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[191187_at] nuclear hormone receptor

Description C33G8.12 /REP_DB=WormBase Gene ID /WP=CE17498 /TR=Q18392 /GB=AAC25856.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=nuclear hormone receptor
Cluster 6grp_highest_10_10 > 24      6grp_high1_10_10 > 30      4grp_highest_8_8 > 55      4grp_high_8_8 > 19      6grp_highest_nonorm > 90      6grp_total > 41      4grp_total > 29      6grp_cgc > 82      6grp_high1_sub > 03      6grp_cgc_sub > 03      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 80
1 2 3 4 range
A 94.8
(1.5)
P 		105.5
(3)
P 		61.9
(-3)
P 		73.8
(-1.4)
P 		44
B 79.5
(3)
P 		48.9
(-1.6)
P 		39.9
(-3)
P 		66.2
(1)
P 		40
C 67.6
(-3)
P 		70.4
(-2.7)
P 		72.3
(-2.5)
P 		119.8
(3)
P 		52
avr 80.6
(1.7) 		74.9
(0.5) 		58
(-3) 		86.6
(3) 		29

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 110
1 2 3 4 5 6 range
A 65.1
(-1.7)
P 		83.2
(-0.8)
P 		151.8
(3)
P 		125.1
(1.5)
P 		42.1
(-3)
P 		67.4
(-1.6)
P 		110
B 120.5
(3)
P 		107
(1.7)
P 		108.4
(1.8)
P 		83.5
(-0.6)
P 		58
(-3)
P 		66.4
(-2.2)
P 		63
C 109
(1.5)
P 		113.8
(1.9)
P 		126.8
(3)
P 		71.6
(-1.6)
P 		55.4
(-3)
P 		98.9
(0.7)
P 		71
avr 98.2
(0.6) 		101.3
(0.8) 		129
(3) 		93.4
(0.2) 		51.8
(-3) 		77.6
(-1) 		77
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 25
1 2 3 4 range
A 34.5
(3)
P 		22.9
(0.1)
P 		16.2
(-1.6)
P 		10.8
(-3)
P 		24
B 25.3
(3)
P 		12.1
(-2)
P 		9.3
(-3)
P 		14.1
(-1.2)
P 		16
C 22.4
(-0.4)
P 		20.3
(-2.9)
P 		25.2
(3)
P 		20.2
(-3)
P 		5
avr 27.4
(3) 		18.4
(-1.4) 		16.9
(-2.1) 		15
(-3) 		12

