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[190794_at] tyrosine-protein kinase

Description ZK622.1 /REP_DB=WormBase Gene ID /WP=CE05098 /TR=Q23554 /GB=AAA81104.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=tyrosine-protein kinase
Cluster 6grp_total > 79      4grp_total > 0      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 67
1 2 3 4 range
A 35.2
(-3)
A 		48.6
(-1.2)
A 		80.5
(3)
M 		67.1
(1.2)
A 		45
B 17.1
(-3)
A 		18.6
(-2.6)
A 		33.6
(1.6)
A 		38.4
(3)
A 		21
C 84.3
(3)
P 		33
(-2.1)
A 		24.2
(-3)
A 		75.5
(2.1)
A 		60
avr 45.5
(-0.3) 		33.4
(-3) 		46.1
(-0.2) 		60.3
(3) 		27

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 74
1 2 3 4 5 6 range
A 6.5
(-3)
A 		27.7
(-1)
A 		20.2
(-1.7)
A 		33
(-0.5)
A 		59.2
(2)
A 		69.8
(3)
M 		63
B 43.5
(0.1)
A 		34.1
(-0.7)
A 		30
(-1)
A 		6.5
(-3)
A 		38.3
(-0.4)
P 		78.7
(3)
P 		72
C 9.2
(-2.6)
A 		71.3
(3)
P 		22.5
(-1.4)
A 		4.8
(-3)
A 		51
(1.2)
P 		54.8
(1.5)
P 		67
avr 19.7
(-2.4) 		44.4
(0.4) 		24.2
(-1.9) 		14.8
(-3) 		49.5
(0.9) 		67.8
(3) 		53
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 23
1 2 3 4 range
A 12.8
(-1.4)
A 		10.6
(-2.6)
A 		21
(3)
M 		9.8
(-3)
A 		11
B 5.4
(-1.7)
A 		4.6
(-3)
A 		7.8
(2.3)
A 		8.2
(3)
A 		4
C 27.9
(3)
P 		9.5
(-2.7)
A 		8.4
(-3)
A 		12.7
(-1.7)
A 		20
avr 15.4
(3) 		8.2
(-3) 		12.4
(0.5) 		10.2
(-1.3) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 28
1 2 3 4 5 6 range
A 1.2
(-3)
A 		9.9
(0.1)
A 		4.4
(-1.9)
A 		8.4
(-0.4)
A 		17.9
(3)
A 		17
(2.7)
M 		17
B 15.1
(-0.1)
A 		11.4
(-0.9)
A 		7.3
(-1.8)
A 		1.7
(-3)
A 		15.5
(-0)
P 		29.4
(3)
P 		28
C 3.4
(-2.3)
A 		21.7
(3)
P 		5.7
(-1.6)
A 		1
(-3)
A 		16.5
(1.5)
P 		18.3
(2)
P 		21
avr 6.6
(-2) 		14.3
(0.6) 		5.8
(-2.3) 		3.7
(-3) 		16.6
(1.3) 		21.6
(3) 		18
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190794_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.4293
Sequence Type Exemplar sequence
Representative Public ID ZK622.1 NCBI
Target Description ZK622.1 /REP_DB=WormBase Gene ID /WP=CE05098 /TR=Q23554 /GB=AAA81104.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=tyrosine-protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_062593(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_062593 NCBI Caenorhabditis elegans ZK622.1 (ZK622.1) mRNA, complete cds. 11/11 None
SNAP00000008538 ENSEMBL cdna:SNAP chromosome:CEL140:II:5294512:5295564:1 11/11 None
GENEFINDER00000008554 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:5293924:5295564:1 11/11 None
ZK622.1 ENSEMBL cdna:known chromosome:CEL140:II:5293924:5295564:1 gene:ZK622.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:5293921-5295562(+) 100.0 100.0
Public Domain and Genome References
Gene Title tyrosine-protein kinase
Ensembl ZK622.1
Entrez Gene 191366 Entrez gene
SwissProt Q23554 EMBL-EBI
WormBase CE05098 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA81104 Hypothetical protein ZK622.1 [Caenorhabditis elegans] ref|NP_494994.1| ZK622.1 [Caenorhabditis elegans] 0.0
blast XP_623733 PREDICTED: similar to CG8874-PB, isoform B [Apis mellifera] 2.0E-69
blast XP_623692 PREDICTED: similar to GA21383-PA [Apis mellifera] 2.0E-69
Protein Families
Method ID Description E-Value
hanks 1.9.5 AGC group; AGC Other; DdK2 1.0E-62
hanks 1.9.5 AGC group; AGC Other; DdK2 6.0E-63
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 2.3E-62
Pfam IPR000980 EMBL-EBI SH2 motif 2.2E-16
Pfam IPR000719 EMBL-EBI Protein kinase 2.3E-62
Sequence
Target Sequence 
>C. ELEGANS:190794_AT
agtcaaggagctctcgactcttttctgaaaaatgagaagaacaatgtttctcttagagat
aaattgaaatactcatttgatgcttcgaaaggacttgaatatctccatcaacacggatgc
attcatcgtgacgtggcggctcgtaacttcttgatgcacaaaaatgttgtgaaaatcacg
gatttcgggctttcgaagcaactctccgatttggcgcacaaatacaagttgaaggatatt
caagcgaagcttccgatcagatggcttgctccagaagtcattgtcactgccacgtacact
ttcaagtcagatgtgtattccttcgggattcttttgtgggagattttcatggacggagcc
ataccgtatccaggaatgaaattggctgaagtgaagcagaaagtcaaaaatggatacaga
atggatgctcctgatcgaatgccagcgtttgttcgtaacat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGTCAAGGAGCTCTCGACTCTTTTC 429 59 676 Antisense
GATGCATTCATCGTGACGTGGCGGC 211 413 791 Antisense
CGGCTCGTAACTTCTTGATGCACAA 568 241 812 Antisense
GCTTTCGAAGCAACTCTCCGATTTG 148 305 864 Antisense
CTTCCGATCAGATGGCTTGCTCCAG 464 219 925 Antisense
TCCAGAAGTCATTGTCACTGCCACG 158 591 945 Antisense
ACTGCCACGTACACTTTCAAGTCAG 511 97 961 Antisense
AGTCAGATGTGTATTCCTTCGGGAT 684 61 980 Antisense
TGGACGGAGCCATACCGTATCCAGG 227 547 1025 Antisense
TGGATGCTCCTGATCGAATGCCAGC 68 551 1097 Antisense
GAATGCCAGCGTTTGTTCGTAACAT 590 329 1112 Antisense
Sequence Source Affymetrix Proprietary Database