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[191070_at] cyclophilin

Description F59E10.2 /REP_DB=WormBase Gene ID /WP=CE01596 /GEN=cyp-4 /TR=SW:P52012 /GB=CAA87053.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=cyclophilin
Cluster 6grp_highest_10_10 > 57      6grp_high1_10_10 > 75      4grp_highest_8_8 > 43      4grp_high_8_8 > 24      6grp_highest_nonorm > 73      6grp_total > 75      4grp_total > 47      6grp_cgc > 57      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 230
1 2 3 4 range
A 534.7
(1.1)
P
539
(3)
P
525.4
(-3)
P
529.8
(-1.1)
P
14
B 586.2
(3)
P
441.1
(-3)
P
517.1
(0.1)
P
494.1
(-0.8)
P
145
C 643.6
(3)
P
413.9
(-3)
P
486.6
(-1.1)
P
486.6
(-1.1)
P
230
avr 588.2
(3)
464.7
(-3)
509.7
(-0.8)
503.5
(-1.1)
124

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 370
1 2 3 4 5 6 range
A 509.6
(-1.8)
P
481.8
(-3)
P
521.2
(-1.3)
P
556.9
(0.2)
P
565.8
(0.6)
P
621.7
(3)
P
140
B 540.6
(-0)
P
410.2
(-3)
P
605.2
(1.5)
P
577.9
(0.8)
P
517.4
(-0.6)
P
673
(3)
P
263
C 421.7
(-3)
P
515.3
(-1.4)
P
589
(-0.2)
P
589.1
(-0.2)
P
470.5
(-2.2)
P
780.4
(3)
P
359
avr 490.6
(-2.4)
469.1
(-3)
571.8
(-0.2)
574.6
(-0.2)
517.9
(-1.7)
691.7
(3)
223
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 135
1 2 3 4 range
A 194.7
(3)
P
117
(-1)
P
137.3
(0.1)
P
77.6
(-3)
P
117
B 186.9
(3)
P
108.9
(-2.7)
P
119.8
(-1.9)
P
105.3
(-3)
P
82
C 213
(3)
P
119
(-1.3)
P
169.6
(1)
P
82
(-3)
P
131
avr 198.2
(3)
115
(-1.5)
142.2
(-0.1)
88.3
(-3)
110

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 167
1 2 3 4 5 6 range
A 93.9
(-3)
P
171.4
(3)
P
113.5
(-1.5)
P
141.2
(0.7)
P
170.7
(2.9)
P
151.4
(1.5)
P
78
B 188.1
(-0.3)
P
136.5
(-3)
P
147
(-2.4)
P
153.1
(-2.1)
P
210.2
(0.9)
P
250.9
(3)
P
114
C 156.3
(-1.4)
P
157.2
(-1.4)
P
149.9
(-1.7)
P
118.5
(-3)
P
152.3
(-1.6)
P
261.2
(3)
P
143
avr 146.1
(-2.3)
155
(-1.7)
136.8
(-3)
137.6
(-2.9)
177.7
(-0.1)
221.2
(3)
84
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191070_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2703
Sequence Type Exemplar sequence
Representative Public ID F59E10.2 NCBI
Target Description F59E10.2 /REP_DB=WormBase Gene ID /WP=CE01596 /GEN=cyp-4 /TR=SW:P52012 /GB=CAA87053.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=cyclophilin
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063936(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_063936 NCBI Caenorhabditis elegans F59E10.2 (cyclophilin) mRNA, complete cds. 11/11 None
F59E10.2 ENSEMBL cdna:known chromosome:CEL140:II:10870740:10872522:-1 gene:F59E10.2 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000001005 3/11 Cross Hyb Matching Probes None
GENEFINDER00000001010 3/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:10870736-10872514(-) 100.0 100.0
Public Domain and Genome References
Gene Title cyclophilin
Gene Symbol cyn-4
Ensembl F59E10.2
Entrez Gene 174674 Entrez gene
SwissProt P52012 EMBL-EBI
WormBase CE01596 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:246980_AT peptidyl-prolyl cis-trans isomerase cyclophilin-type family protein at
CANINE:1586779_AT similar to peptidylprolyl isomerase-like 2 isoform a cfa
CANINE_2:CFA.6370.1.A1_AT similar to peptidylprolyl isomerase-like 2 isoform a cfa
CANINE_2:CFAAFFX.23620.1.S1_S_AT similar to peptidylprolyl isomerase-like 2 isoform a cfa
DROSOPHILA_2:1631622_AT dm
DROSGENOME1:153974_AT dm
CHICKEN:GGA.17248.2.S1_S_AT peptidylprolyl isomerase (cyclophilin)-like 2 gga
