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[191633_s_at] adenylate cyclase

Description F17C8.1 /REP_DB=WormBase Gene ID /WP=CE00955 /GEN=acy-1 /TR=Q19523 /GB=CAA84795.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=adenylate cyclase
Cluster 6grp_highest_10_10 > 42      6grp_high1_10_10 > 13      4grp_highest_8_8 > 51      4grp_high_8_8 > 24      6grp_highest_nonorm > 51      6grp_total > 14      4grp_total > 39      6grp_highest_sub > 02      6grp_cgc > 30      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 571
1 2 3 4 range
A 849.3
(3)
P 		368.9
(-2.2)
P 		300.2
(-3)
P 		390.3
(-2)
P 		549
B 700.4
(3)
P 		278.4
(-3)
P 		343.9
(-2.1)
P 		415.5
(-1.1)
P 		422
C 749.8
(3)
P 		306.9
(-3)
P 		311.4
(-2.9)
P 		412
(-1.6)
P 		443
avr 766.5
(3) 		318.1
(-3) 		318.5
(-3) 		405.9
(-1.8) 		448

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 484
1 2 3 4 5 6 range
A 759.9
(3)
P 		713.5
(2.3)
P 		529.5
(-0.7)
P 		489.1
(-1.3)
P 		467.5
(-1.6)
P 		381.8
(-3)
P 		378
B 842.2
(3)
P 		775.8
(2.2)
P 		560.7
(-0.5)
P 		733.3
(1.6)
P 		358.7
(-3)
P 		503.9
(-1.2)
P 		484
C 610.6
(0.3)
P 		790.3
(3)
P 		589.4
(-0)
P 		503.4
(-1.3)
P 		393.7
(-3)
P 		487.2
(-1.6)
P 		397
avr 737.6
(2.6) 		759.9
(3) 		559.9
(-0.4) 		575.3
(-0.1) 		406.6
(-3) 		457.6
(-2.1) 		353
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 252
1 2 3 4 range
A 309.2
(3)
P 		80.1
(-2.5)
P 		78.5
(-2.5)
P 		57.1
(-3)
P 		252
B 223.4
(3)
P 		68.8
(-3)
P 		79.7
(-2.6)
P 		88.5
(-2.2)
P 		155
C 248.2
(3)
P 		88.2
(-2.4)
P 		108.5
(-1.7)
P 		69.5
(-3)
P 		179
avr 260.3
(3) 		79
(-2.8) 		88.9
(-2.5) 		71.7
(-3) 		189

