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[190881_s_at] serine/threonine kinase

Description Y106G6A.1 /REP_DB=WormBase Gene ID /WP=CE19294 /TR=Q9XWQ5 /GB=CAA21594.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_highest_10_10 > 38      6grp_high1_10_10 > 72      4grp_highest_8_8 > 39      4grp_high_8_8 > 04      6grp_highest_nonorm > 62      6grp_total > 70      4grp_total > 05      6grp_highest_sub > 04      6grp_high1_sub > 04      6grp_total_sub > Hat      6grp_rule_based > S4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 520
1 2 3 4 range
A 462.2
(1.9)
P 		298.3
(-1.4)
P 		215.7
(-3)
P 		517.1
(3)
P 		301
B 369.1
(-1.3)
P 		273.3
(-2.6)
P 		243.6
(-3)
P 		695.1
(3)
P 		452
C 410.1
(-1.2)
P 		265
(-3)
P 		288.5
(-2.7)
P 		735.9
(3)
P 		471
avr 413.8
(-0.5) 		278.9
(-2.6) 		249.3
(-3) 		649.4
(3) 		400

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 373
1 2 3 4 5 6 range
A 327.3
(-2.6)
P 		301.3
(-3)
P 		604.4
(1.9)
P 		674.1
(3)
P 		451.2
(-0.6)
P 		465.9
(-0.4)
P 		373
B 497
(-1)
P 		489.1
(-1.6)
P 		510.4
(0.1)
P 		547.8
(3)
P 		515.2
(0.5)
P 		470.9
(-3)
P 		77
C 442.4
(-3)
P 		453.5
(-2.7)
P 		459.2
(-2.5)
P 		673.9
(3)
P 		440.9
(-3)
P 		474.9
(-2.1)
P 		233
avr 422.2
(-2.8) 		414.6
(-3) 		524.7
(0) 		631.9
(3) 		469.1
(-1.5) 		470.6
(-1.5) 		217
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 112
1 2 3 4 range
A 168.3
(3)
P 		64.8
(-2.5)
P 		56.4
(-3)
P 		75.7
(-2)
P 		112
B 117.7
(1)
P 		67.5
(-2.3)
P 		56.5
(-3)
P 		148.1
(3)
P 		92
C 135.8
(3)
P 		76.2
(-3)
P 		100.6
(-0.5)
P 		124.1
(1.8)
P 		60
avr 140.6
(3) 		69.5
(-3) 		71.2
(-2.9) 		116
(0.9) 		71

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 149
1 2 3 4 5 6 range
A 60.3
(-3)
P 		107.2
(-0.5)
P 		131.6
(0.9)
P 		171
(3)
P 		136.1
(1.1)
P 		113.4
(-0.1)
P 		111
B 172.9
(0.4)
P 		162.8
(-0.3)
P 		123.9
(-3)
P 		145.1
(-1.5)
P 		209.3
(3)
P 		175.6
(0.6)
P 		85
C 164
(3)
P 		138.4
(-0.3)
P 		116.9
(-3)
P 		135.5
(-0.6)
P 		142.7
(0.3)
P 		159
(2.4)
P 		47
avr 132.4
(-1.7) 		136.1
(-1.1) 		124.1
(-3) 		150.5
(1.1) 		162.7
(3) 		149.3
(0.9) 		39
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190881_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2528
Sequence Type Exemplar sequence
Representative Public ID Y106G6A.1 NCBI
Target Description Y106G6A.1 /REP_DB=WormBase Gene ID /WP=CE19294 /TR=Q9XWQ5 /GB=CAA21594.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060228(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060228 NCBI Caenorhabditis elegans Y106G6A.1 (Y106G6A.1) mRNA, complete cds. 11/11 None
SNAP00000021908 ENSEMBL cdna:SNAP chromosome:CEL140:I:9944378:9946274:-1 11/11 None
GENEFINDER00000021910 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:9944378:9946274:-1 11/11 None
Y106G6A.1 ENSEMBL cdna:known chromosome:CEL140:I:9944264:9946421:-1 gene:Y106G6A.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:9944308-9946205(-) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl Y106G6A.1
Entrez Gene 172850 Entrez gene
SwissProt Q9XWQ5 EMBL-EBI
WormBase CE19294 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA21594 Hypothetical protein Y106G6A.1 [Caenorhabditis elegans] ref|NP_492629.1| Y106G6A.1 [Caenorhabditis elegans] 0.0
blast CAE60255 Hypothetical protein CBG03830 [Caenorhabditis briggsae] 1.0E-158
blast XP_476419 putative MAP3K protein kinase(Mitogen-activated protein kinase) [Oryza sativa (japonica cultivar-group)] dbj|BAD30278.1| putative MAP3K protein kinase(Mitogen-activated protein kinase) [Oryza sativa (japonica cultivar-group)] dbj|BAC79731.1| putative MAP3K protein kinase(Mitogen-activated protein kinase) [Oryza sativa (japonica cultivar-group)] 2.0E-28
Protein Families
Method ID Description E-Value
hanks 2.2.11 CaMK Group; CaMK II KIN1/SNF1/Nim1; YKL453 2.0E-23
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 2.5E-56
Sequence
Target Sequence 
>C. ELEGANS:190881_S_AT
agaactggacctttgcatcatgagctggttaaggcttacgcaaaacagattcttgaagga
ctagagttcttgcactcgaaaaacataattcatcaagatttaaagccagcaaacctttta
ttaaaaaatacgcatcgcgaaaggctcattaaaattgcggatttcggatcgagcaggttt
tcctcactgaagcgggaacgtgaaggacaacaaggaagaactccaaaatacactgatcca
ggtgtatcgttaggaagacatgtttctggaaggcgatctgatatttggagtcttggagtt
attataattgaaatgtatacaggagtatatccatggtctatagatggtgaacatccgatt
actgtaccaagaattctcgatgaaaatccaccgaattttacgacaagcgaaaaaattgac
gaaaatctgatcaaaatggcaaaacttatgcttcaatcagtcgccaaaagaccatatgca
tctactcttctagaacttccaattcttc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGAACTGGACCTTTGCATCATGAGC 657 73 742 Antisense
GAAGGACTAGAGTTCTTGCACTCGA 616 333 796 Antisense
ATACGCATCGCGAAAGGCTCATTAA 318 23 869 Antisense
TCGAGCAGGTTTTCCTCACTGAAGC 542 601 910 Antisense
GAACTCCAAAATACACTGATCCAGG 83 347 959 Antisense
GACATGTTTCTGGAAGGCGATCTGA 600 369 998 Antisense
GGCGATCTGATATTTGGAGTCTTGG 638 541 1013 Antisense
TCCACCGAATTTTACGACAAGCGAA 370 587 1128 Antisense
CTTATGCTTCAATCAGTCGCCAAAA 185 221 1186 Antisense
AGACCATATGCATCTACTCTTCTAG 225 71 1210 Antisense
ACTCTTCTAGAACTTCCAATTCTTC 538 99 1225 Antisense
Sequence Source Affymetrix Proprietary Database