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[191611_at] glutathione S-transferases

Description F35E8.11 /REP_DB=WormBase Gene ID /WP=CE15961 /TR=O45456 /GB=CAB04302.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Glutathione S-transferases.
Cluster 6grp_highest_10_10 > 72      6grp_high1_10_10 > 27      4grp_highest_8_8 > 56      4grp_high_8_8 > 36      6grp_highest_nonorm > 90      6grp_total > 17      4grp_total > 36      6grp_highest_sub > Cu      6grp_cgc > 06      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 198
1 2 3 4 range
A 312.8
(2.5)
P 		294.6
(1)
P 		243.3
(-3)
P 		319.7
(3)
P 		76
B 320.4
(-0.5)
P 		382
(3)
P 		303.5
(-1.4)
P 		275.3
(-3)
P 		107
C 323.9
(0.6)
P 		401.9
(3)
P 		203.8
(-3)
P 		298
(-0.1)
P 		198
avr 319
(0.8) 		359.5
(3) 		250.2
(-3) 		297.7
(-0.4) 		109

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 218
1 2 3 4 5 6 range
A 294.8
(3)
P 		77.3
(-3)
P 		135.1
(-1.4)
P 		125.6
(-1.7)
P 		122
(-1.8)
P 		148.3
(-1)
P 		218
B 260.1
(3)
P 		147.9
(-1.2)
P 		188
(0.3)
P 		112.4
(-2.5)
P 		98.4
(-3)
P 		136.3
(-1.6)
P 		162
C 198.9
(1)
P 		248.9
(3)
P 		112.4
(-2.4)
P 		110.7
(-2.5)
P 		98.2
(-3)
P 		146.4
(-1.1)
P 		151
avr 251.3
(3) 		158
(-0.9) 		145.2
(-1.4) 		116.2
(-2.6) 		106.2
(-3) 		143.7
(-1.4) 		145
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 69
1 2 3 4 range
A 113.9
(3)
P 		63.9
(-1.5)
P 		63.6
(-1.5)
P 		46.8
(-3)
P 		67
B 102.2
(3)
P 		94.4
(1.9)
P 		70.3
(-1.4)
P 		58.7
(-3)
P 		44
C 107.2
(2.2)
P 		115.6
(3)
P 		71
(-1.1)
P 		50.2
(-3)
P 		65
avr 107.8
(3) 		91.3
(1.2) 		68.3
(-1.2) 		51.9
(-3) 		56

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 68
1 2 3 4 5 6 range
A 54.4
(3)
P 		27.5
(-3)
P 		29.4
(-2.6)
P 		31.9
(-2)
P 		36.8
(-0.9)
P 		36.1
(-1.1)
P 		27
B 90.5
(3)
P 		49.2
(-1.1)
P 		45.6
(-1.4)
P 		29.8
(-3)
P 		40
(-2)
P 		50.8
(-0.9)
P 		61
C 73.7
(2.8)
P 		75.9
(3)
P 		28.6
(-2.3)
P 		22.3
(-3)
P 		31.8
(-1.9)
P 		49
(-0)
P 		54
avr 72.9
(3) 		50.9
(0.1) 		34.5
(-2.1) 		28
(-3) 		36.2
(-1.9) 		45.3
(-0.7) 		45
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191611_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14092
Sequence Type Exemplar sequence
Representative Public ID F35E8.11 NCBI
Target Description F35E8.11 /REP_DB=WormBase Gene ID /WP=CE15961 /TR=O45456 /GB=CAB04302.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Glutathione S-transferases.
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074585(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074585 NCBI Caenorhabditis elegans CaDmium Responsive family member (cdr-1) (cdr-1) mRNA, complete cds. 11/11 None
SNAP00000019517 ENSEMBL cdna:SNAP chromosome:CEL140:V:15923960:15925357:1 11/11 None
GENEFINDER00000019533 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:15923960:15925357:1 11/11 None
F35E8.11 ENSEMBL cdna:known chromosome:CEL140:V:15923947:15925402:1 gene:F35E8.11 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:15923959-15925357(+) 100.0 100.0
Public Domain and Genome References
Gene Title glutathione S-transferases
Gene Symbol cdr-1
Ensembl F35E8.11
Entrez Gene 180064 Entrez gene
SwissProt O45456 EMBL-EBI
WormBase CE15961 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
46686 response to cadmium ion inferred from direct assay QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from sequence similarity QuickGO AmiGO
5764 lysosome inferred from direct assay QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB04302 Hypothetical protein F35E8.11 [Caenorhabditis elegans] ref|NP_506986.1| CaDmium Responsive family member (cdr-1) [Caenorhabditis elegans] gb|AAG30870.1| cadmium-inducible lysosomal protein CDR-1 [Caenorhabditis elegans] 1.0E-150
blast CAE74956 Hypothetical protein CBG22847 [Caenorhabditis briggsae] 1.0E-109
blast AAU43721 cadmium-inducible lysosomal protein CDR-6 [Caenorhabditis elegans] emb|CAA99802.1| Hypothetical protein K01D12.12 [Caenorhabditis elegans] ref|NP_506113.1| CaDmium Responsive family member (cdr-6) [Caenorhabditis elegans] 1.0E-101
Protein Domains
Database ID Description E-Value
Pfam IPR004046 EMBL-EBI Glutathione S-transferase, C-terminal 0.0011
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_506986.1 2 7-29,158-180
F35E8.11 2 7-29,158-180
SNAP00000019517 2 7-29,158-180
GENEFINDER00000019533 2 7-29,158-180
Sequence
Target Sequence 
>C. ELEGANS:191611_AT
gagattatcacatgcacctctgaacgctctcggaatggattggtccctttcgttgaactc
aatggagagcacattgctgattctgatcttatcgaaatgcgcttgagatcacattttaaa
attccgtcgcttccaactgagctggaaactcaatctgttgctctaagcaagtttgcagat
caccatttgttcttcgtacttatacgatttaaaattgctgtcgacgaattctacaaaacc
attattgaaataatcggtctcccaaccttcctgaatttccttctcatgccccttttgaag
gctataatcgggaaaaatgtctacaacaaatgtcagggagccattggagattttgaattg
agtgagctcgacgagattcttcacagagatttgcgaatcgtagagaacaccttggccaag
aaaaagtttcttttcggggaggaaatcacggcggcggatgcaacagtcttctctcaattg
gcaactgtctattatccattccgcaatcacat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAGATTATCACATGCACCTCTGAAC 401 397 244 Antisense
ACCTCTGAACGCTCTCGGAATGGAT 226 87 259 Antisense
ATTGGTCCCTTTCGTTGAACTCAAT 668 1 282 Antisense
TTTAAAATTCCGTCGCTTCCAACTG 423 673 358 Antisense
AAACTCAATCTGTTGCTCTAAGCAA 52 127 389 Antisense
GCAGATCACCATTTGTTCTTCGTAC 359 313 418 Antisense
TGAAATAATCGGTCTCCCAACCTTC 684 571 489 Antisense
TTCCTTCTCATGCCCCTTTTGAAGG 369 699 520 Antisense
GAATCGTAGAGAACACCTTGGCCAA 340 329 638 Antisense
AGGAAATCACGGCGGCGGATGCAAC 344 55 683 Antisense
TCTATTATCCATTCCGCAATCACAT 134 615 731 Antisense
Sequence Source Affymetrix Proprietary Database