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[190795_s_at] serine/threonine kinase /// serine/threonine kinase

Description F35C11.3 /REP_DB=WormBase Gene ID /WP=CE02210 /TR=Q20018 /GB=CAA90241.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster 6grp_total > 77      4grp_total > 38      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 83
1 2 3 4 range
A 98.6
(3)
P 		43.8
(-1)
A 		16.1
(-3)
A 		33.7
(-1.7)
A 		83
B 55.9
(3)
P 		55.2
(2.9)
A 		22.5
(-3)
A 		30
(-1.7)
A 		33
C 92.7
(3)
P 		42.2
(-2.3)
A 		35.6
(-3)
A 		89.7
(2.7)
P 		57
avr 82.4
(3) 		47.1
(-0.7) 		24.7
(-3) 		51.1
(-0.3) 		58

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 280
1 2 3 4 5 6 range
A 7.6
(-3)
A 		22.5
(-2.7)
A 		55.4
(-2)
A 		43.2
(-2.2)
A 		86
(-1.3)
P 		287.3
(3)
P 		280
B 18.1
(-3)
A 		25.6
(-2.8)
A 		35.9
(-2.4)
A 		45.8
(-2.1)
A 		121.3
(0.2)
P 		209.5
(3)
P 		191
C 44.5
(-2.2)
A 		82.6
(-1.1)
M 		18.8
(-3)
A 		45.7
(-2.2)
A 		81.9
(-1.1)
P 		221.8
(3)
P 		203
avr 23.4
(-3) 		43.6
(-2.4) 		36.7
(-2.6) 		44.9
(-2.4) 		96.4
(-1) 		239.5
(3) 		216
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 32
1 2 3 4 range
A 35.9
(3)
P 		9.5
(-2)
A 		4.2
(-3)
A 		4.9
(-2.9)
A 		32
B 17.8
(3)
P 		13.6
(1)
A 		5.2
(-3)
A 		6.4
(-2.4)
A 		13
C 30.7
(3)
P 		12.1
(-3)
A 		12.4
(-2.9)
A 		15.1
(-2)
P 		19
avr 28.1
(3) 		11.7
(-1.7) 		7.3
(-3) 		8.8
(-2.6) 		21

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 77
1 2 3 4 5 6 range
A 1.4
(-3)
A 		8
(-2.4)
A 		12.1
(-2.1)
A 		11
(-2.2)
A 		26
(-0.8)
P 		69.9
(3)
P 		69
B 6.3
(-3)
A 		8.5
(-2.8)
A 		8.7
(-2.8)
A 		12.1
(-2.5)
A 		49.3
(0.6)
P 		78.1
(3)
P 		72
C 16.5
(-2)
A 		25.2
(-1.2)
M 		4.8
(-3)
A 		9.2
(-2.6)
A 		26.5
(-1.1)
P 		74.3
(3)
P 		70
avr 8.1
(-3) 		13.9
(-2.5) 		8.5
(-3) 		10.8
(-2.8) 		33.9
(-0.7) 		74.1
(3) 		66
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190795_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3153
Sequence Type Exemplar sequence
Representative Public ID F35C11.3 NCBI
Target Description F35C11.3 /REP_DB=WormBase Gene ID /WP=CE02210 /TR=Q20018 /GB=CAA90241.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063336(11), NM_063387(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063336 NCBI Caenorhabditis elegans F35C11.3 (F35C11.3) mRNA, complete cds. 11/11 None
NM_063387 NCBI Caenorhabditis elegans M05D6.1 (M05D6.1) mRNA, complete cds. 11/11 None
SNAP00000015527 ENSEMBL cdna:SNAP chromosome:CEL140:II:8473842:8475193:-1 11/11 None
GENEFINDER00000015539 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:8473842:8475193:-1 11/11 None
SNAP00000018023 ENSEMBL cdna:SNAP chromosome:CEL140:II:8246835:8248186:1 11/11 None
GENEFINDER00000018032 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:8246835:8248186:1 11/11 None
F35C11.3 ENSEMBL cdna:known chromosome:CEL140:II:8246835:8248186:1 gene:F35C11.3 11/11 None
M05D6.1 ENSEMBL cdna:known chromosome:CEL140:II:8473842:8475193:-1 gene:M05D6.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:8246831-8248183(+) 100.0 100.0
chrII:8473838-8475190(-) 99.63 99.63
Public Domain and Genome References
Gene Title serine/threonine kinase
serine/threonine kinase
Ensembl F35C11.3
M05D6.1
Entrez Gene 174324 Entrez gene
174354 Entrez gene
SwissProt Q20018 EMBL-EBI
Q21521 EMBL-EBI
WormBase CE02210 Wormbase
CE03499 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA90241 Hypothetical protein F35C11.3 [Caenorhabditis elegans] ref|NP_495737.1| F35C11.3 [Caenorhabditis elegans] 0.0
blast CAA91411 Hypothetical protein M05D6.1 [Caenorhabditis elegans] ref|NP_495788.1| M05D6.1 [Caenorhabditis elegans] 0.0
blast CAE72538 Hypothetical protein CBG19720 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.0E-21
Pfam IPR000719 EMBL-EBI Protein kinase 2.4E-28
Sequence
Target Sequence 
>C. ELEGANS:190795_S_AT
agttgtctacattttcgattttggcttatcacgtcagatcatgcttccggatgcaagtgg
caagctgaaattgagagagccacgtaacaagtcaatgtttcgtggaactgttcgctattg
tagtttgaatgtgcatttgcataaggagcaagggagacatgatgatttgtatggagcact
gtatgccatgatcgagactgctacctccactcttccttggaaaggaaaaccgaaaaaaga
aacttctgctttgaaagagaagactaccgatgttcagctgtgcaagggttgtccaaaatc
attcttggaaattgcgactacccttcggaagttaacttacaaagagacacctccatatgg
cagtttcatggagaagttgaaggctgatcttccaaaaggagtcaagatgactgatccatt
cgaatggaacttgaaaggtgcattggatgagaacaacaatggaaacaagtcggatcgtga
ggatgcagagcgtggcggtggagcagatacag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGTTGTCTACATTTTCGATTTTGGC 563 65 480 Antisense
GGCTTATCACGTCAGATCATGCTTC 233 537 502 Antisense
ATCATGCTTCCGGATGCAAGTGGCA 505 29 517 Antisense
GAGAGAGCCACGTAACAAGTCAATG 424 393 552 Antisense
TATGCCATGATCGAGACTGCTACCT 213 657 661 Antisense
AGACTACCGATGTTCAGCTGTGCAA 253 71 740 Antisense
GTTCAGCTGTGCAAGGGTTGTCCAA 404 445 751 Antisense
GAAATTGCGACTACCCTTCGGAAGT 693 361 787 Antisense
GAGACACCTCCATATGGCAGTTTCA 455 393 823 Antisense
GATCGTGAGGATGCAGAGCGTGGCG 18 419 952 Antisense
GAGCGTGGCGGTGGAGCAGATACAG 246 387 967 Antisense
Sequence Source Affymetrix Proprietary Database