[Home] | [Total List]

[190790_at] glutamyl-trna synthetase

Description ZC434.5 /REP_DB=WormBase Gene ID /WP=CE06580 /TR=Q23315 /GB=CAB00060.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=glutamyl-trna synthetase
Cluster 6grp_highest_10_10 > 53      6grp_high1_10_10 > 35      4grp_highest_8_8 > 26      4grp_high_8_8 > 59      6grp_highest_nonorm > 67      6grp_total > 35      4grp_total > 60      6grp_highest_sub > 02      6grp_cgc > 44      6grp_high1_sub > 02      6grp_cgc_sub > 02      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1244
1 2 3 4 range
A 2524.1
(0.7)
P 		2458.1
(0.3)
P 		2844.6
(3)
P 		1991.7
(-3)
P 		853
B 2636.6
(1.4)
P 		2727.3
(2)
P 		2908.9
(3)
P 		1868.3
(-3)
P 		1041
C 2720.8
(1.9)
P 		2354
(0.1)
P 		2946.9
(3)
P 		1703.4
(-3)
P 		1244
avr 2627.2
(1.4) 		2513.1
(0.8) 		2900.1
(3) 		1854.5
(-3) 		1046

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1095
1 2 3 4 5 6 range
A 1895
(-0.1)
P 		2458.5
(3)
P 		1716.3
(-1.1)
P 		1402.6
(-2.8)
P 		1367.9
(-3)
P 		1515.4
(-2.2)
P 		1091
B 2164.6
(2.3)
P 		2273.2
(3)
P 		1993.8
(1.2)
P 		1603.6
(-1.4)
P 		1363.6
(-3)
P 		1840.1
(0.1)
P 		910
C 1819.4
(-0.2)
P 		2295.3
(3)
P 		1867.4
(0.1)
P 		1395.4
(-3)
P 		1484.8
(-2.4)
P 		1826.3
(-0.1)
P 		900
avr 1959.7
(0.5) 		2342.3
(3) 		1859.2
(-0.1) 		1467.2
(-2.6) 		1405.4
(-3) 		1727.3
(-0.9) 		937
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 740
1 2 3 4 range
A 919
(3)
P 		533.6
(-0.7)
P 		743.6
(1.3)
P 		291.5
(-3)
P 		628
B 840.8
(3)
P 		673.6
(0.7)
P 		674.1
(0.7)
P 		398.1
(-3)
P 		443
C 900.7
(2)
P 		676.8
(0.2)
P 		1027.1
(3)
P 		287.2
(-3)
P 		740
avr 886.8
(3) 		628
(0.2) 		814.9
(2.2) 		325.6
(-3) 		561

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 594
1 2 3 4 5 6 range
A 349.3
(-3)
P 		874.4
(3)
P 		373.8
(-2.7)
P 		355.7
(-2.9)
P 		412.8
(-2.3)
P 		368.9
(-2.8)
P 		525
B 753.2
(2.9)
P 		756.6
(3)
P 		484.1
(-1.9)
P 		424.8
(-3)
P 		554
(-0.7)
P 		686.2
(1.7)
P 		332
C 674.4
(2.6)
P 		700.4
(3)
P 		475.3
(-0.2)
P 		280.6
(-3)
P 		480.5
(-0.1)
P 		611.4
(1.7)
P 		420
avr 592.3
(0.4) 		777.1
(3) 		444.4
(-1.7) 		353.7
(-3) 		482.4
(-1.2) 		555.5
(-0.1) 		423
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 190790_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.333
Sequence Type Exemplar sequence
Representative Public ID ZC434.5 NCBI
Target Description ZC434.5 /REP_DB=WormBase Gene ID /WP=CE06580 /TR=Q23315 /GB=CAB00060.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=glutamyl-trna synthetase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060310(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060310 NCBI Caenorhabditis elegans glutamyl(E)/glutaminyl(Q) tRNA Synthetase family member (ers-2) (ers-2) mRNA, complete cds. 11/11 None
