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[191072_at] ADP/ATP carrier protein

Description F17E5.2 /REP_DB=WormBase Gene ID /WP=CE23667 /TR=SW:Q19529 /GB=CAA90761.2 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=ADP-ATP carrier protein
Cluster 6grp_high1_10_10 > 17      4grp_highest_8_8 > 47      4grp_high_8_8 > 11      6grp_total > 17      4grp_total > 21      6grp_high1_sub > De      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 88
1 2 3 4 range
A 112.4
(-0.1)
P 		69.8
(-3)
P 		98.1
(-1.1)
P 		157.4
(3)
P 		88
B 136.2
(3)
P 		106.8
(0.3)
P 		80.3
(-2.1)
P 		70.4
(-3)
P 		66
C 93.4
(-2.3)
P 		113.6
(-0.6)
P 		85.4
(-3)
P 		154.7
(3)
P 		69
avr 114
(1) 		96.7
(-1.7) 		87.9
(-3) 		127.5
(3) 		40

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 136
1 2 3 4 5 6 range
A 188.8
(3)
P 		92.5
(-1.3)
P 		52.9
(-3)
A 		87.1
(-1.5)
P 		85.4
(-1.6)
P 		94.7
(-1.2)
P 		136
B 96.7
(0.6)
P 		122.6
(3)
P 		94.4
(0.4)
P 		95.6
(0.5)
P 		58.3
(-3)
P 		67.5
(-2.1)
P 		64
C 150.4
(3)
P 		108.8
(-0.2)
P 		72.4
(-3)
P 		95.4
(-1.2)
P 		77
(-2.6)
P 		80
(-2.4)
P 		78
avr 145.3
(3) 		108
(-0.1) 		73.2
(-3) 		92.7
(-1.4) 		73.6
(-3) 		80.7
(-2.4) 		72
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 28
1 2 3 4 range
A 40.9
(3)
P 		15.2
(-3)
P 		25.6
(-0.6)
P 		23
(-1.2)
P 		26
B 43.4
(3)
P 		26.4
(-0.6)
P 		18.6
(-2.2)
P 		15
(-3)
P 		28
C 30.9
(1.4)
P 		32.7
(3)
P 		29.8
(0.4)
P 		26.1
(-3)
P 		7
avr 38.4
(3) 		24.8
(-1.8) 		24.7
(-1.8) 		21.4
(-3) 		17

