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[190973_at] alpha/beta hydrolase fold

Description C46C2.4 /REP_DB=WormBase Gene ID /WP=CE03083 /TR=Q18656 /GB=CAA92590.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=alpha-beta hydrolase fold
Cluster 6grp_total > 53      4grp_total > 26      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 63
1 2 3 4 range
A 42.2
(-2.8)
M 		54.3
(-1.3)
A 		40.8
(-3)
A 		89.3
(3)
P 		49
B 30.7
(-1.2)
A 		37.1
(1.3)
A 		26.1
(-3)
A 		41.3
(3)
P 		15
C 31.8
(-3)
P 		51.6
(2.3)
A 		40.7
(-0.6)
A 		54.3
(3)
A 		23
avr 34.9
(-3) 		47.7
(-0.1) 		35.9
(-2.8) 		61.6
(3) 		27

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 46
1 2 3 4 5 6 range
A 43.2
(3)
A 		27.9
(-0.9)
A 		40.1
(2.2)
A 		19.8
(-3)
A 		24.1
(-1.9)
M 		39
(1.9)
A 		23
B 29.6
(-2.2)
P 		33.8
(-1.5)
A 		63.1
(3)
P 		24.2
(-3)
A 		24.7
(-2.9)
A 		41.5
(-0.3)
P 		39
C 20.1
(-2.6)
A 		49.2
(1.4)
M 		27.8
(-1.5)
A 		57.3
(2.5)
P 		61.2
(3)
A 		17.1
(-3)
A 		44
avr 31
(-3) 		37
(-0.2) 		43.7
(3) 		33.8
(-1.7) 		36.7
(-0.3) 		32.5
(-2.3) 		13
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 9
1 2 3 4 range
A 15.4
(3)
M 		11.8
(-1.6)
A 		10.7
(-3)
A 		13.1
(0.1)
P 		5
B 9.8
(3)
A 		9.2
(2.1)
A 		6
(-3)
A 		8.8
(1.4)
P 		4
C 10.5
(-1.6)
P 		14.8
(3)
A 		14.2
(2.4)
A 		9.2
(-3)
A 		6
avr 11.9
(3) 		11.9
(3) 		10.3
(-3) 		10.4
(-2.6) 		2

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 15
1 2 3 4 5 6 range
A 8
(0.7)
A 		9.9
(3)
A 		8.7
(1.5)
A 		5
(-3)
A 		7.3
(-0.2)
M 		9.5
(2.5)
A 		5
B 10.3
(-0.4)
P 		11.2
(0.2)
A 		15.3
(2.9)
P 		6.4
(-3)
A 		10
(-0.6)
A 		15.5
(3)
P 		9
C 7.5
(-2.2)
A 		15
(1)
M 		7.1
(-2.4)
A 		11.5
(-0.5)
P 		19.8
(3)
A 		5.7
(-3)
A 		14
avr 8.6
(-1.8) 		12
(2.5) 		10.4
(0.5) 		7.6
(-3) 		12.4
(3) 		10.2
(0.2) 		5
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190973_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9699
Sequence Type Exemplar sequence
Representative Public ID C46C2.4 NCBI
Target Description C46C2.4 /REP_DB=WormBase Gene ID /WP=CE03083 /TR=Q18656 /GB=CAA92590.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=alpha-beta hydrolase fold
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069200(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069200 NCBI Caenorhabditis elegans C46C2.4 (C46C2.4) mRNA, complete cds. 11/11 None
SNAP00000024419 ENSEMBL cdna:SNAP chromosome:CEL140:IV:9189108:9191101:1 11/11 None
C46C2.4 ENSEMBL cdna:known chromosome:CEL140:IV:9186795:9191101:1 gene:C46C2.4 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000024429 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:9186800-9191107(+) 100.0 100.0
Public Domain and Genome References
Gene Title alpha/beta hydrolase fold
Ensembl C46C2.4
Entrez Gene 183503 Entrez gene
SwissProt Q18656 EMBL-EBI
WormBase CE03083 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8236 serine-type peptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92590 Hypothetical protein C46C2.4 [Caenorhabditis elegans] ref|NP_501601.1| C46C2.4 [Caenorhabditis elegans] 0.0
blast CAB05185 Hypothetical protein F23B2.11 [Caenorhabditis elegans] ref|NP_501598.1| Prolyl Carboxy Peptidase like family member (pcp-3) [Caenorhabditis elegans] 1.0E-117
blast CAE74127 Hypothetical protein CBG21793 [Caenorhabditis briggsae] 1.0E-115
blast CAB05185 Hypothetical protein F23B2.11 [Caenorhabditis elegans] ref|NP_501598.1| Prolyl Carboxy Peptidase like family member (pcp-3) [Caenorhabditis elegans] 1.0E-111
blast CAE74127 Hypothetical protein CBG21793 [Caenorhabditis briggsae] 1.0E-110
Protein Domains
Database ID Description E-Value
Pfam IPR008758 EMBL-EBI Peptidase S28 1.8E-21
Pfam IPR008758 EMBL-EBI Peptidase S28 6.4E-17
Pfam IPR008758 EMBL-EBI Peptidase S28 3.7E-81
Pfam IPR008758 EMBL-EBI Peptidase S28 7.3E-58
Pfam IPR008758 EMBL-EBI Peptidase S28 3.1E-95
Pfam IPR008758 EMBL-EBI Peptidase S28 7.3E-58
Sequence
Target Sequence 
>C. ELEGANS:190973_AT
aagtgtccaatacgctggatacggtagtggtgcatttgcaaagacatcgaagaagttgaa
gaacaaaccaaaaggtgatgtagacaaccaaaacgatgatatatccactgaaaacgacgg
tctactttggatgtggcaaacatgtacagaattcgggttttatcaatccactgacactgg
aaattctatttttggaaatgtaccagtcagttattttgtgcaacaatgcatggatctgtt
tggcaataattacacacgagcaacaattgataaacaagtagggaggacaaatcataagta
cgatggaacttatgagttcaatgcaacaaatgtagttttcctaaatggagatgctgatcc
atggagtccacttggactaaaaaactcaactgatccatcagttgtctcatttttaattaa
tggaacttctcattgtgtagatatgtattcagaaacagaagatgatcttcctgatttgaa
aaccgcacgaaaaatagttgatgaaaatattgaaaagtggttgaattcgactacgacgac
caaatcacccaattctgcaaattacccacgtgctctaaattcttta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAGTGTCCAATACGCTGGATACGGT 115 159 1239 Antisense
GGATACGGTAGTGGTGCATTTGCAA 20 511 1255 Antisense
ATATCCACTGAAAACGACGGTCTAC 499 19 1339 Antisense
ACGACGGTCTACTTTGGATGTGGCA 470 91 1352 Antisense
GAATTCGGGTTTTATCAATCCACTG 535 323 1387 Antisense
GATGCTGATCCATGGAGTCCACTTG 237 415 1588 Antisense
CTGATCCATCAGTTGTCTCATTTTT 142 239 1628 Antisense
GGTTGAATTCGACTACGACGACCAA 159 501 1757 Antisense
GACCAAATCACCCAATTCTGCAAAT 706 383 1776 Antisense
AATTCTGCAAATTACCCACGTGCTC 413 177 1789 Antisense
TTACCCACGTGCTCTAAATTCTTTA 483 679 1800 Antisense
Sequence Source Affymetrix Proprietary Database