SNAP00000018737 ENSEMBL cdna:SNAP chromosome:CEL140:I:10344535:10348933:1 11/11 None
GENEFINDER00000018749 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:10344535:10348933:1 11/11 None
ZC434.5 ENSEMBL cdna:known chromosome:CEL140:I:10344517:10349017:1 gene:ZC434.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:10344465-10348864(+) 100.0 100.0
Public Domain and Genome References
Gene Title glutamyl-trna synthetase
Gene Symbol ers-2
Ensembl ZC434.5
Entrez Gene 172904 Entrez gene
SwissProt Q23315 EMBL-EBI
WormBase CE06580 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:16074_S_AT glutamate-tRNA ligase, putative / glutamyl-tRNA synthetase, putatuve / GluRS, putative at
ATH1-121501:246845_AT glutamate-tRNA ligase, putative / glutamyl-tRNA synthetase, putatuve / GluRS, putative at
CANINE:1605426_AT similar to glutamyl-prolyl tRNA synthetase cfa
CANINE:1591379_AT similar to glutamyl-prolyl tRNA synthetase cfa
CANINE_2:CFA.21126.1.S1_S_AT similar to glutamyl-prolyl tRNA synthetase cfa
CANINE_2:CFA.222.1.S1_S_AT similar to glutamyl-prolyl tRNA synthetase cfa
CANINE_2:CFA.9625.1.A1_S_AT similar to glutamyl-prolyl tRNA synthetase cfa
CANINE_2:CFAAFFX.17037.1.S1_AT similar to glutamyl-prolyl tRNA synthetase cfa
CANINE_2:CFAAFFX.17037.1.S1_S_AT similar to glutamyl-prolyl tRNA synthetase cfa
DROSOPHILA_2:1626523_A_AT Glutamyl-prolyl-tRNA synthetase dm
DROSGENOME1:154996_AT Glutamyl-prolyl-tRNA synthetase dm
CHICKEN:GGA.8167.1.S1_S_AT glutamyl-prolyl-tRNA synthetase gga
CHICKEN:GGAAFFX.12651.1.S1_AT glutamyl-prolyl-tRNA synthetase gga
HG-U133_PLUS_2:200841_S_AT glutamyl-prolyl-tRNA synthetase hs
HG-U133A_2:200841_S_AT glutamyl-prolyl-tRNA synthetase hs
HG-U133A:200841_S_AT glutamyl-prolyl-tRNA synthetase hs
HG-U133_PLUS_2:200843_S_AT glutamyl-prolyl-tRNA synthetase hs
HG-U133A:200843_S_AT glutamyl-prolyl-tRNA synthetase hs
HG-FOCUS:200843_S_AT glutamyl-prolyl-tRNA synthetase hs
HG-U133A_2:200843_S_AT glutamyl-prolyl-tRNA synthetase hs
HG-U133_PLUS_2:200842_S_AT glutamyl-prolyl-tRNA synthetase hs
HG-U133A_2:200842_S_AT glutamyl-prolyl-tRNA synthetase hs
HG-U133A:200842_S_AT glutamyl-prolyl-tRNA synthetase hs
HU35KSUBC:RC_T96361_S_AT glutamyl-prolyl-tRNA synthetase hs
HUGENEFL:X54326_AT glutamyl-prolyl-tRNA synthetase hs
U133_X3P:G4758293_3P_A_AT glutamyl-prolyl-tRNA synthetase hs
U133_X3P:HS.55921.0.S2_3P_A_AT glutamyl-prolyl-tRNA synthetase hs
U133_X3P:HS.55921.0.S1_3P_A_AT glutamyl-prolyl-tRNA synthetase hs
HG-U95AV2:35300_AT glutamyl-prolyl-tRNA synthetase hs
