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[191301_s_at] histidine ammonia-lyase

Description F47B10.2 /REP_DB=WormBase Gene ID /WP=CE03352 /TR=SW:Q20502 /GB=CAA91982.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=histidine ammonia-lyase
Cluster 6grp_highest_10_10 > 40      6grp_high1_10_10 > 04      4grp_highest_8_8 > 60      4grp_high_8_8 > 26      6grp_highest_nonorm > 01      6grp_total > 14      4grp_total > 38      6grp_highest_sub > De      6grp_high1_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1338
1 2 3 4 range
A 2648.4
(3)
P 		2170.8
(0.7)
P 		1395.1
(-3)
P 		1867.9
(-0.7)
P 		1253
B 2086
(3)
P 		1603.4
(-0.9)
P 		1350.6
(-3)
P 		1823.4
(0.9)
P 		735
C 2308.2
(3)
P 		1572.3
(-1.4)
P 		1310
(-3)
P 		1639.6
(-1)
P 		998
avr 2347.5
(3) 		1782.2
(-0.4) 		1351.9
(-3) 		1777
(-0.4) 		996

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 3349
1 2 3 4 5 6 range
A 3620.8
(3)
P 		2299.2
(0.6)
P 		1513
(-0.8)
P 		1142.7
(-1.5)
P 		762.5
(-2.2)
P 		325.3
(-3)
P 		3296
B 2904.1
(3)
P 		2253.1
(1.5)
P 		1759.8
(0.3)
P 		1233.3
(-0.9)
P 		788.7
(-1.9)
P 		323.4
(-3)
P 		2581
C 3237.4
(3)
P 		2375.6
(1.3)
P 		1944.9
(0.4)
P 		1286.5
(-0.9)
P 		798.8
(-1.9)
P 		271.9
(-3)
P 		2966
avr 3254.1
(3) 		2309.3
(1.1) 		1739.2
(-0.1) 		1220.8
(-1.1) 		783.3
(-2) 		306.9
(-3) 		2947
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 691
1 2 3 4 range
A 964.3
(3)
P 		471.2
(-1.3)
P 		364.7
(-2.2)
P 		273.4
(-3)
P 		691
B 665.2
(3)
P 		396
(-1.6)
P 		313
(-3)
P 		388.6
(-1.7)
P 		352
C 764.1
(3)
P 		452.1
(-0.8)
P 		456.6
(-0.8)
P 		276.5
(-3)
P 		488
avr 797.9
(3) 		439.8
(-1.4) 		378.1
(-2.2) 		312.8
(-3) 		485

