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[190848_at] Tyrosine-phosphatase

Description B0280.11 /REP_DB=WormBase Gene ID /WP=CE00818 /TR=SW:P42083 /GB=AAA19089.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=Tyrosine-phosphatase
Cluster 6grp_total > 87      4grp_total > 36      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 4
1 2 3 4 range
A 4.5
(3)
A 		3
(-2.3)
A 		2.8
(-3)
A 		3.6
(-0.2)
A 		2
B 3.9
(3)
A 		3.3
(1.3)
A 		3.2
(1)
A 		1.8
(-3)
A 		2
C 2.4
(-2.7)
A 		5.7
(3)
A 		2.2
(-3)
A 		3.8
(-0.3)
A 		4
avr 3.6
(1.2) 		4
(3) 		2.7
(-3) 		3.1
(-1.2) 		1

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 295
1 2 3 4 5 6 range
A 6.1
(-2.9)
A 		3.4
(-3)
A 		2.5
(-3)
A 		54.6
(-1.9)
A 		113
(-0.8)
P 		297.8
(3)
P 		295
B 2.5
(-3)
A 		2.5
(-3)
A 		5.9
(-2.9)
A 		36.5
(-2.1)
A 		151.5
(0.9)
P 		229.8
(3)
P 		227
C 2.5
(-3)
A 		5.7
(-2.9)
A 		2.5
(-3)
A 		25.7
(-2.5)
A 		116.9
(-0.3)
P 		258.9
(3)
P 		256
avr 3.7
(-3) 		3.9
(-3) 		3.6
(-3) 		38.9
(-2.2) 		127.1
(-0.1) 		262.2
(3) 		259
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1
1 2 3 4 range
A 1.6
(3)
A 		0.7
(-1.9)
A 		0.7
(-1.9)
A 		0.5
(-3)
A 		1
B 1.2
(3)
A 		0.8
(0)
A 		0.7
(-0.8)
A 		0.4
(-3)
A 		1
C 0.8
(-1.8)
A 		1.6
(3)
A 		0.8
(-1.8)
A 		0.6
(-3)
A 		1
avr 1.2
(3) 		1
(1.3) 		0.7
(-1.3) 		0.5
(-3) 		1

