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[191364_at] Glutathione peroxidases

Description R05H10.5 /REP_DB=WormBase Gene ID /WP=CE18107 /TR=SW:O62327 /GB=CAB05581.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=Glutathione peroxidases
Cluster 6grp_high1_10_10 > 47      4grp_highest_8_8 > 32      4grp_high_8_8 > 43      6grp_total > 46      4grp_total > 52      6grp_high1_sub > Cu      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 173
1 2 3 4 range
A 226.7
(0.3)
P 		250.1
(1.4)
P 		284.8
(3)
P 		153.5
(-3)
P 		131
B 262.4
(3)
P 		230.1
(0.6)
P 		215.6
(-0.5)
P 		182.1
(-3)
P 		80
C 272.9
(0.3)
P 		326.2
(3)
P 		208
(-3)
P 		207.9
(-3)
P 		118
avr 254
(2) 		268.8
(3) 		236.1
(0.8) 		181.2
(-3) 		88

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 232
1 2 3 4 5 6 range
A 213.2
(3)
P 		162.8
(0.3)
P 		149.3
(-0.4)
P 		101
(-3)
A 		123.9
(-1.8)
P 		123.3
(-1.8)
P 		112
B 139.9
(-1)
P 		190
(1)
P 		165.8
(0)
P 		147
(-0.7)
P 		89.5
(-3)
P 		241.7
(3)
P 		152
C 295.7
(3)
P 		129.8
(-1.3)
P 		189.2
(0.2)
P 		63.5
(-3)
A 		116.3
(-1.6)
P 		274
(2.4)
P 		232
avr 216.3
(3) 		160.9
(0) 		168.1
(0.4) 		103.8
(-3) 		109.9
(-2.7) 		213
(2.8) 		113
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 71
1 2 3 4 range
A 82.5
(3)
P 		54.3
(0.2)
P 		74.5
(2.2)
P 		22.5
(-3)
P 		60
B 83.7
(3)
P 		56.8
(-0.6)
P 		50
(-1.5)
P 		38.8
(-3)
P 		45
C 90.3
(2.6)
P 		93.8
(3)
P 		72.5
(0.8)
P 		35
(-3)
P 		59
avr 85.5
(3) 		68.3
(1.1) 		65.7
(0.8) 		32.1
(-3) 		53

