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[190950_at] Aminotransferases class-I

Description F28H6.3 /REP_DB=WormBase Gene ID /WP=CE18648 /TR=Q9XX97 /GB=CAA20930.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=Aminotransferases class-I
Cluster 6grp_total > 71      4grp_total > 57      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 90
1 2 3 4 range
A 39.4
(-3)
A 		57
(-1.7)
A 		118.4
(3)
P 		101.5
(1.7)
P 		79
B 86.9
(2.2)
P 		95.4
(3)
A 		60.6
(-0.1)
A 		28.3
(-3)
A 		67
C 54.2
(-1.9)
A 		84.4
(3)
A 		63.9
(-0.4)
A 		47.7
(-3)
A 		37
avr 60.2
(-2.7) 		78.9
(2.4) 		81
(3) 		59.2
(-3) 		22

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 104
1 2 3 4 5 6 range
A 85.1
(1.8)
P 		51.5
(-0.2)
P 		75.9
(1.2)
A 		106.6
(3)
P 		58.7
(0.2)
A 		2.8
(-3)
A 		104
B 55
(-3)
A 		74.2
(-0.4)
A 		57.1
(-2.7)
M 		98.5
(3)
P 		65.3
(-1.6)
M 		81.4
(0.6)
P 		44
C 32.7
(-3)
A 		93.2
(3)
P 		66.7
(0.4)
A 		51.1
(-1.2)
A 		52.7
(-1)
A 		44
(-1.9)
A 		61
avr 57.6
(-0.9) 		73
(1.3) 		66.6
(0.4) 		85.4
(3) 		58.9
(-0.7) 		42.7
(-3) 		43
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 25
1 2 3 4 range
A 14.4
(-2.4)
A 		12.4
(-3)
A 		30.9
(3)
P 		14.9
(-2.2)
P 		19
B 27.7
(3)
P 		23.6
(1.9)
A 		14.1
(-0.8)
A 		6
(-3)
A 		22
C 17.9
(0.6)
A 		24.3
(3)
A 		22.3
(2.3)
A 		8
(-3)
A 		16
avr 20
(1.9) 		20.1
(1.9) 		22.4
(3) 		9.6
(-3) 		13

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 30
1 2 3 4 5 6 range
A 15.7
(0.4)
P 		18.3
(1)
P 		16.5
(0.6)
A 		27
(3)
P 		17.7
(0.9)
A 		0.7
(-3)
A 		26
B 19.1
(-1.1)
A 		24.7
(0.9)
A 		13.9
(-3)
M 		26.1
(1.4)
P 		26.5
(1.6)
M 		30.4
(3)
P 		17
C 12.1
(-2.4)
A 		28.5
(3)
P 		17
(-0.8)
A 		10.3
(-3)
A 		17
(-0.8)
A 		14.7
(-1.5)
A 		18
avr 15.6
(-2.8) 		23.8
(3) 		15.8
(-2.6) 		21.1
(1.1) 		20.4
(0.6) 		15.3
(-3) 		9
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190950_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17380
Sequence Type Exemplar sequence
Representative Public ID F28H6.3 NCBI
Target Description F28H6.3 /REP_DB=WormBase Gene ID /WP=CE18648 /TR=Q9XX97 /GB=CAA20930.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=Aminotransferases class-I
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077954(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077954 NCBI Caenorhabditis elegans F28H6.3 (F28H6.3) mRNA, complete cds. 11/11 None
SNAP00000032401 ENSEMBL cdna:SNAP chromosome:CEL140:X:14138020:14139990:-1 11/11 None
GENEFINDER00000032405 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:14138020:14139990:-1 11/11 None
F28H6.3 ENSEMBL cdna:known chromosome:CEL140:X:14138020:14139990:-1 gene:F28H6.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:14138019-14139990(-) 100.0 100.0
Public Domain and Genome References
Gene Title Aminotransferases class-I
Ensembl F28H6.3
Entrez Gene 185086 Entrez gene
SwissProt Q9XX97 EMBL-EBI
WormBase CE18648 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1601385_AT similar to Kynurenine--oxoglutarate transaminase I (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) cfa
CANINE:1586840_AT similar to Kynurenine--oxoglutarate transaminase I (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) cfa
