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[191488_at] 7TM receptor, srx family

Description R10D12.4 /REP_DB=WormBase Gene ID /WP=CE12678 /TR=Q9XVK3 /GB=CAB03242.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=G-protein coupled receptor
Cluster 6grp_total > 83      4grp_total > 01      6grp_cgc > 87      6grp_cgc_sub > 05      6grp_total_sub > Hat      6grp_rule_based > S5      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 67
1 2 3 4 range
A 5.5
(-3)
A 		18.8
(-1.7)
A 		35.5
(-0.2)
A 		68.8
(3)
A 		63
B 16.5
(3)
A 		2.1
(-3)
A 		2.5
(-2.8)
A 		3.9
(-2.3)
A 		14
C 10.1
(-2.1)
A 		6.3
(-2.5)
A 		2.5
(-3)
A 		52.9
(3)
A 		50
avr 10.7
(-2.7) 		9.1
(-3) 		13.5
(-2.2) 		41.9
(3) 		33

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 38
1 2 3 4 5 6 range
A 2.8
(-3)
A 		2.8
(-3)
A 		14.7
(-0.9)
A 		23.5
(0.6)
A 		36.9
(3)
A 		3.3
(-2.9)
A 		34
B 1.3
(-3)
A 		2.3
(-2.8)
A 		26.4
(1)
A 		11.8
(-1.3)
A 		39.3
(3)
P 		16.1
(-0.7)
A 		38
C 4.1
(-3)
A 		17.2
(0.5)
A 		6.8
(-2.3)
A 		25.4
(2.7)
A 		26.4
(3)
A 		10.9
(-1.2)
A 		22
avr 2.7
(-3) 		7.4
(-2.1) 		16
(-0.5) 		20.2
(0.3) 		34.2
(3) 		10.1
(-1.6) 		32
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 10
1 2 3 4 range
A 2
(-3)
A 		4.1
(-1.4)
A 		9.3
(2.4)
A 		10.1
(3)
A 		8
B 5.3
(3)
A 		0.5
(-3)
A 		0.6
(-2.9)
A 		0.8
(-2.6)
A 		5
C 3.4
(-1.1)
A 		1.8
(-2.3)
A 		0.9
(-3)
A 		8.9
(3)
A 		8
avr 3.6
(-1) 		2.1
(-3) 		3.6
(-1) 		6.6
(3) 		5

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 16
1 2 3 4 5 6 range
A 0.5
(-3)
A 		1
(-2.7)
A 		3.2
(-1.5)
A 		6
(0.1)
A 		11.1
(3)
A 		0.8
(-2.8)
A 		11
B 0.4
(-3)
A 		0.8
(-2.8)
A 		6.4
(-0.7)
A 		3.1
(-2)
A 		16
(3)
P 		6
(-0.8)
A 		16
C 1.5
(-3)
A 		5.3
(0.3)
A 		1.7
(-2.8)
A 		5.1
(0.1)
A 		8.5
(3)
A 		3.6
(-1.2)
A 		7
avr 0.8
(-3) 		2.4
(-2.1) 		3.8
(-1.4) 		4.7
(-0.9) 		11.9
(3) 		3.5
(-1.5) 		11
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191488_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14769
Sequence Type Exemplar sequence
Representative Public ID R10D12.4 NCBI
Target Description R10D12.4 /REP_DB=WormBase Gene ID /WP=CE12678 /TR=Q9XVK3 /GB=CAB03242.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=G-protein coupled receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074058(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074058 NCBI Caenorhabditis elegans Serpentine Receptor, class X family member (srx-10) (srx-10) mRNA, complete cds. 11/11 None
GENEFINDER00000021074 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:13947837:13949011:-1 11/11 None
R10D12.4 ENSEMBL cdna:known chromosome:CEL140:V:13947967:13949074:-1 gene:R10D12.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:13947966-13949011(-) 100.0 100.0
Public Domain and Genome References
Gene Title 7TM receptor, srx family
Gene Symbol srx-10
Ensembl R10D12.4
Entrez Gene 187761 Entrez gene
SwissProt Q9XVK3 EMBL-EBI
WormBase CE36316 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAB03242 Hypothetical protein R10D12.4 [Caenorhabditis elegans] ref|NP_506459.2| Serpentine Receptor, class X family member (srx-10) [Caenorhabditis elegans] 1.0E-149
blast CAB03242 Hypothetical protein R10D12.4 [Caenorhabditis elegans] ref|NP_506459.2| Serpentine Receptor, class X family member (srx-10) [Caenorhabditis elegans] 1.0E-131
blast CAE66189 Hypothetical protein CBG11427 [Caenorhabditis briggsae] 2.0E-66
blast CAE66189 Hypothetical protein CBG11427 [Caenorhabditis briggsae] 7.0E-61
blast AAG24152 Serpentine receptor, class x protein 1 [Caenorhabditis elegans] ref|NP_505328.2| Serpentine Receptor, class X family member (srx-1) [Caenorhabditis elegans] 2.0E-28
blast AAG24152 Serpentine receptor, class x protein 1 [Caenorhabditis elegans] ref|NP_505328.2| Serpentine Receptor, class X family member (srx-1) [Caenorhabditis elegans] 5.0E-25
Protein Domains
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_506459.2 7 5-27,40-62,89-111,124-146,174-196,223-242,257-279
R10D12.4 7 5-27,40-62,89-111,124-146,174-196,223-242,257-279
GENEFINDER00000021074 6 20-42,62-84,103-125,153-175,202-221,236-258
Sequence
Target Sequence 
>C. ELEGANS:191488_AT
atatcgcatttcagttggtacaacaccattttcgtaatgattgtaatggcattaaatcga
atgacactagttgttttaaacaaacctaacatcttcacaaaacagcgtgttctaacctac
tttttcatttcttcaattttatctttttccaaagtggttttcgatgtcttcctgattcca
tgctgtttggtgcttatggatcataaaaaatatggatggacttattacaatccaaaaaat
ataaaaaattggggagaattaattgacacaattatggaagttggaatttttacagcgaca
ctcttatgctatgttataattttcataaaaatccgaatttcaaataactctgtggaacag
tcaattgactcaaaacattttcaaaaacttcgtgctcgagaacgatcggttgcggtacaa
ttcgctttggtttcaattttctcaattatcagttttgcgtcattcaaagtggttccaatg
atttttggtaaactgaatactgaaagtaatattatcagtccaatttgttttgctgttcac
tgttgtgccaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATATCGCATTTCAGTTGGTACAACA 641 7 211 Antisense
TAAACAAACCTAACATCTTCACAAA 101 639 287 Antisense
CAAAACAGCGTGTTCTAACCTACTT 656 189 308 Antisense
TAACCTACTTTTTCATTTCTTCAAT 151 639 323 Antisense
AGTGGTTTTCGATGTCTTCCTGATT 363 59 363 Antisense
GATTCCATGCTGTTTGGTGCTTATG 579 433 384 Antisense
ACAGCGACACTCTTATGCTATGTTA 250 109 502 Antisense
GTGCTCGAGAACGATCGGTTGCGGT 204 479 602 Antisense
GCGGTACAATTCGCTTTGGTTTCAA 70 241 622 Antisense
TCAATTATCAGTTTTGCGTCATTCA 543 633 652 Antisense
GTTTTGCTGTTCACTGTTGTGCCAA 117 449 737 Antisense
Sequence Source Affymetrix Proprietary Database