[Home] | [Total List]

[190877_at] Zinc metalloprotease

Description C07D10.4 /REP_DB=WormBase Gene ID /WP=CE01151 /TR=SW:P55113 /GB=AAK31398.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=Zinc metalloprotease
Cluster 6grp_highest_10_10 > 08      6grp_high1_10_10 > 80      4grp_high_8_8 > 54      6grp_highest_nonorm > 72      6grp_total > 82      4grp_total > 57      6grp_cgc > 74      6grp_high1_sub > 02_03_04_05      6grp_cgc_sub > 02_03_04_05      6grp_rule_based > S2      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 895
1 2 3 4 range
A 155.4
(-2.7)
P 		882.2
(3)
P 		859.6
(2.8)
P 		111.6
(-3)
A 		771
B 136.6
(-2.9)
P 		836.8
(2.4)
P 		913
(3)
P 		117.8
(-3)
P 		795
C 170.7
(-2.6)
P 		751.6
(1.3)
P 		1006.4
(3)
P 		111.2
(-3)
A 		895
avr 154.2
(-2.7) 		823.5
(2.2) 		926.3
(3) 		113.5
(-3) 		813

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 363
1 2 3 4 5 6 range
A 184.2
(-3)
P 		441.3
(1.9)
P 		497.9
(3)
P 		438.3
(1.9)
P 		457.7
(2.2)
P 		225.9
(-2.2)
P 		314
B 228.1
(-3)
P 		545
(3)
P 		525.5
(2.6)
P 		424.4
(0.7)
P 		476
(1.7)
P 		313.4
(-1.4)
P 		317
C 211.7
(-3)
P 		547.6
(3)
P 		361.3
(-0.3)
P 		534.7
(2.8)
P 		361.4
(-0.3)
P 		272.6
(-1.9)
P 		336
avr 208
(-3) 		511.3
(3) 		461.6
(2) 		465.8
(2.1) 		431.7
(1.4) 		270.6
(-1.8) 		303
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 335
1 2 3 4 range
A 56.6
(-1.8)
P 		191.5
(2)
P 		224.7
(3)
P 		16.3
(-3)
A 		208
B 43.6
(-2.4)
P 		206.7
(2.8)
P 		211.6
(3)
P 		25.1
(-3)
P 		187
C 56.5
(-2.3)
P 		216.1
(0.6)
P 		350.8
(3)
P 		18.7
(-3)
A 		332
avr 52.2
(-2.2) 		204.8
(1.6) 		262.4
(3) 		20
(-3) 		242

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 159
1 2 3 4 5 6 range
A 34
(-3)
P 		157
(3)
P 		108.4
(0.6)
P 		111.2
(0.8)
P 		138.1
(2.1)
P 		55
(-2)
P 		123
B 79.4
(-3)
P 		181.4
(2.4)
P 		127.6
(-0.5)
P 		112.4
(-1.3)
P 		193.4
(3)
P 		116.9
(-1)
P 		114
C 78.5
(-3)
P 		167.1
(3)
P 		92
(-2.1)
P 		107.5
(-1)
P 		116.9
(-0.4)
P 		91.3
(-2.1)
P 		89
avr 64
(-3) 		168.5
(3) 		109.3
(-0.4) 		110.4
(-0.3) 		149.5
(1.9) 		87.7
(-1.6) 		105
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190877_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.4530
Sequence Type Exemplar sequence
Representative Public ID C07D10.4 NCBI
Target Description C07D10.4 /REP_DB=WormBase Gene ID /WP=CE01151 /TR=SW:P55113 /GB=AAK31398.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=Zinc metalloprotease
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063151(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063151 NCBI Caenorhabditis elegans Nematode AStacin protease family member (nas-7) (nas-7) mRNA, complete cds. 11/11 None
SNAP00000000401 ENSEMBL cdna:SNAP chromosome:CEL140:II:7400654:7402636:-1 11/11 None
GENEFINDER00000000406 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:7400654:7402645:-1 11/11 None
C07D10.4 ENSEMBL cdna:known chromosome:CEL140:II:7400654:7402636:-1 gene:C07D10.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:7400650-7402633(-) 100.0 100.0
Public Domain and Genome References
Gene Title Zinc metalloprotease
Gene Symbol nas-7
Ensembl C07D10.4
Entrez Gene 182368 Entrez gene
SwissProt P55113 EMBL-EBI
WormBase CE34663 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1633920_AT dm
DROSGENOME1:150500_AT dm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8237 metallopeptidase activity inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
8533 astacin activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK31398 Nematode astacin protease protein 7 [Caenorhabditis elegans] ref|NP_495552.2| Nematode AStacin protease family member (nas-7) [Caenorhabditis elegans] sp|P55113|NAS7_CAEEL Zinc metalloproteinase nas-7 precursor (Nematode astacin 7) 0.0
blast CAE67612 Hypothetical protein CBG13159 [Caenorhabditis briggsae] 0.0
blast CAD99206 NAS-7 protein [Caenorhabditis elegans] 1.0E-159
Protein Domains
Database ID Description E-Value
Pfam IPR001506 EMBL-EBI Peptidase M12A, astacin 3.6E-113
Pfam IPR003582 EMBL-EBI Metridin-like ShK toxin 7.3E-11
Pfam IPR001506 EMBL-EBI Peptidase M12A, astacin 3.6E-113
Pfam IPR003582 EMBL-EBI Metridin-like ShK toxin 7.3E-11
Sequence
Target Sequence 
>C. ELEGANS:190877_AT
tgcaaccatcggaaacgctcgtgacttttctgatgtggatatttcaaaaatcaaccgaat
gtacaattgcccagttgaaaagagtgtgacagctccatttgcacgagcacggcacgttcc
aatatattcaccacaataccataaatatgaagatcgtccaaagattccacttcgatcatt
tgatatgcaacaaggtccaattaatccaccaatggcacaaataccatcacaaagtcttgt
tgtttcaagtagctcaggacgggttaattataatagcaataaaccatcatctcgtaagtt
atatgcattttatggggaagaagaattaattttagaatgcgaggatcggataactgtatg
ctggtggacagcagatcgttgtaggtctcctgcaatttatcaagtcat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGCAACCATCGGAAACGCTCGTGAC 186 575 825 Antisense
CGCTCGTGACTTTTCTGATGTGGAT 672 255 840 Antisense
AACCGAATGTACAATTGCCCAGTTG 678 145 877 Antisense
GTGACAGCTCCATTTGCACGAGCAC 274 481 910 Antisense
CGGCACGTTCCAATATATTCACCAC 189 243 934 Antisense
AAGATCGTCCAAAGATTCCACTTCG 194 155 974 Antisense
GATTCCACTTCGATCATTTGATATG 543 433 987 Antisense
GGTCCAATTAATCCACCAATGGCAC 274 499 1018 Antisense
GGATCGGATAACTGTATGCTGGTGG 94 513 1167 Antisense
ACAGCAGATCGTTGTAGGTCTCCTG 384 109 1192 Antisense
GGTCTCCTGCAATTTATCAAGTCAT 102 503 1208 Antisense
Sequence Source Affymetrix Proprietary Database