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[190931_s_at] oxysterol-binding protein

Description F14H8.1 /REP_DB=WormBase Gene ID /WP=CE23653 /TR=Q93485 /GB=CAB02934.2 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=oxysterol-binding protein
Cluster 6grp_highest_10_10 > 29      6grp_high1_10_10 > 81      4grp_highest_8_8 > 22      4grp_high_8_8 > 06      6grp_highest_nonorm > 55      6grp_total > 83      4grp_total > 09      6grp_highest_sub > 04_05      6grp_cgc > 86      6grp_high1_sub > 04      6grp_cgc_sub > 04      6grp_total_sub > Hat      6grp_rule_based > S4      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 3262
1 2 3 4 range
A 981.8
(-3)
P
1114.1
(-2.8)
P
1174.8
(-2.6)
P
4243.3
(3)
P
3262
B 1080.4
(-3)
P
1131.3
(-2.9)
P
1214.3
(-2.7)
P
3845.3
(3)
P
2765
C 993.6
(-3)
P
1123.6
(-2.7)
P
1220.5
(-2.6)
P
4062.3
(3)
P
3069
avr 1018.6
(-3)
1123
(-2.8)
1203.2
(-2.6)
4050.3
(3)
3032

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1388
1 2 3 4 5 6 range
A 976.3
(-3)
P
1102.9
(-2.3)
P
1491.3
(-0.2)
P
2076.5
(3)
P
1952.9
(2.3)
P
1115.2
(-2.2)
P
1100
B 966.5
(-3)
P
1206.4
(-1.9)
P
1304.2
(-1.4)
P
1851.5
(1.2)
P
2219.2
(3)
P
1213.5
(-1.8)
P
1253
C 915.4
(-3)
P
1236
(-1.6)
P
1314.9
(-1.3)
P
2303.3
(3)
P
1747.6
(0.6)
P
1152
(-2)
P
1388
avr 952.7
(-3)
1181.8
(-1.8)
1370.1
(-0.8)
2077.1
(3)
1973.2
(2.4)
1160.2
(-1.9)
1124
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 578
1 2 3 4 range
A 357.5
(-1.2)
P
241.8
(-3)
P
307.1
(-2)
P
621.1
(3)
P
379
B 344.5
(-2.3)
P
279.4
(-3)
P
281.4
(-3)
P
819.4
(3)
P
540
C 328.9
(-2.9)
P
323
(-3)
P
425.4
(-1.3)
P
685
(3)
P
362
avr 343.6
(-2.1)
281.4
(-3)
338
(-2.2)
708.5
(3)
427