CANINE_2:CFA.12131.1.A1_AT similar to Kynurenine--oxoglutarate transaminase I (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) cfa
CANINE_2:CFA.17433.1.S1_S_AT similar to Kynurenine--oxoglutarate transaminase I (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) cfa
CANINE_2:CFAAFFX.30657.1.S1_AT similar to Kynurenine--oxoglutarate transaminase I (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) cfa
CANINE_2:CFAAFFX.30657.1.S1_S_AT similar to Kynurenine--oxoglutarate transaminase I (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) cfa
CANINE_2:CFAAFFX.30658.1.S1_AT similar to Kynurenine--oxoglutarate transaminase I (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) cfa
CHICKEN:GGA.11673.1.S1_S_AT similar to Kynurenine--oxoglutarate transaminase I (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) gga
CHICKEN:GGAAFFX.26258.1.S1_AT similar to Kynurenine--oxoglutarate transaminase I (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) gga
CHICKEN:GGAAFFX.2848.1.S1_AT similar to Kynurenine--oxoglutarate transaminase I (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) gga
CHICKEN:GGAAFFX.2848.1.S1_S_AT similar to Kynurenine--oxoglutarate transaminase I (Kynurenine aminotransferase I) (KATI) (Glutamine--phenylpyruvate transaminase) (Glutamine transaminase K) (GTK) (Cysteine-S-conjugate beta-lyase) gga
HG-U133_PLUS_2:206037_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
HG-U133A:206037_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
HG-FOCUS:206037_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
HG-U133A_2:206037_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
HG-U95AV2:36691_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
HU35KSUBA:HUM_ALU_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
HU35KSUBB:HUM_ALU_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
HU35KSUBC:HUM_ALU_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
HU35KSUBD:HUM_ALU_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
HUGENEFL:HUM_ALU_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
HC-G110:HUM_ALU_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
HU35KSUBC:RC_AA609620_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
HUGENEFL:X82224_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
U133_X3P:G11038631_3P_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
U133_X3P:HS2.382311.1.S1_3P_X_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
U133_X3P:1570651_3P_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
HG-U133_PLUS_2:1570651_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
HG-U95AV2:36330_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
HG-U133_PLUS_2:1570650_AT cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) hs
MOUSE430_2:1438348_X_AT cysteine conjugate-beta lyase 1 mm
MOE430B:1438348_X_AT cysteine conjugate-beta lyase 1 mm
MG-U74BV2:110296_AT cysteine conjugate-beta lyase 1 mm
MOE430B:1428151_X_AT cysteine conjugate-beta lyase 1 mm
MOUSE430_2:1428151_X_AT cysteine conjugate-beta lyase 1 mm
MOE430B:1452678_A_AT cysteine conjugate-beta lyase 1 mm
MOUSE430_2:1452678_A_AT cysteine conjugate-beta lyase 1 mm
MOE430B:1446302_AT Cysteine conjugate-beta lyase 1, mRNA (cDNA clone MGC:62427 IMAGE:5687475) mm
