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[191180_at] warthog gene

Description ZK1290.12 /REP_DB=WormBase Gene ID /WP=CE15545 /GEN=wrt-1 /TR=Q94128 /GB=AAB93321.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=warthog gene
Cluster 6grp_highest_10_10 > 44      6grp_high1_10_10 > 43      6grp_highest_nonorm > 43      6grp_total > 20      4grp_total > 49      6grp_highest_sub > 02      6grp_cgc > 63      6grp_high1_sub > 02      6grp_cgc_sub > 02      6grp_total_sub > Hat      6grp_rule_based > S2      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 3257
1 2 3 4 range
A 22.9
(-3)
A 		3280.2
(3)
P 		3145.4
(2.8)
P 		137.4
(-2.8)
A 		3257
B 59.7
(-3)
A 		2782.9
(2.2)
P 		3216.1
(3)
P 		105.9
(-2.9)
A 		3156
C 43.2
(-3)
A 		2884.3
(3)
P 		2885
(3)
P 		127
(-2.8)
A 		2842
avr 41.9
(-3) 		2982.5
(2.8) 		3082.2
(3) 		123.4
(-2.8) 		3040

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1778
1 2 3 4 5 6 range
A 645.1
(-2.7)
P 		2113.9
(3)
P 		1255.7
(-0.3)
P 		1165.1
(-0.7)
P 		901.3
(-1.7)
P 		554.4
(-3)
P 		1560
B 466.9
(-3)
P 		1814.4
(3)
P 		1291.4
(0.7)
P 		1258.8
(0.5)
P 		681.2
(-2)
P 		468.2
(-3)
P 		1348
C 336.1
(-3)
P 		1833.4
(3)
P 		1306.9
(0.9)
P 		1314.3
(0.9)
P 		698.7
(-1.5)
P 		555.8
(-2.1)
P 		1497
avr 482.7
(-3) 		1920.6
(3) 		1284.7
(0.3) 		1246.1
(0.2) 		760.4
(-1.8) 		526.1
(-2.8) 		1438
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 997
1 2 3 4 range
A 8.3
(-3)
A 		712
(2.2)
P 		822.3
(3)
P 		20.1
(-2.9)
A 		814
B 19
(-3)
A 		687.3
(2.5)
P 		745.2
(3)
P 		22.6
(-3)
A 		726
C 14.3
(-3)
A 		829.2
(1.9)
P 		1005.5
(3)
P 		21.4
(-3)
A 		991
avr 13.9
(-3) 		742.8
(2.2) 		857.7
(3) 		21.4
(-2.9) 		844

