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[190986_at] alpha/beta hydrolase fold

Description R05D7.4 /REP_DB=WormBase Gene ID /WP=CE18906 /TR=O45707 /GB=CAB03219.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=alpha-beta hydrolase fold
Cluster 6grp_highest_10_10 > 53      6grp_high1_10_10 > 34      4grp_highest_8_8 > 25      4grp_high_8_8 > 60      6grp_highest_nonorm > 72      6grp_total > 01      4grp_total > 60      6grp_highest_sub > 02      6grp_high1_sub > 02      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 403
1 2 3 4 range
A 539.2
(0.9)
P 		526.1
(0.7)
P 		683.4
(3)
P 		280.7
(-3)
P 		403
B 550.7
(2.2)
P 		580.3
(3)
P 		545.9
(2.1)
P 		354.4
(-3)
P 		226
C 558.2
(0.5)
P 		553.6
(0.4)
P 		641.8
(3)
P 		440.6
(-3)
P 		201
avr 549.4
(1.3) 		553.3
(1.4) 		623.7
(3) 		358.6
(-3) 		265

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 205
1 2 3 4 5 6 range
A 377.7
(-3)
P 		582.6
(3)
P 		525.4
(1.3)
P 		514.5
(1)
P 		410.4
(-2)
P 		414.1
(-1.9)
P 		205
B 481.8
(0.7)
P 		486.1
(0.8)
P 		400.5
(-2.2)
P 		378
(-3)
P 		546.5
(3)
P 		486.8
(0.9)
P 		169
C 522.3
(3)
P 		466.5
(-0)
P 		492.2
(1.4)
P 		411
(-3)
P 		469.7
(0.2)
P 		514.5
(2.6)
P 		111
avr 460.6
(-1) 		511.7
(3) 		472.7
(-0) 		434.5
(-3) 		475.5
(0.2) 		471.8
(-0.1) 		77
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 183
1 2 3 4 range
A 196.3
(3)
P 		114.2
(-0.2)
P 		178.7
(2.3)
P 		41.1
(-3)
P 		155
B 175.6
(3)
P 		143.3
(1.1)
P 		126.5
(0.1)
P 		75.5
(-3)
P 		100
C 184.8
(1.4)
P 		159.2
(0.4)
P 		223.7
(3)
P 		74.3
(-3)
P 		149
avr 185.6
(3) 		138.9
(0.7) 		176.3
(2.5) 		63.6
(-3) 		122