MOUSE430_2:1446302_AT Cysteine conjugate-beta lyase 1, mRNA (cDNA clone MGC:62427 IMAGE:5687475) mm
MG-U74BV2:165088_R_AT Cysteine conjugate-beta lyase 1, mRNA (cDNA clone MGC:62427 IMAGE:5687475) mm
MU19KSUBA:TC25402_AT Cysteine conjugate-beta lyase 1, mRNA (cDNA clone MGC:62427 IMAGE:5687475) mm
MU19KSUBB:TC33223_AT Cysteine conjugate-beta lyase 1, mRNA (cDNA clone MGC:62427 IMAGE:5687475) mm
MU19KSUBB:TC33223_G_AT Cysteine conjugate-beta lyase 1, mRNA (cDNA clone MGC:62427 IMAGE:5687475) mm
RG-U34A:S61960_S_AT cysteine conjugate-beta lyase (predicted) rn
RG-U34C:RC_AI171692_S_AT cysteine conjugate-beta lyase (predicted) rn
RAE230A:1373667_AT cysteine conjugate-beta lyase (predicted) rn
RAT230_2:1373667_AT cysteine conjugate-beta lyase (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
9058 biosynthesis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8483 transaminase activity inferred from electronic annotation QuickGO AmiGO
16847 1-aminocyclopropane-1-carboxylate synthase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA20930 Hypothetical protein F28H6.3 [Caenorhabditis elegans] ref|NP_510355.1| F28H6.3 [Caenorhabditis elegans] 0.0
blast CAE63314 Hypothetical protein CBG07704 [Caenorhabditis briggsae] 1.0E-160
blast CAI46593 Hypothetical protein R03A10.4b [Caenorhabditis elegans] ref|NP_001024823.1| R03A10.4b [Caenorhabditis elegans] 1.0E-159
Protein Families
Method ID Description E-Value
ec 1A11_CUCMA (P23599) 1-aminocyclopropane-1-carboxylate synthase CMW33 (EC 4.4.1.14) (ACC synthase) (S-adenosyl-L-methionine methylthioadenosine-lyase) 1.0E-121
ec 1A11_CUCMA (P23599) 1-aminocyclopropane-1-carboxylate synthase CMW33 (EC 4.4.1.14) (ACC synthase) (S-adenosyl-L-methionine methylthioadenosine-lyase) 1.0E-117
Protein Domains
Database ID Description E-Value
Pfam IPR004839 EMBL-EBI Aminotransferase, class I and II 1.6E-20
Pfam IPR004839 EMBL-EBI Aminotransferase, class I and II 1.7E-17
Sequence
Target Sequence 
>C. ELEGANS:190950_AT
cgatttgcaagccttcctggaatgtacgaacgaacaatttcaattggaagcgccggaaaa
gcgttatctgtaaccggctggaaactcggatgggcaatcggaccacaacatctcctctcc
ccgttgaaaacaatttctcaaaattgtgtttacacgtgtccgactcctattcaattggca
attgcacgtgcctttcaacaggattggcctaaattcatggagaatccaaaccagtcgtat
ttggcaaccggcttgcccaaagaagttatgcagaaaaggaagattttggcaaacatgctg
gaaaaagccaatttccaaacaattcttccagaggctggatttttcatgctcgcagagtgc
aagctgccaatgaaatctttcagtttctctcccattgtcgggaaagatccactggatgtt
cagtattcaaagtggctgtgtcgcgagaagaaacttgccgtgattcccttcagtattttt
ttctcatctaaagatcagaagcatctcagtggaagatttgttcgactctgttttttcaag
aaagacacaactcttcaggctgca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CGATTTGCAAGCCTTCCTGGAATGT 633 247 697 Antisense
ATGGGCAATCGGACCACAACATCTC 221 51 786 Antisense
ATTGTGTTTACACGTGTCCGACTCC 402 3 839 Antisense
GTGTCCGACTCCTATTCAATTGGCA 522 487 852 Antisense
ATTGCACGTGCCTTTCAACAGGATT 629 5 877 Antisense
CAGTCGTATTTGGCAACCGGCTTGC 666 205 928 Antisense
GGATTTTTCATGCTCGCAGAGTGCA 30 511 1033 Antisense
TCAGTTTCTCTCCCATTGTCGGGAA 335 623 1076 Antisense
GAAGAAACTTGCCGTGATTCCCTTC 36 341 1143 Antisense
GATTTGTTCGACTCTGTTTTTTCAA 613 427 1211 Antisense
GAAAGACACAACTCTTCAGGCTGCA 384 359 1236 Antisense
Sequence Source Affymetrix Proprietary Database