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[191369_at] aspartate aminotransferase

Description C14E2.2 /REP_DB=WormBase Gene ID /WP=CE06829 /TR=Q17983 /GB=AAA85747.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=aspartate aminotransferase
Cluster 6grp_total > 55      4grp_total > 28      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 89
1 2 3 4 range
A 87.8
(-0.6)
A 		70.6
(-3)
A 		85.9
(-0.9)
A 		114.3
(3)
A 		44
B 98.8
(-0.3)
A 		129.8
(3)
A 		72.6
(-3)
A 		83.2
(-1.9)
A 		57
C 90.8
(-0.2)
A 		92.4
(-0.1)
A 		49.5
(-3)
A 		138.3
(3)
A 		89
avr 92.5
(0.3) 		97.6
(1) 		69.3
(-3) 		111.9
(3) 		43

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 106
1 2 3 4 5 6 range
A 51.3
(-0.3)
A 		59.9
(0.5)
A 		70.8
(1.5)
A 		86.4
(3)
A 		23.1
(-3)
A 		84.7
(2.8)
A 		63
B 10.1
(-3)
A 		92.6
(2)
A 		108.6
(3)
A 		64.5
(0.3)
A 		59.4
(0)
A 		93.9
(2.1)
A 		99
C 55.3
(-1.6)
A 		116
(3)
A 		36.7
(-3)
A 		60.8
(-1.2)
A 		60
(-1.2)
A 		92.8
(1.2)
A 		79
avr 38.9
(-3) 		89.5
(2.9) 		72
(0.8) 		70.6
(0.7) 		47.5
(-2) 		90.5
(3) 		52
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 17
1 2 3 4 range
A 32
(3)
A 		15.3
(-3)
A 		22.5
(-0.4)
A 		16.7
(-2.5)
A 		17
B 31.5
(2.8)
A 		32.1
(3)
A 		16.8
(-3)
A 		17.7
(-2.6)
A 		15
C 30
(3)
A 		26.6
(1.4)
A 		17.2
(-3)
A 		23.3
(-0.1)
A 		13
avr 31.2
(3) 		24.7
(-0.1) 		18.8
(-3) 		19.2
(-2.8) 		12

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 32
1 2 3 4 5 6 range
A 9.5
(-2)
A 		21.3
(2.8)
A 		15.4
(0.4)
A 		21.9
(3)
A 		7
(-3)
A 		20.6
(2.5)
A 		15
B 3.5
(-3)
A 		30.8
(2.2)
A 		26.4
(1.4)
A 		17.1
(-0.4)
A 		24.1
(0.9)
A 		35
(3)
A 		32
C 20.5
(-0.4)
A 		35.4
(3)
A 		9.3
(-3)
A 		12.2
(-2.3)
A 		19.4
(-0.7)
A 		31.1
(2)
A 		26
avr 11.2
(-3) 		29.2
(3) 		17
(-1.1) 		17.1
(-1) 		16.8
(-1.1) 		28.9
(2.9) 		18
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191369_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18100
Sequence Type Exemplar sequence
Representative Public ID C14E2.2 NCBI
Target Description C14E2.2 /REP_DB=WormBase Gene ID /WP=CE06829 /TR=Q17983 /GB=AAA85747.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=aspartate aminotransferase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_075930(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_075930 NCBI Caenorhabditis elegans C14E2.2 (C14E2.2) mRNA, complete cds. 11/11 None
SNAP00000021823 ENSEMBL cdna:SNAP chromosome:CEL140:X:1806827:1809537:-1 11/11 None
GENEFINDER00000021837 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:1806827:1809537:-1 11/11 None
C14E2.2 ENSEMBL cdna:known chromosome:CEL140:X:1806827:1809537:-1 gene:C14E2.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:1806826-1809537(-) 100.0 100.0
Public Domain and Genome References
Gene Title aspartate aminotransferase
Ensembl C14E2.2
Entrez Gene 182614 Entrez gene
SwissProt Q17983 EMBL-EBI
WormBase CE06829 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6520 amino acid metabolism inferred from electronic annotation QuickGO AmiGO
9058 biosynthesis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8483 transaminase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA85747 Hypothetical protein C14E2.2 [Caenorhabditis elegans] ref|NP_508331.1| C14E2.2 [Caenorhabditis elegans] 0.0
blast AAA85747 Hypothetical protein C14E2.2 [Caenorhabditis elegans] ref|NP_508331.1| C14E2.2 [Caenorhabditis elegans] 1.0E-150
blast AAB00578 Hypothetical protein T01C8.5 [Caenorhabditis elegans] ref|NP_510709.1| T01C8.5 [Caenorhabditis elegans] sp|Q22067|AATC_CAEEL Probable aspartate aminotransferase, cytoplasmic (Transaminase A) (Glutamate oxaloacetate transaminase-1) 1.0E-104
blast AAB00578 Hypothetical protein T01C8.5 [Caenorhabditis elegans] ref|NP_510709.1| T01C8.5 [Caenorhabditis elegans] sp|Q22067|AATC_CAEEL Probable aspartate aminotransferase, cytoplasmic (Transaminase A) (Glutamate oxaloacetate transaminase-1) 1.0E-103
blast CAE69898 Hypothetical protein CBG16248 [Caenorhabditis briggsae] 1.0E-102
Protein Families
Method ID Description E-Value
ec AATM_HUMAN (P00505) Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase-2) 1.0E-136
ec AATC_HUMAN (P17174) Aspartate aminotransferase, cytoplasmic (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase-1) 1.0E-131
Protein Domains
Database ID Description E-Value
Pfam IPR004839 EMBL-EBI Aminotransferase, class I and II 1.2E-49
Pfam IPR004839 EMBL-EBI Aminotransferase, class I and II 1.2E-49
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000021837 1 117-139
Sequence
Target Sequence 
>C. ELEGANS:191369_AT
aattgtttgtggctcagtcgttcgctaaaaacttattttttacgaatccgcggttgggaa
atcttacagttgtcgtaaacaacgctgccgtcattcctggaataaaatctcagatgtcgc
ttgctatccgcattaacgcgttttatccaacagcatttggagctacaattgtacacaagg
tcctctccacctcagctcgtcgtgaattttggattcagtctattcaacagatatcttctc
gcatcaagcaaatgagaactgctttgtttgacgttttgagtgctctcaaaactccaggaa
gctgggatcatatcattcgacaaactggaatgtttagctacactggtctcacttctactc
aagtcgatcacctcgttcgcaaccacaaagtcttcctcctcagcgacggacgcataaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AATTGTTTGTGGCTCAGTCGTTCGC 91 179 605 Antisense
TTGTCGTAAACAACGCTGCCGTCAT 618 707 674 Antisense
AAATCTCAGATGTCGCTTGCTATCC 76 119 709 Antisense
GCTTGCTATCCGCATTAACGCGTTT 583 305 723 Antisense
CAATTGTACACAAGGTCCTCTCCAC 654 179 770 Antisense
CACCTCAGCTCGTCGTGAATTTTGG 238 201 792 Antisense
CAACAGATATCTTCTCGCATCAAGC 327 187 829 Antisense
AGTGCTCTCAAAACTCCAGGAAGCT 578 59 883 Antisense
ATGTTTAGCTACACTGGTCTCACTT 613 47 934 Antisense
GTCTCACTTCTACTCAAGTCGATCA 658 469 950 Antisense
TCCTCCTCAGCGACGGACGCATAAA 328 593 998 Antisense
Sequence Source Affymetrix Proprietary Database