J-domain; Chaperone J-domain 0.670000016689301
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 1.4E-100
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 1.6E-98
Pfam IPR006090 EMBL-EBI Acyl-CoA dehydrogenase, C-terminal 3.1E-68
Pfam IPR006091 EMBL-EBI Acyl-CoA dehydrogenase, central domain 1.0E-48
Pfam IPR006092 EMBL-EBI Acyl-CoA dehydrogenase, N-terminal 6.3E-30
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 1.4E-100
Pfam IPR006090 EMBL-EBI Acyl-CoA dehydrogenase, C-terminal 1.7E-43
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 1.4E-100
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 1.1E-30
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 3.4E-43
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 3.2E-99
Sequence
Target Sequence 
>C. ELEGANS:191638_S_AT
ggtcgagtacatttttatgctgtgcaactttctggagaaaggagcaaaaaagtgtttcga
atacttcccgagcaagaagggtgatgtgatggactttgacgaaggtggtcagaagatctc
agttaaatgcgaatcttcggtgacgttcattgaaagttttcattattcgttccgtgctga
tgcaaaggcaaacgtcactgcaacagagattgtgatcgaaggacctggcgagaaaactcg
aaagaccactcattatcactggaatgactggccagatcgcggtgttccagctgcggatat
ggctgttcttgagcttctggagaatgctagaccatcaaaaggtcctatcgttgtccattg
ttctgcaggtattggacgcactggctctgttgtgatgttggagtacatcatggatcaact
gctcgcaggccagatcattgatgatggggaaaagatcttggtcaaaatttgcgagcaacg
taacaattcaatccagacggatgcccagtatctgttcgtgcatcaagtcattctcaacta
cttccgca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGTCGAGTACATTTTTATGCTGTGC 616 501 444 Antisense
GTGTTTCGAATACTTCCCGAGCAAG 568 485 495 Antisense
GCAAAGGCAAACGTCACTGCAACAG 301 317 625 Antisense
TGGAATGACTGGCCAGATCGCGGTG 283 547 703 Antisense
ATGGCTGTTCTTGAGCTTCTGGAGA 428 51 742 Antisense
AAAGGTCCTATCGTTGTCCATTGTT 562 121 781 Antisense
ACGCACTGGCTCTGTTGTGATGTTG 532 91 819 Antisense
ACATCATGGATCAACTGCTCGCAGG 578 103 848 Antisense
TCAACTGCTCGCAGGCCAGATCATT 365 631 858 Antisense
AGACGGATGCCCAGTATCTGTTCGT 173 71 938 Antisense
CAAGTCATTCTCAACTACTTCCGCA 261 185 967 Antisense
Sequence Source Affymetrix Proprietary Database