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[191010_s_at] channel protein

Description M60.5 /REP_DB=WormBase Gene ID /WP=CE02834 /GEN=klq-2 /TR=Q9GYM8 /GB=AAF99993.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=channel protein
Cluster 6grp_highest_10_10 > 66      6grp_high1_10_10 > 65      4grp_highest_8_8 > 22      4grp_high_8_8 > 07      6grp_highest_nonorm > 90      6grp_total > 66      4grp_total > 0      6grp_highest_sub > Da      6grp_cgc > 47      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 142
1 2 3 4 range
A 128.1
(-3)
P 		130
(-2.9)
P 		128.2
(-3)
P 		217.2
(3)
P 		89
B 137.2
(-3)
P 		141.9
(-2.8)
P 		165.4
(-1.5)
P 		250.6
(3)
P 		113
C 164.3
(-1.3)
P 		124.1
(-3)
P 		162.1
(-1.4)
P 		266.5
(3)
P 		142
avr 143.2
(-2.4) 		132
(-3) 		151.9
(-1.9) 		244.8
(3) 		113

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 93
1 2 3 4 5 6 range
A 82.1
(-3)
P 		117.1
(0.6)
P 		93.3
(-1.9)
P 		110.5
(-0.1)
P 		110.5
(-0.1)
P 		140.7
(3)
P 		59
B 135.1
(2.1)
P 		119.4
(-0.8)
P 		114.3
(-1.8)
P 		110.4
(-2.5)
P 		107.9
(-3)
P 		139.6
(3)
P 		32
C 116.9
(-1.8)
P 		102.4
(-3)
P 		175.1
(3)
P 		123.7
(-1.2)
P 		102.1
(-3)
P 		161.8
(1.9)
P 		73
avr 111.4
(-2.3) 		113
(-2.1) 		127.6
(0.1) 		114.9
(-1.8) 		106.8
(-3) 		147.4
(3) 		41
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 28
1 2 3 4 range
A 46.6
(3)
P 		28.2
(-3)
P 		33.5
(-1.3)
P 		31.8
(-1.8)
P 		18
B 43.7
(-0.2)
P 		35.1
(-3)
P 		38.3
(-2)
P 		53.4
(3)
P 		18
C 54.4
(2.4)
P 		35.7
(-3)
P 		56.5
(3)
P 		44.9
(-0.3)
P 		21
avr 48.2
(3) 		33
(-3) 		42.8
(0.9) 		43.4
(1.1) 		15

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 39
1 2 3 4 5 6 range
A 15.1
(-3)
P 		41.7
(3)
P 		20.3
(-1.8)
P 		28
(-0.1)
P 		33.4
(1.1)
P 		34.2
(1.3)
P 		27
B 47
(1.7)
P 		39.7
(-0)
P 		27.7
(-3)
P 		29.2
(-2.6)
P 		43.8
(1)
P 		52.1
(3)
P 		24
C 43.3
(0.8)
P 		31.2
(-1.7)
P 		44.6
(1)
P 		24.9
(-3)
P 		33
(-1.3)
P 		54.2
(3)
P 		29
avr 35.1
(-0.6) 		37.5
(0.1) 		30.9
(-1.9) 		27.4
(-3) 		36.7
(-0.1) 		46.8
(3) 		19
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191010_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16208
Sequence Type Exemplar sequence
Representative Public ID M60.5 NCBI
Target Description M60.5 /REP_DB=WormBase Gene ID /WP=CE02834 /GEN=klq-2 /TR=Q9GYM8 /GB=AAF99993.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=channel protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076991(9)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076991 NCBI Caenorhabditis elegans potassium channel, KvQLT family member (kqt-2) (kqt-2) mRNA, complete cds. 9/11 None
SNAP00000012321 ENSEMBL cdna:SNAP chromosome:CEL140:X:8243286:8246193:-1 9/11 None
GENEFINDER00000012331 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:8243286:8246171:-1 9/11 None
M60.5 ENSEMBL cdna:known chromosome:CEL140:X:8243073:8246307:-1 gene:M60.5 9/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:8243284-8246306(-) 100.0 100.0
Public Domain and Genome References
Gene Title channel protein
Gene Symbol kqt-2
Ensembl M60.5
Entrez Gene 181078 Entrez gene
SwissProt Q9GYM8 EMBL-EBI
WormBase CE30291 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6811 ion transport inferred from electronic annotation QuickGO AmiGO
6813 potassium ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
8076 voltage-gated potassium channel complex inferred from electronic annotation QuickGO AmiGO
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5216 ion channel activity inferred from electronic annotation QuickGO AmiGO
5249 voltage-gated potassium channel activity inferred from electronic annotation QuickGO AmiGO
5249 voltage-gated potassium channel activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAF99993 Potassium channel, kvqlt family protein 2 [Caenorhabditis elegans] ref|NP_509392.2| potassium channel, KvQLT family member (kqt-2) [Caenorhabditis elegans] 0.0
blast T28852 probable potassium channel - Caenorhabditis elegans 0.0
blast CAE74864 Hypothetical protein CBG22719 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR005821 EMBL-EBI Ion transport protein 2.6E-11
Pfam IPR005821 EMBL-EBI Ion transport protein 2.6E-11
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_509392.2 5 88-110,125-147,160-182,227-249,299-321
M60.5 5 88-110,125-147,160-182,227-249,299-321
SNAP00000012321 4 65-87,133-155,175-197,204-226
GENEFINDER00000012331 5 21-43,53-75,88-110,155-177,227-249
Sequence
Target Sequence 
>C. ELEGANS:191010_S_AT
tctgttgaaacttcgatgtcctcctctgttgatgtatccgagttggagactcaatttgaa
ataaccaactttcttgaacagaatgtcgatgagcttagctcaaaaggtaaccaatctggg
cggagtttgctctggaagccacagggctcaaccttagcgcagacccaacgtatcgccggt
caactccttatgattgaagccgaaatcgccgaaagggaaaatcagcgcaatcagaaaatg
aaagaactggaagctgcaattttagagctcactggaaagccaaccgtctcgccttttgac
gattccggacagaagttgtcaatcattgaacgtttggagttttgtgaaaaacgaatggaa
gatttggaacggaaaaccgatgcattgaacgaaatcaccatcaagtgtctcaacttaatg
atgatggacacccaagaagctgcgtcaaggacaaaggacgagcaaggtcttccgccaaaa
cctccaagtgctaacaacaaaaaacaaagaaccattggaccgagacgccaggtcacaatt
gtcgaccagtacgacacgctcgac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCTGTTGAAACTTCGATGTCCTCCT 559 607 1411 Antisense
TCCTCCTCTGTTGATGTATCCGAGT 593 591 1429 Antisense
GGGCGGAGTTTGCTCTGGAAGCCAC 327 493 1528 Antisense
CCTTAGCGCAGACCCAACGTATCGC 248 265 1562 Antisense
AGAGCTCACTGGAAAGCCAACCGTC 486 69 1674 Antisense
TCGCCTTTTGACGATTCCGGACAGA 86 599 1699 Antisense
AAAGGACGAGCAAGGTCTTCCGCCA 469 121 1863 Antisense
GCCAAAACCTCCAAGTGCTAACAAC 540 277 1884 Antisense
AAGAACCATTGGACCGAGACGCCAG 652 151 1917 Antisense
GAGACGCCAGGTCACAATTGTCGAC 59 393 1932 Antisense
TGTCGACCAGTACGACACGCTCGAC 656 557 1950 Antisense
Sequence Source Affymetrix Proprietary Database