[Home] | [Total List]

[191348_s_at] EGF-like protein slit like

Description F40E10.4 /REP_DB=WormBase Gene ID /WP=CE23711 /TR=Q20204 /GB=CAA93668.2 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=EGF-like protein slit like
Cluster 6grp_highest_10_10 > 21      6grp_high1_10_10 > 13      4grp_highest_8_8 > 48      4grp_high_8_8 > 42      6grp_highest_nonorm > 70      6grp_total > 14      4grp_total > 45      6grp_highest_sub > De      6grp_cgc > 31      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 427
1 2 3 4 range
A 557.5
(3)
P 		351.9
(0.1)
P 		234.6
(-1.5)
P 		130.4
(-3)
P 		427
B 406
(2.2)
P 		434.9
(3)
P 		296.3
(-0.9)
P 		219.6
(-3)
P 		215
C 525.8
(3)
P 		305.5
(-0.9)
P 		234.6
(-2.2)
P 		188.2
(-3)
P 		338
avr 496.4
(3) 		364.1
(0.5) 		255.2
(-1.6) 		179.4
(-3) 		317

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 327
1 2 3 4 5 6 range
A 457.8
(3)
P 		420.6
(2.3)
P 		262.4
(-0.6)
P 		284
(-0.2)
P 		228.7
(-1.2)
P 		130.6
(-3)
P 		327
B 431.7
(3)
P 		389.9
(2.2)
P 		317.1
(0.7)
P 		251.1
(-0.6)
P 		182.4
(-2)
P 		134.2
(-3)
P 		298
C 445.9
(3)
P 		379.3
(1.6)
P 		317.6
(0.4)
P 		311
(0.2)
P 		199.5
(-2.1)
P 		153.2
(-3)
P 		293
avr 445.1
(3) 		396.6
(2) 		299
(0.1) 		282
(-0.2) 		203.5
(-1.7) 		139.3
(-3) 		306
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 184
1 2 3 4 range
A 203
(3)
P 		76.4
(-1.1)
P 		61.3
(-1.6)
P 		19.1
(-3)
P 		184
B 129.5
(3)
P 		107.4
(1.4)
P 		68.7
(-1.4)
P 		46.8
(-3)
P 		83
C 174.1
(3)
P 		87.8
(-0.6)
P 		81.8
(-0.9)
P 		31.7
(-3)
P 		142
avr 168.9
(3) 		90.5
(-0.4) 		70.6
(-1.3) 		32.5
(-3) 		136

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 134
1 2 3 4 5 6 range
A 84.4
(-0.3)
P 		149.6
(3)
P 		57.1
(-1.7)
P 		72
(-1)
P 		69
(-1.1)
P 		31.8
(-3)
P 		118
B 150.2
(3)
P 		129.8
(1.8)
P 		77
(-1.4)
P 		66.5
(-2)
P 		74.1
(-1.6)
P 		50
(-3)
P 		100
C 165.3
(3)
P 		115.7
(0.4)
P 		80.8
(-1.4)
P 		62.5
(-2.4)
P 		64.6
(-2.3)
P 		51.3
(-3)
P 		114
avr 133.3
(3) 		131.7
(2.9) 		71.6
(-1.2) 		67
(-1.5) 		69.2
(-1.3) 		44.4
(-3) 		89
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191348_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17638
Sequence Type Exemplar sequence
Representative Public ID F40E10.4 NCBI
Target Description F40E10.4 /REP_DB=WormBase Gene ID /WP=CE23711 /TR=Q20204 /GB=CAA93668.2 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=EGF-like protein slit like
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_078036(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_078036 NCBI Caenorhabditis elegans SLiT (Drosophila) homolog family member (slt-1) (slt-1) mRNA, complete cds. 10/11 None
GENEFINDER00000014858 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:14679948:14682946:1 10/11 None
F40E10.4 ENSEMBL cdna:known chromosome:CEL140:X:14674294:14683238:1 gene:F40E10.4 10/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000014847 6/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:14674293-14682946(+) 100.0 100.0
Public Domain and Genome References
Gene Title EGF-like protein slit like
Gene Symbol slt-1
Ensembl F40E10.4
Entrez Gene 181562 Entrez gene
