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[191425_at] 7TM chemoreceptor, srh family

Description F37B4.6 /REP_DB=WormBase Gene ID /WP=CE24958 /GEN=srh-241 /TR=O45164 /GB=AAK18949.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=chemoreceptor
Cluster 6grp_total > 18      4grp_total > 12      6grp_cgc > 03      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 124
1 2 3 4 range
A 49.8
(-2)
A 		67.9
(-0.7)
A 		37
(-3)
A 		117.8
(3)
P 		81
B 45.7
(0.6)
A 		38
(-0.3)
A 		13.3
(-3)
A 		67.4
(3)
P 		54
C 72
(-0.7)
A 		31.2
(-3)
A 		35.6
(-2.8)
A 		137
(3)
P 		106
avr 55.8
(-0.9) 		45.7
(-1.7) 		28.6
(-3) 		107.4
(3) 		79

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 78
1 2 3 4 5 6 range
A 83.9
(3)
A 		24.1
(-1.6)
A 		36.7
(-0.6)
A 		44
(-0.1)
A 		5.8
(-3)
A 		55.9
(0.8)
A 		78
B 51.5
(1.6)
A 		65.5
(3)
A 		5.8
(-3)
A 		24.3
(-1.1)
A 		50.2
(1.5)
A 		22.6
(-1.3)
A 		60
C 16.7
(-3)
A 		51
(1)
A 		42.6
(0)
A 		57.5
(1.8)
A 		67.8
(3)
A 		31.1
(-1.3)
A 		51
avr 50.7
(3) 		46.9
(2) 		28.4
(-3) 		41.9
(0.6) 		41.3
(0.5) 		36.5
(-0.8) 		22
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 21
1 2 3 4 range
A 18.1
(3)
A 		14.7
(0.6)
A 		9.7
(-3)
A 		17.2
(2.4)
P 		8
B 14.6
(3)
A 		9.4
(0.3)
A 		3.1
(-3)
A 		14.4
(2.9)
P 		12
C 23.8
(3)
A 		9
(-3)
A 		12.4
(-1.6)
A 		23.1
(2.7)
P 		15
avr 18.8
(3) 		11
(-1.5) 		8.4
(-3) 		18.2
(2.7) 		10

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 21
1 2 3 4 5 6 range
A 15.5
(3)
A 		8.6
(-0)
A 		8
(-0.3)
A 		11.2
(1.1)
A 		1.8
(-3)
A 		13.6
(2.2)
A 		14
B 17.9
(1.9)
A 		21.8
(3)
A 		1.4
(-3)
A 		6.4
(-1.5)
A 		20.4
(2.6)
A 		8.4
(-0.9)
A 		20
C 6.2
(-3)
A 		15.6
(0.6)
A 		10.8
(-1.2)
A 		11.6
(-0.9)
A 		21.9
(3)
A 		10.4
(-1.4)
A 		16
avr 13.2
(1.5) 		15.3
(3) 		6.7
(-3) 		9.7
(-0.9) 		14.7
(2.6) 		10.8
(-0.1) 		9
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191425_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.15306
Sequence Type Exemplar sequence
Representative Public ID F37B4.6 NCBI
Target Description F37B4.6 /REP_DB=WormBase Gene ID /WP=CE24958 /GEN=srh-241 /TR=O45164 /GB=AAK18949.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=chemoreceptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_071377(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_071377 NCBI Caenorhabditis elegans Serpentine Receptor, class H family member (srh-241) (srh-241) mRNA, complete cds. 11/11 None
SNAP00000026930 ENSEMBL cdna:SNAP chromosome:CEL140:V:2867698:2869277:-1 9/11 None
GENEFINDER00000026936 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:2858689:2869430:-1 11/11 None
F37B4.6 ENSEMBL cdna:known chromosome:CEL140:V:2867619:2869430:-1 gene:F37B4.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:2867618-2869430(-) 100.0 100.0
Public Domain and Genome References
Gene Title 7TM chemoreceptor, srh family
Gene Symbol srh-241
Ensembl F37B4.6
Entrez Gene 191890 Entrez gene
SwissProt O45164 EMBL-EBI
WormBase CE24958 Wormbase
Functional Annotations
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4867 serine-type endopeptidase inhibitor activity inferred from electronic annotation QuickGO AmiGO
4930 G-protein coupled receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK18949 Serpentine receptor, class h protein 241 [Caenorhabditis elegans] ref|NP_503778.1| Serpentine Receptor, class H family member (srh-241) [Caenorhabditis elegans] 0.0
blast G88979 protein F37B4.5 [imported] - Caenorhabditis elegans 0.0
blast G88978 protein F37B4.6 [imported] - Caenorhabditis elegans 1.0E-134
blast G88978 protein F37B4.6 [imported] - Caenorhabditis elegans 1.0E-133
blast AAK18946 Serpentine receptor, class h protein 243 [Caenorhabditis elegans] ref|NP_503779.1| Serpentine Receptor, class H family member (srh-243) [Caenorhabditis elegans] 7.0E-81
blast AAK18949 Serpentine receptor, class h protein 241 [Caenorhabditis elegans] ref|NP_503778.1| Serpentine Receptor, class H family member (srh-241) [Caenorhabditis elegans] 8.0E-77
Protein Domains
Database ID Description E-Value
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 1.0E-126
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 4.1E-80
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 4.1E-87
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 4.3E-11
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_503778.1 7 20-42,62-84,99-119,140-157,202-224,245-267,277-299
F37B4.6 7 20-42,62-84,99-119,140-157,202-224,245-267,277-299
SNAP00000026930 4 9-31,46-68,89-106,135-157
GENEFINDER00000026936 15 20-42,62-84,99-119,140-157,202-224,245-267,277-299,411-430,467-489,520-542,546-568,580-602,617-639,684-706,734-756
Sequence
Target Sequence 
>C. ELEGANS:191425_AT
tacactctagtacctctcatatttctacctccctattttgatctcccggaacaggaaagt
gctcgtcagctggtgttgagcaaaatcccgtgccaacctccatttgattttaagcatcgg
gaaatttacgtcctggctctggattatgatgttcccgtctattgcattgcatttgggaca
ttggtgttaggtgtctcaataactgttttcggctggctgatttttcatatgttgtggttt
ggcacactgagctcaagtaactctataagaactttgaatatgcaacgcagatttgcaatt
tcactaactatacagtcaacttttatgatttcggtggtacttaccccggtattgacaatc
ctatggatcatcttcaaatggtaccacaaccaaatgttgaacaattttatttttatcaca
ttatcccttcacggagttggatctactattgtcatgatatgtgttcacaggccgtatcga
gagttcactttct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TACACTCTAGTACCTCTCATATTTC 433 643 445 Antisense
TCCCTATTTTGATCTCCCGGAACAG 132 599 474 Antisense
GGAAAGTGCTCGTCAGCTGGTGTTG 444 527 498 Antisense
GGTGTTGAGCAAAATCCCGTGCCAA 109 499 516 Antisense
CGTGCCAACCTCCATTTGATTTTAA 708 245 533 Antisense
GAAATTTACGTCCTGGCTCTGGATT 271 363 565 Antisense
GATTATGATGTTCCCGTCTATTGCA 50 431 586 Antisense
ACTGTTTTCGGCTGGCTGATTTTTC 302 97 646 Antisense
TGGTTTGGCACACTGAGCTCAAGTA 592 549 679 Antisense
TTTTATCACATTATCCCTTCACGGA 498 675 855 Antisense
AGGCCGTATCGAGAGTTCACTTTCT 490 51 913 Antisense
Sequence Source Affymetrix Proprietary Database