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 97
1 2 3 4 5 6 range
A 39.3
(-0.5)
P 		57.9
(3)
P 		32.5
(-1.7)
P 		25.6
(-3)
A 		37.4
(-0.8)
P 		30
(-2.2)
P 		32
B 48.7
(-1.6)
P 		63.2
(-0)
P 		40.3
(-2.6)
P 		38.9
(-2.7)
P 		36.4
(-3)
P 		90.1
(3)
P 		54
C 109.6
(3)
P 		39.6
(-1.3)
P 		48.2
(-0.8)
P 		12.8
(-3)
A 		37.6
(-1.5)
P 		91.7
(1.9)
P 		97
avr 65.9
(2.4) 		53.6
(0.7) 		40.3
(-1.1) 		25.8
(-3) 		37.1
(-1.5) 		70.6
(3) 		45
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191364_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2831
Sequence Type Exemplar sequence
Representative Public ID R05H10.5 NCBI
Target Description R05H10.5 /REP_DB=WormBase Gene ID /WP=CE18107 /TR=SW:O62327 /GB=CAB05581.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=Glutathione peroxidases
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064677(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064677 NCBI Caenorhabditis elegans R05H10.5 (R05H10.5) mRNA, complete cds. 11/11 None
SNAP00000021681 ENSEMBL cdna:SNAP chromosome:CEL140:II:14857151:14868918:1 11/11 None
GENEFINDER00000021684 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:14855426:14868918:1 11/11 None
R05H10.5 ENSEMBL cdna:known chromosome:CEL140:II:14867565:14869045:1 gene:R05H10.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:14867561-14868915(+) 100.0 100.0
Public Domain and Genome References
Gene Title Glutathione peroxidases
Ensembl R05H10.5
Entrez Gene 187630 Entrez gene
SwissProt O62327 EMBL-EBI
WormBase CE18107 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:16058_S_AT glutathione peroxidase, putative at
ATGENOME1:13259_S_AT glutathione peroxidase, putative at
ATH1-121501:263426_AT glutathione peroxidase, putative at
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6979 response to oxidative stress inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4602 glutathione peroxidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB05579 Hypothetical protein R05H10.2 [Caenorhabditis elegans] ref|NP_497077.2| R05H10.2 [Caenorhabditis elegans] 0.0
blast CAE73435 Hypothetical protein CBG20878 [Caenorhabditis briggsae] 1.0E-165
blast CAE73435 Hypothetical protein CBG20878 [Caenorhabditis briggsae] 1.0E-126
blast CAB05581 Hypothetical protein R05H10.5 [Caenorhabditis elegans] ref|NP_497078.1| R05H10.5 [Caenorhabditis elegans] sp|O62327|GPX2_CAEEL Probable glutathione peroxidase R05H10.5 1.0E-90
blast CAE17866 Hypothetical protein R05H10.7 [Caenorhabditis elegans] ref|NP_001022271.1| R05H10.7 [Caenorhabditis elegans] 8.0E-90
blast CAB05581 Hypothetical protein R05H10.5 [Caenorhabditis elegans] ref|NP_497078.1| R05H10.5 [Caenorhabditis elegans] sp|O62327|GPX2_CAEEL Probable glutathione peroxidase R05H10.5 2.0E-89
blast CAE73436 Hypothetical protein CBG20879 [Caenorhabditis briggsae] 4.0E-87
Protein Domains
Database ID Description E-Value
Pfam IPR000889 EMBL-EBI Glutathione peroxidase 5.2E-52
Pfam IPR000504 EMBL-EBI RNA-binding region RNP-1 (RNA recognition motif) 6.0E-10
Pfam IPR000504 EMBL-EBI RNA-binding region RNP-1 (RNA recognition motif) 1.7E-13
Pfam IPR000889 EMBL-EBI Glutathione peroxidase 5.2E-52
Pfam IPR000504 EMBL-EBI RNA-binding region RNP-1 (RNA recognition motif) 6.0E-10
Pfam IPR000504 EMBL-EBI RNA-binding region RNP-1 (RNA recognition motif) 1.7E-13
Pfam IPR000889 EMBL-EBI Glutathione peroxidase 5.2E-52
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000021684 2 162-184,196-218
Sequence
Target Sequence 
>C. ELEGANS:191364_AT
aaggagaagacactccactctccaactaccaaggaaaagttctaatcattgtcaacgtcg
cttcacagtgcggactcaccaattccaactacaaccagttcaaggagctcctcgatgtgt
acaaaaaagacggactcgaagttctcgcattcccgtgcaatcaattcggtggtcaggaac
catcatgcgagatcgatatcgccgcgttcgtcgccgacaaattcaaattcgagccaaccc
tgttccaaaaaatcgacgtaaacggagacaacactgctccactgtacaagttcttgaaac
aggagaagggcggatttttggtcgacgcgattaagtggaacttcacgaaattcctcgttg
gcagagatggtcacgttatcaagagattctcaccgactactgagcc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAGGAGAAGACACTCCACTCTCCAA 345 161 50 Antisense
AATCATTGTCAACGTCGCTTCACAG 210 171 93 Antisense
TTCACAGTGCGGACTCACCAATTCC 341 687 111 Antisense
TACAACCAGTTCAAGGAGCTCCTCG 431 641 139 Antisense
AGACGGACTCGAAGTTCTCGCATTC 452 71 177 Antisense
ATGCGAGATCGATATCGCCGCGTTC 192 37 234 Antisense
AATTCAAATTCGAGCCAACCCTGTT 648 161 269 Antisense
AACACTGCTCCACTGTACAAGTTCT 276 135 319 Antisense
AGGGCGGATTTTTGGTCGACGCGAT 430 57 356 Antisense
GAACTTCACGAAATTCCTCGTTGGC 291 351 387 Antisense
AGAGATTCTCACCGACTACTGAGCC 354 67 431 Antisense
Sequence Source Affymetrix Proprietary Database