SwissProt Q20204 EMBL-EBI
WormBase CE32412 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.20172.1.S1_S_AT slit homolog 2 (Drosophila) cfa
CANINE_2:CFAAFFX.25452.1.S1_S_AT slit homolog 2 (Drosophila) cfa
DROSOPHILA_2:1631881_A_AT slit dm
DROSGENOME1:143354_AT slit dm
CHICKEN:GGA.909.1.S1_AT slit homolog 2 (Drosophila) gga
HG-U133_PLUS_2:209897_S_AT slit homolog 2 (Drosophila) hs
HG-U133A:209897_S_AT slit homolog 2 (Drosophila) hs
HG-FOCUS:209897_S_AT slit homolog 2 (Drosophila) hs
HG-U133A_2:209897_S_AT slit homolog 2 (Drosophila) hs
HU35KSUBA:RC_AA486868_S_AT slit homolog 2 (Drosophila) hs
HU35KSUBD:RC_H81302_AT slit homolog 2 (Drosophila) hs
HU35KSUBD:RC_AA489463_AT slit homolog 2 (Drosophila) hs
U133_X3P:G4151204_3P_A_AT slit homolog 2 (Drosophila) hs
HG-U95AV2:39634_AT slit homolog 2 (Drosophila) hs
HG-U95B:47175_R_AT Slit homolog 2 (Drosophila) hs
HG-U95E:71816_AT Slit homolog 2 (Drosophila) hs
HU35KSUBD:RC_AA477708_AT Slit homolog 2 (Drosophila) hs
MG-U74BV2:163470_AT slit homolog 2 (Drosophila) mm
MOE430A:1451430_AT slit homolog 2 (Drosophila) mm
MOUSE430A_2:1451430_AT slit homolog 2 (Drosophila) mm
MOUSE430_2:1451430_AT slit homolog 2 (Drosophila) mm
MOE430A:1424659_AT slit homolog 2 (Drosophila) mm
MOUSE430A_2:1424659_AT slit homolog 2 (Drosophila) mm
MOUSE430_2:1424659_AT slit homolog 2 (Drosophila) mm
MOE430B:1458140_AT slit homolog 2 (Drosophila) mm
MOUSE430_2:1458140_AT slit homolog 2 (Drosophila) mm
MOE430B:1446392_AT SLIT2 (Slit2) mm
MOUSE430_2:1446392_AT SLIT2 (Slit2) mm
MOE430B:1437978_AT SLIT2 (Slit2) mm
MOUSE430_2:1437978_AT SLIT2 (Slit2) mm
MOE430B:1440650_AT SLIT2 (Slit2) mm
MOUSE430_2:1440650_AT SLIT2 (Slit2) mm
MOE430B:1442322_AT SLIT2 (Slit2) mm
MOUSE430_2:1442322_AT SLIT2 (Slit2) mm
MOE430B:1443576_AT SLIT2 (Slit2) mm
MOUSE430_2:1443576_AT SLIT2 (Slit2) mm
MOE430B:1447056_AT SLIT2 (Slit2) mm
MOUSE430_2:1447056_AT SLIT2 (Slit2) mm
MG-U74CV2:168333_AT SLIT2 (Slit2) mm
RAE230A:1369346_AT slit homolog 2 (Drosophila) rn
RAT230_2:1369346_AT slit homolog 2 (Drosophila) rn
RAE230B:1395986_AT slit homolog 2 (Drosophila) rn
RAT230_2:1395986_AT slit homolog 2 (Drosophila) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7155 cell adhesion inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5198 structural molecule activity inferred from electronic annotation QuickGO AmiGO
5509 calcium ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA93668 Hypothetical protein F40E10.4 [Caenorhabditis elegans] emb|CAB63434.2| Hypothetical protein F40E10.4 [Caenorhabditis elegans] ref|NP_510437.2| SLiT (Drosophila) homolog family member (slt-1) [Caenorhabditis elegans] 0.0
blast CAE63213 Hypothetical protein CBG07570 [Caenorhabditis briggsae] 0.0
blast AAF58097 CG8355-PC, isoform C [Drosophila melanogaster] ref|NP_476727.1| CG8355-PC, isoform C [Drosophila melanogaster] sp|P24014|SLIT_DROME Slit protein precursor [Contains: Slit protein N-product; Slit protein C-product] 0.0
blast AAM70966 CG8355-PB, isoform B [Drosophila melanogaster] ref|NP_476729.1| CG8355-PB, isoform B [Drosophila melanogaster] 5.0E-86
Protein Domains
Database ID Description E-Value
