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[191021_at] G-protein coupled receptor

Description C10C6.2 /REP_DB=WormBase Gene ID /WP=CE08056 /TR=P90745 /GB=CAB05681.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=G-protein coupled receptor
Cluster 6grp_highest_10_10 > 43      6grp_high1_10_10 > 23      4grp_highest_8_8 > 46      4grp_high_8_8 > 02      6grp_highest_nonorm > 61      6grp_total > 12      4grp_total > 14      6grp_highest_sub > 02      6grp_cgc > 52      6grp_high1_sub > 02      6grp_total_sub > Hat      6grp_rule_based > S2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 616
1 2 3 4 range
A 555.7
(1.4)
P 		240.3
(-3)
P 		295.8
(-2.2)
P 		672
(3)
P 		432
B 633.8
(2.1)
P 		242.6
(-2.6)
P 		211.9
(-3)
P 		705
(3)
P 		493
C 534.7
(-0.2)
P 		338.9
(-2.4)
P 		281.4
(-3)
P 		828.2
(3)
P 		547
avr 574.7
(1) 		273.9
(-2.9) 		263
(-3) 		735.1
(3) 		472

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 465
1 2 3 4 5 6 range
A 436.6
(3)
P 		402.8
(2.3)
P 		415.7
(2.5)
P 		430.2
(2.9)
P 		405.6
(2.3)
P 		161
(-3)
P 		276
B 413.6
(-1)
P 		625.7
(3)
P 		306.9
(-3)
P 		381.6
(-1.6)
P 		350.3
(-2.2)
P 		307.8
(-3)
P 		319
C 449.5
(0.7)
P 		559.9
(3)
P 		413.5
(-0.1)
P 		302.3
(-2.4)
P 		275.8
(-3)
P 		285.2
(-2.8)
P 		284
avr 433.2
(0.9) 		529.5
(3) 		378.7
(-0.3) 		371.4
(-0.4) 		343.9
(-1) 		251.3
(-3) 		278
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 153
1 2 3 4 range
A 202.3
(3)
P 		52.2
(-3)
P 		77.3
(-2)
P 		98.4
(-1.2)
P 		150
B 202.1
(3)
P 		59.9
(-2.6)
P 		49.1
(-3)
P 		150.2
(1)
P 		153
C 177
(3)
P 		97.4
(-3)
P 		98.1
(-2.9)
P 		139.6
(0.2)
P 		80
avr 193.8
(3) 		69.8
(-3) 		74.8
(-2.8) 		129.4
(-0.1) 		124

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 169
1 2 3 4 5 6 range
A 80.5
(-0.6)
P 		143.2
(3)
P 		90.5
(-0)
P 		109.1
(1)
P 		122.4
(1.8)
P 		39.2
(-3)
P 		104
B 143.9
(0.1)
P 		208.3
(3)
P 		74.5
(-3)
P 		101.1
(-1.8)
P 		142.3
(0)
P 		114.8
(-1.2)
P 		134
C 166.6
(2.8)
P 		170.8
(3)
P 		105.2
(-0.6)
P 		60.8
(-3)
P 		89.3
(-1.4)
P 		95.5
(-1.1)
P 		110
avr 130.3
(0.1) 		174.1
(3) 		90.1
(-2.5) 		90.3
(-2.5) 		118
(-0.7) 		83.2
(-3) 		91
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191021_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8432
Sequence Type Exemplar sequence
Representative Public ID C10C6.2 NCBI
Target Description C10C6.2 /REP_DB=WormBase Gene ID /WP=CE08056 /TR=P90745 /GB=CAB05681.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=G-protein coupled receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069761(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069761 NCBI Caenorhabditis elegans Neuropeptide Receptor family member (npr-3) (npr-3) mRNA, complete cds. 11/11 None
SNAP00000034485 ENSEMBL cdna:SNAP chromosome:CEL140:IV:11459963:11463080:1 11/11 None
GENEFINDER00000034491 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:11459963:11463080:1 11/11 None
C10C6.2 ENSEMBL cdna:known chromosome:CEL140:IV:11459963:11463147:1 gene:C10C6.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:11459968-11463086(+) 100.0 100.0
Public Domain and Genome References
Gene Title G-protein coupled receptor
Gene Symbol npr-3
Ensembl C10C6.2
Entrez Gene 182494 Entrez gene
SwissProt P90745 EMBL-EBI
WormBase CE08056 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7186 G-protein coupled receptor protein signaling pathway inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
1584 rhodopsin-like receptor activity inferred from electronic annotation QuickGO AmiGO
4983 neuropeptide Y receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB05681 Hypothetical protein C10C6.2 [Caenorhabditis elegans] ref|NP_502162.1| Neuropeptide Receptor family member (npr-3) [Caenorhabditis elegans] 0.0
blast CAE62115 Hypothetical protein CBG06153 [Caenorhabditis briggsae] 0.0
blast CAE62115 Hypothetical protein CBG06153 [Caenorhabditis briggsae] 1.0E-160
blast AAK58856 putative neuropeptide receptor NPR1 [Girardia tigrina] 4.0E-43
Protein Domains
Database ID Description E-Value
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 1.5E-56
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 5.5E-40
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_502162.1 7 30-52,72-93,100-120,140-162,197-219,251-273,286-308
C10C6.2 7 30-52,72-93,100-120,140-162,197-219,251-273,286-308
SNAP00000034485 6 28-50,54-76,89-111,146-168,202-219,234-256
GENEFINDER00000034491 7 30-52,72-93,100-120,140-162,197-219,251-273,286-308
Sequence
Target Sequence 
>C. ELEGANS:191021_AT
gaattggcctgatttcaatccggatactggaagatcgggaattcgaagagcttatggact
ttctgtgttggtacttcaatttggtattcctgcattgataagttcaatttgttactggat
gattagtcgagtgatgtcagatcaattagcaagaagaagagggcacaatattcgaccgga
atctgaaacaaagctggtgaatcgaaagacaagagctaatcgaatgatgatcgtaatggt
tgttggattcgttctcgcgtggatgccattcaatgcagtcaatctctaccgtgacctatt
tggaatttctaaatggtattctacagtctttgcgctttgccacgtatgcgcaatgtgctc
cgctgtgctcaacccaatcatctattcctggttcaatcctcaattccgacaaagtatcac
cactttgttcaagggtactgatgaagctagattgatcaagaagaaaccacaatctaccag
taaaatggtttcgtatccgactaatttctccg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAATTGGCCTGATTTCAATCCGGAT 279 323 543 Antisense
ATGGACTTTCTGTGTTGGTACTTCA 493 49 596 Antisense
TAATGGTTGTTGGATTCGTTCTCGC 405 637 776 Antisense
TTCTCGCGTGGATGCCATTCAATGC 480 693 794 Antisense
TTCAATGCAGTCAATCTCTACCGTG 505 685 811 Antisense
AATCTCTACCGTGACCTATTTGGAA 104 141 823 Antisense
ATGGTATTCTACAGTCTTTGCGCTT 232 51 855 Antisense
TCTTTGCGCTTTGCCACGTATGCGC 494 615 869 Antisense
GCTCAACCCAATCATCTATTCCTGG 466 301 909 Antisense
GTTCAATCCTCAATTCCGACAAAGT 671 445 933 Antisense
GTTTCGTATCCGACTAATTTCTCCG 132 447 1030 Antisense
Sequence Source Affymetrix Proprietary Database