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[191046_s_at] Protein phosphatase 2A

Description F48E8.5 /REP_DB=WormBase Gene ID /WP=CE01957 /TR=SW:Q09543 /GB=AAC46541.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=Protein phosphatase 2A
Cluster 6grp_highest_10_10 > 30      6grp_high1_10_10 > 05      4grp_highest_8_8 > 25      4grp_high_8_8 > 60      6grp_highest_nonorm > 0      6grp_total > 05      4grp_total > 60      6grp_highest_sub > De      6grp_cgc > 21      6grp_high1_sub > De      6grp_cgc_sub > De      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1054
1 2 3 4 range
A 1879.5
(3)
P 		1366.3
(-0.6)
P 		1787.4
(2.4)
P 		1026.3
(-3)
P 		853
B 1395.9
(-2.6)
P 		2080.4
(3)
P 		1684.2
(-0.3)
P 		1351.8
(-3)
P 		729
C 1946.1
(2.2)
P 		1952.9
(2.3)
P 		2076
(3)
P 		1083.7
(-3)
P 		992
avr 1740.5
(2.1) 		1799.9
(2.6) 		1849.2
(3) 		1153.9
(-3) 		695

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 957
1 2 3 4 5 6 range
A 1418.6
(-1.9)
P 		1918.9
(3)
P 		1541.4
(-0.7)
P 		1312
(-3)
P 		1540.3
(-0.7)
P 		1385.4
(-2.3)
P 		607
B 2162
(3)
P 		1623.4
(-1.2)
P 		1643.9
(-1)
P 		1696.1
(-0.6)
P 		1522.5
(-1.9)
P 		1384.2
(-3)
P 		778
C 2269.2
(3)
P 		1487.3
(-2.1)
P 		1770.8
(-0.2)
P 		1569.1
(-1.5)
P 		1799
(-0.1)
P 		1345.6
(-3)
P 		924
avr 1949.9
(3) 		1676.5
(0.2) 		1652
(-0.1) 		1525.7
(-1.4) 		1620.6
(-0.4) 		1371.7
(-3) 		578
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 573
1 2 3 4 range
A 684.3
(3)
P 		296.6
(-1.4)
P 		467.3
(0.6)
P 		150.2
(-3)
P 		534
B 445.2
(1.2)
P 		513.8
(3)
P 		390.3
(-0.3)
P 		288.1
(-3)
P 		226
C 644.2
(2.1)
P 		561.5
(1.2)
P 		723.6
(3)
P 		182.7
(-3)
P 		541
avr 591.2
(3) 		457.3
(0.9) 		527.1
(2) 		207
(-3) 		384

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 580
1 2 3 4 5 6 range
A 261.5
(-3)
P 		682.4
(3)
P 		335.7
(-1.9)
P 		332.8
(-2)
P 		464.8
(-0.1)
P 		337.3
(-1.9)
P 		421
B 752.3
(3)
P 		540.4
(-0.6)
P 		399.2
(-3)
P 		449.2
(-2.2)
P 		618.6
(0.7)
P 		516.2
(-1)
P 		353
C 841.1
(3)
P 		453.8
(-1.4)
P 		450.7
(-1.5)
P 		315.5
(-3)
P 		582.1
(0)
P 		450.4
(-1.5)
P 		526
avr 618.3
(3) 		558.9
(1.6) 		395.2
(-2.3) 		365.8
(-3) 		555.2
(1.5) 		434.6
(-1.4) 		253
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191046_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7381
Sequence Type Exemplar sequence
Representative Public ID F48E8.5 NCBI
Target Description F48E8.5 /REP_DB=WormBase Gene ID /WP=CE01957 /TR=SW:Q09543 /GB=AAC46541.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=Protein phosphatase 2A
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065761(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065761 NCBI Caenorhabditis elegans Phosphatase 2A regulatory A subunit family member (paa-1) (paa-1) mRNA, complete cds. 11/11 None
GENEFINDER00000003650 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:5450450:5452917:1 11/11 None
SNAP00000003640 ENSEMBL cdna:SNAP chromosome:CEL140:III:5450696:5452717:1 11/11 None
F48E8.5.2 ENSEMBL cdna:known chromosome:CEL140:III:5450061:5453567:1 gene:F48E8.5 11/11 None
F48E8.5.3 ENSEMBL cdna:known chromosome:CEL140:III:5450683:5453087:1 gene:F48E8.5 11/11 None
F48E8.5.1 ENSEMBL cdna:known chromosome:CEL140:III:5450685:5453092:1 gene:F48E8.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:5450053-5452716(+) 100.0 100.0
Public Domain and Genome References
Gene Title Protein phosphatase 2A
Gene Symbol paa-1
Ensembl F48E8.5
Entrez Gene 175750 Entrez gene
SwissProt Q09543 EMBL-EBI
