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[191535_at] protein-tyrosine phosphatase

Description T28F4.3 /REP_DB=WormBase Gene ID /WP=CE06525 /TR=Q22852 /GB=CAA96694.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster 6grp_total > 76      4grp_total > 01      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 101
1 2 3 4 range
A 6.6
(-2.9)
A 		4.5
(-3)
A 		22.8
(-1.9)
A 		104.4
(3)
A 		100
B 7.8
(-3)
A 		35.3
(3)
A 		28
(1.4)
A 		17.1
(-1)
A 		28
C 39.2
(3)
A 		4.2
(-2.8)
A 		3.1
(-3)
A 		13.3
(-1.3)
A 		36
avr 17.9
(-2.4) 		14.7
(-3) 		18
(-2.3) 		44.9
(3) 		30

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 77
1 2 3 4 5 6 range
A 10.5
(-2.5)
A 		38.7
(-0.2)
A 		4.9
(-3)
A 		46.8
(0.5)
A 		30.8
(-0.8)
A 		76.7
(3)
A 		72
B 43.7
(3)
A 		5.5
(-3)
A 		10.7
(-2.2)
A 		25.4
(0.1)
A 		20.5
(-0.6)
A 		42.2
(2.8)
A 		38
C 1.2
(-3)
A 		37.9
(-0.2)
A 		46.1
(0.5)
A 		65.5
(2)
A 		35.8
(-0.3)
A 		78.5
(3)
P 		77
avr 18.5
(-3) 		27.4
(-1.9) 		20.6
(-2.7) 		45.9
(0.5) 		29
(-1.7) 		65.8
(3) 		47
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 14
1 2 3 4 range
A 2.4
(-2.4)
A 		1
(-3)
A 		6
(-0.9)
A 		15.3
(3)
A 		14
B 2.5
(-3)
A 		8.7
(3)
A 		6.5
(0.9)
A 		3.6
(-1.9)
A 		6
C 13
(3)
A 		1.2
(-2.9)
A 		1.1
(-3)
A 		2.2
(-2.4)
A 		12
avr 6
(1.2) 		3.6
(-3) 		4.5
(-1.4) 		7
(3) 		3

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 26
1 2 3 4 5 6 range
A 1.9
(-2.7)
A 		13.8
(1.3)
A 		1.1
(-3)
A 		11.9
(0.7)
A 		9.3
(-0.2)
A 		18.7
(3)
A 		18
B 15.2
(2.8)
A 		1.8
(-3)
A 		2.6
(-2.7)
A 		6.7
(-0.9)
A 		8.3
(-0.2)
A 		15.7
(3)
A 		14
C 0.4
(-3)
A 		11.6
(-0.4)
A 		11.7
(-0.4)
A 		13.2
(-0)
A 		11.6
(-0.4)
A 		26.3
(3)
P 		26
avr 5.8
(-2.7) 		9.1
(-1.4) 		5.1
(-3) 		10.6
(-0.8) 		9.7
(-1.2) 		20.2
(3) 		15
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191535_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2391
Sequence Type Exemplar sequence
Representative Public ID T28F4.3 NCBI
Target Description T28F4.3 /REP_DB=WormBase Gene ID /WP=CE06525 /TR=Q22852 /GB=CAA96694.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059699(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059699 NCBI Caenorhabditis elegans T28F4.3 (T28F4.3) mRNA, complete cds. 11/11 None
SNAP00000023976 ENSEMBL cdna:SNAP chromosome:CEL140:I:7492304:7494168:-1 11/11 None
GENEFINDER00000023988 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:7492304:7494559:-1 11/11 None
T28F4.3 ENSEMBL cdna:known chromosome:CEL140:I:7492304:7494168:-1 gene:T28F4.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:7492234-7494099(-) 92.94 100.0
Public Domain and Genome References
Gene Title protein-tyrosine phosphatase
Ensembl T28F4.3
Entrez Gene 189059 Entrez gene
SwissProt Q22852 EMBL-EBI
WormBase CE06525 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6470 protein amino acid dephosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4721 phosphoprotein phosphatase activity inferred from electronic annotation QuickGO AmiGO
4725 protein tyrosine phosphatase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA96694 Hypothetical protein T28F4.3 [Caenorhabditis elegans] ref|NP_492100.1| T28F4.3 [Caenorhabditis elegans] 0.0
blast CAE57897 Hypothetical protein CBG00946 [Caenorhabditis briggsae] 1.0E-143
blast CAE57897 Hypothetical protein CBG00946 [Caenorhabditis briggsae] 1.0E-142
blast CAE75077 Hypothetical protein CBG22995 [Caenorhabditis briggsae] 3.0E-46
blast CAE75077 Hypothetical protein CBG22995 [Caenorhabditis briggsae] 1.0E-45
Protein Domains
Database ID Description E-Value
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 2.8E-89
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 2.8E-89
Sequence
Target Sequence 
>C. ELEGANS:191535_AT
tgaaattctgaaacgtctccgcacgatgcgccttggagcagtccagtcacaacttcaata
cgtttatctcgttgttcttatgattgaattgttcattgatgacaagattatcaagaggaa
cgcgaattacgagtcgttgctcaaaaagtatgcagatgtgacccgaaaagtgactgcggc
aattatggaagaagaagagaaacggcgacagaggaagaaaagagaagaggaaaaggaaaa
agaacaagagaaggaatcacctgcaacgaaagaagaaaagaagaaggaaaatggattgaa
gacgaatcgtcaacgagataatcgagaagctccttcaaaacctcccaggaaaaatcctga
ggaactggcacgctcgaaacttcaaggcccaagaaagctgacactgaaaaatagagatgg
aaacgcagaagagccgacagcaaaggacaatgaggaaagatcaactgcagaggataaatc
gaaaaatcgtcagaagagtgtctacgtcaaaatgccgctgtcatcaaaggagaaggg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGAAATTCTGAAACGTCTCCGCACG 193 573 861 Antisense
GTCACAACTTCAATACGTTTATCTC 230 465 906 Antisense
ACGTTTATCTCGTTGTTCTTATGAT 530 93 920 Antisense
GAACGCGAATTACGAGTCGTTGCTC 341 347 978 Antisense
GTGACCCGAAAAGTGACTGCGGCAA 291 483 1018 Antisense
TCGAGAAGCTCCTTCAAAACCTCCC 515 599 1182 Antisense
AATCCTGAGGAACTGGCACGCTCGA 575 165 1213 Antisense
CAAGGCCCAAGAAAGCTGACACTGA 611 181 1243 Antisense
GGAAACGCAGAAGAGCCGACAGCAA 533 527 1279 Antisense
GTGTCTACGTCAAAATGCCGCTGTC 696 485 1358 Antisense
TGCCGCTGTCATCAAAGGAGAAGGG 36 583 1373 Antisense
Sequence Source Affymetrix Proprietary Database