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Cluster Members
Consensus/Exemplar

GeneChip Array Information

Probe Set ID

191203_at

GeneChip Array

C. elegans Genome Array

Organism Common Name

Nematode

Probe Design Information

Transcript ID(Array Design)

affy.Ce.12864

Sequence Type

Exemplar sequence

Representative Public ID

F43D2.1 NCBI

Target Description

F43D2.1 /REP_DB=WormBase Gene ID /WP=CE10334 /TR=O17869 /GB=CAB05724.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=G1-S-specfic cyclin C like

Cluster Evidence

This cluster is supported by a Sanger Annotation.

Annotation Method Description

Annotation Description

This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).

Annotation Grade

This is a grade A annotation.

Annotation Transcript Cluster (# of Matching Probes)

NM_074214(11)

Transcript Assignments

Representative Transcript	Description	Matching Probes	Related Probesets by Grade
NM_074214 NCBI	Caenorhabditis elegans F43D2.1 (F43D2.1) mRNA, complete cds.	11/11	None
SNAP00000010906 ENSEMBL	cdna:SNAP chromosome:CEL140:V:14615234:14616178:1	11/11	None
GENEFINDER00000010920 ENSEMBL	cdna:GeneFinder chromosome:CEL140:V:14615234:14616178:1	11/11	None
F43D2.1 ENSEMBL	cdna:known chromosome:CEL140:V:14615146:14616178:1 gene:F43D2.1	11/11	None

Annotation Notes

There are no noteworthy cross hybridizing mRNAs found for this probe set.

Genomic Alignment of Consensus/Exemplar Sequence

Assembly

Wormbase March 2004

Alignment(s)

Position	Identity	Coverage	Cytoband
chrV:14615145-14616178(+)	100.0	100.0

Public Domain and Genome References

Gene Title

G1/S-specfic cyclin C like

Ensembl

F43D2.1

Entrez Gene

185704 Entrez gene

SwissProt

O17869 EMBL-EBI

WormBase

CE38186 Wormbase

Functional Annotations

Ortholog

ID	Title	Organism
CANINE_2:CFAAFFX.27281.1.S1_AT	similar to cyclin K	cfa
CANINE_2:CFAAFFX.27285.1.S1_S_AT	similar to cyclin K	cfa
DROSOPHILA_2:1634262_S_AT	Cyclin K	dm
DROSGENOME1:154047_AT	Cyclin K	dm
CHICKEN:GGAAFFX.12009.1.S1_S_AT	cyclin K	gga
CHICKEN:GGAAFFX.7070.1.S1_S_AT	cyclin K	gga
HU35KSUBB:RC_N56993_AT	cyclin K	hs
HG-U133A:219273_AT	cyclin K	hs
HG-U133_PLUS_2:219273_AT	cyclin K	hs
HG-FOCUS:219273_AT	cyclin K	hs
HG-U133A_2:219273_AT	cyclin K	hs
U133_X3P:HS.12186.1.A1_3P_AT	cyclin K	hs
HG-U133_PLUS_2:225824_AT	cyclin K	hs
HG-U133B:225824_AT	cyclin K	hs
HG-U95D:82219_AT	cyclin K	hs
HG-U95E:90627_AT	cyclin K	hs
HG-U95E:91009_AT	cyclin K	hs
HG-U95E:91012_G_AT	cyclin K	hs
MOUSE430A_2:1424830_AT	cyclin K	mm
MOE430A:1424830_AT	cyclin K	mm
MOUSE430_2:1424830_AT	cyclin K	mm
MG-U74BV2:116962_AT	cyclin K	mm
MU19KSUBA:TC24266_AT	Cyclin K, mRNA (cDNA clone MGC:28173 IMAGE:3986609)	mm
MU19KSUBA:TC24266_G_AT	Cyclin K, mRNA (cDNA clone MGC:28173 IMAGE:3986609)	mm
RAE230B:1377673_AT	Similar to cyclin K	rn
RAT230_2:1377673_AT	Similar to cyclin K	rn
RG-U34B:RC_AI030661_AT	Similar to cyclin K	rn
RG-U34C:RC_AI176055_AT	Similar to cyclin K	rn

