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[191497_at] 7tm receptor

Description T04A8.2 /REP_DB=WormBase Gene ID /WP=CE01071 /GEN=srg-11 /TR=SW:P46569 /GB=CAA84735.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=7tm receptor
Cluster 6grp_total > 39      4grp_total > 20      6grp_cgc > 09      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 61
1 2 3 4 range
A 21.6
(-0.9)
A 		10.8
(-3)
A 		10.9
(-3)
A 		42.1
(3)
A 		31
B 30.8
(-1.8)
P 		64.5
(3)
P 		22.1
(-3)
A 		26.1
(-2.4)
A 		42
C 41
(0)
P 		21.2
(-1.9)
A 		10.3
(-3)
A 		71.3
(3)
P 		61
avr 31.1
(0.1) 		32.2
(0.3) 		14.4
(-3) 		46.5
(3) 		32

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 36
1 2 3 4 5 6 range
A 27.6
(1.4)
A 		20.6
(0.2)
A 		5.8
(-2.4)
A 		2.1
(-3)
A 		29.4
(1.7)
A 		36.9
(3)
A 		35
B 13.6
(-2.6)
A 		18.5
(-1.4)
A 		15.6
(-2.1)
A 		37.6
(3)
P 		31.2
(1.5)
P 		11.7
(-3)
A 		26
C 28.6
(1.2)
A 		35.8
(3)
A 		12.2
(-3)
A 		22.6
(-0.4)
A 		19
(-1.3)
A 		23.8
(-0.1)
A 		24
avr 23.3
(1.7) 		25
(2.4) 		11.2
(-3) 		20.8
(0.8) 		26.5
(3) 		24.1
(2.1) 		15
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 14
1 2 3 4 range
A 7.9
(3)
A 		2.3
(-3)
A 		2.8
(-2.5)
A 		6.2
(1.2)
A 		6
B 9.8
(-0.4)
P 		15.9
(3)
P 		5.1
(-3)
A 		5.6
(-2.7)
A 		11
C 13.6
(3)
P 		6.1
(-1.5)
A 		3.6
(-3)
A 		12
(2)
P 		10
avr 10.4
(3) 		8.1
(0.9) 		3.8
(-3) 		7.9
(0.7) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 12
1 2 3 4 5 6 range
A 5.1
(0.2)
A 		7.3
(1.8)
A 		1.3
(-2.4)
A 		0.5
(-3)
A 		8.9
(2.9)
A 		9
(3)
A 		9
B 4.7
(-2.4)
A 		6.2
(-1.4)
A 		3.8
(-3)
A 		10
(1.2)
P 		12.7
(3)
P 		4.4
(-2.6)
A 		9
C 10.6
(2.8)
A 		10.9
(3)
A 		3.1
(-3)
A 		4.5
(-1.9)
A 		6.2
(-0.6)
A 		8
(0.8)
A 		8
avr 6.8
(0.7) 		8.1
(1.9) 		2.7
(-3) 		5
(-0.9) 		9.3
(3) 		7.1
(1) 		7
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191497_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8089
Sequence Type Exemplar sequence
Representative Public ID T04A8.2 NCBI
Target Description T04A8.2 /REP_DB=WormBase Gene ID /WP=CE01071 /GEN=srg-11 /TR=SW:P46569 /GB=CAA84735.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=7tm receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065554(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065554 NCBI Caenorhabditis elegans Serpentine Receptor, class G (gamma) family member (srg-11) (srg-11) mRNA, complete cds. 11/11 None
SNAP00000041090 ENSEMBL cdna:SNAP chromosome:CEL140:III:4680432:4681525:1 9/11 None
T04A8.2 ENSEMBL cdna:known chromosome:CEL140:III:4679976:4681525:1 gene:T04A8.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:4679975-4681141(+) 100.0 100.0
Public Domain and Genome References
Gene Title 7tm receptor
Gene Symbol srg-11
Ensembl T04A8.2
Entrez Gene 191837 Entrez gene
SwissProt P46569 EMBL-EBI