WormBase CE30997 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:255731_AT serine/threonine protein phosphatase 2A (PP2A) regulatory subunit A (RCN1) at
ATGENOME1:16098_S_AT serine/threonine protein phosphatase 2A (PP2A) regulatory subunit A (RCN1) at
CANINE:1595737_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform cfa
CANINE:1589111_S_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform cfa
CANINE_2:CFA.11423.1.A1_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform cfa
CANINE_2:CFA.9021.1.A1_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform cfa
CANINE_2:CFAAFFX.5077.1.S1_S_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform cfa
HG-U133_PLUS_2:200695_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform hs
HG-U133A:200695_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform hs
HG-FOCUS:200695_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform hs
HG-U133A_2:200695_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform hs
HG-U95AV2:922_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform hs
HC-G110:922_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform hs
HU35KSUBD:RC_T26513_F_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform hs
HU35KSUBD:RC_T26513_I_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform hs
HUGENEFL:J02902_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform hs
U133_X3P:G7657474_3P_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform hs
HG-U95AV2:40867_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform hs
HG-U95D:91243_AT Protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform hs
MOE430A:1438174_X_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MOUSE430A_2:1438174_X_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MOUSE430_2:1438174_X_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MOUSE430A_2:1415819_A_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MOUSE430_2:1415819_A_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MOE430A:1415819_A_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MU11KSUBB:MSA.6384.0_S_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MU11KSUBB:MSA.5980.0_F_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MU11KSUBB:MSA.13801.0_F_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MU11KSUBB:MSA.33643.0_F_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MU11KSUBB:Z31244_S_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MU11KSUBB:MSA.28243.0_F_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MG-U74AV2:92573_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MOE430A:1438991_X_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MOUSE430A_2:1438991_X_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MOUSE430_2:1438991_X_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MOE430A:1455929_X_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MOUSE430A_2:1455929_X_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MOUSE430_2:1455929_X_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MOE430A:1438383_X_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MOUSE430A_2:1438383_X_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MOUSE430_2:1438383_X_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform mm
MU19KSUBC:TC37982_F_AT Protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform, mRNA (cDNA clone MGC:7086 IMAGE:3157293) mm
MU19KSUBC:TC37982_I_AT Protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform, mRNA (cDNA clone MGC:7086 IMAGE:3157293) mm
