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[191080_s_at] DOCK180 protein

Description C02F4.1 /REP_DB=WormBase Gene ID /WP=CE24779 /GEN=ced-5 /TR=O17758 /GB=CAB61006.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=DOCK180 protein
Cluster 6grp_highest_10_10 > 73      6grp_high1_10_10 > 46      4grp_highest_8_8 > 58      4grp_high_8_8 > 33      6grp_highest_nonorm > 40      6grp_total > 37      4grp_total > 46      6grp_highest_sub > Cu      6grp_cgc > 16      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 511
1 2 3 4 range
A 869.9
(3)
P 		505
(-2.5)
P 		470.6
(-3)
P 		534
(-2)
P 		399
B 729.9
(3)
P 		529.5
(-1.4)
P 		457.9
(-3)
P 		556
(-0.8)
P 		272
C 776.6
(3)
P 		525.5
(-0.6)
P 		466.6
(-1.4)
P 		358.6
(-3)
P 		418
avr 792.1
(3) 		520
(-2) 		465
(-3) 		482.9
(-2.7) 		327

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 503
1 2 3 4 5 6 range
A 795.2
(3)
P 		705.3
(1.1)
P 		527.9
(-2.7)
P 		512.4
(-3)
P 		541
(-2.4)
P 		744.2
(1.9)
P 		283
B 918.8
(3)
P 		706.3
(0.5)
P 		616.4
(-0.6)
P 		618.3
(-0.6)
P 		415.7
(-3)
P 		711.8
(0.5)
P 		503
C 735.9
(3)
P 		713.4
(2.6)
P 		665.6
(1.7)
P 		568.7
(-0.2)
P 		420.2
(-3)
P 		721.8
(2.7)
P 		316
avr 816.6
(3) 		708.3
(1.2) 		603.3
(-0.6) 		566.5
(-1.2) 		459
(-3) 		725.9
(1.5) 		358
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 256
1 2 3 4 range
A 316.7
(3)
P 		109.6
(-2.2)
P 		123
(-1.9)
P 		78.2
(-3)
P 		239
B 232.8
(3)
P 		130.8
(-1.8)
P 		106.1
(-3)
P 		118.5
(-2.4)
P 		127
C 257.1
(3)
P 		151.1
(-0.2)
P 		162.6
(0.1)
P 		60.5
(-3)
P 		197
avr 268.9
(3) 		130.5
(-1.5) 		130.6
(-1.5) 		85.7
(-3) 		183

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 205
1 2 3 4 5 6 range
A 146.6
(-1.6)
P 		250.9
(3)
P 		115
(-3)
P 		130
(-2.3)
P 		163.2
(-0.9)
P 		181.2
(-0.1)
P 		136
B 319.7
(3)
P 		235.1
(0)
P 		149.7
(-3)
P 		163.8
(-2.5)
P 		168.9
(-2.3)
P 		265.4
(1.1)
P 		170
C 272.8
(3)
P 		217.7
(0.9)
P 		169.4
(-0.9)
P 		114.4
(-3)
P 		136
(-2.2)
P 		241.6
(1.8)
P 		158
avr 246.4
(3) 		234.6
(2.4) 		144.7
(-2.5) 		136.1
(-3) 		156
(-1.9) 		229.4
(2.1) 		110
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191080_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9445
Sequence Type Exemplar sequence
Representative Public ID C02F4.1 NCBI
Target Description C02F4.1 /REP_DB=WormBase Gene ID /WP=CE24779 /GEN=ced-5 /TR=O17758 /GB=CAB61006.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=DOCK180 protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069537(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069537 NCBI Caenorhabditis elegans CEll Death abnormality family member (ced-5) (ced-5) mRNA, complete cds. 11/11 A 
SNAP00000033612 ENSEMBL cdna:SNAP chromosome:CEL140:IV:10489645:10492602:1 11/11 None
GENEFINDER00000033616 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:10489674:10492653:1 11/11 None
C02F4.1 ENSEMBL cdna:known chromosome:CEL140:IV:10484082:10492924:1 gene:C02F4.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:10484102-10492608(+) 99.81 100.0