CHICKEN:GGAAFFX.1013.1.S1_AT peptidylprolyl isomerase (cyclophilin)-like 2 gga
CHICKEN:GGA.17248.2.A1_AT Similar to peptidylprolyl isomerase-like 2 isoform a; cyclophilin-like protein CyP-60; peptidylprolyl cis-trans isomerase; cyclophilin, 60kDa gga
HG-U133_PLUS_2:217407_X_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U133A_2:217407_X_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U133A:217407_X_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U133_PLUS_2:214986_X_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U133A_2:214986_X_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U133A:214986_X_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U95AV2:39111_S_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U133_PLUS_2:209299_X_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U133A:209299_X_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U133A_2:209299_X_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U133_PLUS_2:206064_S_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U133A:206064_S_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-FOCUS:206064_S_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U133A_2:206064_S_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HUGENEFL:U37219_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HUGENEFL:U37221_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
U133_X3P:G7657472_3P_A_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
U133_X3P:G13366578_3P_A_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
U133_X3P:HS.93523.4.A1_3P_X_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
U133_X3P:HS.93523.4.A1_3P_A_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
U133_X3P:HS.93523.3.A1_3P_A_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
U133_X3P:HS.93523.0.A2_3P_X_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
U133_X3P:HS.93523.0.A2_3P_A_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
U133_X3P:217407_3P_X_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
U133_X3P:214986_3P_X_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
U133_X3P:206063_3P_X_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U133A_2:206063_X_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U133_PLUS_2:206063_X_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U133A:206063_X_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U95AV2:33188_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U95AV2:35448_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U95D:92106_AT peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U133_PLUS_2:223999_AT Peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U133B:223999_AT Peptidylprolyl isomerase (cyclophilin)-like 2 hs
U133_X3P:G12751383_3P_AT Peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U95D:77409_AT Peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U133_PLUS_2:243414_AT Peptidylprolyl isomerase (cyclophilin)-like 2 hs
HG-U133B:243414_AT Peptidylprolyl isomerase (cyclophilin)-like 2 hs
U133_X3P:HS.174159.0.A1_3P_AT Peptidylprolyl isomerase (cyclophilin)-like 2 hs
MOE430A:1452920_A_AT peptidylprolyl isomerase (cyclophilin)-like 2 mm
MOUSE430A_2:1452920_A_AT peptidylprolyl isomerase (cyclophilin)-like 2 mm
MOUSE430_2:1452920_A_AT peptidylprolyl isomerase (cyclophilin)-like 2 mm
MU11KSUBA:AA589416_RC_S_AT peptidylprolyl isomerase (cyclophilin)-like 2 mm
MG-U74AV2:95110_AT peptidylprolyl isomerase (cyclophilin)-like 2 mm
