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[190963_at] nuclear hormone receptor

Description C17E7.5 /REP_DB=WormBase Gene ID /WP=CE08265 /TR=O16388 /GB=AAC24277.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=nuclear hormone receptor
Cluster 6grp_total > 42      4grp_total > 03      6grp_cgc > 81      6grp_cgc_sub > 03      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 100
1 2 3 4 range
A 3.2
(-3)
A 		3.1
(-3)
A 		3.2
(-3)
A 		59.5
(3)
A 		56
B 27
(3)
A 		1.4
(-3)
A 		3.8
(-2.4)
A 		2.4
(-2.8)
A 		26
C 19.6
(-2.8)
A 		17.3
(-3)
A 		17.9
(-3)
A 		101.3
(3)
P 		84
avr 16.6
(-1.8) 		7.3
(-3) 		8.3
(-2.9) 		54.4
(3) 		47

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 47
1 2 3 4 5 6 range
A 30.5
(3)
A 		1.2
(-3)
A 		7.5
(-1.7)
A 		4.5
(-2.3)
A 		8.7
(-1.5)
A 		2
(-2.8)
A 		29
B 4.7
(-2.6)
A 		4.2
(-2.6)
A 		48.3
(3)
A 		21.8
(-0.4)
A 		15
(-1.2)
A 		1.2
(-3)
A 		47
C 0.9
(-3)
A 		24.6
(3)
A 		8
(-1.2)
A 		2.2
(-2.7)
A 		1.3
(-2.9)
A 		2.1
(-2.7)
A 		24
avr 12
(0.1) 		10
(-0.5) 		21.3
(3) 		9.5
(-0.6) 		8.3
(-1) 		1.8
(-3) 		20
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 17
1 2 3 4 range
A 1.2
(-2.6)
A 		0.7
(-3)
A 		0.8
(-2.9)
A 		8.7
(3)
A 		8
B 8.6
(3)
A 		0.3
(-3)
A 		0.9
(-2.6)
A 		0.5
(-2.9)
A 		8
C 6.5
(-2.3)
A 		5
(-3)
A 		6.2
(-2.4)
A 		17.1
(3)
P 		12
avr 5.4
(0) 		2
(-3) 		2.6
(-2.5) 		8.8
(3) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 11
1 2 3 4 5 6 range
A 5.6
(3)
A 		0.4
(-3)
A 		1.6
(-1.6)
A 		1.1
(-2.2)
A 		2.6
(-0.5)
A 		0.5
(-2.9)
A 		5
B 1.6
(-2.4)
A 		1.4
(-2.5)
A 		11.7
(3)
A 		5.8
(-0.2)
A 		6.1
(-0)
A 		0.5
(-3)
A 		11
C 0.3
(-3)
A 		7.5
(3)
A 		2
(-1.6)
A 		0.4
(-2.9)
A 		0.4
(-2.9)
A 		0.7
(-2.7)
A 		7
avr 2.5
(-0.5) 		3.1
(0.3) 		5.1
(3) 		2.4
(-0.6) 		3
(0.2) 		0.6
(-3) 		5
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190963_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.15507
Sequence Type Exemplar sequence
Representative Public ID C17E7.5 NCBI
Target Description C17E7.5 /REP_DB=WormBase Gene ID /WP=CE08265 /TR=O16388 /GB=AAC24277.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=nuclear hormone receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_071666(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_071666 NCBI Caenorhabditis elegans C17E7.5 (C17E7.5) mRNA, complete cds. 11/11 None
SNAP00000014081 ENSEMBL cdna:SNAP chromosome:CEL140:V:3866369:3868785:-1 11/11 None
GENEFINDER00000014104 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:3864840:3868785:-1 10/11 None
C17E7.5 ENSEMBL cdna:known chromosome:CEL140:V:3866369:3868818:-1 gene:C17E7.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:3866368-3868818(-) 100.0 100.0
Public Domain and Genome References
Gene Title nuclear hormone receptor
Gene Symbol nhr-157
Ensembl C17E7.5
Entrez Gene 182730 Entrez gene
SwissProt O16388 EMBL-EBI
WormBase CE08265 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3700 transcription factor activity inferred from electronic annotation QuickGO AmiGO
3707 steroid hormone receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC24277 Hypothetical protein C17E7.5 [Caenorhabditis elegans] ref|NP_504067.1| C17E7.5 [Caenorhabditis elegans] 0.0
blast AAC24277 Hypothetical protein C17E7.5 [Caenorhabditis elegans] ref|NP_504067.1| C17E7.5 [Caenorhabditis elegans] 1.0E-175
blast AAC24272 Hypothetical protein C17E7.6 [Caenorhabditis elegans] ref|NP_504068.1| C17E7.6 [Caenorhabditis elegans] 1.0E-101
blast AAC24272 Hypothetical protein C17E7.6 [Caenorhabditis elegans] ref|NP_504068.1| C17E7.6 [Caenorhabditis elegans] 3.0E-93
blast CAE56147 Hypothetical protein CBG23760 [Caenorhabditis briggsae] 3.0E-90
Protein Domains
Database ID Description E-Value
Pfam IPR000536 EMBL-EBI Ligand-binding domain of nuclear hormone receptor 3.4E-52
Pfam IPR001628 EMBL-EBI Zn-finger, C4-type steroid receptor 2.9E-9
Pfam IPR000536 EMBL-EBI Ligand-binding domain of nuclear hormone receptor 3.4E-52
Pfam IPR001628 EMBL-EBI Zn-finger, C4-type steroid receptor 2.9E-9
Pfam IPR000536 EMBL-EBI Ligand-binding domain of nuclear hormone receptor 2.1E-45
Sequence
Target Sequence 
>C. ELEGANS:190963_AT
gtcgcttgactttatgagctcactgaatttgaatattcaggataaaaaaatcttgcttaa
acactactgtgtaaaggcgtcgctgtttgccagcgcgatgagagcaatgaaggagcaaag
gaacactttgatgaccgtcgatggcaaggaaatttatccagatgcaattcttcggctaaa
acagatttcaccgcaatttctacagaggattcgaagtctgttagtgatgaagcttattga
attgaaaataactgatgaagagttcgcactggtcaatgctatatttttctgtaacgcagc
gctacctctatccgaagacggccagaaaacagtggtgactcagcaaaaagcctactcttc
agcactcctacagttttgcaacgttgaaagtagtcgaaatgggccgacaagattcacaaa
tctgctttcacttttgcacgtgatcaacaaaaactttgaagatgtgaaggcaatgaccat
gcttttcagaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTCGCTTGACTTTATGAGCTCACTG 347 475 573 Antisense
ACTACTGTGTAAAGGCGTCGCTGTT 126 101 635 Antisense
GCTGTTTGCCAGCGCGATGAGAGCA 23 297 654 Antisense
GGAACACTTTGATGACCGTCGATGG 559 527 692 Antisense
GATTTCACCGCAATTTCTACAGAGG 249 429 756 Antisense
GAAGAGTTCGCACTGGTCAATGCTA 399 339 829 Antisense
TTTTCTGTAACGCAGCGCTACCTCT 342 673 857 Antisense
GCTACCTCTATCCGAAGACGGCCAG 76 303 873 Antisense
AGCAAAAAGCCTACTCTTCAGCACT 152 77 914 Antisense
TCTTCAGCACTCCTACAGTTTTGCA 312 617 928 Antisense
AAGGCAATGACCATGCTTTTCAGAA 516 159 1039 Antisense
Sequence Source Affymetrix Proprietary Database