Public Domain and Genome References
Gene Title DOCK180 protein
Gene Symbol ced-5
Ensembl C02F4.1
Entrez Gene 177942 Entrez gene
SwissProt O17758 EMBL-EBI
WormBase CE24779 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1587384_AT similar to Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180) cfa
CANINE_2:CFA.15172.1.A1_AT similar to Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180) cfa
CANINE_2:CFAAFFX.20305.1.S1_AT similar to Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180) cfa
CANINE_2:CFAAFFX.20305.1.S1_S_AT similar to Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180) cfa
DROSOPHILA_2:1631013_AT myoblast city dm
DROSGENOME1:143808_AT myoblast city dm
HG-U133_PLUS_2:203187_AT dedicator of cytokinesis 1 hs
HG-FOCUS:203187_AT dedicator of cytokinesis 1 hs
HG-U133A:203187_AT dedicator of cytokinesis 1 hs
HG-U133A_2:203187_AT dedicator of cytokinesis 1 hs
HUGENEFL:D50857_AT dedicator of cytokinesis 1 hs
U133_X3P:G4503354_3P_AT dedicator of cytokinesis 1 hs
U133_X3P:HS.309770.0.A1_3P_S_AT dedicator of cytokinesis 1 hs
U133_X3P:HS.309770.0.A1_3P_AT dedicator of cytokinesis 1 hs
HG-U133_PLUS_2:241708_AT dedicator of cytokinesis 1 hs
HG-U133B:241708_AT dedicator of cytokinesis 1 hs
HG-U133_PLUS_2:241709_S_AT dedicator of cytokinesis 1 hs
HG-U133B:241709_S_AT dedicator of cytokinesis 1 hs
HG-U95AV2:37638_AT dedicator of cytokinesis 1 hs
HG-U133_PLUS_2:232930_AT Dedicator of cytokinesis 1 hs
HG-U133B:232930_AT Dedicator of cytokinesis 1 hs
U133_X3P:HS2.306387.1.S1_3P_S_AT Dedicator of cytokinesis 1 hs
U133_X3P:HS.6618.0.S1_3P_AT Dedicator of cytokinesis 1 hs
U133_X3P:HS.150058.0.A1_3P_AT Dedicator of cytokinesis 1 hs
HG-U133_PLUS_2:1564407_A_AT Dedicator of cytokinesis 1 hs
HG-U133_PLUS_2:244435_AT Dedicator of cytokinesis 1 hs
HG-U133B:244435_AT Dedicator of cytokinesis 1 hs
HG-U95D:80639_AT Dedicator of cytokinesis 1 hs
HG-U133_PLUS_2:232973_AT Dedicator of cytokinesis 1 hs
HG-U133B:232973_AT Dedicator of cytokinesis 1 hs
HG-U133_PLUS_2:234170_AT Dedicator of cytokinesis 1 hs
HG-U133B:234170_AT Dedicator of cytokinesis 1 hs
HG-U133_PLUS_2:236877_AT Dedicator of cytokinesis 1 hs
HG-U133B:236877_AT Dedicator of cytokinesis 1 hs
HG-U133_PLUS_2:237311_AT Dedicator of cytokinesis 1 hs
HG-U133B:237311_AT Dedicator of cytokinesis 1 hs
HG-U95B:54523_AT Dedicator of cytokinesis 1 hs
HG-U95E:68890_AT Dedicator of cytokinesis 1 hs
HG-U95D:81984_AT Dedicator of cytokinesis 1 hs
HG-U95D:82128_AT Dedicator of cytokinesis 1 hs
HG-U95D:83765_AT Dedicator of cytokinesis 1 hs
HU35KSUBB:RC_T16498_AT Dedicator of cytokinesis 1 hs
U133_X3P:HS.161353.0.A1_3P_AT Dedicator of cytokinesis 1 hs
U133_X3P:HS.163206.0.A1_3P_AT Dedicator of cytokinesis 1 hs
MOUSE430_2:1457806_AT dedicator of cyto-kinesis 1 mm
MOE430B:1457806_AT dedicator of cyto-kinesis 1 mm
MG-U74BV2:109494_AT dedicator of cyto-kinesis 1 mm
MG-U74BV2:114940_AT dedicator of cyto-kinesis 1 mm
