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[191041_s_at] acyl-CoA dehydrogenase

Description T08G2.3 /REP_DB=WormBase Gene ID /WP=CE07473 /TR=SW:Q22347 /GB=AAB52493.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=acyl-CoA dehydrogenase
Cluster 6grp_highest_10_10 > 73      6grp_high1_10_10 > 37      4grp_highest_8_8 > 26      4grp_high_8_8 > 59      6grp_highest_nonorm > 47      6grp_total > 48      4grp_total > 60      6grp_highest_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1485
1 2 3 4 range
A 3239.8
(-0.2)
P 		3806.1
(3)
P 		3518.2
(1.4)
P 		2728.5
(-3)
P 		1078
B 3620.7
(0.7)
P 		3050.9
(-1.9)
P 		4136.6
(3)
P 		2798.5
(-3)
P 		1338
C 3265
(1.4)
P 		3115.7
(0.3)
P 		3491.1
(3)
P 		2651.2
(-3)
P 		840
avr 3375.2
(0.9) 		3324.2
(0.6) 		3715.3
(3) 		2726.1
(-3) 		989

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2511
1 2 3 4 5 6 range
A 4233.7
(2.7)
P 		2140.8
(-2.3)
P 		2882.3
(-0.5)
P 		2889.3
(-0.5)
P 		1834.7
(-3)
P 		4345.9
(3)
P 		2511
B 4007.5
(3)
P 		2097.8
(-2.7)
P 		3357.4
(1.1)
P 		2830.5
(-0.5)
P 		1999.7
(-3)
P 		3146.1
(0.4)
P 		2008
C 4243
(3)
P 		2169.5
(-3)
P 		3024.6
(-0.5)
P 		2389.7
(-2.4)
P 		2287.5
(-2.7)
P 		3285.8
(0.2)
P 		2074
avr 4161.4
(3) 		2136
(-2.7) 		3088.1
(-0) 		2703.2
(-1.1) 		2040.6
(-3) 		3592.6
(1.4) 		2121
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 817
1 2 3 4 range
A 1179.6
(3)
P 		826.2
(0.3)
P 		919.7
(1)
P 		399.4
(-3)
P 		780
B 1154.6
(3)
P 		753.5
(-1.3)
P 		958.5
(0.9)
P 		596.4
(-3)
P 		558
C 1080.8
(1.9)
P 		895.8
(0.5)
P 		1216.7
(3)
P 		447
(-3)
P 		770
avr 1138.3
(3) 		825.2
(0.1) 		1031.6
(2) 		480.9
(-3) 		657

