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[191336_at] G-protein coupled receptor

Description K06C4.8 /REP_DB=WormBase Gene ID /WP=CE11816 /TR=Q9GYH2 /GB=AAF98228.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=G-protein coupled receptor
Cluster 6grp_high1_10_10 > 32      6grp_total > 20      4grp_total > 03      6grp_high1_sub > 02_03      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 451
1 2 3 4 range
A 182.6
(-1.9)
A 		162
(-2.3)
A 		122.6
(-3)
A 		456.4
(3)
P 		334
B 136.5
(-2.1)
A 		131.2
(-2.2)
A 		82.2
(-3)
A 		463.4
(3)
P 		381
C 186.6
(-2)
P 		131.3
(-2.8)
A 		119.1
(-3)
P 		532.8
(3)
P 		414
avr 168.6
(-2) 		141.5
(-2.5) 		108
(-3) 		484.2
(3) 		376

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 155
1 2 3 4 5 6 range
A 231.2
(0.1)
P 		299.2
(3)
P 		238.8
(0.4)
P 		239.2
(0.4)
A 		158.6
(-3)
A 		188.4
(-1.7)
A 		141
B 186.4
(-2.3)
P 		226.9
(0.1)
P 		276.9
(3)
P 		192.2
(-1.9)
P 		173.6
(-3)
P 		186.8
(-2.2)
P 		103
C 160.9
(-2.2)
A 		254.8
(2.5)
P 		265.3
(3)
P 		218
(0.6)
M 		159.5
(-2.3)
A 		144.7
(-3)
P 		121
avr 192.8
(-1.2) 		260.3
(3) 		260.3
(3) 		216.5
(0.3) 		163.9
(-3) 		173.3
(-2.4) 		96
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 80
1 2 3 4 range
A 66.5
(2.9)
A 		35.2
(-2.5)
A 		32.1
(-3)
A 		66.8
(3)
P 		35
B 43.5
(-1.2)
A 		32.4
(-2)
A 		19.1
(-3)
A 		98.8
(3)
P 		80
C 61.8
(-0.2)
P 		37.7
(-3)
A 		41.5
(-2.6)
P 		89.8
(3)
P 		52
avr 57.3
(-0.1) 		35.1
(-2.5) 		30.9
(-3) 		85.1
(3) 		54

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 64
1 2 3 4 5 6 range
A 42.6
(-3)
P 		106.4
(3)
P 		52
(-2.1)
P 		60.7
(-1.3)
A 		47.9
(-2.5)
A 		45.9
(-2.7)
A 		64
B 64.9
(0.4)
P 		75.5
(3)
P 		67.2
(1)
P 		50.9
(-3)
P 		70.5
(1.8)
P 		69.6
(1.6)
P 		25
C 59.6
(-0.2)
A 		77.8
(3)
P 		67.5
(1.2)
P 		43.8
(-3)
M 		51.6
(-1.6)
A 		48.5
(-2.2)
P 		34
avr 55.7
(-2.3) 		86.6
(3) 		62.2
(-1.2) 		51.8
(-3) 		56.7
(-2.2) 		54.7
(-2.5) 		35
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191336_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.12217
Sequence Type Exemplar sequence
Representative Public ID K06C4.8 NCBI
Target Description K06C4.8 /REP_DB=WormBase Gene ID /WP=CE11816 /TR=Q9GYH2 /GB=AAF98228.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=G-protein coupled receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072900(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072900 NCBI Caenorhabditis elegans K06C4.8 (K06C4.8) mRNA, complete cds. 11/11 None
GENEFINDER00000018195 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:8909867:8911980:1 11/11 None
K06C4.8 ENSEMBL cdna:known chromosome:CEL140:V:8910216:8911980:1 gene:K06C4.8 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:8910216-8911981(+) 100.0 100.0
Public Domain and Genome References
Gene Title G-protein coupled receptor
Ensembl K06C4.8
Entrez Gene 187065 Entrez gene
SwissProt Q9GYH2 EMBL-EBI
WormBase CE11816 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7186 G-protein coupled receptor protein signaling pathway inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
1584 rhodopsin-like receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAF98228 Hypothetical protein K06C4.8 [Caenorhabditis elegans] ref|NP_505301.1| K06C4.8 [Caenorhabditis elegans] 1.0E-179
blast AAL08039 Hypothetical protein K06C4.9 [Caenorhabditis elegans] ref|NP_505300.1| K06C4.9 [Caenorhabditis elegans] 1.0E-124
blast T30050 hypothetical protein K06C4.9 - Caenorhabditis elegans 1.0E-124
Protein Domains
Database ID Description E-Value
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 4.2E-11
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 4.2E-11
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_505301.1 7 20-42,54-76,86-108,165-184,194-216,246-268,283-305
K06C4.8 7 20-42,54-76,86-108,165-184,194-216,246-268,283-305
GENEFINDER00000018195 7 34-56,69-91,101-123,180-199,209-231,261-283,298-320
Sequence
Target Sequence 
>C. ELEGANS:191336_AT
acgggctatgacctgcataatcgcaatttcaattttgttcaatgctcctaggttcttcga
gttcaaggccaatctaatcacaggtgtcatcggttttggtctagcacatatttcaaaaaa
tgaatggtatttctacttatattatggaattcgtgcaataatttttgacgcattgatacc
gttttctatcattgctgtaacaaatattcaagttatccagcagcttcgaaaatcaaacga
agaaagaaaattgatgacaacgcaacaacaaaaagataacaaaactactacaatgctttt
ggttatgatatttatgtatgcgatttgtcattttttatgtacaagtgtcaagtttatcaa
tttgttctcccataattatgtgcaatttcagttcgttatatttaaaatcattcatcacat
atcgaatgtacttctagtcttttactctgcctcaacattcttcatttatctcatattctc
tgaaaaatatcgaaatgttctctctacatgtgttacttgcagaaatactgatgaattaac
agtatcaagtcgaggaagacagaatacaaaaactacccgatcaaattctca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ACGGGCTATGACCTGCATAATCGCA 308 93 453 Antisense
TTGTTCAATGCTCCTAGGTTCTTCG 249 679 487 Antisense
GGTTCTTCGAGTTCAAGGCCAATCT 235 507 503 Antisense
AGGCCAATCTAATCACAGGTGTCAT 38 55 518 Antisense
AGGTGTCATCGGTTTTGGTCTAGCA 625 57 534 Antisense
GATACCGTTTTCTATCATTGCTGTA 340 425 627 Antisense
ATTCAAGTTATCCAGCAGCTTCGAA 674 9 658 Antisense
AAGTTTATCAATTTGTTCTCCCATA 475 155 802 Antisense
TGTACTTCTAGTCTTTTACTCTGCC 30 561 879 Antisense
TCTTCATTTATCTCATATTCTCTGA 382 617 911 Antisense
CAAAAACTACCCGATCAAATTCTCA 348 189 1019 Antisense
Sequence Source Affymetrix Proprietary Database