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[191141_at] protein kinase

Description T10H9.2 /REP_DB=WormBase Gene ID /WP=CE18250 /GEN=scd-2 /TR=O76411 /GB=AAC19236.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=protein kinase
Cluster 6grp_high1_10_10 > 02      6grp_total > 25      4grp_total > 39      6grp_cgc > 24      6grp_high1_sub > De      6grp_cgc_sub > Cu      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 488
1 2 3 4 range
A 714.9
(3)
P 		313.7
(-2.7)
A 		293.6
(-3)
A 		368.8
(-1.9)
P 		421
B 625.4
(3)
P 		271
(-2.3)
A 		226.9
(-3)
A 		417.5
(-0.1)
P 		399
C 633.3
(3)
P 		378.1
(-1.2)
A 		271.3
(-3)
A 		398.4
(-0.9)
P 		362
avr 657.9
(3) 		320.9
(-2.1) 		263.9
(-3) 		394.9
(-1) 		394

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 352
1 2 3 4 5 6 range
A 558.1
(3)
P 		500.6
(2)
P 		205.9
(-3)
A 		270.3
(-1.9)
M 		277.8
(-1.8)
P 		353.6
(-0.5)
P 		352
B 493.2
(3)
P 		425.9
(1.3)
P 		368.1
(-0.1)
A 		311.1
(-1.5)
A 		250.2
(-3)
M 		279.2
(-2.3)
P 		243
C 508.5
(3)
P 		456.6
(1.7)
P 		452.9
(1.6)
P 		420.3
(0.9)
P 		261.5
(-3)
A 		305.7
(-1.9)
P 		247
avr 519.9
(3) 		461
(1.6) 		342.3
(-1.2) 		333.9
(-1.3) 		263.2
(-3) 		312.8
(-1.8) 		257
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 208
1 2 3 4 range
A 260.3
(3)
P 		68.1
(-2.6)
A 		76.7
(-2.3)
A 		54
(-3)
P 		206
B 199.4
(3)
P 		66.9
(-2.4)
A 		52.6
(-3)
A 		89
(-1.5)
P 		147
C 209.6
(3)
P 		108.7
(-1.3)
A 		94.5
(-1.8)
A 		67.2
(-3)
P 		142
avr 223.1
(3) 		81.2
(-2.6) 		74.6
(-2.8) 		70.1
(-3) 		153

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 144
1 2 3 4 5 6 range
A 102.9
(-0.4)
P 		178.1
(3)
P 		44.8
(-3)
A 		68.6
(-1.9)
M 		83.8
(-1.2)
P 		86.1
(-1.1)
P 		133
B 171.6
(3)
P 		141.8
(1)
P 		89.4
(-2.5)
A 		82.4
(-3)
A 		101.6
(-1.7)
M 		104.1
(-1.5)
P 		89
C 188.5
(3)
P 		139.3
(0.2)
P 		115.3
(-1.2)
P 		84.5
(-3)
P 		84.6
(-3)
A 		102.3
(-2)
P 		104
avr 154.3
(3) 		153.1
(2.9) 		83.2
(-2.6) 		78.5
(-3) 		90
(-2.1) 		97.5
(-1.5) 		76
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191141_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11705
Sequence Type Exemplar sequence
Representative Public ID T10H9.2 NCBI
Target Description T10H9.2 /REP_DB=WormBase Gene ID /WP=CE18250 /GEN=scd-2 /TR=O76411 /GB=AAC19236.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072284(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072284 NCBI Caenorhabditis elegans Suppressor of Constitutive Dauer formation family member (scd-2) (scd-2) mRNA, complete cds. 11/11 None
SNAP00000019214 ENSEMBL cdna:SNAP chromosome:CEL140:V:6635863:6642014:1 11/11 None
GENEFINDER00000019221 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:6635863:6642014:1 11/11 None
T10H9.2 ENSEMBL cdna:known chromosome:CEL140:V:6635863:6642252:1 gene:T10H9.2 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:6635862-6642015(+) 100.0 100.0
Public Domain and Genome References
Gene Title protein kinase
Gene Symbol scd-2
Ensembl T10H9.2
Entrez Gene 179054 Entrez gene
SwissProt O76411 EMBL-EBI
WormBase CE36566 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_504685 Suppressor of Constitutive Dauer formation family member (scd-2) [Caenorhabditis elegans] gb|AAC19236.2| Suppressor of constitutive dauer formation protein 2 [Caenorhabditis elegans] 0.0
blast CAE71919 Hypothetical protein CBG18982 [Caenorhabditis briggsae] 0.0
blast T30107 hypothetical protein F44C4.1 - Caenorhabditis elegans 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 5.1E-58
Pfam IPR000719 EMBL-EBI Protein kinase 5.1E-58
Pfam IPR000719 EMBL-EBI Protein kinase 5.1E-58
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_504685.2 2 7-29,928-950
T10H9.2 2 7-29,928-950
SNAP00000019214 2 7-29,859-881
GENEFINDER00000019221 2 7-29,903-925
Sequence
Target Sequence 
>C. ELEGANS:191141_AT
gtgactgttggaagactgctgcggctgatcgaccaaagtttgtggatgtcgtcgagattt
tccaagacattcaagatgatccggcctctgttggcatgcctttcccaattcatccagccg
ttcgagcaacatttgcacattcgcaatccacgccagtctccgtggagacaccaatgaccg
caatgactgaaatctcactgaacagtacatttacagatgcttctacggtgaaagtatctg
cacaacaagacatgcaggatagaatccaactgcacgaactgatgctaactcgtgagcatc
catacacttcggagctcacatcatatgttgtaaatagtattcgaaaagatctcgcaagag
tccaatatgagaatggattgacatcggttccacaaccagagtacctttcaccggaaaaca
acgacgaatccgttcaattgattcctcaaagtaacactgttactgatcaaaccccaccaa
catctttaattgatttgaatagactcggtgtgcaaaatacgggtccaacactacaccggc
cagactctctgaacttcaacg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGACTGTTGGAAGACTGCTGCGGC 196 483 3653 Antisense
AGACATTCAAGATGATCCGGCCTCT 641 71 3717 Antisense
TCCAGCCGTTCGAGCAACATTTGCA 460 589 3765 Antisense
CATTTGCACATTCGCAATCCACGCC 266 215 3782 Antisense
AATCCACGCCAGTCTCCGTGGAGAC 335 167 3797 Antisense
GGAGACACCAATGACCGCAATGACT 655 517 3816 Antisense
ACTCGTGAGCATCCATACACTTCGG 542 97 3940 Antisense
TACACTTCGGAGCTCACATCATATG 128 643 3955 Antisense
GGTTCCACAACCAGAGTACCTTTCA 415 507 4038 Antisense
CAAACCCCACCAACATCTTTAATTG 156 191 4120 Antisense
CGGCCAGACTCTCTGAACTTCAACG 659 241 4189 Antisense
Sequence Source Affymetrix Proprietary Database