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[190966_at] glutathione peroxidase

Description C11E4.2 /REP_DB=WormBase Gene ID /WP=CE08102 /TR=SW:Q95003 /GB=CAB02655.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=glutathione peroxidase
Cluster 6grp_highest_10_10 > 62      6grp_high1_10_10 > 29      4grp_highest_8_8 > 47      4grp_high_8_8 > 11      6grp_highest_nonorm > 50      6grp_total > 26      4grp_total > 13      6grp_highest_sub > Cu      6grp_high1_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2197
1 2 3 4 range
A 1918.8
(0.3)
P 		1576.6
(-0.8)
P 		859.6
(-3)
P 		2787.4
(3)
P 		1928
B 2100
(0.3)
P 		1295.8
(-2)
P 		953.9
(-3)
P 		3011
(3)
P 		2057
C 1890.2
(0.3)
P 		1404.2
(-1.2)
P 		814.2
(-3)
P 		2790.3
(3)
P 		1976
avr 1969.7
(0.3) 		1425.5
(-1.3) 		875.9
(-3) 		2862.9
(3) 		1987

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 512
1 2 3 4 5 6 range
A 804.2
(3)
P 		759.9
(2.4)
P 		380.6
(-2.6)
P 		354.1
(-3)
P 		421.5
(-2.1)
P 		535.1
(-0.6)
P 		450
B 570.8
(1.6)
P 		657.2
(3)
P 		292.3
(-3)
P 		351.8
(-2)
P 		523.5
(0.8)
P 		456.2
(-0.3)
P 		365
C 626.7
(2.6)
P 		648.2
(3)
P 		410
(-1.9)
P 		358.8
(-3)
P 		554.2
(1.1)
P 		546.8
(0.9)
P 		289
avr 667.2
(2.6) 		688.4
(3) 		361
(-2.9) 		354.9
(-3) 		499.7
(-0.4) 		512.7
(-0.2) 		334
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 478
1 2 3 4 range
A 698.6
(3)
P 		342.2
(-1.5)
P 		224.7
(-3)
P 		408
(-0.7)
P 		474
B 669.7
(3)
P 		320
(-1.7)
P 		221
(-3)
P 		641.6
(2.6)
P 		449
C 625.7
(3)
P 		403.7
(-0.9)
P 		283.8
(-3)
P 		470.5
(0.3)
P 		342
avr 664.7
(3) 		355.3
(-1.4) 		243.2
(-3) 		506.7
(0.8) 		422

