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[191020_at] cobalt uptake like protein

Description T18D3.3 /REP_DB=WormBase Gene ID /WP=CE03664 /TR=Q22541 /GB=CAA92193.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=cobalt uptake like protein
Cluster 6grp_highest_10_10 > 39      6grp_high1_10_10 > 82      6grp_highest_nonorm > 71      6grp_total > 81      4grp_total > 53      6grp_highest_sub > 04      6grp_high1_sub > 04      6grp_total_sub > Hat      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 236
1 2 3 4 range
A 346.5
(2)
P 		283.4
(-0.6)
P 		371.8
(3)
P 		225
(-3)
A 		147
B 414.3
(3)
P 		342.3
(1.2)
P 		299.2
(0.1)
P 		178.6
(-3)
A 		236
C 411.4
(3)
P 		390.8
(2.1)
P 		315.7
(-1)
P 		267.6
(-3)
A 		144
avr 390.7
(3) 		338.8
(1.1) 		328.9
(0.8) 		223.7
(-3) 		167

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 310
1 2 3 4 5 6 range
A 171.8
(-3)
P 		274.3
(0.4)
P 		218.8
(-1.4)
P 		351.6
(3)
P 		338.8
(2.6)
P 		249.4
(-0.4)
P 		180
B 269.4
(-3)
P 		288.8
(-2.5)
P 		288.6
(-2.5)
P 		481.6
(3)
P 		368.9
(-0.2)
P 		342.1
(-0.9)
P 		212
C 300.3
(-2.6)
P 		311.6
(-1.9)
P 		401.7
(3)
P 		388.7
(2.3)
P 		344.6
(-0.1)
P 		292.3
(-3)
P 		109
avr 247.2
(-3) 		291.6
(-1.3) 		303
(-0.9) 		407.3
(3) 		350.8
(0.9) 		294.6
(-1.2) 		160
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 103
1 2 3 4 range
A 126.2
(3)
P 		61.5
(-1.2)
P 		97.2
(1.1)
P 		32.9
(-3)
A 		93
B 132.1
(3)
P 		84.5
(-0)
P 		69.3
(-1)
P 		38.1
(-3)
A 		94
C 136.2
(3)
P 		112.4
(1.4)
P 		110
(1.3)
P 		45.1
(-3)
A 		91
avr 131.5
(3) 		86.1
(0.1) 		92.2
(0.5) 		38.7
(-3) 		93