HG-U95C:50382_R_AT Glutamyl-prolyl-tRNA synthetase hs
HG-U95D:85431_AT Glutamyl-prolyl-tRNA synthetase hs
HG-U95E:87985_I_AT Glutamyl-prolyl-tRNA synthetase hs
MOE430A:1452157_AT glutamyl-prolyl-tRNA synthetase mm
MOUSE430A_2:1452157_AT glutamyl-prolyl-tRNA synthetase mm
MOUSE430_2:1452157_AT glutamyl-prolyl-tRNA synthetase mm
MOE430A:1452158_AT glutamyl-prolyl-tRNA synthetase mm
MOUSE430_2:1452158_AT glutamyl-prolyl-tRNA synthetase mm
MOUSE430A_2:1452158_AT glutamyl-prolyl-tRNA synthetase mm
MOE430A:1426713_S_AT glutamyl-prolyl-tRNA synthetase mm
MOUSE430_2:1426713_S_AT glutamyl-prolyl-tRNA synthetase mm
MOUSE430A_2:1426713_S_AT glutamyl-prolyl-tRNA synthetase mm
MU11KSUBA:AA717972_F_AT glutamyl-prolyl-tRNA synthetase mm
MU11KSUBA:AA717972_I_AT glutamyl-prolyl-tRNA synthetase mm
MU11KSUBA:AA048927_S_AT glutamyl-prolyl-tRNA synthetase mm
MU11KSUBB:MSA.8404.0_F_AT glutamyl-prolyl-tRNA synthetase mm
MU11KSUBB:MSA.4728.0_S_AT glutamyl-prolyl-tRNA synthetase mm
MU11KSUBB:MSA.42914.0_S_AT glutamyl-prolyl-tRNA synthetase mm
MU11KSUBB:MSA.37214.0_F_AT glutamyl-prolyl-tRNA synthetase mm
MU11KSUBB:MSA.27168.0_AT glutamyl-prolyl-tRNA synthetase mm
MU11KSUBB:MSA.26401.0_S_AT glutamyl-prolyl-tRNA synthetase mm
MU11KSUBB:MSA.10108.0_F_AT glutamyl-prolyl-tRNA synthetase mm
MG-U74AV2:96628_AT glutamyl-prolyl-tRNA synthetase mm
MG-U74BV2:164230_AT glutamyl-prolyl-tRNA synthetase mm
MOE430B:1430370_AT glutamyl-prolyl-tRNA synthetase mm
MOUSE430_2:1430370_AT glutamyl-prolyl-tRNA synthetase mm
MU11KSUBB:MSA.6089.0_F_AT Glutamyl-tRNA synthetase mm
MU19KSUBB:TC26892_I_AT Glutamyl-tRNA synthetase mm
MU19KSUBB:TC28410_AT Glutamyl-tRNA synthetase mm
MU19KSUBC:TC35272_AT Glutamyl-tRNA synthetase mm
MU19KSUBC:TC40840_AT Glutamyl-tRNA synthetase mm
RG-U34B:RC_AI069984_AT glutamyl-prolyl-tRNA synthetase (predicted) rn
RG-U34B:RC_AI029450_AT glutamyl-prolyl-tRNA synthetase (predicted) rn
RG-U34B:RC_AA964944_AT glutamyl-prolyl-tRNA synthetase (predicted) rn
RG-U34C:RC_AI235566_AT glutamyl-prolyl-tRNA synthetase (predicted) rn
RG-U34C:RC_AI234919_AT glutamyl-prolyl-tRNA synthetase (predicted) rn
RAE230A:1373418_AT glutamyl-prolyl-tRNA synthetase (predicted) rn
RAT230_2:1373418_AT glutamyl-prolyl-tRNA synthetase (predicted) rn
RAE230B:1382040_AT glutamyl-prolyl-tRNA synthetase (predicted) rn
RAT230_2:1382040_AT glutamyl-prolyl-tRNA synthetase (predicted) rn
RAE230B:1382648_AT glutamyl-prolyl-tRNA synthetase (predicted) rn
RAT230_2:1382648_AT glutamyl-prolyl-tRNA synthetase (predicted) rn
RAE230B:1383455_AT glutamyl-prolyl-tRNA synthetase (predicted) rn
RAT230_2:1383455_AT glutamyl-prolyl-tRNA synthetase (predicted) rn
