[Home] | [Total List]

[190903_at] protein-tyrosine kinase

Description F53G12.6 /REP_DB=WormBase Gene ID /WP=CE11016 /TR=O01798 /GB=AAB54162.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=protein-tyrosine kinase
Cluster 6grp_total > 88      4grp_total > 36      6grp_cgc > 59      6grp_cgc_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 6
1 2 3 4 range
A 4.3
(-3)
A 		8.2
(3)
A 		7
(1.2)
A 		4.8
(-2.2)
A 		4
B 5
(0.3)
A 		7.1
(2.8)
A 		2.1
(-3)
A 		7.3
(3)
A 		5
C 7.7
(3)
A 		6.5
(1.1)
A 		3.9
(-3)
A 		5.9
(0.2)
A 		4
avr 5.7
(-0.2) 		7.3
(3) 		4.3
(-3) 		6
(0.4) 		3

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 56
1 2 3 4 5 6 range
A 23
(-0.7)
A 		3.5
(-2.8)
A 		5.8
(-2.6)
A 		1.9
(-3)
A 		22.8
(-0.7)
A 		57.2
(3)
A 		55
B 1.4
(-3)
A 		5.3
(-2.3)
A 		3.4
(-2.6)
A 		2
(-2.9)
A 		16.5
(-0.3)
A 		35.3
(3)
A 		34
C 3.3
(-2.8)
A 		2.2
(-3)
A 		3.9
(-2.7)
A 		6.7
(-2.1)
A 		33.3
(3)
A 		31
(2.6)
A 		31
avr 9.2
(-2.1) 		3.7
(-3) 		4.4
(-2.9) 		3.5
(-3) 		24.2
(0.3) 		41.2
(3) 		38
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2
1 2 3 4 range
A 1.6
(1.9)
A 		1.8
(3)
A 		1.8
(3)
A 		0.7
(-3)
A 		1
B 1.6
(2.1)
A 		1.8
(3)
A 		0.5
(-3)
A 		1.6
(2.1)
A 		1
C 2.6
(3)
A 		1.9
(0.4)
A 		1.4
(-1.5)
A 		1
(-3)
A 		2
avr 1.9
(3) 		1.8
(2.3) 		1.2
(-2.3) 		1.1
(-3) 		1

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 13
1 2 3 4 5 6 range
A 4.2
(-1.3)
A 		1.2
(-2.7)
A 		1.3
(-2.6)
A 		0.5
(-3)
A 		6.9
(-0.1)
A 		13.9
(3)
A 		13
B 0.5
(-3)
A 		1.8
(-2.4)
A 		0.8
(-2.9)
A 		0.5
(-3)
A 		6.7
(-0)
A 		13.1
(3)
A 		13
C 1.2
(-2.7)
A 		0.7
(-3)
A 		1
(-2.8)
A 		1.3
(-2.6)
A 		10.8
(3)
A 		10.4
(2.8)
A 		10
avr 2
(-2.4) 		1.2
(-2.8) 		1
(-2.9) 		0.8
(-3) 		8.1
(0.7) 		12.5
(3) 		12
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190903_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2584
Sequence Type Exemplar sequence
Representative Public ID F53G12.6 NCBI
Target Description F53G12.6 /REP_DB=WormBase Gene ID /WP=CE11016 /TR=O01798 /GB=AAB54162.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=protein-tyrosine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_058279(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_058279 NCBI Caenorhabditis elegans defective SPErmatogenesis family member (spe-8) (spe-8) mRNA, complete cds. 11/11 None
SNAP00000020923 ENSEMBL cdna:SNAP chromosome:CEL140:I:118109:120870:1 11/11 None
GENEFINDER00000020938 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:118109:120870:1 11/11 None
F53G12.6 ENSEMBL cdna:known chromosome:CEL140:I:118109:120870:1 gene:F53G12.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:118386-120870(+) 97.57 100.0
Public Domain and Genome References
Gene Title protein-tyrosine kinase
Gene Symbol spe-8
Ensembl F53G12.6
Entrez Gene 171606 Entrez gene
SwissProt O01798 EMBL-EBI
WormBase CE29331 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB54162 Defective spermatogenesis protein 8 [Caenorhabditis elegans] ref|NP_490680.1| defective SPErmatogenesis family member (spe-8) [Caenorhabditis elegans] 0.0
blast CAE61280 Hypothetical protein CBG05099 [Caenorhabditis briggsae] 0.0
blast CAB03003 Hypothetical protein F26E4.5 [Caenorhabditis elegans] ref|NP_492594.2| F26E4.5 [Caenorhabditis elegans] 5.0E-71
Protein Families
Method ID Description E-Value
hanks 1.8.4 AGC group; AGC VIII Flowering plant PVPK1 homologs; ATPK5 1.0E-65
Protein Domains
Database ID Description E-Value
Pfam IPR000980 EMBL-EBI SH2 motif 1.1E-17
Pfam IPR000719 EMBL-EBI Protein kinase 7.3E-63
Pfam IPR000719 EMBL-EBI Protein kinase 7.0E-27
Pfam IPR000719 EMBL-EBI Protein kinase 4.2E-18
Sequence
Target Sequence 
>C. ELEGANS:190903_AT
gacgctctactctccaaggaagaaaaagtgtcagctgaggacaagattctctaccttttc
cacgccgcctgcggtattgattatttgcacggaaagcaggttattcacagggatattgcg
gcgagaaattgtttgttgaattccaaaaagatcctgaaaatctccgactttggattgtcg
gtcaaaggagttgctataaaggagcgaaagggaggatgtctgccggtcaagtacatggct
ccggagacattgaagaaggggttgtacagtactgcctctgatatttatagctacggcgct
ctaatgtacgaagtctacacggacggaaagacgccattcgaaacgtgcgggctacgtgga
aatgagctccgaaaagcgatcatcgggaagagaatcagcttggccgttgaggtagagcta
ccagtgttcattgccaacattttcgagcaaagcaggcagtacgagaccgaagatcgcata
agctccaagcaaattattcagatttttaaggaggaagtcggattccatgaaattgagaca
agtgggatactgcataagcttgtcaattctcttccgag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GACGCTCTACTCTCCAAGGAAGAAA 107 381 874 Antisense
AGGACAAGATTCTCTACCTTTTCCA 610 53 911 Antisense
TCCACGCCGCCTGCGGTATTGATTA 283 587 932 Antisense
GAAAGGGAGGATGTCTGCCGGTCAA 288 359 1079 Antisense
TCTGCCGGTCAAGTACATGGCTCCG 490 609 1092 Antisense
AGGGGTTGTACAGTACTGCCTCTGA 511 57 1130 Antisense
ATAGCTACGGCGCTCTAATGTACGA 297 21 1160 Antisense
GACGCCATTCGAAACGTGCGGGCTA 321 381 1203 Antisense
GAGAATCAGCTTGGCCGTTGAGGTA 366 391 1263 Antisense
GTAGAGCTACCAGTGTTCATTGCCA 263 457 1285 Antisense
ATAAGCTTGTCAATTCTCTTCCGAG 605 25 1427 Antisense
Sequence Source Affymetrix Proprietary Database