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[191274_s_at] lysosomal carboxypeptidase

Description F23B2.11 /REP_DB=WormBase Gene ID /WP=CE09591 /TR=O02252 /GB=CAB05185.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=lysosomal carboxypeptidase
Cluster 6grp_highest_10_10 > 42      6grp_high1_10_10 > 25      4grp_highest_8_8 > 26      4grp_high_8_8 > 59      6grp_highest_nonorm > 21      6grp_total > 03      4grp_total > 60      6grp_highest_sub > 02      6grp_cgc > 41      6grp_high1_sub > 01_02      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1982
1 2 3 4 range
A 2870.1
(1.1)
P 		2692.9
(0.5)
P 		3418.2
(3)
P 		1650
(-3)
P 		1768
B 2885.7
(2)
P 		2652
(1.2)
P 		3175.3
(3)
P 		1436.6
(-3)
P 		1739
C 2595.3
(1.9)
P 		2368.5
(0.9)
P 		2835
(3)
P 		1488.8
(-3)
P 		1346
avr 2783.7
(1.7) 		2571.1
(0.9) 		3142.8
(3) 		1525.1
(-3) 		1618

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 950
1 2 3 4 5 6 range
A 1542.4
(1.4)
P 		1788.8
(3)
P 		1009.1
(-1.9)
P 		1289.5
(-0.2)
P 		953.4
(-2.3)
P 		839.1
(-3)
P 		950
B 1621.9
(2.2)
P 		1734
(3)
P 		924.4
(-3)
P 		1166.7
(-1.2)
P 		926.7
(-3)
P 		976.8
(-2.6)
P 		810
C 1615.9
(2)
P 		1717.2
(3)
P 		1295.5
(-1)
P 		1194.2
(-2)
P 		1160.6
(-2.3)
P 		1091.2
(-3)
P 		626
avr 1593.4
(1.8) 		1746.7
(3) 		1076.3
(-2.2) 		1216.8
(-1.1) 		1013.6
(-2.7) 		969
(-3) 		778
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 804
1 2 3 4 range
A 1045
(3)
P 		584.5
(-0.4)
P 		893.6
(1.9)
P 		241.5
(-3)
P 		804
B 920.2
(3)
P 		655
(0.4)
P 		735.8
(1.2)
P 		306.1
(-3)
P 		614
C 859.1
(1.9)
P 		681
(0.5)
P 		988.1
(3)
P 		251
(-3)
P 		737
avr 941.4
(3) 		640.2
(0.3) 		872.5
(2.4) 		266.2
(-3) 		675

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 432
1 2 3 4 5 6 range
A 284.3
(-1.9)
P 		636.2
(3)
P 		219.8
(-2.8)
P 		327
(-1.3)
P 		287.7
(-1.8)
P 		204.3
(-3)
P 		432
B 564.3
(2.8)
P 		577.2
(3)
P 		224.5
(-3)
P 		309
(-1.6)
P 		376.5
(-0.4)
P 		364.3
(-0.6)
P 		353
C 599
(3)
P 		524
(1.7)
P 		329.7
(-1.5)
P 		240.1
(-3)
P 		375.5
(-0.7)
P 		365.3
(-0.9)
P 		359
avr 482.5
(1.2) 		579.1
(3) 		258
(-3) 		292
(-2.4) 		346.6
(-1.3) 		311.3
(-2) 		321
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191274_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9425
Sequence Type Exemplar sequence
Representative Public ID F23B2.11 NCBI
Target Description F23B2.11 /REP_DB=WormBase Gene ID /WP=CE09591 /TR=O02252 /GB=CAB05185.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=lysosomal carboxypeptidase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069197(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069197 NCBI Caenorhabditis elegans Prolyl Carboxy Peptidase like family member (pcp-3) (pcp-3) mRNA, complete cds. 11/11 None
SNAP00000024648 ENSEMBL cdna:SNAP chromosome:CEL140:IV:9155244:9158995:-1 11/11 None
F23B2.11.2 ENSEMBL cdna:known chromosome:CEL140:IV:9155059:9159452:-1 gene:F23B2.11 11/11 None
F23B2.11.1 ENSEMBL cdna:known chromosome:CEL140:IV:9155127:9159452:-1 gene:F23B2.11 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:9155249-9159458(-) 100.0 100.0
Public Domain and Genome References
Gene Title lysosomal carboxypeptidase
Gene Symbol pcp-3
Ensembl F23B2.11
Entrez Gene 177740 Entrez gene
SwissProt O02252 EMBL-EBI
WormBase CE09591 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8236 serine-type peptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB05185 Hypothetical protein F23B2.11 [Caenorhabditis elegans] ref|NP_501598.1| Prolyl Carboxy Peptidase like family member (pcp-3) [Caenorhabditis elegans] 0.0
blast CAA92588 Hypothetical protein F23B2.12 [Caenorhabditis elegans] emb|CAB05187.1| Hypothetical protein F23B2.12 [Caenorhabditis elegans] ref|NP_501599.1| Prolyl Carboxy Peptidase like family member (pcp-2) [Caenorhabditis elegans] 0.0
blast CAE74127 Hypothetical protein CBG21793 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR008758 EMBL-EBI Peptidase S28 1.0E-126
Pfam IPR008758 EMBL-EBI Peptidase S28 1.0E-126
Pfam IPR008758 EMBL-EBI Peptidase S28 1.0E-126
Pfam IPR008758 EMBL-EBI Peptidase S28 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_501598.1 1 40-62
F23B2.11.2 1 40-62
F23B2.11.1 1 40-62
SNAP00000024648 1 5-24
Sequence
Target Sequence 
>C. ELEGANS:191274_S_AT
aacattatggaccggactctgctgcaggactcctctggacttggcagacttgctccgaat
ttggatatttccagtctgcagactctggaaatggtatctttggatctccaacacctgtga
atatgtacgttcaaatgtgcatggacgtctttaacaaccaataccagagaacaagtattg
actattcaattgcaaacaccaattacaaatacggagagcgtttccattatagaggaacaa
atgtggttcttccaaatggaaatgttgatccttggcatgcacttggtctgtattatccaa
ctgattcatcagttgtttcatacttaatcgatggaactgctcattgtgctgatatgtatc
cagctagagatgccgatgttccagggctcaaggttgtcagagatctcgtcgatcaaaata
ttgctaaatggttgaatcaatctccagccactggagcaacccagatacctggaactggtt
caacagctaaaccagggactggatcaacttctcaacctgtaacagcttcaactgttcagg
ctacaactaaatctacctcatctgctactattaccttgtca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AACATTATGGACCGGACTCTGCTGC 394 137 2765 Antisense
CCTCTGGACTTGGCAGACTTGCTCC 142 267 2796 Antisense
TTGGATATTTCCAGTCTGCAGACTC 398 683 2825 Antisense
GGTATCTTTGGATCTCCAACACCTG 384 505 2857 Antisense
GGACGTCTTTAACAACCAATACCAG 586 507 2907 Antisense
TGTTGATCCTTGGCATGCACTTGGT 455 563 3027 Antisense
CGATGTTCCAGGGCTCAAGGTTGTC 35 249 3138 Antisense
AAGGTTGTCAGAGATCTCGTCGATC 207 161 3154 Antisense
TGGTTGAATCAATCTCCAGCCACTG 553 549 3193 Antisense
CAGCTTCAACTGTTCAGGCTACAAC 251 199 3287 Antisense
CTCATCTGCTACTATTACCTTGTCA 173 229 3321 Antisense
Sequence Source Affymetrix Proprietary Database