YEAST_2:1776080_AT Glutamyl-tRNA synthetase (GluRS), forms a complex with methionyl-tRNA synthetase (Mes1p) and Arc1p; complex formation increases the catalytic efficiency of both tRNA synthetases and ensures their correct localization to the cytoplasm Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6418 tRNA aminoacylation for protein translation inferred from electronic annotation QuickGO AmiGO
6424 glutamyl-tRNA aminoacylation inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5737 cytoplasm inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3779 actin binding inferred from electronic annotation QuickGO AmiGO
4812 tRNA ligase activity inferred from electronic annotation QuickGO AmiGO
4818 glutamate-tRNA ligase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB00060 Hypothetical protein ZC434.5 [Caenorhabditis elegans] ref|NP_492711.1| glutamyl(E)/glutaminyl(Q) tRNA Synthetase family member (ers-2) [Caenorhabditis elegans] 0.0
blast CAE73796 Hypothetical protein CBG21346 [Caenorhabditis briggsae] 0.0
blast XP_690524 PREDICTED: similar to Bifunctional aminoacyl-tRNA synthetase [Danio rerio] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000924 EMBL-EBI Glutamyl-tRNA synthetase, class Ic 1.0E-126
Pfam IPR000924 EMBL-EBI Glutamyl-tRNA synthetase, class Ic 2.3E-64
Pfam IPR000738 EMBL-EBI WHEP-TRS 2.5E-19
Pfam IPR000738 EMBL-EBI WHEP-TRS 2.5E-16
Pfam IPR000738 EMBL-EBI WHEP-TRS 2.8E-16
Pfam IPR000738 EMBL-EBI WHEP-TRS 8.7E-16
Pfam IPR000738 EMBL-EBI WHEP-TRS 2.9E-10
Pfam IPR000738 EMBL-EBI WHEP-TRS 2.5E-8
Sequence
Target Sequence 
>C. ELEGANS:190790_AT
ggaggagccgatattgcaggtcaaattgaagcacaaggagttcttgtcagagatttgaag
aacaaggattccaaatctcaagaaacaaaggatgctattgcgaaactcctagagctcaag
aagaactataaagaggttactggttccgattacaagccaggccctgctccagcagctgct
cccgcgaaggttacggtaccagctccatcggtctccgggggggatacactttccaagcag
attgatgatcaagcacttcttgtgagagagttgaagatgaaagacgctaaatctcaagaa
accaaggacgccatcgcaaaactgttgcagttgaagaaacagtacaaggatgcgaccggt
tcggattataagccagctccagctcaattg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGAGGAGCCGATATTGCAGGTCAAA 694 515 2833 Antisense
GATGCTATTGCGAAACTCCTAGAGC 32 413 2923 Antisense
GAGGTTACTGGTTCCGATTACAAGC 213 401 2965 Antisense
TGCTCCCGCGAAGGTTACGGTACCA 126 575 3009 Antisense
GGGGGGATACACTTTCCAAGCAGAT 572 497 3050 Antisense
GATGATCAAGCACTTCTTGTGAGAG 283 411 3076 Antisense
TCAAGAAACCAAGGACGCCATCGCA 640 629 3126 Antisense
GACGCCATCGCAAAACTGTTGCAGT 380 381 3139 Antisense
CAGTACAAGGATGCGACCGGTTCGG 39 189 3172 Antisense
GACCGGTTCGGATTATAAGCCAGCT 600 381 3186 Antisense
TTATAAGCCAGCTCCAGCTCAATTG 628 679 3198 Antisense
Sequence Source Affymetrix Proprietary Database