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1092
1 2 3 4 5 6 range
A 780.5
(-0.3)
P 		761.4
(-0.5)
P 		627.7
(-2.1)
P 		732.8
(-0.9)
P 		553.6
(-3)
P 		1058.1
(3)
P 		505
B 1394.4
(3)
P 		698.3
(-3)
P 		815.3
(-2)
P 		749.7
(-2.6)
P 		812.4
(-2)
P 		1173.2
(1.1)
P 		696
C 1572.7
(3)
P 		662
(-2)
P 		769.8
(-1.4)
P 		480.6
(-3)
P 		740.2
(-1.6)
P 		1100
(0.4)
P 		1092
avr 1249.2
(3) 		707.2
(-2.5) 		737.6
(-2.2) 		654.4
(-3) 		702.1
(-2.5) 		1110.4
(1.6) 		595
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191041_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17924
Sequence Type Exemplar sequence
Representative Public ID T08G2.3 NCBI
Target Description T08G2.3 /REP_DB=WormBase Gene ID /WP=CE07473 /TR=SW:Q22347 /GB=AAB52493.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=acyl-CoA dehydrogenase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_078387(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_078387 NCBI Caenorhabditis elegans T08G2.3 (T08G2.3) mRNA, complete cds. 11/11 A 
SNAP00000027867 ENSEMBL cdna:SNAP chromosome:CEL140:X:17213179:17214808:-1 11/11 None
GENEFINDER00000027887 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:17213179:17214808:-1 11/11 None
T08G2.3.1 ENSEMBL cdna:known chromosome:CEL140:X:17213070:17214817:-1 gene:T08G2.3 11/11 A 
T08G2.3.2 ENSEMBL cdna:known chromosome:CEL140:X:17213070:17214815:-1 gene:T08G2.3 11/11 A 
T08G2.3.3 ENSEMBL cdna:known chromosome:CEL140:X:17213089:17214838:-1 gene:T08G2.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:17213178-17214808(-) 100.0 100.0
Public Domain and Genome References
Gene Title acyl-CoA dehydrogenase
Ensembl T08G2.3
Entrez Gene 181757 Entrez gene
SwissProt Q22347 EMBL-EBI
WormBase CE07473 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1604449_AT similar to Acyl-CoA dehydrogenase, medium-chain specific, mitochondrial precursor (MCAD) cfa
CANINE_2:CFA.1658.1.S1_A_AT similar to Acyl-CoA dehydrogenase, medium-chain specific, mitochondrial precursor (MCAD) cfa
CANINE_2:CFAAFFX.31225.1.S1_AT similar to Acyl-CoA dehydrogenase, medium-chain specific, mitochondrial precursor (MCAD) cfa
CANINE_2:CFAAFFX.31225.1.S1_S_AT similar to Acyl-CoA dehydrogenase, medium-chain specific, mitochondrial precursor (MCAD) cfa
DROSOPHILA_2:1626566_AT dm
DROSGENOME1:154110_AT dm
HG-U133A:202502_AT acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain hs
HG-U133A_2:202502_AT acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain hs
HG-U133_PLUS_2:202502_AT acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain hs
HG-FOCUS:202502_AT acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain hs
HUGENEFL:M91432_AT acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain hs
U133_X3P:G4557230_3P_AT acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain hs
HG-U95AV2:37532_AT acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain hs
MOE430A:1415984_AT acetyl-Coenzyme A dehydrogenase, medium chain mm
MOUSE430A_2:1415984_AT acetyl-Coenzyme A dehydrogenase, medium chain mm
MOUSE430_2:1415984_AT acetyl-Coenzyme A dehydrogenase, medium chain mm
MU11KSUBA:U07159_F_AT acetyl-Coenzyme A dehydrogenase, medium chain mm
MU11KSUBB:MSA.1660.0_F_AT acetyl-Coenzyme A dehydrogenase, medium chain mm
MG-U74AV2:92581_AT acetyl-Coenzyme A dehydrogenase, medium chain mm
MU19KSUBA:TC16398_AT Acetyl-Coenzyme A dehydrogenase, medium chain, mRNA (cDNA clone MGC:19161 IMAGE:4222450) mm
MU19KSUBA:TC16399_F_AT Acetyl-Coenzyme A dehydrogenase, medium chain, mRNA (cDNA clone MGC:19161 IMAGE:4222450) mm
MU19KSUBA:TC21660_AT Acetyl-Coenzyme A dehydrogenase, medium chain, mRNA (cDNA clone MGC:19161 IMAGE:4222450) mm
RT-U34:J02791_AT acetyl-Coenzyme A dehydrogenase, medium chain rn
RG-U34A:J02791_AT acetyl-Coenzyme A dehydrogenase, medium chain rn
RAE230A:1367702_AT acetyl-Coenzyme A dehydrogenase, medium chain rn
RAT230_2:1367702_AT acetyl-Coenzyme A dehydrogenase, medium chain rn
RG-U34C:RC_AI112174_AT Acetyl-Coenzyme A dehydrogenase, medium chain rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3995 acyl-CoA dehydrogenase activity inferred from electronic annotation QuickGO AmiGO
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB52493 Hypothetical protein T08G2.3 [Caenorhabditis elegans] ref|NP_510788.1| T08G2.3 [Caenorhabditis elegans] sp|Q22347|ACADM_CAEEL Probable acyl-CoA dehydrogenase, medium-chain specific, mitochondrial precursor (MCAD) 0.0
blast CAE69691 Hypothetical protein CBG15946 [Caenorhabditis briggsae] 0.0
blast CAE57903 Hypothetical protein CBG00953 [Caenorhabditis briggsae] 0.0
Protein Families
Method ID Description E-Value
ec ACDM_DROME (Q9VSA3) Probable acyl-CoA dehydrogenase, medium-chain specific, mitochondrial precursor (EC 1.3.99.3) (MCAD) 1.0E-160
Protein Domains
Database ID Description E-Value
Pfam IPR006090 EMBL-EBI Acyl-CoA dehydrogenase, C-terminal 6.7E-74
Pfam IPR006091 EMBL-EBI Acyl-CoA dehydrogenase, central domain 2.7E-59
Pfam IPR006092 EMBL-EBI Acyl-CoA dehydrogenase, N-terminal 1.5E-26
Sequence
Target Sequence 
>C. ELEGANS:191041_S_AT
catcgttgacggtgacactcctggaatcacccgtggaaagaaggagaagaacatgggaca
gcgatgctcggacacccgtgtcatcacttttgaagacgtccgcgtgccagccgagaatgt
gctgggagcccctggagctggattcaaggtcgccatggaagcctttgacatgacgagacc
aggagttgccgccggagcacttggactctcgtggagatgtttggacgagtcggccaagta
tgctctggagagaaaggctttcggaaccgtaattgccaatcaccaagccgtccagttcat
gcttgctgacatggctgtcaacctcgagctcgctcgtcttatcacctacaaatccgccaa
cgatgtcgacaacaaggtgcgctcttcatac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CATCGTTGACGGTGACACTCCTGGA 476 211 648 Antisense
CACTCCTGGAATCACCCGTGGAAAG 215 161 663 Antisense
ACATGGGACAGCGATGCTCGGACAC 289 107 698 Antisense
TCACTTTTGAAGACGTCCGCGTGCC 298 625 731 Antisense
AGGTCGCCATGGAAGCCTTTGACAT 574 53 794 Antisense
CATGACGAGACCAGGAGTTGCCGCC 646 209 816 Antisense
GAGTCGGCCAAGTATGCTCTGGAGA 127 401 874 Antisense
CAAGCCGTCCAGTTCATGCTTGCTG 259 187 931 Antisense
GCTGACATGGCTGTCAACCTCGAGC 348 295 952 Antisense
ACAAATCCGCCAACGATGTCGACAA 431 111 995 Antisense
CGACAACAAGGTGCGCTCTTCATAC 65 253 1014 Antisense
Sequence Source Affymetrix Proprietary Database