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[190825_at] ring canal protein like

Description C53A5.11 /REP_DB=WormBase Gene ID /WP=CE08960 /TR=O17702 /GB=CAB03991.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=ring canal protein like
Cluster 6grp_total > 42      4grp_total > 14      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 60
1 2 3 4 range
A 36.7
(0.4)
A 		18.7
(-1.5)
A 		5.3
(-3)
A 		60.6
(3)
A 		55
B 8.4
(-2)
A 		4.4
(-3)
A 		19.7
(0.8)
A 		28.7
(3)
A 		24
C 63.5
(3)
A 		3.5
(-3)
A 		14.4
(-1.9)
A 		47.8
(1.4)
A 		60
avr 36.2
(1.5) 		8.9
(-3) 		13.1
(-2.3) 		45.7
(3) 		37

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 44
1 2 3 4 5 6 range
A 33.9
(0.8)
A 		22.4
(-1.3)
A 		45.4
(3)
A 		13.6
(-3)
A 		45.3
(3)
A 		28.1
(-0.3)
A 		32
B 26.1
(1.7)
A 		7.9
(-1.8)
A 		27.7
(2)
A 		33
(3)
A 		18
(0.1)
A 		1.6
(-3)
A 		31
C 4.4
(-2.2)
A 		26.6
(3)
A 		24.9
(2.6)
A 		15.1
(0.3)
A 		6.9
(-1.7)
A 		1.2
(-3)
A 		25
avr 21.5
(-0) 		19
(-0.7) 		32.7
(3) 		20.6
(-0.2) 		23.4
(0.5) 		10.3
(-3) 		22
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 20
1 2 3 4 range
A 13.4
(3)
A 		4.1
(-1.7)
A 		1.4
(-3)
A 		8.9
(0.8)
A 		12
B 2.7
(-1.1)
A 		1.1
(-3)
A 		4.6
(1.2)
A 		6.1
(3)
A 		5
C 21
(3)
A 		1
(-3)
A 		5
(-1.8)
A 		8.1
(-0.9)
A 		20
avr 12.4
(3) 		2.1
(-3) 		3.7
(-2.1) 		7.7
(0.3) 		10

