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[191541_at] glutathione S-transferase

Description C54D10.1 /REP_DB=WormBase Gene ID /WP=CE05497 /TR=Q18831 /GB=CAA99803.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Glutathione S-transferases.
Cluster 6grp_highest_10_10 > 74      6grp_high1_10_10 > 47      4grp_highest_8_8 > 04      4grp_high_8_8 > 38      6grp_highest_nonorm > 67      6grp_total > 47      4grp_total > 33      6grp_highest_sub > Cu      6grp_cgc > 17      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1843
1 2 3 4 range
A 751.9
(-3)
P 		1915.3
(1.3)
P 		2363.2
(3)
P 		1244
(-1.2)
P 		1611
B 1142.6
(-3)
P 		2195.1
(3)
P 		1947.1
(1.6)
P 		1857.6
(1.1)
P 		1053
C 1169.4
(-3)
P 		2080.6
(0.8)
P 		1594.7
(-1.2)
P 		2594.6
(3)
P 		1425
avr 1021.3
(-3) 		2063.7
(3) 		1968.3
(2.5) 		1898.7
(2.1) 		1042

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1544
1 2 3 4 5 6 range
A 2020.1
(0.2)
P 		2191.8
(0.9)
P 		1428.3
(-2.1)
P 		1199.5
(-3)
P 		1777.3
(-0.8)
P 		2743.6
(3)
P 		1544
B 1709.9
(-0.3)
P 		2227.3
(3)
P 		1779.6
(0.2)
P 		1321.8
(-2.7)
P 		1280.4
(-3)
P 		1863.7
(0.7)
P 		947
C 2396.8
(3)
P 		1403.4
(-2.9)
P 		2045
(0.9)
P 		1668.7
(-1.3)
P 		1378.6
(-3)
P 		2093.1
(1.2)
P 		1018
avr 2042.3
(1.6) 		1940.8
(0.9) 		1751
(-0.5) 		1396.7
(-3) 		1478.8
(-2.4) 		2233.5
(3) 		837
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 436
1 2 3 4 range
A 273.8
(-1.7)
P 		415.8
(0.2)
P 		617.8
(3)
P 		182.1
(-3)
P 		436
B 364.4
(-3)
P 		542.1
(3)
P 		451.2
(-0.1)
P 		395.8
(-1.9)
P 		178
C 387.1
(-3)
P 		598.2
(3)
P 		555.8
(1.8)
P 		437.5
(-1.6)
P 		211
avr 341.8
(-2.9) 		518.7
(2.3) 		541.6
(3) 		338.5
(-3) 		203

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 584
1 2 3 4 5 6 range
A 372.4
(-2.1)
P 		779.5
(3)
P 		311
(-2.9)
P 		304.2
(-3)
P 		536.3
(-0.1)
P 		668
(1.6)
P 		475
B 595
(0.8)
P 		741.4
(3)
P 		432.1
(-1.7)
P 		350.1
(-3)
P 		520.2
(-0.4)
P 		695
(2.3)
P 		391
C 888.4
(3)
P 		428.2
(-2)
P 		520.5
(-1)
P 		335.6
(-3)
P 		446.1
(-1.8)
P 		700.7
(1)
P 		553
avr 618.6
(1.8) 		649.7
(2.4) 		421.2
(-1.5) 		330
(-3) 		500.9
(-0.1) 		687.9
(3) 		358
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191541_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14206
Sequence Type Exemplar sequence
Representative Public ID C54D10.1 NCBI
Target Description C54D10.1 /REP_DB=WormBase Gene ID /WP=CE05497 /TR=Q18831 /GB=CAA99803.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Glutathione S-transferases.
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073713(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073713 NCBI Caenorhabditis elegans CaDmium Responsive family member (cdr-2) (cdr-2) mRNA, complete cds. 11/11 None
SNAP00000038016 ENSEMBL cdna:SNAP chromosome:CEL140:V:12417272:12418292:-1 11/11 None
GENEFINDER00000038037 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:12417272:12418292:-1 11/11 None
C54D10.1 ENSEMBL cdna:known chromosome:CEL140:V:12417237:12418297:-1 gene:C54D10.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:12417271-12418292(-) 100.0 100.0
Public Domain and Genome References
Gene Title glutathione S-transferase
Gene Symbol cdr-2
Ensembl C54D10.1
Entrez Gene 183779 Entrez gene
SwissProt Q18831 EMBL-EBI
WormBase CE05497 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAU43723 cadmium-inducible lysosomal protein CDR-2 [Caenorhabditis elegans] emb|CAA99803.1| Hypothetical protein C54D10.1 [Caenorhabditis elegans] ref|NP_506114.1| CaDmium Responsive family member (cdr-2) [Caenorhabditis elegans] 1.0E-161
blast CAE75480 Hypothetical protein CBG23483 [Caenorhabditis briggsae] 1.0E-126
blast CAA99804 Hypothetical protein C54D10.2 [Caenorhabditis elegans] ref|NP_506115.2| CaDmium Responsive family member (cdr-3) [Caenorhabditis elegans] 1.0E-120
Protein Domains
Database ID Description E-Value
Pfam IPR004046 EMBL-EBI Glutathione S-transferase, C-terminal 5.7E-5
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_506114.1 1 2-21
C54D10.1 1 2-21
SNAP00000038016 1 2-21
GENEFINDER00000038037 1 2-21
Sequence
Target Sequence 
>C. ELEGANS:191541_AT
catatcgcggacactgatctcattgaaatgcggcttcgaaggcattttaatatcccatct
ctaccagctgctcaagaagcacattctgtagccttgacaagacttgcagataatcatttg
ttcaatttgcttatccgttacaaaataataggagatgaatttttccatattcttgtcaga
agcattggtattccaaaattccttcagccacttctctttccacttattcgagcctcattt
ggaaagaaagtctatcagagatcgacaggatcaattggagattttgaattaaaagaaatg
gatgatattcttcatagagatttccaaacaattcaagattatttgggagatcaaaagttt
ttgttcggagataaagttacagcggcagatgcagctgtatttggtcaaattgcgtcggtg
atttatccattccggtgcagtatcaacgatgcccttga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CATATCGCGGACACTGATCTCATTG 175 215 316 Antisense
CTCATTGAAATGCGGCTTCGAAGGC 320 227 334 Antisense
AGGCATTTTAATATCCCATCTCTAC 242 55 355 Antisense
CCATCTCTACCAGCTGCTCAAGAAG 544 271 370 Antisense
GAAGCACATTCTGTAGCCTTGACAA 278 341 391 Antisense
TTGGTATTCCAAAATTCCTTCAGCC 425 683 500 Antisense
TTCCACTTATTCGAGCCTCATTTGG 669 699 533 Antisense
GCGGCAGATGCAGCTGTATTTGGTC 81 295 697 Antisense
ATTGCGTCGGTGATTTATCCATTCC 363 7 724 Antisense
TTTATCCATTCCGGTGCAGTATCAA 633 671 737 Antisense
GGTGCAGTATCAACGATGCCCTTGA 594 499 749 Antisense
Sequence Source Affymetrix Proprietary Database