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 118
1 2 3 4 5 6 range
A 31.7
(-3)
P 		97.6
(2.6)
P 		47.7
(-1.6)
P 		89.2
(1.9)
P 		102.2
(3)
P 		60.7
(-0.5)
P 		71
B 93.7
(-1.2)
P 		96.1
(-1)
P 		70.1
(-3)
P 		127.6
(1.3)
P 		149.9
(3)
P 		127.6
(1.3)
P 		80
C 111.3
(3)
P 		95.1
(0)
P 		102.2
(1.3)
P 		78.2
(-3)
P 		111.5
(3)
P 		97.8
(0.5)
P 		33
avr 78.9
(-2.3) 		96.3
(-0.1) 		73.3
(-3) 		98.3
(0.1) 		121.2
(3) 		95.4
(-0.2) 		48
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191020_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16757
Sequence Type Exemplar sequence
Representative Public ID T18D3.3 NCBI
Target Description T18D3.3 /REP_DB=WormBase Gene ID /WP=CE03664 /TR=Q22541 /GB=CAA92193.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=cobalt uptake like protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077690(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077690 NCBI Caenorhabditis elegans T18D3.3 (T18D3.3) mRNA, complete cds. 11/11 None
SNAP00000005389 ENSEMBL cdna:SNAP chromosome:CEL140:X:12464690:12466698:-1 11/11 None
GENEFINDER00000005393 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:12464690:12466698:-1 11/11 None
T18D3.3 ENSEMBL cdna:known chromosome:CEL140:X:12464690:12467096:-1 gene:T18D3.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:12464689-12467096(-) 100.0 100.0
Public Domain and Genome References
Gene Title cobalt uptake like protein
Ensembl T18D3.3
Entrez Gene 188574 Entrez gene
SwissProt Q22541 EMBL-EBI
WormBase CE03664 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:251545_AT zinc transporter, putative at
CANINE:1585671_AT similar to solute carrier family 30, member 2 isoform 1 cfa
CANINE_2:CFA.5561.1.A1_AT similar to solute carrier family 30, member 2 isoform 1 cfa
CANINE_2:CFA.5561.1.A1_S_AT similar to solute carrier family 30, member 2 isoform 1 cfa
DROSOPHILA_2:1628612_AT dm
CHICKEN:GGA.10468.1.S1_AT similar to solute carrier family 30, member 2; Zink transporter 2; Solute carrier family 30 (zinc transporter), member 2; zinc transporter 2; Solute carrier family 30 (zinc transporter) member 2 gga
HG-U133_PLUS_2:224485_S_AT solute carrier family 30 (zinc transporter), member 2 hs
HG-U133B:224485_S_AT solute carrier family 30 (zinc transporter), member 2 hs
HU35KSUBA:HUM_ALU_AT solute carrier family 30 (zinc transporter), member 2 hs
HU35KSUBB:HUM_ALU_AT solute carrier family 30 (zinc transporter), member 2 hs
HU35KSUBC:HUM_ALU_AT solute carrier family 30 (zinc transporter), member 2 hs
HU35KSUBD:HUM_ALU_AT solute carrier family 30 (zinc transporter), member 2 hs
HUGENEFL:HUM_ALU_AT solute carrier family 30 (zinc transporter), member 2 hs
HC-G110:HUM_ALU_AT solute carrier family 30 (zinc transporter), member 2 hs
U133_X3P:G13623300_3P_S_AT solute carrier family 30 (zinc transporter), member 2 hs
U133_X3P:HS.143545.0.S1_3P_AT solute carrier family 30 (zinc transporter), member 2 hs
HG-U133_PLUS_2:230084_AT solute carrier family 30 (zinc transporter), member 2 hs
HG-U133B:230084_AT solute carrier family 30 (zinc transporter), member 2 hs
HG-U95E:90456_AT solute carrier family 30 (zinc transporter), member 2 hs
MOE430A:1427339_AT solute carrier family 30 (zinc transporter), member 2 mm
MOUSE430_2:1427339_AT solute carrier family 30 (zinc transporter), member 2 mm
MOUSE430A_2:1427339_AT solute carrier family 30 (zinc transporter), member 2 mm
MG-U74CV2:133053_AT solute carrier family 30 (zinc transporter), member 2 mm
RG-U34A:U50927_AT solute carrier family 30 (zinc transporter), member 2 rn
RAE230A:1398264_AT solute carrier family 30 (zinc transporter), member 2 rn
RAT230_2:1398264_AT solute carrier family 30 (zinc transporter), member 2 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6812 cation transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8324 cation transporter activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92193 Hypothetical protein T18D3.3 [Caenorhabditis elegans] ref|NP_510091.1| T18D3.3 [Caenorhabditis elegans] 0.0
blast CAE57243 Hypothetical protein CBG00121 [Caenorhabditis briggsae] 1.0E-175
blast CAE57243 Hypothetical protein CBG00121 [Caenorhabditis briggsae] 1.0E-169
blast AAH76884 Solute carrier family 30 (zinc transporter), member 3 [Xenopus tropicalis] ref|NP_001006823.1| solute carrier family 30 (zinc transporter), member 3 [Xenopus tropicalis] 4.0E-87
Protein Domains
Database ID Description E-Value
Pfam IPR002524 EMBL-EBI Cation efflux protein 2.5E-101
Pfam IPR002524 EMBL-EBI Cation efflux protein 2.5E-101
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_510091.1 6 75-97,107-126,147-169,179-201,231-253,258-280
T18D3.3 6 75-97,107-126,147-169,179-201,231-253,258-280
SNAP00000005389 6 53-75,85-104,125-147,157-179,209-231,236-258
GENEFINDER00000005393 6 53-75,85-104,125-147,157-179,209-231,236-258
Sequence
Target Sequence 
>C. ELEGANS:191020_AT
gacagccgctcttggagtggttgtaaacttggtcatgcttgcattgttgtactttggtgg
tcattcacattctcacggaggcggaagctctcatggtcactctcatggtggtggcaacgg
cgataacatcaacgtccgagcagcttttattcacgttctgggagaccttttacaaagttt
gggcgttcttgttgctgccctttttatctatttccagccgtcttgggttattattgatcc
aatttgtacacttgttttctcggttattgtgctatgcaccactatctacatattgagaga
tgctatgattgttttattggaaggtagacctagcaacattgactttgcgaaagtattttc
gtcccttgaagatatagaaggtgttaaaaaggttcatgacttgagaatttggagtttgac
gatggacaagattgcactctccgtacacttggaaattgacgccaatagtcaatctcagtc
aattctacgcga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GACAGCCGCTCTTGGAGTGGTTGTA 77 369 558 Antisense
TGGTGGTCATTCACATTCTCACGGA 285 553 612 Antisense
TGGTCACTCTCATGGTGGTGGCAAC 81 553 651 Antisense
ACATCAACGTCCGAGCAGCTTTTAT 707 105 683 Antisense
GCTTTTATTCACGTTCTGGGAGACC 427 303 700 Antisense
TGCTGCCCTTTTTATCTATTTCCAG 247 583 750 Antisense
CTATTTCCAGCCGTCTTGGGTTATT 424 219 765 Antisense
TGTACACTTGTTTTCTCGGTTATTG 448 559 802 Antisense
TTGTGCTATGCACCACTATCTACAT 38 705 824 Antisense
TGGACAAGATTGCACTCTCCGTACA 529 547 980 Antisense
GTCAATCTCAGTCAATTCTACGCGA 672 463 1025 Antisense
Sequence Source Affymetrix Proprietary Database