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[190933_at] serine/threonine kinase

Description VZC374L.1 /REP_DB=WormBase Gene ID /WP=CE16527 /TR=O01706 /GB=CAB08354.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_total > 30      4grp_total > 07      6grp_total_sub > Hat      6grp_rule_based > S3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 62
1 2 3 4 range
A 57.6
(-1.2)
P 		43.3
(-3)
A 		55.3
(-1.5)
A 		91.7
(3)
A 		48
B 73.9
(2)
A 		59.8
(0.3)
A 		82.2
(3)
A 		33.1
(-3)
A 		49
C 89.4
(1.8)
P 		66.7
(-3)
P 		73.2
(-1.6)
A 		94.8
(3)
A 		28
avr 73.6
(3) 		56.6
(-3) 		70.2
(1.8) 		73.2
(2.9) 		17

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 89
1 2 3 4 5 6 range
A 53.6
(-2.4)
A 		99.7
(1.7)
P 		114.1
(3)
P 		77.7
(-0.3)
A 		47.1
(-3)
A 		62.4
(-1.6)
A 		67
B 80.8
(1)
A 		77.4
(0.7)
M 		103.1
(3)
P 		96.7
(2.4)
P 		62.9
(-0.6)
A 		36.4
(-3)
A 		67
C 59.3
(-0.3)
A 		100.1
(3)
A 		62.4
(-0)
A 		77.9
(1.2)
A 		25.5
(-3)
A 		43.8
(-1.5)
A 		75
avr 64.6
(-0.6) 		92.4
(2.9) 		93.2
(3) 		84.1
(1.9) 		45.2
(-3) 		47.5
(-2.7) 		48
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 23
1 2 3 4 range
A 21
(3)
P 		9.4
(-3)
A 		14.4
(-0.4)
A 		13.4
(-0.9)
A 		12
B 23.6
(3)
A 		14.8
(-0.2)
A 		19
(1.3)
A 		7.1
(-3)
A 		17
C 29.6
(3)
P 		19.2
(-1.6)
P 		25.5
(1.2)
A 		16
(-3)
A 		14
avr 24.7
(3) 		14.5
(-1.9) 		19.6
(0.6) 		12.2
(-3) 		13

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 27
1 2 3 4 5 6 range
A 9.9
(-3)
A 		35.5
(3)
P 		24.8
(0.5)
P 		19.7
(-0.7)
A 		14.2
(-2)
A 		15.2
(-1.8)
A 		26
B 28.1
(3)
A 		25.8
(2)
M 		25
(1.7)
P 		25.6
(2)
P 		25.5
(1.9)
A 		13.6
(-3)
A 		15
C 22
(0.7)
A 		30.6
(3)
A 		15.9
(-0.9)
A 		15.7
(-1)
A 		8.2
(-3)
A 		14.7
(-1.3)
A 		22
avr 20
(-1) 		30.6
(3) 		21.9
(-0.2) 		20.3
(-0.8) 		16
(-2.4) 		14.5
(-3) 		16
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190933_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16353
Sequence Type Exemplar sequence
Representative Public ID VZC374L.1 NCBI
Target Description VZC374L.1 /REP_DB=WormBase Gene ID /WP=CE16527 /TR=O01706 /GB=CAB08354.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077282(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077282 NCBI Caenorhabditis elegans VZC374L.1 (VZC374L.1) mRNA, complete cds. 11/11 None
SNAP00000025103 ENSEMBL cdna:SNAP chromosome:CEL140:X:10031082:10032923:1 10/11 None
GENEFINDER00000025105 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:10031082:10032923:1 11/11 None
VZC374L.1 ENSEMBL cdna:known chromosome:CEL140:X:10031082:10032923:1 gene:VZC374L.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:10031081-10032923(+) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl VZC374L.1
Entrez Gene 189074 Entrez gene
SwissProt O01706 EMBL-EBI
WormBase CE16527 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB08354 Hypothetical protein VZC374L.1 [Caenorhabditis elegans] ref|NP_509683.1| VZC374L.1 [Caenorhabditis elegans] 0.0
blast CAA88264 Hypothetical protein F42G10.2 [Caenorhabditis elegans] emb|CAB08355.1| Hypothetical protein F42G10.2 [Caenorhabditis elegans] ref|NP_509682.1| MKK (MAP Kinase Kinase) homolog family member (mkk-4) [Caenorhabditis elegans] sp|Q20347|YR62_CAEEL Putative serine/threonine-protein kinase F42G10.2 1.0E-129
blast CAE58750 Hypothetical protein CBG01940 [Caenorhabditis briggsae] 1.0E-123
Protein Families
Method ID Description E-Value
hanks 1.1.18 AGC group; AGC I Cyclic nucleotide regulated protein kinase (PKA & PKG); DG2 6.0E-21
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 4.2E-46
Pfam IPR000719 EMBL-EBI Protein kinase 2.8E-44
Sequence
Target Sequence 
>C. ELEGANS:190933_AT
ttgtagacgctttggattacctcaaaagaaaactcaacagaattcatcgcgatgtgaaac
catcaaacattctgatcaatgcagctggtgatgtaaaactttgcgattttggaatatgcg
gagatcttgttggatcctatgcaataactgttgaagctggctgtgttcaatatctcgcgc
cggaacgaatcgaaaatatggacaagtatgatataagatctgacgtttggtcgttaggaa
ttaccttgtacgaaatcgcaactggagtgtatccttacagaggttggagtaatcaaatgg
aacatattgaaattgttgtaaacggagattctccaatacttctacaaaatatgcacaacc
tgcactatacggatccactttgccgattcataaacacctgtttgagaaaaaataaggatg
atagacccaaatatgttaacttgaaaacattctccttctacaaaatgtacgcagtcggag
gtcctgatattgaagaagcgaagaggattcttgggcttgaagcc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTGTAGACGCTTTGGATTACCTCAA 6 709 530 Antisense
AAACTCAACAGAATTCATCGCGATG 227 127 559 Antisense
GCGGAGATCTTGTTGGATCCTATGC 574 293 647 Antisense
GCTGGCTGTGTTCAATATCTCGCGC 223 295 685 Antisense
ATATCTCGCGCCGGAACGAATCGAA 571 17 699 Antisense
ATCGCAACTGGAGTGTATCCTTACA 180 37 784 Antisense
ACGGAGATTCTCCAATACTTCTACA 287 95 851 Antisense
TGCACAACCTGCACTATACGGATCC 247 577 881 Antisense
GGATCCACTTTGCCGATTCATAAAC 507 513 900 Antisense
AATGTACGCAGTCGGAGGTCCTGAT 549 161 993 Antisense
GAAGAGGATTCTTGGGCTTGAAGCC 156 339 1029 Antisense
Sequence Source Affymetrix Proprietary Database