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 199
1 2 3 4 5 6 range
A 148.3
(-0.9)
P 		270.3
(3)
P 		82.9
(-3)
P 		89.8
(-2.8)
P 		127.2
(-1.6)
P 		130.3
(-1.5)
P 		187
B 198.6
(2.2)
P 		218.8
(3)
P 		71
(-3)
P 		93.2
(-2.1)
P 		212.7
(2.8)
P 		170.1
(1)
P 		148
C 232.3
(3)
P 		197.8
(1.7)
P 		104.3
(-1.8)
P 		72.2
(-3)
P 		179.3
(1)
P 		183.1
(1.2)
P 		160
avr 193.1
(1.5) 		229
(3) 		86.1
(-3) 		85.1
(-3) 		173.1
(0.7) 		161.2
(0.2) 		144
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190966_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16971
Sequence Type Exemplar sequence
Representative Public ID C11E4.2 NCBI
Target Description C11E4.2 /REP_DB=WormBase Gene ID /WP=CE08102 /TR=SW:Q95003 /GB=CAB02655.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=glutathione peroxidase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077215(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077215 NCBI Caenorhabditis elegans C11E4.2 (C11E4.2) mRNA, complete cds. 11/11 None
SNAP00000031374 ENSEMBL cdna:SNAP chromosome:CEL140:X:9587890:9588705:1 10/11 None
GENEFINDER00000031380 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:9587890:9588705:1 11/11 None
C11E4.2 ENSEMBL cdna:known chromosome:CEL140:X:9587890:9588705:1 gene:C11E4.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:9587889-9588705(+) 100.0 100.0
Public Domain and Genome References
Gene Title glutathione peroxidase
Ensembl C11E4.2
Entrez Gene 182513 Entrez gene
SwissProt Q95003 EMBL-EBI
WormBase CE08102 Wormbase
Functional Annotations
Ortholog
ID Title Organism
MG-U74BV2:163737_AT glutathione peroxidase 6 mm
MOE430A:1452135_AT glutathione peroxidase 6 mm
MOUSE430A_2:1452135_AT glutathione peroxidase 6 mm
MOUSE430_2:1452135_AT glutathione peroxidase 6 mm
RG-U34A:M76733_AT glutathione peroxidase 6 rn
RAE230A:1388085_AT glutathione peroxidase 6 rn
RAT230_2:1388085_AT glutathione peroxidase 6 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6979 response to oxidative stress inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4602 glutathione peroxidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB02655 Hypothetical protein C11E4.2 [Caenorhabditis elegans] ref|NP_509616.1| C11E4.2 [Caenorhabditis elegans] sp|Q95003|GPX3_CAEEL Glutathione peroxidase precursor 1.0E-132
blast CAB02655 Hypothetical protein C11E4.2 [Caenorhabditis elegans] ref|NP_509616.1| C11E4.2 [Caenorhabditis elegans] sp|Q95003|GPX3_CAEEL Glutathione peroxidase precursor 1.0E-119
blast CAE69790 Hypothetical protein CBG16081 [Caenorhabditis briggsae] 1.0E-108
blast CAE69790 Hypothetical protein CBG16081 [Caenorhabditis briggsae] 1.0E-107
blast AAT28332 glutathione peroxidase [Haemonchus contortus] 1.0E-98
Protein Domains
Database ID Description E-Value
Pfam IPR000889 EMBL-EBI Glutathione peroxidase 2.4E-62
Pfam IPR000889 EMBL-EBI Glutathione peroxidase 2.4E-62
Sequence
Target Sequence 
>C. ELEGANS:190966_AT
ttattggtatctcttgcactgcaacggttgatgaaacaatgcgttggaaagaatgtttga
atacaaatcaaagcatattcgactttcaaattgaaactttgcaaggagaatacacagatc
ttagtcagtaccgaggaaaagtaattcttctcgtcaatgttgcaacattctgtgcataca
ctcaacagtacactgacttcaaccccatgcttgaaaaatatcaagctcaggggcttacgc
ttgttgccttcccatgcaatcagttctacctgcaagagccagcagagaaccacgagctta
tgaacgggcttacctatgtgcgccctggaaatggatggactccacatcaagagcttcata
tctatggtaaaattgatgtgaacggagacaatcatcacccactttacgagtttgttaagg
agtcttgcccacaaactgttgacaaaattggaaaaactgacgagttgatgtacaaccctg
ttcggccatccgatatcacat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTATTGGTATCTCTTGCACTGCAAC 579 677 59 Antisense
ACACAGATCTTAGTCAGTACCGAGG 580 111 170 Antisense
GTAATTCTTCTCGTCAATGTTGCAA 489 463 199 Antisense
CTGACTTCAACCCCATGCTTGAAAA 562 237 251 Antisense
ATCAGTTCTACCTGCAAGAGCCAGC 210 29 317 Antisense
GAGCCAGCAGAGAACCACGAGCTTA 463 385 334 Antisense
TATGAACGGGCTTACCTATGTGCGC 117 657 357 Antisense
GTGCGCCCTGGAAATGGATGGACTC 595 477 376 Antisense
ATCATCACCCACTTTACGAGTTTGT 193 29 449 Antisense
GAGTTGATGTACAACCCTGTTCGGC 310 397 520 Antisense
CCTGTTCGGCCATCCGATATCACAT 157 267 535 Antisense
Sequence Source Affymetrix Proprietary Database