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[191361_at] potassium channel protein

Description C52B11.2 /REP_DB=WormBase Gene ID /WP=CE04258 /TR=Q18776 /GB=AAA82468.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=potassium channel protein
Cluster 6grp_total > 19      4grp_total > 54      6grp_cgc > 01      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 97
1 2 3 4 range
A 119.3
(3)
A 		87.6
(0.5)
A 		42
(-3)
A 		72.3
(-0.6)
A 		77
B 139.1
(3)
A 		100.1
(-3)
A 		124.1
(0.7)
A 		101.3
(-2.8)
A 		39
C 103.8
(1.2)
A 		97.4
(0.6)
A 		125.9
(3)
A 		54.1
(-3)
A 		72
avr 120.7
(3) 		95
(-0.4) 		97.3
(-0.1) 		75.9
(-3) 		45

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 239
1 2 3 4 5 6 range
A 152.9
(3)
A 		147.1
(2.5)
A 		103.2
(-1.5)
A 		85.9
(-3)
A 		140.2
(1.9)
A 		104.6
(-1.3)
A 		67
B 166.6
(3)
A 		96
(-1.2)
A 		97.1
(-1.1)
A 		116.3
(0)
A 		99.9
(-0.9)
A 		64.9
(-3)
A 		102
C 261.8
(3)
A 		77.1
(-1.6)
A 		22.7
(-3)
A 		112.5
(-0.7)
A 		159.7
(0.4)
A 		96.7
(-1.1)
A 		239
avr 193.8
(3) 		106.7
(-1.4) 		74.3
(-3) 		104.9
(-1.5) 		133.3
(-0) 		88.7
(-2.3) 		120
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 35
1 2 3 4 range
A 43.4
(3)
A 		19
(-1.5)
A 		11
(-2.9)
A 		10.6
(-3)
A 		33
B 44.4
(3)
A 		24.7
(-2.2)
A 		28.8
(-1.1)
A 		21.6
(-3)
A 		23
C 34.4
(1.4)
A 		28
(0.3)
A 		43.9
(3)
A 		9.1
(-3)
A 		35
avr 40.7
(3) 		23.9
(-0.7) 		27.9
(0.1) 		13.8
(-3) 		27