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 200
1 2 3 4 5 6 range
A 140.1
(-1.2)
P 		253.8
(3)
P 		115.3
(-2.2)
P 		124
(-1.8)
P 		141.1
(-1.2)
P 		92.9
(-3)
P 		161
B 293.1
(3)
P 		258.2
(1.7)
P 		136.2
(-3)
P 		194.2
(-0.8)
P 		145.7
(-2.6)
P 		187.9
(-1)
P 		157
C 226.3
(2.4)
P 		241.1
(3)
P 		150
(-0.9)
P 		101.2
(-3)
P 		127.4
(-1.9)
P 		163.1
(-0.3)
P 		140
avr 219.8
(1.4) 		251
(3) 		133.8
(-3) 		139.8
(-2.7) 		138.1
(-2.8) 		148
(-2.3) 		117
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191633_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7716
Sequence Type Exemplar sequence
Representative Public ID F17C8.1 NCBI
Target Description F17C8.1 /REP_DB=WormBase Gene ID /WP=CE00955 /GEN=acy-1 /TR=Q19523 /GB=CAA84795.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=adenylate cyclase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065569(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065569 NCBI Caenorhabditis elegans Adenylyl CYclase family member (acy-1) (acy-1) mRNA, complete cds. 11/11 None
GENEFINDER00000012153 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:4724695:4730526:1 11/11 None
SNAP00000012142 ENSEMBL cdna:SNAP chromosome:CEL140:III:4724849:4730526:1 11/11 None
F17C8.1 ENSEMBL cdna:known chromosome:CEL140:III:4722174:4730832:1 gene:F17C8.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:4722173-4730526(+) 100.0 100.0
Public Domain and Genome References
Gene Title adenylate cyclase
Gene Symbol acy-1
Ensembl F17C8.1
Entrez Gene 175622 Entrez gene
SwissProt Q19523 EMBL-EBI
WormBase CE00955 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.29348.1.S1_S_AT similar to Adenylate cyclase, type IX (ATP pyrophosphate-lyase 9) (Adenylyl cyclase 9) cfa
DROSOPHILA_2:1636219_AT Adenylyl cyclase 35C dm
DROSGENOME1:143962_AT Adenylyl cyclase 35C dm
CHICKEN:GGA.1773.1.S1_AT adenylate cyclase 9 gga
CHICKEN:GGA.1773.1.S2_AT adenylate cyclase 9 gga
HG-U133_PLUS_2:204498_S_AT adenylate cyclase 9 hs
HG-U133A_2:204498_S_AT adenylate cyclase 9 hs
HG-U133A:204498_S_AT adenylate cyclase 9 hs
HU35KSUBB:RC_Z40718_AT adenylate cyclase 9 hs
U133_X3P:G4557258_3P_A_AT adenylate cyclase 9 hs
U133_X3P:HS.20196.0.S2_3P_AT adenylate cyclase 9 hs
HG-U133A_2:204497_AT adenylate cyclase 9 hs
HG-FOCUS:204497_AT adenylate cyclase 9 hs
HG-U133_PLUS_2:204497_AT adenylate cyclase 9 hs
HG-U133A:204497_AT adenylate cyclase 9 hs
HG-U95AV2:33800_AT adenylate cyclase 9 hs
HG-U133_PLUS_2:215400_X_AT Adenylate cyclase 9 hs
HG-U133A_2:215400_X_AT Adenylate cyclase 9 hs
HG-U133A:215400_X_AT Adenylate cyclase 9 hs
U133_X3P:HS.306624.0.S1_3P_X_AT Adenylate cyclase 9 hs
U133_X3P:HS.306624.0.S1_3P_AT Adenylate cyclase 9 hs
HG-U95B:42469_AT Adenylate cyclase 9 hs
HG-U95C:60127_AT Adenylate cyclase 9 hs
HU35KSUBB:RC_H54687_AT Adenylate cyclase 9 hs
HU35KSUBB:RC_R98753_AT Adenylate cyclase 9 hs
HU35KSUBB:RC_T64004_AT Adenylate cyclase 9 hs
MOUSE430A_2:1418586_AT adenylate cyclase 9 mm
MOE430A:1418586_AT adenylate cyclase 9 mm
MOUSE430_2:1418586_AT adenylate cyclase 9 mm
MU11KSUBA:U30602_S_AT adenylate cyclase 9 mm
MG-U74AV2:92527_AT adenylate cyclase 9 mm
MU11KSUBA:AA407393_RC_AT Adenylate cyclase 9 (Adcy9), mRNA mm
MU19KSUBA:TC23039_F_AT Adenylate cyclase 9 (Adcy9), mRNA mm
MU19KSUBB:TC32492_F_AT Adenylate cyclase 9 (Adcy9), mRNA mm
MU19KSUBB:TC32492_I_AT Adenylate cyclase 9 (Adcy9), mRNA mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5886 plasma membrane inferred from curator QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4383 guanylate cyclase activity inferred from electronic annotation QuickGO AmiGO
4016 adenylate cyclase activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA84795 Hypothetical protein F17C8.1 [Caenorhabditis elegans] ref|NP_497970.1| Adenylyl CYclase family member (acy-1) [Caenorhabditis elegans] 0.0
blast CAE71145 Hypothetical protein CBG18000 [Caenorhabditis briggsae] 0.0
blast NP_033754 adenylate cyclase 9 [Mus musculus] emb|CAA90570.1| adenylyl cyclase type 9 [Mus musculus] 5.0E-99
Protein Domains
Database ID Description E-Value
Pfam IPR001054 EMBL-EBI Guanylate cyclase 7.2E-73
Pfam IPR001054 EMBL-EBI Guanylate cyclase 4.9E-56
Pfam IPR001054 EMBL-EBI Guanylate cyclase 7.2E-73
Pfam IPR001054 EMBL-EBI Guanylate cyclase 4.9E-56
Pfam IPR001054 EMBL-EBI Guanylate cyclase 7.2E-73
Pfam IPR001054 EMBL-EBI Guanylate cyclase 4.9E-56
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_497970.1 11 68-87,94-116,121-143,164-186,201-223,771-793,803-825,842-861,871-888,895-917,968-987
F17C8.1 11 68-87,94-116,121-143,164-186,201-223,771-793,803-825,842-861,871-888,895-917,968-987
GENEFINDER00000012153 9 13-35,59-81,94-116,666-688,693-715,735-757,769-791,796-815,861-883
SNAP00000012142 9 4-21,42-64,79-101,649-671,681-703,720-739,749-766,773-795,846-865
Sequence
Target Sequence 
>C. ELEGANS:191633_S_AT
tgtactgttcgcttcaatcactaattggaatgatatgtatgaagagaatttcgaaggggg
cagagaattcttgagagttctcaatgaagttattggtgactttgatgagcttctcgatcg
gccggacttcacgcatattgaaaaaatcaaaacaattgggcctgcgtatatggcagcaag
tggattgaatccagaacgaaaaaagaatatgttgcatccaaaagagcatctatatcagat
ggttgattttgcattggcagttcaacatgtactcagtgttttcaacgaggatttgctcaa
ttttgattttgtttgcaagttaggacttaatattggacccgtcactgctggtgtcattgg
aacaacaaagttgtactacgatatctggggtgacactgtaaacattgctagccgaatgta
cagcaccggagttttaaatcgcattcaagtatcacaacacacacgagaatatctcctgga
tcggtatgaattcgagttccgcgatcatattgaagtcaagggaattgatggaggaatgga
tacttatcttttggttggtcga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGTACTGTTCGCTTCAATCACTAAT 405 559 3159 Antisense
CTTTGATGAGCTTCTCGATCGGCCG 487 223 3258 Antisense
GACTTAATATTGGACCCGTCACTGC 307 369 3482 Antisense
CCCGTCACTGCTGGTGTCATTGGAA 390 259 3496 Antisense
GTACTACGATATCTGGGGTGACACT 500 459 3531 Antisense
GTGACACTGTAAACATTGCTAGCCG 65 483 3548 Antisense
GCTAGCCGAATGTACAGCACCGGAG 646 301 3565 Antisense
AGCACCGGAGTTTTAAATCGCATTC 571 75 3580 Antisense
ATCGCATTCAAGTATCACAACACAC 515 37 3596 Antisense
GAATTCGAGTTCCGCGATCATATTG 529 323 3646 Antisense
GGATACTTATCTTTTGGTTGGTCGA 524 509 3696 Antisense
Sequence Source Affymetrix Proprietary Database