MU19KSUBC:TC40196_AT Protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform, mRNA (cDNA clone MGC:7086 IMAGE:3157293) mm
RG-U34A:RC_AA800669_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform rn
RG-U34A:D14418_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform rn
RAE230A:1375245_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform rn
RAT230_2:1375245_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform rn
RAE230B:1381024_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform rn
RAT230_2:1381024_AT protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform rn
YEAST_2:1779247_AT Regulatory subunit A of the heterotrimeric protein phosphatase 2A, which also contains regulatory subunit Cdc55p and either catalytic subunit Pph21p or Pph22p; required for cell morphogenesis and for transcription by RNA polymerase III Sc
Protein Similarities
Method ID Description E-Value
blast AAC46541 Phosphatase 2a regulatory a subunit protein 1 [Caenorhabditis elegans] ref|NP_498162.2| Phosphatase 2A regulatory A subunit family member (paa-1) [Caenorhabditis elegans] sp|Q09543|2AAA_CAEEL Probable protein phosphatase PP2A regulatory subunit (Protein phosphatase PP2A regulatory subunit A) 0.0
blast CAE61350 Hypothetical protein CBG05190 [Caenorhabditis briggsae] 0.0
blast AAH78080 Ppp2r1a-B-prov protein [Xenopus laevis] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000357 EMBL-EBI HEAT 7.7E-7
Pfam IPR000357 EMBL-EBI HEAT 3.0E-10
Pfam IPR000357 EMBL-EBI HEAT 2.4E-8
Pfam IPR000357 EMBL-EBI HEAT 8.3E-9
Pfam IPR000357 EMBL-EBI HEAT 2.4E-5
Pfam IPR000357 EMBL-EBI HEAT 4.2E-12
Pfam IPR000357 EMBL-EBI HEAT 5.0E-8
Pfam IPR000357 EMBL-EBI HEAT 2.6E-8
Pfam IPR000357 EMBL-EBI HEAT 2.1E-6
Pfam IPR000357 EMBL-EBI HEAT 1.4E-12
Pfam IPR000357 EMBL-EBI HEAT 7.7E-7
Pfam IPR000357 EMBL-EBI HEAT 3.0E-10
Pfam IPR000357 EMBL-EBI HEAT 2.4E-8
Pfam IPR000357 EMBL-EBI HEAT 8.3E-9
Pfam IPR000357 EMBL-EBI HEAT 2.4E-5
Pfam IPR000357 EMBL-EBI HEAT 4.2E-12
Pfam IPR000357 EMBL-EBI HEAT 5.0E-8
Pfam IPR000357 EMBL-EBI HEAT 2.6E-8
Pfam IPR000357 EMBL-EBI HEAT 2.1E-6
Pfam IPR000357 EMBL-EBI HEAT 1.4E-12
Sequence
Target Sequence 
>C. ELEGANS:191046_S_AT
gttcgcctcaatattatttccagtcttgataaggtcaatgaagtgatcggagcagctcaa
ttgtccacatccctcttgccagccatcgttggattggccgaggatggaaaatggagagtt
cgactcgcaattgttcaattcatgccacttcttgcttcccagttgggacaagaattcttc
gatgagaagttgcttccgctttgtttgaactggcttaccgaccatgtgttctcaatccgc
gaggcatcgaccctcatcatgaaggaactgacacagaagtttggaggacaatgggctagc
acgaatattgtaccaaaaatgcagaaacttcagaaggacaccaactacctgcagagaatg
acatgcttgttctgtttgaatacactcagtgaggcgatgactcaggagcagattctgaag
gagattatgccaattgtgaaagatcttgtcgaggatgacgtgccgaatgtcagattcaac
gccgcaaagagtttgaagcgaattggaaagaacttgaccccaagtacattgacgtccgag
gtgaagccactgctcgagaagctcggaaaagattcagactttgacgttcgatacttttc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTTCGCCTCAATATTATTTCCAGTC 452 441 1378 Antisense
CCAGCCATCGTTGGATTGGCCGAGG 107 273 1456 Antisense
GAGAGTTCGACTCGCAATTGTTCAA 400 395 1491 Antisense
GCAATTGTTCAATTCATGCCACTTC 519 323 1504 Antisense
TTGCTTCCGCTTTGTTTGAACTGGC 278 699 1567 Antisense
GCATCGACCCTCATCATGAAGGAAC 612 309 1621 Antisense
GACACCAACTACCTGCAGAGAATGA 477 367 1714 Antisense
GCCGAATGTCAGATTCAACGCCGCA 283 285 1839 Antisense
ATTGACGTCCGAGGTGAAGCCACTG 136 3 1905 Antisense
AAGCCACTGCTCGAGAAGCTCGGAA 688 147 1921 Antisense
CAGACTTTGACGTTCGATACTTTTC 691 193 1952 Antisense
Sequence Source Affymetrix Proprietary Database