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1121
1 2 3 4 5 6 range
A 667.5
(1.8)
P 		817.7
(3)
P 		329.5
(-1)
P 		289.8
(-1.3)
P 		230.1
(-1.8)
P 		79.2
(-3)
P 		739
B 1010.5
(3)
P 		749.9
(1.2)
P 		427.3
(-0.9)
P 		326.7
(-1.6)
P 		320.4
(-1.7)
P 		120.6
(-3)
P 		890
C 1200
(3)
P 		724.9
(0.4)
P 		495
(-0.8)
P 		258.7
(-2.1)
P 		258.5
(-2.1)
P 		91
(-3)
P 		1109
avr 959.3
(3) 		764.2
(1.6) 		417.3
(-0.8) 		291.7
(-1.6) 		269.7
(-1.8) 		96.9
(-3) 		862
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191301_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16526
Sequence Type Exemplar sequence
Representative Public ID F47B10.2 NCBI
Target Description F47B10.2 /REP_DB=WormBase Gene ID /WP=CE03352 /TR=SW:Q20502 /GB=CAA91982.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=histidine ammonia-lyase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077419(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077419 NCBI Caenorhabditis elegans F47B10.2 (F47B10.2) mRNA, complete cds. 11/11 None
SNAP00000040446 ENSEMBL cdna:SNAP chromosome:CEL140:X:10893612:10896248:-1 11/11 None
GENEFINDER00000040453 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:10893612:10896248:-1 11/11 None
F47B10.2 ENSEMBL cdna:known chromosome:CEL140:X:10893490:10896339:-1 gene:F47B10.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:10893611-10896248(-) 100.0 100.0
Public Domain and Genome References
Gene Title histidine ammonia-lyase
Ensembl F47B10.2
Entrez Gene 181279 Entrez gene
SwissProt Q20502 EMBL-EBI
WormBase CE03352 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1592018_AT similar to Histidine ammonia-lyase (Histidase) cfa
CANINE_2:CFAAFFX.10607.1.S1_AT similar to Histidine ammonia-lyase (Histidase) cfa
CHICKEN:GGA.8448.1.S1_AT histidine ammonia-lyase gga
HG-U133_PLUS_2:206643_AT histidine ammonia-lyase hs
HG-U133A:206643_AT histidine ammonia-lyase hs
HG-FOCUS:206643_AT histidine ammonia-lyase hs
HG-U133A_2:206643_AT histidine ammonia-lyase hs
HU35KSUBA:D16626_AT histidine ammonia-lyase hs
HUGENEFL:D16626_AT histidine ammonia-lyase hs
HU35KSUBC:RC_W70115_S_AT histidine ammonia-lyase hs
U133_X3P:G4809282_3P_AT histidine ammonia-lyase hs
HG-U95AV2:40735_AT histidine ammonia-lyase hs
HG-U95C:56905_AT histidine ammonia-lyase hs
HG-U133_PLUS_2:217521_AT Histidine ammonia-lyase hs
HG-U133A_2:217521_AT Histidine ammonia-lyase hs
HG-U133A:217521_AT Histidine ammonia-lyase hs
HG-U133_PLUS_2:237967_AT Histidine ammonia-lyase hs
HG-U133B:237967_AT Histidine ammonia-lyase hs
HG-U95C:56900_R_AT Histidine ammonia-lyase hs
HU35KSUBA:RC_AA233369_AT Histidine ammonia-lyase hs
HU35KSUBD:RC_AA342227_AT Histidine ammonia-lyase hs
HU35KSUBD:RC_R05984_AT Histidine ammonia-lyase hs
U133_X3P:HS.276590.0.A1_3P_AT Histidine ammonia-lyase hs
U133_X3P:HS.282718.0.A1_3P_AT Histidine ammonia-lyase hs
MU11KSUBB:MSA.738.0_S_AT histidine ammonia lyase mm
MG-U74AV2:92833_AT histidine ammonia lyase mm
MOE430A:1418645_AT histidine ammonia lyase mm
MOUSE430A_2:1418645_AT histidine ammonia lyase mm
MOUSE430_2:1418645_AT histidine ammonia lyase mm
MU19KSUBC:TC36664_S_AT Histidine ammonia lyase (Hal), mRNA mm
RG-U34A:M58308_AT histidine ammonia lyase rn
RG-U34A:AB002393_G_AT histidine ammonia lyase rn
RG-U34A:AB002393_AT histidine ammonia lyase rn
RAE230A:1387307_AT histidine ammonia lyase rn
RAT230_2:1387307_AT histidine ammonia lyase rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6548 histidine catabolism inferred from electronic annotation QuickGO AmiGO
9058 biosynthesis inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5737 cytoplasm inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4397 histidine ammonia-lyase activity inferred from electronic annotation QuickGO AmiGO
16211 ammonia ligase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA91982 Hypothetical protein F47B10.2 [Caenorhabditis elegans] ref|NP_509820.1| F47B10.2 [Caenorhabditis elegans] sp|Q20502|HUTH_CAEEL Probable histidine ammonia-lyase (Histidase) 0.0
blast CAE70800 Hypothetical protein CBG17560 [Caenorhabditis briggsae] 0.0
blast NP_989735 histidine ammonia-lyase [Gallus gallus] gb|AAO73411.1| histidine ammonia lyase [Gallus gallus] 1.0E-166
Protein Domains
Database ID Description E-Value
Pfam IPR001106 EMBL-EBI Phenylalanine/histidine ammonia-lyase 1.0E-126
Pfam IPR001106 EMBL-EBI Phenylalanine/histidine ammonia-lyase 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:191301_S_AT
tgatttcttggcgattgccgttgccgagcttgctcagatgagcgaacgccgtttggaacg
tttagtgaacaaagagctcagtggacttccaactttcttgactccagacggtggtctaaa
ctctggctttatgactgttcaactttgtgctgcaagtttggtttctgaaaacaaggtact
atgtcatccatcttcggtcgatagcattccaaccagctgcaaccaggaggatcacgtaag
catgggtggatttgcagcccgaaaagcacttaccgtagttgagcatgttgaagctgttct
agccatggaattgctagctgcatgccagggaattgaattcctcaaaccgttgatttctac
agctcctcttcacaaaatttaccaacttgttagatctgtggcaccaccgctcaacgaaga
tcgctatatgaaacctgagatcgatgctgtgctt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGATTTCTTGGCGATTGCCGTTGCC 437 563 1419 Antisense
AACTTTCTTGACTCCAGACGGTGGT 453 139 1509 Antisense
AGACGGTGGTCTAAACTCTGGCTTT 471 71 1524 Antisense
ATGACTGTTCAACTTTGTGCTGCAA 467 45 1549 Antisense
AAGGTACTATGTCATCCATCTTCGG 684 159 1591 Antisense
CGATAGCATTCCAACCAGCTGCAAC 359 249 1617 Antisense
TGCAGCCCGAAAAGCACTTACCGTA 164 567 1671 Antisense
GGAATTGCTAGCTGCATGCCAGGGA 74 533 1725 Antisense
TCAAACCGTTGATTTCTACAGCTCC 52 629 1760 Antisense
CTACAGCTCCTCTTCACAAAATTTA 313 227 1775 Antisense
GAAACCTGAGATCGATGCTGTGCTT 471 357 1848 Antisense
Sequence Source Affymetrix Proprietary Database