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 44
1 2 3 4 5 6 range
A 34.8
(3)
P 		32.9
(2.5)
P 		11.5
(-3)
A 		22.1
(-0.3)
P 		25.8
(0.7)
P 		23
(-0)
P 		23
B 33.7
(0.6)
P 		40.8
(3)
P 		22.9
(-3)
P 		25.3
(-2.2)
P 		23.7
(-2.7)
P 		25.2
(-2.2)
P 		18
C 55.8
(3)
P 		33.2
(-0.6)
P 		18.4
(-3)
P 		19.2
(-2.9)
P 		24.9
(-2)
P 		26.8
(-1.7)
P 		37
avr 41.4
(3) 		35.6
(1.5) 		17.6
(-3) 		22.2
(-1.8) 		24.8
(-1.2) 		25
(-1.1) 		24
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191072_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16675
Sequence Type Exemplar sequence
Representative Public ID F17E5.2 NCBI
Target Description F17E5.2 /REP_DB=WormBase Gene ID /WP=CE23667 /TR=SW:Q19529 /GB=CAA90761.2 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=ADP-ATP carrier protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077680(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077680 NCBI Caenorhabditis elegans F17E5.2 (F17E5.2) mRNA, complete cds. 10/11 None
SNAP00000016292 ENSEMBL cdna:SNAP chromosome:CEL140:X:12394337:12398139:1 10/11 None
GENEFINDER00000016298 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:12394337:12398952:1 10/11 None
F17E5.2 ENSEMBL cdna:known chromosome:CEL140:X:12394186:12399411:1 gene:F17E5.2 10/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:12394336-12398407(+) 100.0 100.0
Public Domain and Genome References
Gene Title ADP/ATP carrier protein
Ensembl F17E5.2
Entrez Gene 181399 Entrez gene
SwissProt Q19529 EMBL-EBI
WormBase CE37355 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:250623_AT mitochondrial substrate carrier family protein at
CANINE_2:CFAAFFX.30755.1.S1_S_AT similar to solute carrier family 25, member 25 isoform a cfa
DROSOPHILA_2:1629806_A_AT dm
DROSGENOME1:152957_AT dm
DROSGENOME1:148658_AT dm
CHICKEN:GGAAFFX.26398.2.S1_S_AT similar to mitochondrial Ca2+-dependent solute carrier; solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 gga
MG-U74AV2:98569_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 mm
MG-U74BV2:162537_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 mm
MOE430A:1424735_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 mm
MOUSE430A_2:1424735_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 mm
MOUSE430_2:1424735_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 mm
MOE430B:1454284_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 mm
MOUSE430_2:1454284_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 mm
MOE430B:1447856_X_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 mm
MOUSE430_2:1447856_X_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 mm
MU19KSUBC:TC36285_AT Solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25, mRNA (cDNA clone MGC:47196 IMAGE:5368306) mm
MU19KSUBC:TC37114_AT Solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25, mRNA (cDNA clone MGC:47196 IMAGE:5368306) mm
RG-U34C:RC_AA817759_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 rn
RAE230A:1371754_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 rn
RAT230_2:1371754_AT solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 rn
YEAST_2:1769358_AT Probable transporter, member of the Ca2+-binding subfamily of the mitochondrial carrier family, with two EF-hand motifs; Pet9p and Sal1p have an overlapping function critical for viability; polymorphic in different S. cerevisiae strains Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6810 transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5743 mitochondrial inner membrane inferred from electronic annotation QuickGO AmiGO
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5488 binding inferred from electronic annotation QuickGO AmiGO
5509 calcium ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA90761 Hypothetical protein F17E5.2 [Caenorhabditis elegans] ref|NP_510081.3| F17E5.2 [Caenorhabditis elegans] sp|Q19529|CMC3_CAEEL Probable calcium-binding mitochondrial carrier F17E5.2 0.0
blast T21074 hypothetical protein F17E5.2 - Caenorhabditis elegans 0.0
blast CAE57255 Hypothetical protein CBG00135 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 3.3E-35
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 2.3E-34
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 4.1E-27
Pfam IPR002048 EMBL-EBI Calcium-binding EF-hand 1.2E-4
Pfam IPR002048 EMBL-EBI Calcium-binding EF-hand 3.3E-5
Pfam IPR002048 EMBL-EBI Calcium-binding EF-hand 0.088
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.5E-19
Sequence
Target Sequence 
>C. ELEGANS:191072_AT
ttcttcagcgggtgccatttcacaaactgccatctatcctatggaggtgatgaaaactag
gttagctcttcgacgaacgggtcaactcgataaggggatgtttcactttgctcacaaaat
gtatacaaaagaaggcattaaatgtttttacaaggggtatctaccaaatctgttgggcat
tattccatatgcgggtatagatttgacggtctatgaatcgttaaaatcaatgtacaccaa
gtactacactgaacacacggagcctggagttcttgcgctactcgcatgcggaacatgcag
ttctacatgtgggcaactagcaagctatccgctagctttagttcgaacaaggcttcaagc
tagagcaatttctccgaaaaactcaacacagccggatacaatggttgggcaattcaagca
cattttgcagactgagggattcactggattatacagaggaatcacaccgaatttcatgaa
gtggtttagtaaatgtagttctgctcactttaatatgcgact

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTCTTCAGCGGGTGCCATTTCACAA 481 687 1155 Antisense
ATTTCACAAACTGCCATCTATCCTA 49 17 1171 Antisense
CTAGGTTAGCTCTTCGACGAACGGG 274 1 1211 Antisense
GAACGGGTCAACTCGATAAGGGGAT 386 1 1229 Antisense
TAAGGGGATGTTTCACTTTGCTCAC 302 637 1245 Antisense
GTACTACACTGAACACACGGAGCCT 445 457 1395 Antisense
TTCTTGCGCTACTCGCATGCGGAAC 507 689 1424 Antisense
GTGGGCAACTAGCAAGCTATCCGCT 370 485 1463 Antisense
GCTATCCGCTAGCTTTAGTTCGAAC 38 303 1478 Antisense
CAGAGGAATCACACCGAATTTCATG 2 205 1608 Antisense
GTTCTGCTCACTTTAATATGCGACT 318 443 1652 Antisense
Sequence Source Affymetrix Proprietary Database