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 30
1 2 3 4 5 6 range
A 12
(-3)
P 		29.6
(2)
P 		33.1
(3)
P 		31.7
(2.6)
P 		12.7
(-2.8)
P 		16.4
(-1.7)
P 		21
B 41.9
(3)
P 		35.6
(1.1)
P 		26.3
(-1.7)
P 		22.1
(-3)
P 		23.6
(-2.5)
P 		24.8
(-2.2)
P 		20
C 40.4
(3)
P 		34.7
(1.7)
P 		32.3
(1.1)
P 		14.4
(-3)
P 		17.9
(-2.2)
P 		33.1
(1.3)
P 		26
avr 31.4
(2.3) 		33.3
(3) 		30.6
(1.9) 		22.7
(-1.2) 		18.1
(-3) 		24.8
(-0.4) 		15
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191187_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11768
Sequence Type Exemplar sequence
Representative Public ID C33G8.12 NCBI
Target Description C33G8.12 /REP_DB=WormBase Gene ID /WP=CE17498 /TR=Q18392 /GB=AAC25856.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=nuclear hormone receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072365(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072365 NCBI Caenorhabditis elegans C33G8.12 (C33G8.12) mRNA, complete cds. 11/11 None
SNAP00000000528 ENSEMBL cdna:SNAP chromosome:CEL140:V:6986004:6990348:-1 11/11 None
GENEFINDER00000000543 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:6983240:6987381:-1 10/11 None
C33G8.12 ENSEMBL cdna:known chromosome:CEL140:V:6986004:6988636:-1 gene:C33G8.12 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:6986004-6988637(-) 100.0 100.0
Public Domain and Genome References
Gene Title nuclear hormone receptor
Gene Symbol nhr-163
Ensembl C33G8.12
Entrez Gene 183182 Entrez gene
SwissProt Q18392 EMBL-EBI
WormBase CE17498 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3700 transcription factor activity inferred from electronic annotation QuickGO AmiGO
3707 steroid hormone receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC25856 Hypothetical protein C33G8.12 [Caenorhabditis elegans] ref|NP_504766.1| C33G8.12 [Caenorhabditis elegans] 0.0
blast AAC25852 Hypothetical protein C33G8.8 [Caenorhabditis elegans] ref|NP_504767.1| C33G8.8 [Caenorhabditis elegans] 0.0
blast AAC25854 Hypothetical protein C33G8.7 [Caenorhabditis elegans] ref|NP_504765.1| C33G8.7 [Caenorhabditis elegans] 1.0E-178
blast AAC25856 Hypothetical protein C33G8.12 [Caenorhabditis elegans] ref|NP_504766.1| C33G8.12 [Caenorhabditis elegans] 1.0E-175
blast AAC25856 Hypothetical protein C33G8.12 [Caenorhabditis elegans] ref|NP_504766.1| C33G8.12 [Caenorhabditis elegans] 1.0E-148
blast AAN84868 Nuclear hormone receptor family protein 94, isoform a [Caenorhabditis elegans] ref|NP_504989.2| Nuclear Hormone Receptor family member (nhr-94) [Caenorhabditis elegans] gb|AAO39186.1| nuclear receptor NHR-94 [Caenorhabditis elegans] 1.0E-137
blast AAC25852 Hypothetical protein C33G8.8 [Caenorhabditis elegans] ref|NP_504767.1| C33G8.8 [Caenorhabditis elegans] 1.0E-116
blast AAC25853 Hypothetical protein C33G8.10 [Caenorhabditis elegans] ref|NP_504769.1| C33G8.10 [Caenorhabditis elegans] 1.0E-104
Protein Domains
Database ID Description E-Value
Pfam IPR000536 EMBL-EBI Ligand-binding domain of nuclear hormone receptor 1.2E-5
Pfam IPR000536 EMBL-EBI Ligand-binding domain of nuclear hormone receptor 1.2E-5
Pfam IPR000536 EMBL-EBI Ligand-binding domain of nuclear hormone receptor 1.7E-4
Pfam IPR000536 EMBL-EBI Ligand-binding domain of nuclear hormone receptor 8.2E-7
Pfam IPR001628 EMBL-EBI Zn-finger, C4-type steroid receptor 6.7E-11
Sequence
Target Sequence 
>C. ELEGANS:191187_AT
tattctcggatgtatctcgattgagtaaagaagacaaaaactcaatgatttcaaactttt
atatcaaatggcaacttctcatggaaccggcaatagactactcagctcagtatgaacaat
ttaaaaattacatcgggtcaaatgcatactaccaaaagtgtgcttacttttatggaagtt
caatgcaaaaaggaaataaaatttctgatgtggagactgtcaaagtattttctccatttt
gggactactattacgcagattttgctgaaccagtttataaaatgaactacgacaaagtgg
aatatatggctatatttcttctactgttgtttgacggcgcgtactcagatattagtgacg
atggcgtgaacttgtgtacaaatattcgaaaagtaatactacgggaattgaacagttatc
aatcgaataacaattgctcagaagttcgtctagctgatataatggaaactcttcgattgt
tggataaacatgaggaaaagctacactatcaattttggatgtgcgggtctcata

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TATTCTCGGATGTATCTCGATTGAG 485 663 503 Antisense
AAATGGCAACTTCTCATGGAACCGG 552 117 568 Antisense
GAACCGGCAATAGACTACTCAGCTC 244 347 586 Antisense
GTATTTTCTCCATTTTGGGACTACT 404 453 727 Antisense
GGGACTACTATTACGCAGATTTTGC 322 495 743 Antisense
ATGGCTATATTTCTTCTACTGTTGT 425 53 808 Antisense
TCTACTGTTGTTTGACGGCGCGTAC 175 611 822 Antisense
GACGGCGCGTACTCAGATATTAGTG 213 377 835 Antisense
GACGATGGCGTGAACTTGTGTACAA 548 377 859 Antisense
AATTGCTCAGAAGTTCGTCTAGCTG 564 177 934 Antisense
CAATTTTGGATGTGCGGGTCTCATA 299 181 1012 Antisense
Sequence Source Affymetrix Proprietary Database