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[190773_s_at] tetraspanin

Description T14G10.6 /REP_DB=WormBase Gene ID /WP=CE06452 /GEN=tsp-12 /TR=Q22495 /GB=CAA93092.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=tetraspanin
Cluster 6grp_highest_10_10 > 88      6grp_high1_10_10 > 97      4grp_highest_8_8 > 39      4grp_high_8_8 > 12      6grp_highest_nonorm > 83      6grp_total > 87      4grp_total > 13      6grp_highest_sub > Da      6grp_cgc > 68      6grp_high1_sub > In      6grp_cgc_sub > In      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 163
1 2 3 4 range
A 340.9
(-3)
P 		354.1
(-2.5)
P 		340.4
(-3)
P 		502.3
(3)
P 		162
B 445.4
(3)
P 		357.2
(-2)
P 		339.6
(-3)
P 		397.2
(0.3)
P 		106
C 390.3
(-0.7)
P 		363.1
(-2.3)
P 		350.9
(-3)
P 		455.1
(3)
P 		104
avr 392.2
(-0.3) 		358.1
(-2.2) 		343.6
(-3) 		451.5
(3) 		108

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 375
1 2 3 4 5 6 range
A 464.1
(-0.9)
P 		381.8
(-3)
P 		452.2
(-1.2)
P 		474.3
(-0.6)
P 		534.6
(0.9)
P 		616.5
(3)
P 		235
B 395.7
(-1.2)
P 		409.8
(-1)
P 		284
(-3)
P 		468.8
(-0)
P 		572.7
(1.6)
P 		659
(3)
P 		375
C 365.3
(-3)
P 		451.1
(-1.1)
P 		372.6
(-2.8)
P 		434.3
(-1.5)
P 		482.4
(-0.4)
P 		637.3
(3)
P 		272
avr 408.4
(-2.1) 		414.2
(-2) 		369.6
(-3) 		459.1
(-1) 		529.9
(0.6) 		637.6
(3) 		268
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 69
1 2 3 4 range
A 124.1
(3)
P 		76.9
(-2.6)
P 		89
(-1.2)
P 		73.5
(-3)
P 		51
B 142
(3)
P 		88.2
(-2.1)
P 		78.7
(-3)
P 		84.7
(-2.4)
P 		63
C 129.2
(3)
P 		104.4
(0.2)
P 		122.3
(2.2)
P 		76.7
(-3)
P 		53
avr 131.8
(3) 		89.8
(-1.7) 		96.7
(-0.9) 		78.3
(-3) 		54

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 177
1 2 3 4 5 6 range
A 85.5
(-3)
P 		135.8
(1)
P 		98.5
(-2)
P 		120.3
(-0.2)
P 		161.3
(3)
P 		150.1
(2.1)
P 		76
B 137.7
(-0.7)
P 		136.4
(-0.7)
P 		69
(-3)
P 		124.2
(-1.1)
P 		232.7
(2.6)
P 		245.8
(3)
P 		177
C 135.4
(-0.7)
P 		137.6
(-0.6)
P 		94.8
(-2.6)
P 		87.3
(-3)
P 		156.1
(0.3)
P 		213.3
(3)
P 		126
avr 119.5
(-1.3) 		136.6
(-0.4) 		87.4
(-3) 		110.6
(-1.8) 		183.4
(2) 		203.1
(3) 		116
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 190773_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9328
Sequence Type Exemplar sequence
Representative Public ID T14G10.6 NCBI
Target Description T14G10.6 /REP_DB=WormBase Gene ID /WP=CE06452 /GEN=tsp-12 /TR=Q22495 /GB=CAA93092.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=tetraspanin
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069452(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069452 NCBI Caenorhabditis elegans T14G10.6 (tetraspanin) mRNA, complete cds. 11/11 None
SNAP00000034619 ENSEMBL cdna:SNAP chromosome:CEL140:IV:10149404:10150524:-1 11/11 None
GENEFINDER00000034632 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:10149404:10150524:-1 11/11 None