Pfam IPR000483 EMBL-EBI Cysteine-rich flanking region, C-terminal 4.6E-4
Pfam IPR001791 EMBL-EBI Laminin G 2.8E-22
Pfam IPR006209 EMBL-EBI EGF-like domain 4.9E-8
Pfam IPR006209 EMBL-EBI EGF-like domain 6.3E-6
Pfam IPR006209 EMBL-EBI EGF-like domain 3.8E-9
Pfam IPR006209 EMBL-EBI EGF-like domain 1.5E-8
Pfam IPR006209 EMBL-EBI EGF-like domain 9.5E-7
Pfam IPR006209 EMBL-EBI EGF-like domain 1.9E-6
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.24
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.034
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.0035
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.054
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.42
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.18
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.0043
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 5.0E-4
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.0033
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.14
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.052
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 1.2E-5
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 3.8E-4
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 7.9E-5
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.075
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 1.4E-4
Pfam IPR000372 EMBL-EBI Cysteine-rich flanking region, N-terminal 1.3E-8
Pfam IPR000372 EMBL-EBI Cysteine-rich flanking region, N-terminal 2.8E-11
Pfam IPR000372 EMBL-EBI Cysteine-rich flanking region, N-terminal 5.9E-9
Pfam IPR000372 EMBL-EBI Cysteine-rich flanking region, N-terminal 6.4E-9
Pfam IPR001791 EMBL-EBI Laminin G 2.8E-22
Pfam IPR006209 EMBL-EBI EGF-like domain 1.5E-8
Pfam IPR006209 EMBL-EBI EGF-like domain 9.5E-7
Pfam IPR006209 EMBL-EBI EGF-like domain 1.9E-6
Sequence
Target Sequence 
>C. ELEGANS:191348_S_AT
gtgggaaatctgaccagctaatcacaaaaggcaaagaaatgctgtatatcggaggactgc
caatcgaaaaatctcaagatgcaaagagaaggttccacgtgaagaattcagagagtttga
aaggttgtatcagttcaatcacgataaatgaagtgccgatcaatttgcaacaagctctag
agaacgtcaacacagagcaaagctgctctgcgaccgtaaacttttgtgcaggcatcgatt
gtggaaacggaaagtgcacgaataatgccctatcaccaaaaggctacatgtgccaatgcg
attctcatttttcaggagagcattgtgatgaaaaaagaatcaaatgtgacaagcaaaagt
tcagaaggcatcatatagaaaatgagtgtagatcggttgacagaatcaagatagcagagt
gtaatggttactgtggaggcgaacagaattgttgcactgctgtgaagaaaaagcagagaa
aagtgaaaatgatatgcaaaaatggaacaacgtatgttagagaattcctagctcaaacaa
atacttatttttccagaaaaatctccactgttcacattattcgtcagtgccaat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGGGAAATCTGACCAGCTAATCAC 252 489 3707 Antisense
GCTGTATATCGGAGGACTGCCAATC 523 293 3747 Antisense
GTGCCGATCAATTTGCAACAAGCTC 12 479 3859 Antisense
AGAGCAAAGCTGCTCTGCGACCGTA 369 69 3900 Antisense
GCGACCGTAAACTTTTGTGCAGGCA 444 287 3916 Antisense
TTGTGCAGGCATCGATTGTGGAAAC 255 701 3930 Antisense
GTGCACGAATAATGCCCTATCACCA 21 481 3960 Antisense
ATGCCCTATCACCAAAAGGCTACAT 398 41 3971 Antisense
GGCTACATGTGCCAATGCGATTCTC 6 539 3988 Antisense
GAAAAATCTCCACTGTTCACATTAT 679 355 4262 Antisense
GTTCACATTATTCGTCAGTGCCAAT 130 443 4276 Antisense
Sequence Source Affymetrix Proprietary Database