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 722
1 2 3 4 5 6 range
A 180
(-3)
P
392.2
(0.1)
P
324.8
(-0.9)
P
526.7
(2.1)
P
589.3
(3)
P
271.5
(-1.7)
P
409
B 336.3
(-2.8)
P
401.6
(-2.1)
P
316.7
(-3)
P
490.4
(-1.2)
P
901.6
(3)
P
452.5
(-1.6)
P
585
C 339.3
(-2.9)
P
377.2
(-1.9)
P
334.7
(-3)
P
463.2
(0.3)
P
565.5
(3)
P
385.6
(-1.7)
P
231
avr 285.2
(-3)
390.3
(-1.4)
325.4
(-2.4)
493.4
(0.1)
685.5
(3)
369.9
(-1.7)
400
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190931_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.12664
Sequence Type Exemplar sequence
Representative Public ID F14H8.1 NCBI
Target Description F14H8.1 /REP_DB=WormBase Gene ID /WP=CE23653 /TR=Q93485 /GB=CAB02934.2 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=oxysterol-binding protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074294(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_074294 NCBI Caenorhabditis elegans Oxysterol Binding protein (OSBP) Related family member (obr-2) (obr-2) mRNA, complete cds. 11/11 None
SNAP00000006129 ENSEMBL cdna:SNAP chromosome:CEL140:V:15014559:15016778:-1 11/11 None
F14H8.1 ENSEMBL cdna:known chromosome:CEL140:V:15014479:15016808:-1 gene:F14H8.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000006139 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:15014558-15016808(-) 100.0 100.0
Public Domain and Genome References
Gene Title oxysterol-binding protein
Gene Symbol obr-2
Ensembl F14H8.1
Entrez Gene 180003 Entrez gene
SwissProt Q93485 EMBL-EBI
WormBase CE35859 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1640415_AT dm
DROSGENOME1:152415_AT dm
CHICKEN:GGA.7435.1.S1_A_AT similar to oxysterol-binding protein-like 1A isoform B; oxysterol-binding protein-related protein 1; oxysterol-binding protein-like 1B; OSBP-related protein 1 gga
CHICKEN:GGA.7435.1.S1_AT similar to oxysterol-binding protein-like 1A isoform B; oxysterol-binding protein-related protein 1; oxysterol-binding protein-like 1B; OSBP-related protein 1 gga
CHICKEN:GGA.7435.3.S1_A_AT similar to oxysterol-binding protein-like 1A isoform B; oxysterol-binding protein-related protein 1; oxysterol-binding protein-like 1B; OSBP-related protein 1 gga
CHICKEN:GGAAFFX.9583.1.S1_AT similar to oxysterol-binding protein-like 1A isoform B; oxysterol-binding protein-related protein 1; oxysterol-binding protein-like 1B; OSBP-related protein 1 gga
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8202 steroid metabolism inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB02934 Hypothetical protein F14H8.1 [Caenorhabditis elegans] ref|NP_506695.2| Oxysterol Binding protein (OSBP) Related family member (obr-2) [Caenorhabditis elegans] 0.0
blast CAE66333 Hypothetical protein CBG11584 [Caenorhabditis briggsae] 0.0
blast CAE66333 Hypothetical protein CBG11584 [Caenorhabditis briggsae] 1.0E-163
blast XP_685655 PREDICTED: similar to Oxysterol binding protein-like 1A [Danio rerio] ref|XP_686942.1| PREDICTED: similar to Oxysterol binding protein-like 1A [Danio rerio] 1.0E-69
blast XP_685655 PREDICTED: similar to Oxysterol binding protein-like 1A [Danio rerio] ref|XP_686942.1| PREDICTED: similar to Oxysterol binding protein-like 1A [Danio rerio] 8.0E-52
Protein Domains
Database ID Description E-Value
Pfam IPR000648 EMBL-EBI Oxysterol-binding protein 4.3E-65
Pfam IPR000648 EMBL-EBI Oxysterol-binding protein 6.0E-40
Pfam IPR000648 EMBL-EBI Oxysterol-binding protein 9.2E-7
Sequence
Target Sequence
>C. ELEGANS:190931_S_AT
tacgacgcagtgttctcattcgacaacaaaggatactacaaccataagggaggtgatgta
cacgtggaaggacacattttcgaaggaaagaataagatcaaagcattgtacggaaattgg
acacttttcctggcatcctgtgataatgaagacttcaaacatcatcggaaggagtatctt
cgaatgtttaatgaaacagtttcggaaaaggatcagggtcctgtggtaccgggatccaag
attctttgggtttcgaatcagattccgaagctcttcgatgatcagttccactttaccaac
ttcacactttctctcaatgaaatgtatcctggaatgagtgacactgttgctccaactgat
agtcgtcgtcgtaaggatatgaaagcattggaagatgggaaaaatgatgaagctgaagag
tttaaacataagtatgaagaggagcaacgggagagaagaaccactaagactggtgatgtt
cccatgtggtttgccaaaaacgacgaaggtcactgggcgtacaagggtggctactgggat
cgtgactactccaattgtctggaacttttcgagtctctgga


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
TACGACGCAGTGTTCTCATTCGACA 98 649 799 Antisense
AAATTGGACACTTTTCCTGGCATCC 299 115 912 Antisense
GTCCTGTGGTACCGGGATCCAAGAT 693 475 1016 Antisense
GAAGCTCTTCGATGATCAGTTCCAC 188 343 1065 Antisense
TGATCAGTTCCACTTTACCAACTTC 565 559 1077 Antisense
AATGAGTGACACTGTTGCTCCAACT 616 163 1131 Antisense
CTCCAACTGATAGTCGTCGTCGTAA 115 237 1148 Antisense
CGAAGGTCACTGGGCGTACAAGGGT 650 237 1302 Antisense
ACAAGGGTGGCTACTGGGATCGTGA 448 113 1319 Antisense
GGGATCGTGACTACTCCAATTGTCT 517 495 1334 Antisense
GTCTGGAACTTTTCGAGTCTCTGGA 273 471 1355 Antisense
Sequence Source Affymetrix Proprietary Database