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[191213_at] serine protease inhibitor

Description F35B12.6 /REP_DB=WormBase Gene ID /WP=CE05805 /TR=Q20014 /GB=CAA98467.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=serine protease inhibitor
Cluster 6grp_highest_10_10 > 18      6grp_high1_10_10 > 80      4grp_highest_8_8 > 57      4grp_high_8_8 > 34      6grp_highest_nonorm > 72      6grp_total > 92      4grp_total > 46      6grp_highest_sub > 04_05      6grp_cgc > 98      6grp_high1_sub > 02_03_04_05      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 552
1 2 3 4 range
A 982.9
(3)
P 		651.5
(-0.7)
P 		445
(-3)
P 		510
(-2.3)
P 		538
B 661.1
(3)
P 		633.5
(2.3)
P 		431.2
(-3)
P 		555.3
(0.2)
P 		230
C 958.9
(3)
P 		678.9
(-0.3)
P 		460.1
(-3)
P 		456.1
(-3)
P 		503
avr 867.6
(3) 		654.6
(-0) 		445.4
(-3) 		507.1
(-2.1) 		422

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 414
1 2 3 4 5 6 range
A 275.4
(-2)
P 		453.9
(0.6)
P 		400.6
(-0.2)
P 		492.3
(1.2)
P 		614.2
(3)
P 		208.3
(-3)
P 		406
B 420
(2.2)
P 		391.9
(1.4)
P 		421.1
(2.3)
P 		338.1
(-0.1)
P 		447.2
(3)
P 		237.8
(-3)
P 		209
C 372.3
(-0.3)
P 		410.1
(0.3)
P 		371.3
(-0.3)
P 		501.9
(1.7)
P 		584.7
(3)
P 		200.1
(-3)
P 		385
avr 355.9
(-0.5) 		418.6
(0.7) 		397.7
(0.3) 		444.1
(1.1) 		548.7
(3) 		215.4
(-3) 		333
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 283
1 2 3 4 range
A 357.9
(3)
P 		141.4
(-1.6)
P 		116.3
(-2.1)
P 		74.7
(-3)
P 		283
B 210.8
(3)
P 		156.5
(0.1)
P 		99.9
(-3)
P 		118.3
(-2)
P 		111
C 317.4
(3)
P 		195.2
(-0)
P 		160.4
(-0.9)
P 		76.9
(-3)
P 		241
avr 295.4
(3) 		164.4
(-0.8) 		125.5
(-2) 		90
(-3) 		205

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 139
1 2 3 4 5 6 range
A 50.8
(-3)
P 		161.4
(1.9)
P 		87.2
(-1.4)
P 		124.9
(0.3)
P 		185.3
(3)
P 		50.7
(-3)
P 		135
B 146.1
(0.7)
P 		130.5
(-0.3)
P 		102.3
(-2.1)
P 		89.6
(-2.9)
P 		181.7
(3)
P 		88.7
(-3)
P 		93
C 138
(0.5)
P 		125.1
(-0.1)
P 		94.5
(-1.6)
P 		100.9
(-1.3)
P 		189.2
(3)
P 		67
(-3)
P 		122
avr 111.6
(-0.8) 		139
(0.6) 		94.7
(-1.7) 		105.1
(-1.1) 		185.4
(3) 		68.8
(-3) 		117
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191213_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14140
Sequence Type Exemplar sequence
Representative Public ID F35B12.6 NCBI
Target Description F35B12.6 /REP_DB=WormBase Gene ID /WP=CE05805 /TR=Q20014 /GB=CAA98467.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=serine protease inhibitor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073544(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073544 NCBI Caenorhabditis elegans Temporarily Assigned Gene name family member (tag-290) (tag-290) mRNA, complete cds. 11/11 None
SNAP00000002154 ENSEMBL cdna:SNAP chromosome:CEL140:V:11615898:11617234:1 11/11 None
GENEFINDER00000002169 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:11615898:11617234:1 11/11 None
F35B12.6 ENSEMBL cdna:known chromosome:CEL140:V:11615896:11617433:1 gene:F35B12.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:11615897-11617234(+) 100.0 100.0
Public Domain and Genome References
Gene Title serine protease inhibitor
Gene Symbol tag-290
Ensembl F35B12.6
Entrez Gene 179593 Entrez gene
SwissProt Q20014 EMBL-EBI
WormBase CE05805 Wormbase
Functional Annotations
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
4867 serine-type endopeptidase inhibitor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA98467 Hypothetical protein F35B12.6 [Caenorhabditis elegans] ref|NP_505945.1| Temporarily Assigned Gene name family member (tag-290) [Caenorhabditis elegans] 1.0E-135
blast CAE75327 Hypothetical protein CBG23305 [Caenorhabditis briggsae] 1.0E-108
blast CAA98461 Hypothetical protein F35B12.4 [Caenorhabditis elegans] ref|NP_505943.1| F35B12.4 [Caenorhabditis elegans] 7.0E-36
Protein Domains
Database ID Description E-Value
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 1.2E-27
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 7.6E-10
Sequence
Target Sequence 
>C. ELEGANS:191213_AT
cttgttcctgtattcagctttgattgtactcaaccaaaggatagtggtaatgtatgtagt
ggaagccaagcagaaagatctttttattttgataccagaatgaaagtatgtcaaccattc
ctgtattctggttgtggtggaaatgaaaataggttttcaacatcgaaagaatgtagagat
gcctgtcaaaataagaaatcatcttcaacaaccgaatctccagatactatatctgatgat
tccgctgatcaatccggctcaccaaactctccaccatttgtaccacaaggagatgggcac
gatcaatggagaaaagcagatatttgtggttcaaactatttgattccaaatggaaaatat
atcacttgctctccaaatcaagcttgcccaaaattccattcatgtgttaacggagcatgt
tgcccttcaaaagactacgtttgctctttaagagatgataatggaagttttatggacgga
gttgaagatcgtccaagattctcat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CTTGTTCCTGTATTCAGCTTTGATT 221 219 43 Antisense
GTATGTCAACCATTCCTGTATTCTG 704 455 148 Antisense
TCATCTTCAACAACCGAATCTCCAG 37 621 241 Antisense
TGATGATTCCGCTGATCAATCCGGC 116 567 276 Antisense
TCACCAAACTCTCCACCATTTGTAC 295 623 301 Antisense
GAAAATATATCACTTGCTCTCCAAA 452 353 395 Antisense
TTGCTCTCCAAATCAAGCTTGCCCA 243 703 408 Antisense
AGCTTGCCCAAAATTCCATTCATGT 306 79 423 Antisense
GTTAACGGAGCATGTTGCCCTTCAA 347 445 448 Antisense
GCCCTTCAAAAGACTACGTTTGCTC 236 279 464 Antisense
GTTGAAGATCGTCCAAGATTCTCAT 3 439 523 Antisense
Sequence Source Affymetrix Proprietary Database