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 152
1 2 3 4 5 6 range
A 69.6
(-3)
P 		207.2
(3)
P 		114.4
(-1)
P 		130.5
(-0.3)
P 		123.8
(-0.6)
P 		100.8
(-1.6)
P 		138
B 167.6
(0.4)
P 		161.8
(0.1)
P 		97.3
(-3)
P 		100.1
(-2.9)
P 		222
(3)
P 		181.5
(1.1)
P 		125
C 193.6
(3)
P 		142.3
(0.2)
P 		125.3
(-0.7)
P 		82.6
(-3)
P 		152
(0.8)
P 		172.2
(1.8)
P 		111
avr 143.6
(0.6) 		170.4
(3) 		112.3
(-2.3) 		104.4
(-3) 		165.9
(2.6) 		151.5
(1.3) 		66
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190986_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2470
Sequence Type Exemplar sequence
Representative Public ID R05D7.4 NCBI
Target Description R05D7.4 /REP_DB=WormBase Gene ID /WP=CE18906 /TR=O45707 /GB=CAB03219.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=alpha-beta hydrolase fold
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060676(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060676 NCBI Caenorhabditis elegans R05D7.4 (R05D7.4) mRNA, complete cds. 11/11 None
SNAP00000020576 ENSEMBL cdna:SNAP chromosome:CEL140:I:12186552:12191144:-1 11/11 None
R05D7.4 ENSEMBL cdna:known chromosome:CEL140:I:12189200:12191290:-1 gene:R05D7.4 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000020578 6/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:12189171-12191221(-) 100.0 100.0
Public Domain and Genome References
Gene Title alpha/beta hydrolase fold
Ensembl R05D7.4
Entrez Gene 173096 Entrez gene
SwissProt O45707 EMBL-EBI
WormBase CE18906 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.19542.1.S1_AT similar to abhydrolase domain containing 11 isoform 2 cfa
DROSOPHILA_2:1635215_AT dm
DROSGENOME1:144644_AT dm
HG-U133_PLUS_2:221927_S_AT abhydrolase domain containing 11 hs
HG-U133A_2:221927_S_AT abhydrolase domain containing 11 hs
HG-U133A:221927_S_AT abhydrolase domain containing 11 hs
HU35KSUBD:RC_AA427636_AT abhydrolase domain containing 11 hs
U133_X3P:HS2.182476.3.S1_3P_AT abhydrolase domain containing 11 hs
U133_X3P:HS2.182476.1.S1_3P_S_AT abhydrolase domain containing 11 hs
U133_X3P:HS.182476.0.A1_3P_S_AT abhydrolase domain containing 11 hs
HG-U133_PLUS_2:1552470_A_AT abhydrolase domain containing 11 hs
HG-U133_PLUS_2:1552800_AT abhydrolase domain containing 11 hs
HG-U95B:54850_AT abhydrolase domain containing 11 hs
MG-U74BV2:107050_AT abhydrolase domain containing 11 mm
MG-U74BV2:107049_AT abhydrolase domain containing 11 mm
MG-U74CV2:165420_AT abhydrolase domain containing 11 mm
MOE430B:1428428_AT abhydrolase domain containing 11 mm
MOUSE430_2:1428428_AT abhydrolase domain containing 11 mm
MU19KSUBA:TC18172_AT Abhydrolase domain containing 11 (Abhd11), mRNA mm
MU19KSUBB:TC34422_AT Abhydrolase domain containing 11 (Abhd11), mRNA mm
MU19KSUBB:TC34422_G_AT Abhydrolase domain containing 11 (Abhd11), mRNA mm
RG-U34B:RC_AI011306_AT Williams Beuren syndrome chromosome region 21 (predicted) rn
RAE230A:1399083_AT Williams Beuren syndrome chromosome region 21 (predicted) rn
RAT230_2:1399083_AT Williams Beuren syndrome chromosome region 21 (predicted) rn
RG-U34B:RC_AI011306_AT similar to Williams-Beuren syndrome critical region protein 21 rn
RAE230A:1399083_AT similar to Williams-Beuren syndrome critical region protein 21 rn
RAT230_2:1399083_AT similar to Williams-Beuren syndrome critical region protein 21 rn
RAE230B:1393358_AT Williams Beuren syndrome chromosome region 21 (predicted) rn
RAT230_2:1393358_AT Williams Beuren syndrome chromosome region 21 (predicted) rn
RG-U34B:RC_AA944779_AT Williams Beuren syndrome chromosome region 21 (predicted) rn
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
3824 catalytic activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB03219 Hypothetical protein R05D7.4 [Caenorhabditis elegans] ref|NP_493077.1| R05D7.4 [Caenorhabditis elegans] 1.0E-173
blast CAB03219 Hypothetical protein R05D7.4 [Caenorhabditis elegans] ref|NP_493077.1| R05D7.4 [Caenorhabditis elegans] 1.0E-150
blast CAE72990 Hypothetical protein CBG20335 [Caenorhabditis briggsae] 1.0E-139
blast CAE72990 Hypothetical protein CBG20335 [Caenorhabditis briggsae] 1.0E-128
blast CAB04232 Hypothetical protein F32B4.6 [Caenorhabditis elegans] ref|NP_492942.1| F32B4.6 [Caenorhabditis elegans] 8.0E-54
blast CAB04232 Hypothetical protein F32B4.6 [Caenorhabditis elegans] ref|NP_492942.1| F32B4.6 [Caenorhabditis elegans] 2.0E-52
Sequence
Target Sequence 
>C. ELEGANS:190986_AT
tcacccaagggatattccaggcggcatttagaattccgagagctcatcaaaaccatgcga
aacgtggatctttgtcgcactcgaaaggaaattctcaaggatcttgaatcggcgattcca
gacttggcaatgcgccaatttattctcacaaatttgcagccgtcgagtgaaaatgagggg
caaatggagtggaaaatcaatattaatacgatcgatagccatgtggatgagattttggga
tataccctcccagttggcagtttccgaggccccactctctttctccacggagcaaattca
ggatatgttccagacgatcataaacccgatattaaatgcctttttccacaggtccaattc
gacgcgattccggactctggccactgggttcacgctgaaaaacctcaacttt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCACCCAAGGGATATTCCAGGCGGC 218 625 466 Antisense
TCCGAGAGCTCATCAAAACCATGCG 590 595 500 Antisense
GAAACGTGGATCTTTGTCGCACTCG 97 359 524 Antisense
GCGATTCCAGACTTGGCAATGCGCC 447 291 577 Antisense
GCAATGCGCCAATTTATTCTCACAA 537 321 592 Antisense
ATTCTCACAAATTTGCAGCCGTCGA 348 11 607 Antisense
TTTGGGATATACCCTCCCAGTTGGC 363 661 699 Antisense
TGTTCCAGACGATCATAAACCCGAT 69 563 771 Antisense
AATGCCTTTTTCCACAGGTCCAATT 643 165 800 Antisense
GGTCCAATTCGACGCGATTCCGGAC 549 499 816 Antisense
GTTCACGCTGAAAAACCTCAACTTT 622 443 853 Antisense
Sequence Source Affymetrix Proprietary Database