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 91
1 2 3 4 5 6 range
A 28.2
(-1.7)
A 		52.3
(3)
A 		22.5
(-2.9)
A 		21.8
(-3)
A 		42.3
(1)
A 		25.5
(-2.3)
A 		31
B 58
(3)
A 		31.9
(-1.6)
A 		23.6
(-3)
A 		30.8
(-1.7)
A 		40.6
(-0)
A 		24.2
(-2.9)
A 		34
C 97
(3)
A 		23.5
(-1.8)
A 		5.8
(-3)
A 		22.6
(-1.9)
A 		51.7
(0)
A 		32.4
(-1.3)
A 		91
avr 61.1
(3) 		35.9
(-0.5) 		17.3
(-3) 		25.1
(-1.9) 		44.9
(0.8) 		27.4
(-1.6) 		44
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191361_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18118
Sequence Type Exemplar sequence
Representative Public ID C52B11.2 NCBI
Target Description C52B11.2 /REP_DB=WormBase Gene ID /WP=CE04258 /TR=Q18776 /GB=AAA82468.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=potassium channel protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_075838(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_075838 NCBI Caenorhabditis elegans Temporarily Assigned Gene name family member (tag-303) (tag-303) mRNA, complete cds. 11/11 None
GENEFINDER00000006105 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:1294888:1309365:1 11/11 None
C52B11.2 ENSEMBL cdna:known chromosome:CEL140:X:1300144:1308130:1 gene:C52B11.2 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000006102 2/11 Cross Hyb Matching Probes None
SNAP00000006103 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:1304579-1308130(+) 100.0 100.0
Public Domain and Genome References
Gene Title potassium channel protein
Gene Symbol tag-303
Ensembl C52B11.2
Entrez Gene 180473 Entrez gene
SwissProt Q18776 EMBL-EBI
WormBase CE04258 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.18916.1.S1_AT similar to Potassium channel tetramerisation domain containing protein 5 cfa
CANINE_2:CFAAFFX.29572.1.S1_S_AT similar to Potassium channel tetramerisation domain containing protein 5 cfa
DROSOPHILA_2:1629216_AT dm
DROSOPHILA_2:1625211_S_AT dm
DROSGENOME1:142918_AT dm
DROSGENOME1:142917_AT dm
CHICKEN:GGAAFFX.3985.1.S1_AT similar to Potassium channel tetramerisation domain containing 5 gga
HG-U133_PLUS_2:218474_S_AT potassium channel tetramerisation domain containing 5 hs
HG-U133A:218474_S_AT potassium channel tetramerisation domain containing 5 hs
HG-U133A_2:218474_S_AT potassium channel tetramerisation domain containing 5 hs
HU35KSUBB:RC_H56493_S_AT potassium channel tetramerisation domain containing 5 hs
HU35KSUBC:RC_AA429470_AT potassium channel tetramerisation domain containing 5 hs
U133_X3P:G9506650_3P_A_AT potassium channel tetramerisation domain containing 5 hs
U133_X3P:HS.61960.0.A1_3P_A_AT potassium channel tetramerisation domain containing 5 hs
HG-U133_PLUS_2:222645_S_AT potassium channel tetramerisation domain containing 5 hs
HG-U133B:222645_S_AT potassium channel tetramerisation domain containing 5 hs
HG-U95C:50160_AT potassium channel tetramerisation domain containing 5 hs
HG-U95B:56943_AT potassium channel tetramerisation domain containing 5 hs
HG-U133_PLUS_2:229837_S_AT Potassium channel tetramerisation domain containing 5 hs
HG-U133B:229837_S_AT Potassium channel tetramerisation domain containing 5 hs
HG-U95E:92103_S_AT Potassium channel tetramerisation domain containing 5 hs
HU35KSUBA:AA013042_AT Potassium channel tetramerisation domain containing 5 hs
U133_X3P:HS.61960.2.A1_3P_AT Potassium channel tetramerisation domain containing 5 hs
MG-U74BV2:108081_AT potassium channel tetramerisation domain containing 5 mm
MG-U74BV2:108080_AT potassium channel tetramerisation domain containing 5 mm
MOE430A:1423936_AT potassium channel tetramerisation domain containing 5 mm
MOUSE430A_2:1423936_AT potassium channel tetramerisation domain containing 5 mm
MOUSE430_2:1423936_AT potassium channel tetramerisation domain containing 5 mm
MOE430A:1423937_AT potassium channel tetramerisation domain containing 5 mm
MOUSE430A_2:1423937_AT potassium channel tetramerisation domain containing 5 mm
MOUSE430_2:1423937_AT potassium channel tetramerisation domain containing 5 mm
MU19KSUBA:TC19987_AT Potassium channel tetramerisation domain containing 5, mRNA (cDNA clone MGC:28594 IMAGE:4215964) mm
MU19KSUBC:TC39274_AT Potassium channel tetramerisation domain containing 5, mRNA (cDNA clone MGC:28594 IMAGE:4215964) mm
RAE230B:1392292_AT potassium channel tetramerisation domain containing 5 (predicted) rn
RAT230_2:1392292_AT potassium channel tetramerisation domain containing 5 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6813 potassium ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
8076 voltage-gated potassium channel complex inferred from electronic annotation QuickGO AmiGO
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5249 voltage-gated potassium channel activity inferred from electronic annotation QuickGO AmiGO
5515 protein binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_508238 C52B11.3 [Caenorhabditis elegans] sp|Q18775|YYI3_CAEEL Probable G-protein coupled receptor C52B11.3 0.0
blast AAA82470 Hypothetical protein C52B11.3 [Caenorhabditis elegans] 0.0
blast CAE63568 Hypothetical protein CBG08056 [Caenorhabditis briggsae] 0.0
blast AAA82468 Temporarily assigned gene name protein 303 [Caenorhabditis elegans] ref|NP_508239.1| Temporarily Assigned Gene name family member (tag-303) [Caenorhabditis elegans] 1.0E-149
blast CAE63569 Hypothetical protein CBG08057 [Caenorhabditis briggsae] 1.0E-116
blast XP_693824 PREDICTED: similar to potassium channel tetramerisation domain containing 2 [Danio rerio] 4.0E-58
Protein Domains
Database ID Description E-Value
Pfam IPR003131 EMBL-EBI K+ channel tetramerisation 1.4E-35
Pfam IPR003131 EMBL-EBI K+ channel tetramerisation 1.4E-35
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 2.0E-96
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000006105 6 115-137,150-172,187-209,230-252,280-302,476-498
Sequence
Target Sequence 
>C. ELEGANS:191361_AT
atggattccactatgggtccagctcgagcagctgggtgcggcttaatgttggcgggaagg
tattccaaacgacaagatcaacgctgatgcgtgagccgtgctcgtttctctaccgcctgt
gccaagacgagatgggcctcccaactgatcgggatgagaccggcgcctacttgatcgatc
gggacccggactttttctcgcccatcttgaactatctaagacatggcaaactgatcatga
acccgggactttcggaagaaggaattcttgcggaagctgatttttataacttgccaagtt
tgagtcagctgatcatggatcgtattcaagacagggagaatagtgttaaagatgcgacta
acaaatttgtgtaccgcgtgctgcagtgtcacgaggaggagctcgcttcggtggtatctg
ctatgacggatgggtggaagattgttcaagtagtcccaatcaactccaactacaccaact
acactaccgaacagcctcaagagtacctgtgcatcgt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATGGATTCCACTATGGGTCCAGCTC 607 51 227 Antisense
GGGTGCGGCTTAATGTTGGCGGGAA 243 497 260 Antisense
CAACGCTGATGCGTGAGCCGTGCTC 468 187 305 Antisense
CAAGACGAGATGGGCCTCCCAACTG 699 183 349 Antisense
TACTTGATCGATCGGGACCCGGACT 363 645 394 Antisense
TTCTCGCCCATCTTGAACTATCTAA 300 693 421 Antisense
GGCAAACTGATCATGAACCCGGGAC 126 533 451 Antisense
ACGAGGAGGAGCTCGCTTCGGTGGT 481 93 617 Antisense
CTTCGGTGGTATCTGCTATGACGGA 7 221 632 Antisense
CAAGTAGTCCCAATCAACTCCAACT 570 183 673 Antisense
AGCCTCAAGAGTACCTGTGCATCGT 710 83 719 Antisense
Sequence Source Affymetrix Proprietary Database