T14G10.6 ENSEMBL cdna:known chromosome:CEL140:IV:10149145:10150554:-1 gene:T14G10.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:10149409-10150530(-) 100.0 100.0
Public Domain and Genome References
Gene Title tetraspanin
Gene Symbol tsp-12
Ensembl T14G10.6
Entrez Gene 177890 Entrez gene
SwissProt Q22495 EMBL-EBI
WormBase CE06452 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1589116_AT similar to Tetraspanin-5 (Tspan-5) (Transmembrane 4 superfamily member 9) (Tetraspan NET-4) cfa
CANINE_2:CFA.12050.1.A1_A_AT similar to Tetraspanin-5 (Tspan-5) (Transmembrane 4 superfamily member 9) (Tetraspan NET-4) cfa
CANINE_2:CFAAFFX.16101.1.S1_AT similar to Tetraspanin-5 (Tspan-5) (Transmembrane 4 superfamily member 9) (Tetraspan NET-4) cfa
CANINE_2:CFAAFFX.16101.1.S1_S_AT similar to Tetraspanin-5 (Tspan-5) (Transmembrane 4 superfamily member 9) (Tetraspan NET-4) cfa
DROSOPHILA_2:1628184_AT Tetraspanin 3A dm
DROSGENOME1:144411_AT Tetraspanin 3A dm
CHICKEN:GGAAFFX.7747.1.S1_AT similar to transmembrane 4 superfamily member 9; tetraspan 5; tetraspan TM4SF; tetraspan NET-4; transmembrane 4 superfamily, member 8; tetraspanin 5; 2810455A09Rik; 4930505M03Rik gga
CHICKEN:GGAAFFX.7747.2.S1_AT similar to transmembrane 4 superfamily member 9; tetraspan 5; tetraspan TM4SF; tetraspan NET-4; transmembrane 4 superfamily, member 8; tetraspanin 5; 2810455A09Rik; 4930505M03Rik gga
CHICKEN:GGAAFFX.7747.2.S1_S_AT similar to transmembrane 4 superfamily member 9; tetraspan 5; tetraspan TM4SF; tetraspan NET-4; transmembrane 4 superfamily, member 8; tetraspanin 5; 2810455A09Rik; 4930505M03Rik gga
PLASMODIUM_ANOPHELES:209890_AT tetraspanin 5 hs
HG-U133A:209890_AT tetraspanin 5 hs
HG-U133_PLUS_2:209890_AT tetraspanin 5 hs
HG-FOCUS:209890_AT tetraspanin 5 hs
HG-U133A_2:209890_AT tetraspanin 5 hs
HU35KSUBA:RC_AA253390_S_AT tetraspanin 5 hs
HU35KSUBA:W07097_AT tetraspanin 5 hs
HU35KSUBA:W00904_AT tetraspanin 5 hs
HU35KSUBB:RC_R15108_AT tetraspanin 5 hs
HU35KSUBC:RC_W72167_S_AT tetraspanin 5 hs
U133_X3P:G3152702_3P_AT tetraspanin 5 hs
U133_X3P:HS.8037.0.A2_3P_AT tetraspanin 5 hs
U133_X3P:HS.8037.0.A1_3P_AT tetraspanin 5 hs
HG-U133_PLUS_2:225387_AT tetraspanin 5 hs
HG-U133B:225387_AT tetraspanin 5 hs
HG-U133_PLUS_2:225388_AT tetraspanin 5 hs
HG-U133B:225388_AT tetraspanin 5 hs
HG-U95AV2:40990_AT tetraspanin 5 hs
HG-U95B:46294_AT tetraspanin 5 hs
HG-U95B:46293_AT tetraspanin 5 hs
HU35KSUBB:RC_AA004443_AT Tetraspanin 5 hs
HG-U95B:47746_AT Tetraspanin 5 hs
HG-U133_PLUS_2:1562281_AT Tetraspanin 5 hs
HG-U133_PLUS_2:237194_AT Tetraspanin 5 hs
HG-U133B:237194_AT Tetraspanin 5 hs
HG-U133_PLUS_2:241060_X_AT Tetraspanin 5 hs
HG-U133B:241060_X_AT Tetraspanin 5 hs
HG-U95B:46932_AT Tetraspanin 5 hs
HG-U95B:49908_AT Tetraspanin 5 hs
HG-U95B:51809_AT Tetraspanin 5 hs
HG-U95C:56558_AT Tetraspanin 5 hs
HU35KSUBA:RC_AA054641_AT Tetraspanin 5 hs
HU35KSUBB:RC_R11505_AT Tetraspanin 5 hs