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 633
1 2 3 4 5 6 range
A 118.9
(-3)
P 		751.8
(3)
P 		273.5
(-1.5)
P 		295.5
(-1.3)
P 		272
(-1.5)
P 		135
(-2.8)
P 		633
B 162.4
(-3)
P 		603.9
(3)
P 		313.6
(-0.9)
P 		333.4
(-0.7)
P 		276.8
(-1.4)
P 		174.6
(-2.8)
P 		442
C 124.6
(-3)
P 		559.4
(3)
P 		332.6
(-0.1)
P 		264.3
(-1.1)
P 		226.1
(-1.6)
P 		186.1
(-2.2)
P 		435
avr 135.3
(-3) 		638.4
(3) 		306.6
(-1) 		297.7
(-1.1) 		258.3
(-1.5) 		165.2
(-2.6) 		503
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191180_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.4902
Sequence Type Exemplar sequence
Representative Public ID ZK1290.12 NCBI
Target Description ZK1290.12 /REP_DB=WormBase Gene ID /WP=CE15545 /GEN=wrt-1 /TR=Q94128 /GB=AAB93321.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=warthog gene
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063178(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063178 NCBI Caenorhabditis elegans WaRThog (hedgehog-like family) family member (wrt-1) (wrt-1) mRNA, complete cds. 11/11 None
SNAP00000002671 ENSEMBL cdna:SNAP chromosome:CEL140:II:7529569:7533063:1 11/11 None
GENEFINDER00000002688 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:7529569:7533063:1 11/11 None
ZK1290.12 ENSEMBL cdna:known chromosome:CEL140:II:7531079:7533164:1 gene:ZK1290.12 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:7531102-7533060(+) 100.0 100.0
Public Domain and Genome References
Gene Title warthog gene
Gene Symbol wrt-1
Ensembl ZK1290.12
Entrez Gene 174223 Entrez gene
SwissProt Q94128 EMBL-EBI
WormBase CE15545 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
7154 cell communication inferred from electronic annotation QuickGO AmiGO
7275 development inferred from electronic annotation QuickGO AmiGO
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8233 peptidase activity inferred from electronic annotation QuickGO AmiGO
16829 lyase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB93321 Warthog (hedgehog-like family) protein 1 [Caenorhabditis elegans] ref|NP_495579.3| WaRThog (hedgehog-like family) family member (wrt-1) [Caenorhabditis elegans] 0.0
blast Q94128 Warthog protein 1 precursor [Contains: Warthog protein 1 N-product; Warthog protein 1 C-product] gb|AAB17540.1| ZK [Caenorhabditis elegans] 0.0
blast CAE67482 Hypothetical protein CBG12986 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001395 EMBL-EBI Aldo/keto reductase 5.4E-81
Pfam IPR001767 EMBL-EBI Peptidase C46, hedgehog protein, hint region 9.7E-35
Pfam IPR001395 EMBL-EBI Aldo/keto reductase 1.4E-81
Pfam IPR001767 EMBL-EBI Peptidase C46, hedgehog protein, hint region 9.7E-35
Pfam IPR001767 EMBL-EBI Peptidase C46, hedgehog protein, hint region 9.7E-35
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000002688 2 341-363,416-438
Sequence
Target Sequence 
>C. ELEGANS:191180_AT
attatccagttgcttccggagttccagcctgctttactggaaattcaaaggttatgactc
cagcaggagaaaagtcaatggctgatttgagtgttggagatatggttatgacttatgagt
atggaaagatgacatacacaagagttgcatcatggcttcatagactcccagatacaaaag
ctgccttcatcaagctcactactgagcaaggagctattatcgatatgactccgcagcatt
tcatctacaaggctaactgcgttacagaagaaatggaacttgtgtatgctgaggatatga
ccattggggattgtctgatggtgaaggaaaatgaaaaactcgtgatgacaactatcagtg
aaaaatcaacattttacgagactggagtgtacgctccaatgactgaaactggagatttaa
ttgttgatgacgtgtatgcttcatgtcacaatgttgtcaaggctaacacattatctcata
ctttcctcaacttcgccacttccgttcaacaaaagatgcgatcagttcttggatcattag
aagaaactgggcatcttccagccacttctgaattcttct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATTATCCAGTTGCTTCCGGAGTTCC 492 13 851 Antisense
GGAGTTCCAGCCTGCTTTACTGGAA 334 517 868 Antisense
GCATCATGGCTTCATAGACTCCCAG 339 309 997 Antisense
AAAAGCTGCCTTCATCAAGCTCACT 101 133 1026 Antisense
TATGACTCCGCAGCATTTCATCTAC 85 657 1074 Antisense
GTGTACGCTCCAATGACTGAAACTG 502 483 1237 Antisense
GACGTGTATGCTTCATGTCACAATG 87 377 1279 Antisense
AACACATTATCTCATACTTTCCTCA 557 135 1315 Antisense
TTCGCCACTTCCGTTCAACAAAAGA 289 697 1342 Antisense
AAGAAACTGGGCATCTTCCAGCCAC 635 151 1391 Antisense
CTTCCAGCCACTTCTGAATTCTTCT 319 219 1405 Antisense
Sequence Source Affymetrix Proprietary Database