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 86
1 2 3 4 5 6 range
A 1.1
(-3)
A 		1.2
(-2.9)
A 		0.5
(-3)
A 		13.8
(-1.9)
A 		34.1
(-0.2)
P 		72.5
(3)
P 		72
B 0.9
(-3)
A 		0.8
(-3)
A 		1.4
(-3)
A 		9.7
(-2.4)
A 		61.6
(1.3)
P 		85.7
(3)
P 		85
C 0.9
(-3)
A 		1.7
(-2.9)
A 		0.6
(-3)
A 		5.2
(-2.7)
A 		37.8
(-0.4)
P 		86.7
(3)
P 		86
avr 1
(-3) 		1.2
(-3) 		0.8
(-3) 		9.6
(-2.3) 		44.5
(0.2) 		81.6
(3) 		81
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190848_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7461
Sequence Type Exemplar sequence
Representative Public ID B0280.11 NCBI
Target Description B0280.11 /REP_DB=WormBase Gene ID /WP=CE00818 /TR=SW:P42083 /GB=AAA19089.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=Tyrosine-phosphatase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066159(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066159 NCBI Caenorhabditis elegans B0280.11 (Tyrosine-phosphatase) mRNA, complete cds. 10/11 None
SNAP00000041616 ENSEMBL cdna:SNAP chromosome:CEL140:III:7135008:7135987:-1 11/11 None
GENEFINDER00000041620 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:7135008:7135987:-1 11/11 None
B0280.11 ENSEMBL cdna:known chromosome:CEL140:III:7135008:7138170:-1 gene:B0280.11 10/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:7135005-7138168(-) 100.0 100.0
Public Domain and Genome References
Gene Title Tyrosine-phosphatase
Ensembl B0280.11
Entrez Gene 175997 Entrez gene
SwissProt P42083 EMBL-EBI
WormBase CE29534 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6470 protein amino acid dephosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3676 nucleic acid binding inferred from electronic annotation QuickGO AmiGO
4725 protein tyrosine phosphatase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA19089 Hypothetical protein B0280.11 [Caenorhabditis elegans] ref|NP_498560.1| B0280.11 [Caenorhabditis elegans] sp|P42083|YKCA_CAEEL Hypothetical protein B0280.11 in chromosome III 0.0
blast T15305 hypothetical protein B0280.11 - Caenorhabditis elegans 0.0
blast CAB01189 Hypothetical protein F40G12.10 [Caenorhabditis elegans] ref|NP_506537.1| F40G12.10 [Caenorhabditis elegans] 1.0E-149
blast T15305 hypothetical protein B0280.11 - Caenorhabditis elegans 1.0E-118
blast T15305 hypothetical protein B0280.11 - Caenorhabditis elegans 1.0E-117
blast AAA19089 Hypothetical protein B0280.11 [Caenorhabditis elegans] ref|NP_498560.1| B0280.11 [Caenorhabditis elegans] sp|P42083|YKCA_CAEEL Hypothetical protein B0280.11 in chromosome III 1.0E-112
blast AAA19089 Hypothetical protein B0280.11 [Caenorhabditis elegans] ref|NP_498560.1| B0280.11 [Caenorhabditis elegans] sp|P42083|YKCA_CAEEL Hypothetical protein B0280.11 in chromosome III 1.0E-100
Protein Domains
Database ID Description E-Value
Pfam IPR004087 EMBL-EBI KH 3.4E-7
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 2.2E-22
Pfam IPR004087 EMBL-EBI KH 7.5E-7
Pfam IPR004087 EMBL-EBI KH 3.4E-7
Sequence
Target Sequence 
>C. ELEGANS:190848_AT
aatgctcataatcttctagttcgtgaaatcaagcgtgtttatgacgcagaaatgatcgtg
aatggtctcggaagcggaacaccgccaccctctttcctcggaagagctaatgctggaaaa
gatgaatcaatggatctatcctcgcttagaaatcttctgaaggatgatccgttgttgatg
acaccaccacctggactgcaacgtcgccagactttcagcccaatgactttgtcattgatt
ggaggtttgaaaaatggttgttctgagaatgaaaataaggaagaggggaacaatactaat
ccagtcggacgcctcattggtccacgtggaatgacaattcgccaactcgaaaaagatctc
ggatgcaagctgttcattcgcggaaaaggatgtacaaaagatgatgccaaagaagaacgt
cttcgtgaacgtgttggctgggagcatctcaaagaaccgattcacgtgatgatttcagtc
cgctccgattcggaagaggctgcatccgagaaactgtcatctatcaagaaaatgcttcaa
gaatttttggaacatactgactcggaactcaaacgctctcagcttatgca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AATGCTCATAATCTTCTAGTTCGTG 545 165 1399 Antisense
ATGGTCTCGGAAGCGGAACACCGCC 164 49 1460 Antisense
CACCCTCTTTCCTCGGAAGAGCTAA 409 197 1484 Antisense
CTATCCTCGCTTAGAAATCTTCTGA 328 225 1534 Antisense
TGATCCGTTGTTGATGACACCACCA 185 565 1563 Antisense
GACTTTCAGCCCAATGACTTTGTCA 232 373 1608 Antisense
AATACTAATCCAGTCGGACGCCTCA 161 171 1690 Antisense
AGATCTCGGATGCAAGCTGTTCATT 704 65 1752 Antisense
GAACGTGTTGGCTGGGAGCATCTCA 494 347 1825 Antisense
AGGCTGCATCCGAGAAACTGTCATC 110 55 1895 Antisense
AACTCAAACGCTCTCAGCTTATGCA 52 141 1964 Antisense
Sequence Source Affymetrix Proprietary Database