MG-U74BV2:163609_AT dedicator of cyto-kinesis 1 mm
MOE430A:1452220_AT dedicator of cyto-kinesis 1 mm
MOUSE430A_2:1452220_AT dedicator of cyto-kinesis 1 mm
MOUSE430_2:1452220_AT dedicator of cyto-kinesis 1 mm
MOE430B:1443991_AT dedicator of cyto-kinesis 1 mm
MOUSE430_2:1443991_AT dedicator of cyto-kinesis 1 mm
MOE430B:1443390_AT Dedicator of cyto-kinesis 1, mRNA (cDNA clone IMAGE:3493084) mm
MOUSE430_2:1443390_AT Dedicator of cyto-kinesis 1, mRNA (cDNA clone IMAGE:3493084) mm
MOE430B:1443760_AT Dedicator of cyto-kinesis 1, mRNA (cDNA clone IMAGE:3493084) mm
MOUSE430_2:1443760_AT Dedicator of cyto-kinesis 1, mRNA (cDNA clone IMAGE:3493084) mm
MU19KSUBC:TC37307_AT Dedicator of cyto-kinesis 1, mRNA (cDNA clone IMAGE:3493084) mm
RG-U34C:RC_AA818811_AT similar to Dock1 protein rn
RAE230A:1389102_AT similar to Dock1 protein rn
RAT230_2:1389102_AT similar to Dock1 protein rn
RAE230B:1391937_AT similar to Dock1 protein rn
RAT230_2:1391937_AT similar to Dock1 protein rn
RAE230B:1378943_AT Similar to Dock1 protein rn
RAT230_2:1378943_AT Similar to Dock1 protein rn
RAE230B:1396908_AT Similar to Dock1 protein rn
RAT230_2:1396908_AT Similar to Dock1 protein rn
RG-U34B:RC_AA924601_AT Similar to Dock1 protein rn
RG-U34B:RC_AA955917_AT Similar to Dock1 protein rn
Protein Similarities
Method ID Description E-Value
blast CAB61006 Hypothetical protein C02F4.1 [Caenorhabditis elegans] emb|CAB60991.1| Hypothetical protein C02F4.1 [Caenorhabditis elegans] ref|NP_501938.1| CEll Death abnormality family member (ced-5) [Caenorhabditis elegans] gb|AAC38973.1| CED-5 [Caenorhabditis elegans] 0.0
blast T18868 myoblast city protein homolog - Caenorhabditis elegans 0.0
blast CAE63798 Hypothetical protein CBG08340 [Caenorhabditis briggsae] 0.0
Sequence
Target Sequence 
>C. ELEGANS:191080_S_AT
gttatgttcatgctagtcgttgtcaaggagaagcaagagcaattaatacaatgttggcag
attcatttgacagtcatcgtagatatgttgaggaaaactttggaaaaacaagatccaggt
tgccaacacatgctaatattcgactatcatcgtttgattcggattcgatcaatgatggaa
tgatgacaatgaagtcaggaaaagctgcagtacttggaaacgctgtggctaacctaattt
attcgaacaaacgatctagtggacctggaactcctgtcaacttgtcaagtcgttcagccc
cttcattcgataacatttcatctaaacttcggagttctctggcaatttccaagcttgcac
ccccaccgcgacctccaaatcccatatctccaattaaccgtggaccatcttcaaattatg
aaggaatccgtatgagagctcattcacatcaggcttcaacagtctctcttaatcatatgt
cagttgctccaccacttccacctcgtccagatcgtcctgatatgg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTTATGTTCATGCTAGTCGTTGTCA 202 447 4802 Antisense
AGATCCAGGTTGCCAACACATGCTA 305 65 4912 Antisense
GGAAACGCTGTGGCTAACCTAATTT 46 529 5017 Antisense
TAGTGGACCTGGAACTCCTGTCAAC 26 655 5058 Antisense
AGCCCCTTCATTCGATAACATTTCA 538 83 5097 Antisense
GGAGTTCTCTGGCAATTTCCAAGCT 689 517 5132 Antisense
AAATCCCATATCTCCAATTAACCGT 249 117 5178 Antisense
GAGAGCTCATTCACATCAGGCTTCA 416 395 5235 Antisense
GGCTTCAACAGTCTCTCTTAATCAT 231 537 5253 Antisense
TAATCATATGTCAGTTGCTCCACCA 576 635 5271 Antisense
CCTCGTCCAGATCGTCCTGATATGG 578 267 5302 Antisense
Sequence Source Affymetrix Proprietary Database