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[191189_at] lariat debranching enzyme

Description C55B7.8 /REP_DB=WormBase Gene ID /WP=CE09019 /GEN=dbr-1 /GB=AAK68279.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=lariat debranching enzyme
Cluster 6grp_highest_10_10 > 67      6grp_high1_10_10 > 76      4grp_highest_8_8 > 37      4grp_high_8_8 > 03      6grp_highest_nonorm > 83      6grp_total > 66      4grp_total > 07      6grp_highest_sub > In      6grp_cgc > 47      6grp_high1_sub > Da      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 395
1 2 3 4 range
A 459
(-1.1)
P 		499.1
(-0.2)
P 		372.5
(-3)
P 		643.4
(3)
P 		271
B 632.2
(3)
P 		323.4
(-3)
P 		501.4
(0.5)
P 		563.5
(1.7)
P 		309
C 482.3
(0.9)
P 		248.8
(-3)
P 		443.7
(0.2)
P 		609.7
(3)
P 		361
avr 524.5
(1) 		357.1
(-3) 		439.2
(-1) 		605.5
(3) 		248

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 500
1 2 3 4 5 6 range
A 426.2
(-1.2)
P 		378.7
(-2.5)
P 		475.3
(0.1)
P 		360.2
(-3)
P 		581.4
(3)
P 		557.7
(2.4)
P 		221
B 386.4
(-2.4)
P 		369.7
(-2.8)
P 		434.2
(-1.4)
P 		358.2
(-3)
P 		418
(-1.8)
P 		645.3
(3)
P 		287
C 255.5
(-3)
P 		469
(-0.4)
P 		481.8
(-0.3)
P 		386.4
(-1.4)
P 		288.9
(-2.6)
P 		755.1
(3)
P 		500
avr 356
(-3) 		405.8
(-2) 		463.8
(-0.8) 		368.3
(-2.8) 		429.4
(-1.5) 		652.7
(3) 		297
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 130
1 2 3 4 range
A 167.1
(3)
P 		108.3
(-1.8)
P 		97.4
(-2.7)
P 		94.2
(-3)
P 		73
B 201.6
(3)
P 		79.9
(-3)
P 		116.2
(-1.2)
P 		120.1
(-1)
P 		122
C 159.6
(3)
P 		71.5
(-3)
P 		154.6
(2.7)
P 		102.8
(-0.9)
P 		88
avr 176.1
(3) 		86.6
(-3) 		122.7
(-0.6) 		105.7
(-1.7) 		90