WormBase CE33165 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7165 signal transduction inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4888 transmembrane receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA84735 Hypothetical protein T04A8.2 [Caenorhabditis elegans] ref|NP_497955.2| Serpentine Receptor, class G (gamma) family member (srg-11) [Caenorhabditis elegans] sp|P46569|SRG11_CAEEL Serpentine receptor class gamma-11 (Protein srg-11) 1.0E-174
blast 2123261AL chemosensory receptor 1.0E-151
blast CAA84735 Hypothetical protein T04A8.2 [Caenorhabditis elegans] ref|NP_497955.2| Serpentine Receptor, class G (gamma) family member (srg-11) [Caenorhabditis elegans] sp|P46569|SRG11_CAEEL Serpentine receptor class gamma-11 (Protein srg-11) 1.0E-135
blast 2123261AL chemosensory receptor 1.0E-112
blast NP_491823 Serpentine Receptor, class G (gamma) family member (srg-14) [Caenorhabditis elegans] gb|AAB37789.1| Serpentine receptor, class g (gamma) protein 14 [Caenorhabditis elegans] sp|P91275|SRG14_CAEEL Serpentine receptor class gamma-14 (Protein srg-14) 3.0E-75
blast NP_491823 Serpentine Receptor, class G (gamma) family member (srg-14) [Caenorhabditis elegans] gb|AAB37789.1| Serpentine receptor, class g (gamma) protein 14 [Caenorhabditis elegans] sp|P91275|SRG14_CAEEL Serpentine receptor class gamma-14 (Protein srg-14) 2.0E-60
Protein Domains
Database ID Description E-Value
Pfam IPR000609 EMBL-EBI Integral membrane protein Srg, nematode type 3.1E-81
Pfam IPR000609 EMBL-EBI Integral membrane protein Srg, nematode type 2.9E-108
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_497955.2 7 32-54,61-83,98-120,156-178,204-226,239-261,271-293
T04A8.2 7 32-54,61-83,98-120,156-178,204-226,239-261,271-293
SNAP00000041090 5 10-32,77-99,125-147,160-182,192-214
Sequence
Target Sequence 
>C. ELEGANS:191497_AT
gatttacgcatcaagctctttctttttgatatattcaactgactgctttgtaagcttctc
gatgatatttttggatataattggccgtacacttgtctattttaccccattatgtcctat
cattgcaccaatgttctacgaaccattgatcggtttcaagattatgatgatagtgctaca
tcattcaagagcgtgtaaatcactaattcaaattctacttgttgtaaatcgaatgtcgtg
tgttatttatccaattcgatatggtaaaatgtggatgagaccgttgaaatatttgatcat
tttggtatttgtgataccattttcaattgattggaatcttatcatatcaagagtttatat
gcagccaacttttggggggatttatatggaatacatcaaaaaagttgcatgggcaagtca
atctcgtttccaactaattttcatcacaattgctctactcttcacaattgtctgcacatc
tgtcattttctatacacttgttatgcttcccaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GATTTACGCATCAAGCTCTTTCTTT 84 429 189 Antisense
CTGACTGCTTTGTAAGCTTCTCGAT 276 239 227 Antisense
GGATATAATTGGCCGTACACTTGTC 292 495 261 Antisense
TACACTTGTCTATTTTACCCCATTA 174 643 276 Antisense
TACCCCATTATGTCCTATCATTGCA 674 647 291 Antisense
CATTGCACCAATGTTCTACGAACCA 12 217 309 Antisense
GAATGTCGTGTGTTATTTATCCAAT 137 333 419 Antisense
GCATGGGCAAGTCAATCTCGTTTCC 389 309 595 Antisense
TGCTCTACTCTTCACAATTGTCTGC 510 581 639 Antisense
ATTGTCTGCACATCTGTCATTTTCT 335 5 655 Antisense
TCTATACACTTGTTATGCTTCCCAA 444 615 677 Antisense
Sequence Source Affymetrix Proprietary Database