Protein Similarities

Method	ID	Description	E-Value
blast	CAB05724	Hypothetical protein F43D2.1 [Caenorhabditis elegans] ref\|NP_506615.2\| F43D2.1 [Caenorhabditis elegans]	1.0E-147
blast	CAB05724	Hypothetical protein F43D2.1 [Caenorhabditis elegans] ref\|NP_506615.2\| F43D2.1 [Caenorhabditis elegans]	1.0E-145
blast	CAB05724	Hypothetical protein F43D2.1 [Caenorhabditis elegans] ref\|NP_506615.2\| F43D2.1 [Caenorhabditis elegans]	1.0E-139
blast	CAE60863	Hypothetical protein CBG04574 [Caenorhabditis briggsae]	1.0E-122
blast	CAE60863	Hypothetical protein CBG04574 [Caenorhabditis briggsae]	1.0E-120
blast	CAE60863	Hypothetical protein CBG04574 [Caenorhabditis briggsae]	1.0E-117
blast	AAN11147	CG15218-PB, isoform B [Drosophila melanogaster] gb\|AAN11146.1\| CG15218-PA, isoform A [Drosophila melanogaster] ref\|NP_788083.1\| CG15218-PB, isoform B [Drosophila melanogaster] ref\|NP_788082.1\| CG15218-PA, isoform A [Drosophila melanogaster] gb\|AAK93091.1\| LD21709p [Drosophila melanogaster]	9.0E-47
blast	EAL32909	GA13578-PA [Drosophila pseudoobscura]	6.0E-46

Protein Domains

Database	ID	Description	E-Value
Pfam	IPR006671 EMBL-EBI	Cyclin, N-terminal domain	6.3E-10
Pfam	IPR006671 EMBL-EBI	Cyclin, N-terminal domain	6.3E-10
Pfam	IPR006671 EMBL-EBI	Cyclin, N-terminal domain	6.3E-10

Sequence

Target Sequence

>C. ELEGANS:191203_AT
ccccactatcggtgttgcagctgtatattttcatcggttttatatgattcacagtttcca
gtcattcagtcgagaggtaactgcactaagctgtttgtttttggctggaaaagtcgaaga
tttcccgaaaaaatgcaaagatgtttgtcaagcggctgtgactcattatccagaaattta
ttcaaagtaccagaaccttgtggacgatgtaatggggctggaaagagtactgttgcacag
tcttaaatttgacttgcatgttgctttgccgtacgatgctttgctggattataagatgat
gtttccagatatgaatcgtgagaagattaccgacgccgttcaaatagcttggacattcat
caacgacagcatctacaccacattgtgcattaccacggagccacaaatgattgcaatagc
acttttacatcttgcgttcactgtaaaaggatatcagcctgttcagaagaatatggatcc
atgttggtggtcagcggatgttagtaattggcctcaagaatcagttgacaaggcatgtca
tctggtgctagatttctacgctgctacta

BLASTn GenBank NR

Probe Info

Probe Sequence(5'-3')	Probe X	Probe Y	Probe Interrogation Position	Strandedness
CCCCACTATCGGTGTTGCAGCTGTA	553	259	177	Antisense
GATTCACAGTTTCCAGTCATTCAGT	143	431	222	Antisense
TCAAGCGGCTGTGACTCATTATCCA	407	631	324	Antisense
TGACTTGCATGTTGCTTTGCCGTAC	153	571	426	Antisense
TTTGCCGTACGATGCTTTGCTGGAT	460	669	441	Antisense
TACCGACGCCGTTCAAATAGCTTGG	331	647	504	Antisense
GACAGCATCTACACCACATTGTGCA	337	369	541	Antisense
ACATTGTGCATTACCACGGAGCCAC	687	103	556	Antisense
AGCACTTTTACATCTTGCGTTCACT	48	71	594	Antisense
GACAAGGCATGTCATCTGGTGCTAG	287	365	703	Antisense
GTGCTAGATTTCTACGCTGCTACTA	700	479	721	Antisense

Sequence Source

Affymetrix Proprietary Database

Description	F43D2.1 /REP_DB=WormBase Gene ID /WP=CE10334 /TR=O17869 /GB=CAB05724.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=G1-S-specfic cyclin C like
Cluster	6grp_highest_10_10 > 89 6grp_high1_10_10 > 98 4grp_highest_8_8 > 47 4grp_high_8_8 > 12 6grp_highest_nonorm > 78 6grp_total > 95 4grp_total > 13 6grp_highest_sub > In 6grp_high1_sub > In 6grp_total_sub > Increase