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[190817_s_at] serine/threonine kinase

Description Y51B9A.9 /REP_DB=WormBase Gene ID /WP=CE19219 /TR=Q9XXC0 /GB=CAA19542.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_high1_10_10 > 82      6grp_total > 73      4grp_total > 23      6grp_high1_sub > 04      6grp_total_sub > Hat      6grp_rule_based > S4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 155
1 2 3 4 range
A 217.6
(3)
P 		81.4
(-3)
A 		83.1
(-2.9)
A 		150.1
(0)
A 		136
B 196.8
(3)
P 		90.2
(-1.8)
A 		62.8
(-3)
A 		167.3
(1.7)
A 		134
C 163.1
(1.2)
A 		76.7
(-3)
A 		103.1
(-1.7)
A 		198.7
(3)
P 		122
avr 192.5
(3) 		82.8
(-3) 		83
(-3) 		172
(1.9) 		110

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 532
1 2 3 4 5 6 range
A 193.2
(-3)
P 		268.5
(-1.3)
P 		408.6
(1.8)
P 		452.7
(2.7)
P 		465.2
(3)
P 		274.4
(-1.2)
P 		272
B 173.3
(-3)
A 		244
(-1.6)
P 		432
(2.1)
P 		462.7
(2.8)
P 		474.8
(3)
P 		243.5
(-1.6)
P 		302
C 149.1
(-3)
A 		304.8
(-1.2)
P 		355.6
(-0.7)
P 		681.3
(3)
P 		319.9
(-1.1)
P 		311.6
(-1.2)
P 		532
avr 171.9
(-3) 		272.4
(-1.3) 		398.7
(0.8) 		532.2
(3) 		420
(1.1) 		276.5
(-1.3) 		360
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 65
1 2 3 4 range
A 79.2
(3)
P 		17.7
(-3)
A 		21.7
(-2.6)
A 		22
(-2.6)
A 		62
B 62.8
(3)
P 		22.3
(-2)
A 		14.6
(-3)
A 		35.7
(-0.4)
A 		48
C 54
(3)
A 		22
(-3)
A 		35.9
(-0.4)
A 		33.5
(-0.8)
P 		32
avr 65.3
(3) 		20.7
(-3) 		24.1
(-2.5) 		30.4
(-1.7) 		45

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 157
1 2 3 4 5 6 range
A 35.6
(-3)
P 		95.5
(0.4)
P 		89
(0.1)
P 		114.8
(1.5)
P 		140.4
(3)
P 		66.8
(-1.2)
P 		105
B 60.3
(-3)
A 		81.2
(-2.1)
P 		104.9
(-1)
P 		122.6
(-0.2)
P 		192.9
(3)
P 		90.8
(-1.6)
P 		133
C 55.2
(-3)
A 		93
(-0.2)
P 		90.5
(-0.4)
P 		137
(3)
P 		103.5
(0.5)
P 		104.3
(0.6)
P 		82
avr 50.4
(-3) 		89.9
(-0.5) 		94.8
(-0.2) 		124.8
(1.7) 		145.6
(3) 		87.3
(-0.7) 		95
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190817_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3828
Sequence Type Exemplar sequence
Representative Public ID Y51B9A.9 NCBI
Target Description Y51B9A.9 /REP_DB=WormBase Gene ID /WP=CE19219 /TR=Q9XXC0 /GB=CAA19542.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063601(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063601 NCBI Caenorhabditis elegans Y51B9A.9 (Y51B9A.9) mRNA, complete cds. 11/11 None
GENEFINDER00000039084 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:9395477:9398008:-1 11/11 None
Y51B9A.9 ENSEMBL cdna:known chromosome:CEL140:II:9395477:9397446:-1 gene:Y51B9A.9 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000039072 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:9395473-9397443(-) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Ensembl Y51B9A.9
Entrez Gene 174489 Entrez gene
SwissProt Q9XXC0 EMBL-EBI
WormBase CE19219 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA19542 Hypothetical protein Y51B9A.9 [Caenorhabditis elegans] ref|NP_496002.1| Y51B9A.9 [Caenorhabditis elegans] 0.0
blast CAB54196 Hypothetical protein C49C3.10 [Caenorhabditis elegans] ref|NP_001023086.1| C49C3.10 [Caenorhabditis elegans] 1.0E-120
blast CAE57479 Hypothetical protein CBG00447 [Caenorhabditis briggsae] 1.0E-115
blast CAE57479 Hypothetical protein CBG00447 [Caenorhabditis briggsae] 1.0E-114
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 1.0E-13
hanks 3.1.1 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; CDC2Hs 3.0E-60
hanks 3.1.1 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; CDC2Hs 2.0E-60
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 5.6E-38
Pfam IPR000719 EMBL-EBI Protein kinase 5.6E-38
Sequence
Target Sequence 
>C. ELEGANS:190817_S_AT
aatcctattcacaggccaaacccaaattgatcaattcttccaaatagtccggtttcttgg
gaatccagatctgtcattctatatgcagatgcccgattctgctagaacattcttcttggg
ccttccaatgaatcaatatcaaaaacctacaaacatacatgaacacttccctaatagtct
gttcctcgacacgatgatttctgaaccgatagactgcgatctggcacgtgatctgctatt
ccgcatgctagtgataaatccagacgatcgaattgatattcagaaaatattggtgcatcc
ttatttagaagaagtatggtcgaatattgtgattgacaataaaattgaagaaaaatatcc
tccgatcgctcttcgaagattttttgaatttcaagctttttctcctcccagacaaatgaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AATCCTATTCACAGGCCAAACCCAA 633 165 669 Antisense
GATCAATTCTTCCAAATAGTCCGGT 452 421 697 Antisense
GTCCGGTTTCTTGGGAATCCAGATC 696 475 715 Antisense
GATGCCCGATTCTGCTAGAACATTC 122 415 756 Antisense
CATTCTTCTTGGGCCTTCCAATGAA 697 215 776 Antisense
AACACTTCCCTAATAGTCTGTTCCT 168 135 830 Antisense
GTCTGTTCCTCGACACGATGATTTC 484 471 845 Antisense
ACTGCGATCTGGCACGTGATCTGCT 207 97 881 Antisense
TGATCTGCTATTCCGCATGCTAGTG 235 565 897 Antisense
AAGAAAAATATCCTCCGATCGCTCT 409 151 1016 Antisense
CTTTTTCTCCTCCCAGACAAATGAA 190 223 1064 Antisense
Sequence Source Affymetrix Proprietary Database