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 13
1 2 3 4 5 6 range
A 6.2
(-1.4)
A 		8
(-0.3)
A 		9.9
(0.8)
A 		3.4
(-3)
A 		13.7
(3)
A 		6.8
(-1)
A 		10
B 9.1
(3)
A 		2.6
(-1.6)
A 		6.7
(1.3)
A 		8.7
(2.7)
A 		7.3
(1.7)
A 		0.6
(-3)
A 		9
C 1.6
(-2.1)
A 		8.1
(3)
A 		6.3
(1.6)
A 		3
(-1)
A 		2.2
(-1.6)
A 		0.4
(-3)
A 		8
avr 5.6
(0.5) 		6.2
(1.2) 		7.6
(2.9) 		5
(-0.2) 		7.7
(3) 		2.6
(-3) 		5
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190825_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13916
Sequence Type Exemplar sequence
Representative Public ID C53A5.11 NCBI
Target Description C53A5.11 /REP_DB=WormBase Gene ID /WP=CE08960 /TR=O17702 /GB=CAB03991.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=ring canal protein like
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074206(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074206 NCBI Caenorhabditis elegans C53A5.11 (C53A5.11) mRNA, complete cds. 11/11 None
SNAP00000009293 ENSEMBL cdna:SNAP chromosome:CEL140:V:14565478:14567228:1 11/11 None
GENEFINDER00000009297 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:14562201:14567228:1 11/11 None
C53A5.11 ENSEMBL cdna:known chromosome:CEL140:V:14565154:14567228:1 gene:C53A5.11 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:14565153-14567228(+) 100.0 100.0
Public Domain and Genome References
Gene Title ring canal protein like
Ensembl C53A5.11
Entrez Gene 183741 Entrez gene
SwissProt O17702 EMBL-EBI
WormBase CE08960 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4289 subtilase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB03991 Hypothetical protein C53A5.11 [Caenorhabditis elegans] ref|NP_506607.1| C53A5.11 [Caenorhabditis elegans] 0.0
blast CAB03987 Hypothetical protein C53A5.6 [Caenorhabditis elegans] ref|NP_506602.1| C53A5.6 [Caenorhabditis elegans] 1.0E-96
blast CAB03987 Hypothetical protein C53A5.6 [Caenorhabditis elegans] ref|NP_506602.1| C53A5.6 [Caenorhabditis elegans] 2.0E-96
blast CAB03987 Hypothetical protein C53A5.6 [Caenorhabditis elegans] ref|NP_506602.1| C53A5.6 [Caenorhabditis elegans] 3.0E-96
blast CAE56161 Hypothetical protein CBG23781 [Caenorhabditis briggsae] 9.0E-91
blast CAE56161 Hypothetical protein CBG23781 [Caenorhabditis briggsae] 1.0E-90
Protein Domains
Database ID Description E-Value
Pfam IPR006652 EMBL-EBI Kelch repeat 1.3E-9
Pfam IPR006652 EMBL-EBI Kelch repeat 2.5E-11
Pfam IPR006652 EMBL-EBI Kelch repeat 2.7E-8
Pfam IPR006652 EMBL-EBI Kelch repeat 3.0E-16
Pfam IPR006652 EMBL-EBI Kelch repeat 2.3E-4
Pfam IPR006652 EMBL-EBI Kelch repeat 1.3E-9
Pfam IPR006652 EMBL-EBI Kelch repeat 2.5E-11
Pfam IPR006652 EMBL-EBI Kelch repeat 2.7E-8
Pfam IPR006652 EMBL-EBI Kelch repeat 3.0E-16
Pfam IPR006652 EMBL-EBI Kelch repeat 2.3E-4
Pfam IPR006652 EMBL-EBI Kelch repeat 1.3E-9
Pfam IPR006652 EMBL-EBI Kelch repeat 2.5E-11
Pfam IPR006652 EMBL-EBI Kelch repeat 2.7E-8
Pfam IPR006652 EMBL-EBI Kelch repeat 3.0E-16
Pfam IPR006652 EMBL-EBI Kelch repeat 2.3E-4
Pfam IPR002651 EMBL-EBI Protein of unknown function DUF32 1.0E-13
Pfam IPR002651 EMBL-EBI Protein of unknown function DUF32 4.2E-53
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000009297 6 39-61,74-96,101-123,144-166,176-198,240-262
Sequence
Target Sequence 
>C. ELEGANS:190825_AT
ggctaatgcatggacgaactcggacatctgcatgtattcatgaggacgcaatttacgcag
tgggaggatacgatgcgacatatatgagttcagttgagatttatgatattaaaactggag
gagactggaccacaggcccatcattaaataaccgtcgcgccgatgcatcagttgtatcat
tttatggacaactttttgtgcttggcggcttcaatggaaaagattatgaagagactattg
agaaattatcagattcgaaagacaagtttgaggtttgtggtaatatggttggacgtgcag
gttttggtgcatgtgtattccgtggaagaatctatgtggctggtggatggaacacccctt
gcaacacattaaaaacctttcaaagttacgatccattgacaaatacatggaaagatgagc
catcgatgaatacgggaagaaagtattttaagcttcatgctacgaatgaagcaatctatg
caattcgtggatgttctcatgactgggatct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGCTAATGCATGGACGAACTCGGAC 146 537 740 Antisense
GAACTCGGACATCTGCATGTATTCA 475 349 755 Antisense
GAGGACGCAATTTACGCAGTGGGAG 109 405 781 Antisense
ACTGGAGGAGACTGGACCACAGGCC 679 95 853 Antisense
GGACCACAGGCCCATCATTAAATAA 640 501 866 Antisense
ATTAAATAACCGTCGCGCCGATGCA 483 11 882 Antisense
GGACAACTTTTTGTGCTTGGCGGCT 636 525 925 Antisense
ATGGTTGGACGTGCAGGTTTTGGTG 332 49 1024 Antisense
TTTGGTGCATGTGTATTCCGTGGAA 205 667 1042 Antisense
GGCTGGTGGATGGAACACCCCTTGC 412 539 1077 Antisense
GTGGATGTTCTCATGACTGGGATCT 66 491 1226 Antisense
Sequence Source Affymetrix Proprietary Database