HU35KSUBC:RC_R86273_AT Tetraspanin 5 hs
U133_X3P:HS.10336.0.A1_3P_AT Tetraspanin 5 hs
MG-U74AV2:92426_AT tetraspanin 5 mm
MOUSE430A_2:1431530_A_AT tetraspanin 5 mm
MOE430A:1431530_A_AT tetraspanin 5 mm
MOUSE430_2:1431530_A_AT tetraspanin 5 mm
MU11KSUBB:MSA.8223.0_AT tetraspanin 5 mm
MG-U74CV2:129282_AT tetraspanin 5 mm
MG-U74BV2:163391_AT tetraspanin 5 mm
MOE430A:1417179_AT tetraspanin 5 mm
MOUSE430A_2:1417179_AT tetraspanin 5 mm
MOUSE430_2:1417179_AT tetraspanin 5 mm
MG-U74CV2:140325_AT Tetraspanin 5 (Tspan5), mRNA mm
MG-U74CV2:140665_AT Tetraspanin 5 (Tspan5), mRNA mm
MOE430B:1441467_AT Tetraspanin 5 (Tspan5), mRNA mm
MOUSE430_2:1441467_AT Tetraspanin 5 (Tspan5), mRNA mm
MOE430B:1447600_AT Tetraspanin 5 (Tspan5), mRNA mm
MOUSE430_2:1447600_AT Tetraspanin 5 (Tspan5), mRNA mm
MOE430B:1459774_AT Tetraspanin 5 (Tspan5), mRNA mm
MOUSE430_2:1459774_AT Tetraspanin 5 (Tspan5), mRNA mm
MU19KSUBA:TC19770_AT Tetraspanin 5 (Tspan5), mRNA mm
MU19KSUBA:TC19770_G_AT Tetraspanin 5 (Tspan5), mRNA mm
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA93092 Hypothetical protein T14G10.6 [Caenorhabditis elegans] ref|NP_501853.1| T14G10.6 [Caenorhabditis elegans] 1.0E-161
blast CAE59923 Hypothetical protein CBG03409 [Caenorhabditis briggsae] 1.0E-131
blast AAH74249 Tm4sf9 protein [Xenopus laevis] 3.0E-53
Protein Domains
Database ID Description E-Value
Pfam IPR000301 EMBL-EBI CD9/CD37/CD63 antigen 5.5E-79
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_501853.1 4 43-65,85-107,114-136,268-290
T14G10.6 4 43-65,85-107,114-136,268-290
SNAP00000034619 4 43-65,85-107,114-136,268-290
GENEFINDER00000034632 4 43-65,85-107,114-136,268-290
Sequence
Target Sequence 
>C. ELEGANS:190773_S_AT
tccttccttacattctattcaacacttcttggccttttgctcatcgccgaattctcagca
ggagtattcgcatatgcttgcagagatcaacttgataactatattagaaatctattgaac
gatgtggtagttggatatagagatgatccggatcttcagctattgattgattctatgcaa
gagacgtggatgtgttgtggaatcaacggagccgacgattgggatagaaacacctatttt
tcaatagaagccagagaagtggcctctccagaagctggcggagttccattttcctgttgt
atcaacagtagtaaactggaattcaagaactacttctgcgggcacggtgttcgtttaaaa
ccagaaagccacatggcagcacatcttgcggctcaacgtgtgatggcccacactgcatcg
atttatacggaaggatgtctgccgaaacttcaactttggcttaataataacatgctatta
gtagccgtttcgatggttattattgcaataatccaggttctcggtatctgtttcgctcaa
aa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCCTTCCTTACATTCTATTCAACAC 646 591 346 Antisense
CTATTCAACACTTCTTGGCCTTTTG 661 223 360 Antisense
TCATCGCCGAATTCTCAGCAGGAGT 62 623 386 Antisense
GATGATCCGGATCTTCAGCTATTGA 470 411 487 Antisense
CGGAGTTCCATTTTCCTGTTGTATC 79 243 624 Antisense
TTCTGCGGGCACGGTGTTCGTTTAA 464 693 679 Antisense
AAAGCCACATGGCAGCACATCTTGC 188 125 710 Antisense
TTGCGGCTCAACGTGTGATGGCCCA 470 703 731 Antisense
GCCCACACTGCATCGATTTATACGG 493 287 751 Antisense
GGATGTCTGCCGAAACTTCAACTTT 5 513 778 Antisense
TTCTCGGTATCTGTTTCGCTCAAAA 622 691 863 Antisense
Sequence Source Affymetrix Proprietary Database