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[191329_s_at] protein kinase

Description K07C11.2 /REP_DB=WormBase Gene ID /WP=CE21025 /GEN=air-1 /TR=Q21271 /GB=AAA96180.2 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=protein kinase
Cluster 6grp_highest_10_10 > 78      6grp_high1_10_10 > 87      4grp_highest_8_8 > 18      4grp_high_8_8 > 62      6grp_highest_nonorm > 98      6grp_total > 87      4grp_total > 57      6grp_highest_sub > In      6grp_cgc > 59      6grp_high1_sub > In      6grp_cgc_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 590
1 2 3 4 range
A 477.6
(-1)
P 		684.2
(1.6)
P 		799.8
(3)
P 		321.2
(-3)
P 		479
B 452.8
(-1.4)
P 		707
(1.3)
P 		860.2
(3)
P 		308.7
(-3)
P 		552
C 413
(-1.4)
P 		645.5
(1.1)
P 		819.4
(3)
P 		269.8
(-3)
P 		550
avr 447.8
(-1.3) 		678.9
(1.3) 		826.5
(3) 		299.9
(-3) 		527

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1585
1 2 3 4 5 6 range
A 442.9
(-2.7)
P 		423.9
(-2.8)
P 		385.6
(-3)
P 		679.1
(-1.6)
P 		1003.3
(-0)
P 		1632
(3)
P 		1246
B 446.4
(-2.9)
P 		429.6
(-3)
P 		422.5
(-3)
P 		573.5
(-2.3)
P 		1072.9
(-0.1)
P 		1753
(3)
P 		1331
C 486.4
(-2.8)
P 		427.1
(-3)
P 		516.1
(-2.7)
P 		667
(-2.1)
P 		1097.8
(-0.4)
P 		1970.3
(3)
P 		1543
avr 458.6
(-2.9) 		426.9
(-3) 		441.4
(-2.9) 		639.9
(-2.1) 		1058
(-0.2) 		1785.1
(3) 		1358
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 240
1 2 3 4 range
A 173.9
(1.7)
P 		148.5
(0.8)
P 		209.1
(3)
P 		47
(-3)
P 		162
B 144.4
(0.5)
P 		174.6
(1.9)
P 		199.3
(3)
P 		65.8
(-3)
P 		134
C 136.7
(-0.7)
P 		185.6
(0.5)
P 		285.6
(3)
P 		45.5
(-3)
P 		240
avr 151.7
(0.3) 		169.6
(0.9) 		231.3
(3) 		52.8
(-3) 		179

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 578
1 2 3 4 5 6 range
A 81.6
(-3)
P 		150.8
(-1.7)
P 		84
(-3)
P 		172.2
(-1.3)
P 		302.7
(1.2)
P 		397.3
(3)
P 		316
B 155.3
(-2.4)
P 		143
(-2.6)
P 		102.6
(-3)
P 		151.9
(-2.5)
P 		435.9
(0.6)
P 		653.7
(3)
P 		551
C 180.3
(-2.4)
P 		130.3
(-3)
P 		131.3
(-3)
P 		134.1
(-3)
P 		355.2
(-0.5)
P 		659.6
(3)
P 		529
avr 139.1
(-2.6) 		141.4
(-2.5) 		106
(-3) 		152.7
(-2.4) 		364.6
(0.3) 		570.2
(3) 		464
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191329_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11597
Sequence Type Exemplar sequence
Representative Public ID K07C11.2 NCBI
Target Description K07C11.2 /REP_DB=WormBase Gene ID /WP=CE21025 /GEN=air-1 /TR=Q21271 /GB=AAA96180.2 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072718(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072718 NCBI Caenorhabditis elegans Aurora/Ipl1 Related kinase family member (air-1) (air-1) mRNA, complete cds. 11/11 None
SNAP00000021029 ENSEMBL cdna:SNAP chromosome:CEL140:V:8224092:8225829:1 11/11 None
GENEFINDER00000021040 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:8224092:8225829:1 11/11 None
K07C11.2.1 ENSEMBL cdna:known chromosome:CEL140:V:8224001:8226158:1 gene:K07C11.2 11/11 None
K07C11.2.2 ENSEMBL cdna:known chromosome:CEL140:V:8224079:8226104:1 gene:K07C11.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:8224092-8225830(+) 100.0 100.0
Public Domain and Genome References
Gene Title protein kinase
Gene Symbol air-1
Ensembl K07C11.2
Entrez Gene 179202 Entrez gene
SwissProt Q21271 EMBL-EBI
WormBase CE21025 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA96180 Aurora/ipl1 related kinase protein 1 [Caenorhabditis elegans] ref|NP_505119.1| Aurora/Ipl1 Related kinase family member (air-1) [Caenorhabditis elegans] gb|AAC70944.1| aurora/Ipl1-related protein kinase 1 [Caenorhabditis elegans] 1.0E-179
blast CAE66101 Hypothetical protein CBG11321 [Caenorhabditis briggsae] emb|CAE56940.1| Hypothetical protein CBG24785 [Caenorhabditis briggsae] 1.0E-157
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 5.0E-59
hanks 2.1.17 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; TWITCH 4.0E-69
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 3.8E-80
Sequence
Target Sequence 
>C. ELEGANS:191329_S_AT
gtcattctcgactatgccagcagaggagaattatttaatgtcctccaatcacaacctgga
cacaaagtgaatgaggtcattgccggaagatttgtgcgacagctggccaatgcgttgcat
tactgccattcgaaaggagttattcacagagacattaagcctgaaaatcttcttcttgat
tcgaagctcaatctgaagcttgccgatttcggatggtccgtcgttgctgatcactcgaaa
cgccatacattgtgcggtaccatggattatcttgctccggaaatggtttccaatcagcca
catgactttaatgttgacatttgggcaattggaattcttctcttcgaaatgcttgttgga
tatgctccgttcgccaatcaaactggtgataaattgatcgccagaatcaaggagtgcaag
atttatattccaagtgttgtgactgacggagctgccagtttgataaatgcaataatcaaa
aaggaaccccaagaacgtctcccacttgttgacatcatggctcatccgt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTCATTCTCGACTATGCCAGCAGAG 81 469 367 Antisense
TTAATGTCCTCCAATCACAACCTGG 165 685 401 Antisense
AATGCGTTGCATTACTGCCATTCGA 528 163 475 Antisense
GATTTCGGATGGTCCGTCGTTGCTG 175 427 571 Antisense
TGCTGATCACTCGAAACGCCATACA 52 583 591 Antisense
ACGCCATACATTGTGCGGTACCATG 59 91 606 Antisense
GGTACCATGGATTATCTTGCTCCGG 236 505 622 Antisense
GAATTCTTCTCTTCGAAATGCTTGT 151 325 698 Antisense
CTCCGTTCGCCAATCAAACTGGTGA 272 235 731 Antisense
GTGTTGTGACTGACGGAGCTGCCAG 261 485 800 Antisense
CTTGTTGACATCATGGCTCATCCGT 121 219 871 Antisense
Sequence Source Affymetrix Proprietary Database