MG-U74AV2:95112_F_AT peptidylprolyl isomerase (cyclophilin)-like 2 mm
MG-U74AV2:95111_I_AT peptidylprolyl isomerase (cyclophilin)-like 2 mm
MG-U74BV2:164362_AT peptidylprolyl isomerase (cyclophilin)-like 2 mm
MG-U74CV2:167900_I_AT peptidylprolyl isomerase (cyclophilin)-like 2 mm
MG-U74CV2:170929_AT peptidylprolyl isomerase (cyclophilin)-like 2 mm
MOE430B:1442660_AT Peptidylprolyl isomerase (cyclophilin)-like 2, mRNA (cDNA clone MGC:19011 IMAGE:4021590) mm
MOUSE430_2:1442660_AT Peptidylprolyl isomerase (cyclophilin)-like 2, mRNA (cDNA clone MGC:19011 IMAGE:4021590) mm
MU19KSUBA:TC18603_AT Peptidylprolyl isomerase (cyclophilin)-like 2, mRNA (cDNA clone MGC:19011 IMAGE:4021590) mm
MU19KSUBA:TC21893_AT Peptidylprolyl isomerase (cyclophilin)-like 2, mRNA (cDNA clone MGC:19011 IMAGE:4021590) mm
MU19KSUBB:TC26252_AT Peptidylprolyl isomerase (cyclophilin)-like 2, mRNA (cDNA clone MGC:19011 IMAGE:4021590) mm
MU19KSUBB:TC32201_AT Peptidylprolyl isomerase (cyclophilin)-like 2, mRNA (cDNA clone MGC:19011 IMAGE:4021590) mm
RT-U34:RC_AA818726_AT peptidylprolyl isomerase (cyclophilin)-like 2 (predicted) rn
RG-U34A:RC_AA818726_AT peptidylprolyl isomerase (cyclophilin)-like 2 (predicted) rn
RAE230A:1375440_AT peptidylprolyl isomerase (cyclophilin)-like 2 (predicted) rn
RAT230_2:1375440_AT peptidylprolyl isomerase (cyclophilin)-like 2 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6457 protein folding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA87053 Hypothetical protein F59E10.2 [Caenorhabditis elegans] emb|CAA85417.1| Hypothetical protein F59E10.2 [Caenorhabditis elegans] gb|AAL27008.1| cyclophilin MOG-6 [Caenorhabditis elegans] ref|NP_496337.1| F59E10.2 [Caenorhabditis elegans] sp|P52012|CYP4_CAEEL Peptidyl-prolyl cis-trans isomerase 4 (PPIase) (Rotamase) (Cyclophilin-4) (Cyclophilin mog-6) (Masculinisation of germline protein 6) gb|AAC06337.1| cyclophilin isoform 4 [Caenorhabditis elegans] 0.0
blast CAE59592 Hypothetical protein CBG02999 [Caenorhabditis briggsae] 0.0
blast CAA06162 CB-CYP-4 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002130 EMBL-EBI Peptidyl-prolyl cis-trans isomerase, cyclophilin type 4.0E-48
Sequence
Target Sequence
>C. ELEGANS:191070_AT
tatgctgcaaggaggcgacccaactggtacaggacatggtggagaatcaatttgggataa
gccattctcagatgaattcatctccggtttctcccatgatgctcgaggtgtgctctcgat
ggctaataagggctctaacaccaacggatcacaattcttcattacattccggccgtgcaa
gtatttggacagaaagcacacaatttttgggagacttgttggaggacaggatacactaac
gacgattgaaaagttggaaactgaagagggaactgatgttccgatggtttcagttgttat
tatgagagctgaagtatttgtggatccatttgaagaagctgagaaagaagttcaagctga
gagagcagagattttgaagaaaacttctaaggacgcagcttcattagcaaataaaaaagc
taaagaaactgcaacaaaaccagaagcagttggaactggagtcggcaagtacatgaagtc
ggccgcagctgtgaataaacgacaaggaaaaatggaagatgtacccttggaggccgcaaa
gaa


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
TATGCTGCAAGGAGGCGACCCAACT 65 657 996 Antisense
GGCGACCCAACTGGTACAGGACATG 132 539 1009 Antisense
AGATGAATTCATCTCCGGTTTCTCC 239 67 1065 Antisense
CTCCCATGATGCTCGAGGTGTGCTC 552 227 1086 Antisense
AGGTGTGCTCTCGATGGCTAATAAG 604 57 1101 Antisense
TAAGGGCTCTAACACCAACGGATCA 391 627 1122 Antisense
CACAATTCTTCATTACATTCCGGCC 200 195 1145 Antisense
ACATTCCGGCCGTGCAAGTATTTGG 140 103 1159 Antisense
ATGTTCCGATGGTTTCAGTTGTTAT 349 47 1271 Antisense
ATGAAGTCGGCCGCAGCTGTGAATA 163 43 1468 Antisense
ATGTACCCTTGGAGGCCGCAAAGAA 645 1 1514 Antisense
Sequence Source Affymetrix Proprietary Database