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 175
1 2 3 4 5 6 range
A 78.6
(-3)
P 		134.7
(0.5)
P 		103.5
(-1.5)
P 		91.4
(-2.2)
P 		175.4
(3)
P 		135.8
(0.5)
P 		97
B 134.4
(-1.4)
P 		123.1
(-1.8)
P 		105.4
(-2.6)
P 		94.9
(-3)
P 		169.8
(0.1)
P 		240.6
(3)
P 		146
C 94.7
(-2.4)
P 		143.1
(-0.8)
P 		122.6
(-1.5)
P 		77.7
(-3)
P 		93.5
(-2.5)
P 		252.8
(3)
P 		175
avr 102.6
(-2.3) 		133.6
(-0.8) 		110.5
(-1.9) 		88
(-3) 		146.2
(-0.1) 		209.7
(3) 		122
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191189_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1613
Sequence Type Exemplar sequence
Representative Public ID C55B7.8 NCBI
Target Description C55B7.8 /REP_DB=WormBase Gene ID /WP=CE09019 /GEN=dbr-1 /GB=AAK68279.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=lariat debranching enzyme
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059467(9)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059467 NCBI Caenorhabditis elegans lariat DeBRanching enzyme related family member (dbr-1) (dbr-1) mRNA, complete cds. 9/11 None
SNAP00000038298 ENSEMBL cdna:SNAP chromosome:CEL140:I:6499004:6500861:-1 11/11 None
GENEFINDER00000038308 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:6499004:6500861:-1 9/11 None
C55B7.8 ENSEMBL cdna:known chromosome:CEL140:I:6498853:6500862:-1 gene:C55B7.8 9/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:6498932-6500790(-) 100.0 100.0
Public Domain and Genome References
Gene Title lariat debranching enzyme
Gene Symbol dbr-1
Ensembl C55B7.8
Entrez Gene 172357 Entrez gene
SwissProt Q966M6 EMBL-EBI
WormBase CE30437 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:253491_AT calcineurin-like phosphoesterase family protein at
CANINE_2:CFA.21153.1.S1_AT similar to debranching enzyme homolog 1 cfa
CANINE_2:CFA.21153.2.S1_S_AT similar to debranching enzyme homolog 1 cfa
CANINE_2:CFAAFFX.12126.1.S1_AT similar to debranching enzyme homolog 1 cfa
DROSOPHILA_2:1626571_AT dm
DROSGENOME1:153801_AT dm
CHICKEN:GGAAFFX.11815.1.S1_AT debranching enzyme homolog 1 (S. cerevisiae) gga
CHICKEN:GGAAFFX.787.1.S1_S_AT debranching enzyme homolog 1 (S. cerevisiae) gga
HG-U133A:219149_X_AT debranching enzyme homolog 1 (S. cerevisiae) hs
HG-U133_PLUS_2:219149_X_AT debranching enzyme homolog 1 (S. cerevisiae) hs
HG-FOCUS:219149_X_AT debranching enzyme homolog 1 (S. cerevisiae) hs
HG-U133A_2:219149_X_AT debranching enzyme homolog 1 (S. cerevisiae) hs
U133_X3P:G7705890_3P_A_AT debranching enzyme homolog 1 (S. cerevisiae) hs
U133_X3P:HS.118194.1.S1_3P_AT debranching enzyme homolog 1 (S. cerevisiae) hs
HG-U133_PLUS_2:234295_AT debranching enzyme homolog 1 (S. cerevisiae) hs
HG-U133B:234295_AT debranching enzyme homolog 1 (S. cerevisiae) hs
HG-U95E:74994_AT debranching enzyme homolog 1 (S. cerevisiae) hs
HG-U95E:76186_R_AT debranching enzyme homolog 1 (S. cerevisiae) hs
MOE430A:1451641_AT debranching enzyme homolog 1 (S. cerevisiae) mm
MOUSE430A_2:1451641_AT debranching enzyme homolog 1 (S. cerevisiae) mm
MOUSE430_2:1451641_AT debranching enzyme homolog 1 (S. cerevisiae) mm
MG-U74BV2:113720_AT debranching enzyme homolog 1 (S. cerevisiae) mm
MU19KSUBC:TC41820_AT Debranching enzyme homolog 1 (S. cerevisiae) (Dbr1), mRNA mm
RAE230B:1393701_AT similar to Alpha-1,4-N-acetylglucosaminyltransferase (Alpha4GnT) (predicted) rn
RAT230_2:1393701_AT similar to Alpha-1,4-N-acetylglucosaminyltransferase (Alpha4GnT) (predicted) rn
YEAST_2:1771880_AT RNA lariat debranching enzyme, involved in intron turnover; required for efficient Ty1 transposition Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6397 mRNA processing inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16787 hydrolase activity inferred from electronic annotation QuickGO AmiGO
16788 hydrolase activity, acting on ester bonds inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_491868 lariat DeBRanching enzyme related family member (dbr-1) [Caenorhabditis elegans] gb|AAK68279.2| Lariat debranching enzyme related protein 1 [Caenorhabditis elegans] gb|AAC47433.1| RNA lariat debranching enzyme 0.0
blast CAE67205 Hypothetical protein CBG12641 [Caenorhabditis briggsae] 0.0
blast AAH53153 Debranching enzyme homolog 1 [Danio rerio] ref|NP_955947.1| debranching enzyme homolog 1 [Danio rerio] 8.0E-91
Protein Domains
Database ID Description E-Value
Pfam IPR004843 EMBL-EBI Metallo-phosphoesterase 8.7E-15
Pfam IPR007708 EMBL-EBI Lariat debranching enzyme, C-terminal 3.3E-96
Pfam IPR007708 EMBL-EBI Lariat debranching enzyme, C-terminal 8.3E-93
Sequence
Target Sequence 
>C. ELEGANS:191189_AT
tttatgcaggcaagtcgtcacgctctcgagttgaatgttgcagacgatgctaaactggaa
ctgtcatatgatccacaatggttggctattctgagaaatacagatttattaacaactgga
acaaaagaacagctgatacttcccgatatggcatcaaatcgtccatgtgtctacgaaaga
aaagattttcgaccaacagcagaggagttaaaagaaatcgaaaaactcggagatttaaca
atcagaactgacagtttccaacaaactgcgcctccgttaaaagagattacggaatcatcc
aaaaatgtgccaccaagcgcctactaccgtaatccacaatctgccgagttttgtcagtgg
cttggtattcgggatcttaatcagatgctcgttgaaaaaacatctgaacacgttggaact
ccgtactacatgatgactcaagacgatgcgaacgctaaaccaaatcaagatgacgtggat
tttggtgacgaagattttgtaatcgacagagggcacacctccgatga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTTATGCAGGCAAGTCGTCACGCTC 201 673 940 Antisense
GTCGTCACGCTCTCGAGTTGAATGT 517 473 953 Antisense
GATCCACAATGGTTGGCTATTCTGA 68 415 1009 Antisense
GAACAGCTGATACTTCCCGATATGG 599 351 1066 Antisense
GGCATCAAATCGTCCATGTGTCTAC 343 537 1089 Antisense
ACAAACTGCGCCTCCGTTAAAAGAG 29 105 1200 Antisense
CCAAAAATGTGCCACCAAGCGCCTA 553 275 1238 Antisense
CGTAATCCACAATCTGCCGAGTTTT 232 247 1267 Antisense
GTCAGTGGCTTGGTATTCGGGATCT 565 465 1292 Antisense
GAACACGTTGGAACTCCGTACTACA 443 351 1345 Antisense
TCGACAGAGGGCACACCTCCGATGA 577 599 1442 Antisense
Sequence Source Affymetrix Proprietary Database